Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name POLR3GP2
Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr18:48478295-48480439  UCSC
Coordinates (T2T) chr18:48669099-48671243  UCSC
Coordinates (hg19) chr18:46004666-46006810  UCSC
Strand +
Parental Sequence NM_001370354.1
Parental seq. overlap 1880 bp
Parental seq. overlap (%) 52.9%
Genomic Region Intergenic
Retrocopy Summary POLR3GP2, located on chr18:48478295-48480439, is a retrocopy of the parental gene POLR3G. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name POLR3G
Full Name RNA polymerase III subunit G
Also known as C31|RPC32|RPC7
Coordinate chr5:90473929-90514557
Strand +
Gene summary Enables chromatin binding activity. Involved in positive regulation of innate immune response; positive regulation of interferon-beta production; and transcription by RNA polymerase III. Acts upstream of or within cell population proliferation. Located in cytosol and nuclear body. Part of RNA polymerase III complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes POLR3GP2
Bonobo Pan paniscus POLR3GP2
Gorilla Gorilla gorilla POLR3GP2
Orangutan Pongo abelii POLR3GP2
Gibbon Nomascus leucogenys POLR3GP1
Green monkey Chlorocebus sabaeus POLR3GP1
Crab-eating macaque Macaca fascicularis POLR3GP1
Rhesus Macaca mulatta POLR3GP1
Baboon Papio anubis POLR3GP1
Golden snub-nosed monkey Rhinopithecus roxellana POLR3GP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>POLR3GP2
AGGTCCTACAAGAGGCCAGAGGAGTACAGGTACTCAGGGAGGCTGTGCAGCCCCAGGCCTGTATCAATCACCACGTCCTGCTTGGAGCCATGCACCAGCCAAATGTTGGCATGGTTGCCCGACTCATAGAAGTGTTCTTGAATTCAAAAGATACTACCACCTGGAGACTTGTGGGTGTACCACTTGAGCGCCAACATGCTGGGCATGGGTGCAGCCAGGCAGATGCCTTTCAGAATTTGCCCACTCGTCTAGTATAACTAGATCTGATGGCTGGGAATAAAGGAAGAGGAGGATGTGCTGCTCATACCTTTAATACTGAGGCTGTTGGATTTAGCAAAGGTGAAAAGTTACCTTATGTAGTGTTGAAACCACCCCCACTATTTCCTGATGCAGATTATAAATCAGTGCCACTGAAAACAGAAGATGAAGAATACATGCTGGCTTTGAAACAGGAGTTGAGAGAAACAATGAAAAGAATGCCTTATTTTATTGAAACACCTGAAGAAAGACAAGATATTGAAAGGTATAGTAAAAGATACATGAAGGTATATAAAGAAGAATGGATACCAGATTGGAGAAGACTTCCAAGAGAGATAACGCCAAGAAATAAATGTAAAAACACAGGCCCAAAACCCGAAAAGGCAAAAGACGCAGGCAAAGTCACCTCACTAATACTTCAGATGTGTTGAAAAAAATTGAGGAATTGGGAAAGAAAGGTGATGGTGAAAATTCAATGACTACATTAATTCATAATTCGAAGATGGAAATGATTTTGGCCCAGACAGTGATGACAACATGGATGAAGCAACCTATTAGGCATGAAATTTTTCAAAAAGTATTTTTATGATGCAGCTTCTGAACATTTGGACAGATTTGTTTTGTATTTTTTTCTGATAAGGAATAAGTATTTTTGTTTTTTTTTTTTGGACAAATATTTGTTACCAAAATATTCAAAACCACTTTGAGTTTACACACTAATTACCTTACAAATTAGTCCCTGACACTCTGACCTTCCTTCTAAACACCTCTGCCATCTCTCTTATGTACTCTTGTGGGTTTTTTTGTATTATTTGAATAGGAATGTGCCTAAAGAATTTTTGCTCTCTTAATCTATGTATACATACTTGAAGAAATCATGCTTGCTTAACTGCTGATTTTTTGTAAAACTATTACCAGTCATAGTGGATTTCTGTAACCTGAAAGTTGATATAATACAGCACATGGAGCACTTTAAAAACAAACTTGAAAATAATTTTATTTTTTACTTTTACATGGTATGTTCTAGACTACTGCATTATGACTACATAAACCAACCTGGGCTTTTATAAGTACAGAATTGTGAAATAGAGGTTTTGTGATGGAAAACATAGACACAGGGAAAAATACCAAACTGAGCAATATAAATTTCACGGCTCACATCTTAGCCAGTACAAAGAAATTTTCACATGGGGTGAATATTATAAATACTGGAACTGGGGACTAACTTAATACTGTATGATGTATGAATTAATTATTCCACTGTAATAACTGTGACATCTTCAAATAGTTGGGCTTATGAAAAATTTGACTAAGACATTTTAATTTTAAACTTTATGTAAATGTGAAATAAGTTCTGGTCATATAAATATCACTGTAGAATGCATGTGTGTGAACTCTATGAAGTGTGGTGGCCTTTTATGTTTCAGAGTACTCAAGCTGTACAATTGATTTATATAAACATGCAAGATGAACTCAGGTCATTTTGAAATTAAGATTAATTTTTTTGTTGTTTAAAGCTAGCTCCCCTAACTTTATATATTTTTTGGGAAAAAAAAATACCTAAAAACCTCAACCTAAAAAGACTCACAAATGCCAAACATTTTCAAGGAAATTTATATTATATATTTCAAAAATGATTTATCAATGTTATCTACCAAAATAAATACTTTTATTTTTCCCCTTTGGGAAGATATCATTATCCTCTAATGTGAGAATCAGATCCCTAGATTCTATTTCTACCTGTACTATTAAACTCAACCTTGAGCC
>NM_001370354.1
CGGAAAGCCAGGTCACGGTCTCAAAGTTGTCCCCGCGAGCCAGCGCCTCGGCCTCGGCGTGGTGCACTGCCACGCGGTCGAACTGGTAGAGGCCGCCGGAGTGGTCGAAGTGCACGTGGGTGGCCACGGCAAGCAGTGGCCGGCGCGCCGCGTCCTCTTTGGCCTCTCGGTCCTGCAAGAGGCCGGAGGAGTACAGGTACTCCGGGAGGCTGCGCAGCCCCAGGCCTGTATCGATCACCACGTCCTGCTCGGAGCCGCGCACCAGCCAGATGTTGGCACGGTTGCCCGACTCGTAGAAACGTTCTTGAATCCAGAAGATACCATCGCCTAGAGACTTGTGGGCGTACCACTCGAGCGCCGACATGCTGGGCAGGGGTGCAGCCAGGCGGGTGCCTTTCAGAATTTGCCCACTCATCTGGTATAACTGGTTCTGATGGCTGGGAATAAAGGAAGAGGACGTGCTGCTTATACCTTTAATATTGAGGCTGTTGGATTTAGCAAAGGTGAAAAGTTACCTGATGTAGTGTTGAAACCACCCCCACTATTTCCTGATACAGATTATAAACCAGTGCCACTGAAAACAGGAGAAGGTGAAGAATATATGCTGGCTTTGAAACAGGAGTTGAGAGAAACAATGAAAAGAATGCCTTATTTTATTGAAACACCTGAAGAAAGACAAGATATTGAAAGGTATAGTAAAAGATACATGAAGGTATACAAGGAAGAATGGATACCAGATTGGAGAAGACTTCCAAGAGAGATGATGCCAAGAAATAAATGTAAAAAAGCAGGCCCAAAACCCAAAAAGGCAAAAGACGCAGGCAAAGGCACACCACTCACTAATACTGAAGATGTGTTGAAAAAAATGGAGgAATTGGAAAAAAGAGGTGATGGTgaaaaatcagatgaggaaaatgaagagaaagaaggaagcaaagagaaaagtaaagaaggtgatgatgacgatgacgatgatgccgcagaacaggaggaatatgatgaagaagagcaagaagaGGAAAATGACTACATTAATTCATACTTTGAAGATGGAGATGATTTTGGCGCAGACAGTGATGACAACATGGATGAGGCAACCTATTAGGCATGAAATTTTTCAAAAAATATTTTTATGATGCAGCTTCTGAACATTTGGACAGACTTGATTTGTATTTTATTTCTGATAAGGAATAAGTACTTGTTTCTGTTGTTTTGGACAAATAGTTGTTACCAAAATATTCAAAACCACTTTGAGTTTACATACTAGTTACCTTAAAAATTATTCCCTGACACTCTGACATTCCTTCTAAACACCTCTGCCATCTCTCTTATGTACTCTCATGGGTTTTTTTGTATGATTTGAATATGAATGTGCCTAAAGAATTTTTGCTCTCTTAATCTATGTATACATACTTGAACAAATCATTCTTGCTTAACTGCTGATCTTTTGTAAAACTATTGCTAGTCATAATGGATTTCTATAACCTGAAAGTTGATATAATACAGCACGTGGAGCACTTTAAAAACAAAGAAACTTGAAAATAATTTTATTTTTTACCTTTACATGGTGTGTTCTAGACTACTGCATTATGACTACATAAACCTACCTGAGCTCTTACAAGTACAGAATTGTGAGACAGAGGTTTTGTGATGGAAAACATACACATAGGGAAAAATACCAAACTGAGCAATATAAATTTCACAGCTCACATCTTAGCCAGTACAAAGAAACTTTCACATGGGGTGAATATTATAATACTTGAATTTGAGACTTAATACTGTATATGAATTAATCATCCCACTGTAATAACTGACATCTTCAAATAGTTGGGCTTATGAAAAATTTGACTAAGACATTTTATTTTATACTTTATGTAAATGTGAAATAAGTTCTGGTCATATAAATATGTAGAATGCATGTGTGTGAACTCTATGAAGTGAAGTGTGGTGGCCTTTTATGTTTCAGAGTACTCAAGTGTACAATTGATTTATATAAAAATGCAAAATGAACTCAGGTCATTTTGAAATTAATATTAATATTTTTGTTGTTTAACTTTAAAGCTAGCTCCCCTAACTTTATATATTTTTTGGGAAAAAATACCTAAAAACCTCAGCCTACAAAGACTCTCAGAAATGCCAAAGATTTTCAAGGAAATTCATATTATATATTTCAAAAATGATTTATCAATGTTATCTACCAAAAGAAATAATTTTATTTTTCCCCTTTGGGGAGATATTATCCTCTAATAtgagaatcagatccctagattctatttctacctatactattaaactcaaccttgaacctgagcttggttgtttctgtgccttagtttctccactcgtaaaCAATTTCCTATAAAAATTGTTTAAACACCAACCAAAATTTACCATATGTATTCATTCTCTTGCCTTAAAGATCACTTCTTAACTTACATTTGGCTCTCACCCTCTAAAAATTTGTAGTTTGGAGAGTAACTGAAAGCACAATTTTAAGAAACATGTTTTCCTCACAAAATATATTGTAATCTGATTTTCCTATCTTGTATTCATGCAGAAAATTGGAGAAAATGTGTATTGTCTTGTGCCATTCTGCAATATGAATTTCTCAGGAAAAAGATGTTTCAATGGCAATACTTTCTTAAATAATTCAAGATGGGTGTGAGGACCTATCTTATTAGTTTAGTGCTGTGTTAACCATTTGTGAATTACTTCTTGTTTAAAGGAAGTTGTCAAAAAATTTTAAGATTCTAAATGGAATACACGAATAAAGTAAGCCTTAGAATAGAAACCTCACAAAAAGTTGTCATTTGCGGTTGATAATTAACATAGGTGTTTTATTCTCTCAACTCCTTAGTACCAGAGCCAAATACAATTTAGTTTTCAGAAATCTTATCAATATTGTTCTATTTACCTACTTATAAATCTGCAGATAACCACTTGAACCAGGCAAATACACTGAAGATAAAGGTTATTTCTTTTTTTAGCTTTGAATTTGTCATGACCATTTTAGTCTTGCAGATAGCAGGGCAGCCCCTTGGGGCAAGGATTTACTCTGGGAGGTACCGTTAAGAGCCTTCTTTCCCCCTTTGAAAGATCCTTTTACAATGTTAAAGTATACTAGTTGCAAGAACAAGCAGGATTTGCAGGTTGCTTTACCAGCATGAGTCTCATTTTTCTGGCTTAAAATCTGGGACTGTGAAATTATTCCATAGGAAAGTGAATGTTATTTTGCAGAATTAGCCTCTTACATAAAAGTATTTGTTGAAGTGTCTTTAAAATTGCTATCATGAGCAAAACTGGTTGCTGTAATGCTTGTTTTTCTGTATTTATTTACACATTAAATTCTTACAAAACAAAATGTGTTCGTTTGTTTTATAGTAAGATGTTTTATTTTGAACTTATTTAAATGTTTATTTGTTAGAGAAAACTAATTTGTTAATATAGATCTTAACTAGTAACTATTAAGCAGGGATGTTTGTTCCAAATATTCTTGAATAAACAATCACCACAAACAACAAAA

Publications

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