Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BOD1P1
Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr18:3415156-3416166  UCSC
Coordinates (T2T) chr18:3574533-3575543  UCSC
Coordinates (hg19) chr18:3415154-3416164  UCSC
Strand +
Parental Sequence NM_138369.3
Parental seq. overlap 833 bp
Parental seq. overlap (%) 42.7%
Genomic Region Intragenic (TGIF1)
Retrocopy Summary BOD1P1, located on chr18:3415156-3416166, is a retrocopy of the parental gene BOD1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BOD1
Full Name biorientation of chromosomes in cell division 1
Also known as FAM44B
Coordinate chr5:173607145-173617072
Strand -
Gene summary Enables protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Involved in mitotic sister chromatid segregation; negative regulation of phosphoprotein phosphatase activity; and protein localization to chromosome, centromeric region. Located in centrosome; spindle microtubule; and spindle pole. Part of outer kinetochore. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BOD1P2
Bonobo Pan paniscus BOD1P2
Gorilla Gorilla gorilla BOD1P2
Orangutan Pongo abelii BOD1P3
Gibbon Nomascus leucogenys BOD1P2
Green monkey Chlorocebus sabaeus BOD1P4
Crab-eating macaque Macaca fascicularis BOD1P4
Rhesus Macaca mulatta BOD1P4
Baboon Papio anubis BOD1P4
Golden snub-nosed monkey Rhinopithecus roxellana BOD1P3
Marmoset Callithrix jacchus BOD1P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BOD1P1
TCTGCCTTCCGGCGACCCGGAGCTCATTGCTCTCATCCTGGAGTGGCTCAAGAGCCAGGCCCGTTTGGCAGCTTCTGTCGATGCTGCCTGGCCCCTGTGGACACCAAGCCAGCTTACCAAAACCAGAGGCAGAAAGCTGAGGGTTCGGTGTCCACACACCTGGATGAGCAGAACTGGAATCTTATGATGCGCAAAAGCCTATTGCGAAATGGTCAGAGGCAGAGTGAGATTCAGTCAGGGACATTGGAAGCTGGAGTAGACAGGGTTATTTCTCAGGCAGAGGATCCAAAATTAAACCACATCCTCAGGCCACCAACGGAAGGAGCAAGTCATGAGTTCCTGGGTGCCCAGAAGACAGCAATGGTGCCAGCACCCCCTTTAGAGCCCGCAGACCAGGACCCTCCAGCTCCAGCCTAGGGCGGTTCTCAGGAACATGCCCAACGCCTTTTGAAAGCTCTATTTAATTATCGGTGAAGAAGTGACTTTGGTTACATAAGAGTGCAACTTCAGAATGAAGATAGGCCAAGGTCTCACTGATTTCAAGATTTCGGCCTTGACTGTGGGCAGTGTCCAAGTTTGAATGGGGGGCAAGTTTGGCAGTGGGGATGTTGACCAATTTGTCCCCTGCATTGTGCTGCCATTTGGTCAGCCTGTCCAAGGATACAACACCCGGTAGACACTACAGAGAGATAAAGAAACACTATAGTAACTTGGGATTGTCCTAAAACAGACTTTTATACTTGAACGTGGAGTCTCTGTGTGGACTTTAGAGTTTGTGCTCTGGAATATACCAAAGCTACAGTTTGAGAGAAAGTAACCAGTCCCAAAGATAATTTCAAAGAACAATAACAATATAAAGGGTGGCTGGGAGTAGGTATTTGATGGTGCTTATTTGATATTGTTTCTCAGAGTTGCAAACTGGAATGTAGAAACCACTAGCATCAGATATCTAGAAAGTTGTTATGACCTTCTTGTACATGAATCTTCTAGCCAGTTTCCTTTCCCTTGTAA
>NM_138369.3
GTTTCTGCCGCGTCCACCACAACCTCTGCTGTATCAGAGGGGGCCTTcgccgccgccgcccccaccaccgcccctgccgccatcgccacctccgccgctgccgccTTGGGGCCCTCCTCCTTCACCGCCCCCTTCACCACCTCTACACGTTCTAGGCCTTCTGTCCTGGAGAAGAAGCTATAGTCGTTCTCCCTTGTGGGCCCGGGGCGCAGCCATggcggacggcggcggcggcgggggaactggcgcggtgggcggcggcggAACTAGCCAGGCCTCTGCCGGGGCAGCGACTGGCGCTACTGGGGCCAGCGGGGGCGGTGGCCCCATCAACCCGGCCTCGCTGCCTCCCGGCGACCCGCAGCTCATCGCTCTCATCGTGGAGCAGCTCAAGAGCCGGGGCCTTTTTGACAGCTTCCGCCGGGACTGCCTGGCCGACGTGGACACCAAGCCAGCTTACCAAAACCTGAGGCAGAAAGTGGATAATTTTGTGTCAACACATCTGGACAAGCAGGAATGGAATCCTACGATGAACAAAAACCAGTTGCGAAATGGTCTGAGGCAGAGTGTGGTTCAGTCAGGGATGTTGGAAGCTGGAGTAGACAGGATTATTTCTCAGGTGGTGGATCCAAAACTTAACCACATCTTCAGGCCACAAATAGAACGAGCAATTCATGAGTTCCTGGCGGCCCAGAAAAAAGCAGCTGTGCCAGCACCCCCTCCAGAGCCCGAAGGCCAGGACCCTCCAGCTCCATCTCAGGACACTTCCTAAGAATACGCCAGACACCTTTTGAAAGCTAATTTTTGGTGAAGAAATGGATTCGGTTACATAAGAGTGCAACTTCAGACTGAAGATAGGCCAAGGTCGTCACTGATCTCAAGATTTCAACCTTGACCATGGGCAGTGACCAGATTGAAAGGGGAGCAAGTTCGGCAGTGGGAGAGTTGACCGTGTCACCCCCTGCATTGTGCTGCCATTTGGCCAGCCTGTCCAAGGGCATGACACCAAGTAGACACTACAGAGAGAGAAACACTACAGCAACCCAGGGTTGTCCTGAAACAGACTTTTATACTTGAACATGGAGACTGCACATGGACTTTAGGGTTTGTGCTGTGGGATAAACGGAAGCTACAGTGAGAACATAGCCAGTCCCAAAGACAATTTCAAAGAAAAATGACAGTAAAGATTAGCTGGGAGTAGTCTTTGACAGTGCTTATTTGATACTGTCTCTCAGAGTTTGCAAACCAGATTGTACAAGTCATTAGCGTCAGATAGCTTTAAAGTTGTGACCTTCTTGTACATGAATCTTCTAGCCAGTTTCCTTTCCTTTGTAACGAAACATGAAATCCTAGAATGTATGAGAAGTTCAGACATTAGGCATAAGGAAACTCGTTTGCAGGCTCTCTGTCCAGGGCTGCTTCCTGTCCTGGAGGGGCCAGTGAGTCTTAGGTATGTTTATTTTATTCTCACATTTGTGTTTTTTTAGAAAAGTGAATGGTCAATAAATGGCTTATCTTTCATAATAAAATTATTTGATACTTTTACTCCGAAGCTTCAGCTGAAGCTTAAACCTCAGGTCTGTGAAGGGCAACCTTTGTCTTCTGCCTCTGTGCACCACACATGATCTACTGGCAGTGAAGATTGGTACATATAACTTGGAACTATGAAACTAGTAGGTGTAGCTAGTAGTGGGCTGTTTCTCTCCTCCCTGAGCCATTACTGACACTGGTCTTTAGTTGAGGTAGTCCGTGGTATGTGTcagtgtttgtcatccttgtgtgtgcagaagtagcacctggggatttaagggaaaatgcatatttctgattaagaagttctggggtgggacctaagagtgagtgtttctgacaagctgccaggtgatgctgatgctgccaggcctctgaacatactctgtat

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