Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NET1P1
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Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr18:51434466-51434650  UCSC
Coordinates (T2T) chr18:51637375-51637559  UCSC
Coordinates (hg19) chr18:48960836-48961020  UCSC
Strand +
Parental Sequence NM_001047160.3
Parental seq. overlap 150 bp
Parental seq. overlap (%) 3.8%
Genomic Region Intergenic
Retrocopy Summary NET1P1, located on chr18:51434466-51434650, is a retrocopy of the parental gene NET1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NET1
Full Name neuroepithelial cell transforming 1
Also known as ARHGEF8|NET1A
Coordinate chr10:5412557-5459056
Strand +
Gene summary This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NET1P1
Bonobo Pan paniscus NET1P1
Gorilla Gorilla gorilla NET1P1
Orangutan Pongo abelii NET1P1
Gibbon Nomascus leucogenys NET1P1
Green monkey Chlorocebus sabaeus NET1P1
Crab-eating macaque Macaca fascicularis NET1P1
Rhesus Macaca mulatta NET1P1
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Related Sequence

>NET1P1
TAGTCTAAGAGCTAGTCTTTGAAGACCTGAAGGATGGAGATGTGAGAATGAGAAAGTCCTTTTGAAGATGTTTCTGTAATTCAGATAAAGCTAAAAATATCTTTGTAGTTTGCTTCCAAGACCCTTCTTTGGGCCAGTCTCACACTCCATAAGTCTAAGATGTGTTTCATAAGCAGCAGTGGTTC
>NM_001047160.3
AAATCCCCGGATGACGGCGGTGGCGGCTGCAGTCCGCTGACAGGCGCTTTCTGCCTGGCAGAGGCTGGCGGGCATCGTGCCCGTCCCTGCCGGTCTCCCGGGCACCCGGCCACCGCCCCACCCCCTCCTCCGTGCCATGGAGCCCGAGCTGGCGGCTCAGAAGCAGCCTCGACCGCGGAGGCGAAGCCGCCGGGCCTCTGGGCTCAGCACGGAGGGAGCGACGGGGCCTTCGGCCGACACCTCCGGGTCGGAGCTGGACGGGAGATGTTCCCTTCGGAGAGGCAGCTCCTTCACATTCTTAACACCTGGCCCCAACTGGGACTTCACTTTGAAAAGAAAACGCAGAGAGAAAGATGATGATGTTGTAAGCCTTAGCAGCCTTGATCTGAAGGAGCCAAGCAATAAAAGAGTTCGACCTCTGGCTCGTGTCACGTCCTTGGCAAATTTAATCTCTCCTGTAAGAAATGGAGCTGTCAGACGTTTTGGTCAAACAATACAGTCATTTACCCTTCGTGGTGACCACAGATCCCCAGCCTCTGCCCAGAAGTTTTCTAGCAGGTCAACAGTCCCAACACCCGCCAAGAGAAGGAGCAGTGCACTGTGGTCAGAGATGCTGGACATCACCATGAAGGAGTCTCTCACCACCAGGGAGATCAGACGGCAGGAGGCAATATATGAAATGTCCCGAGGTGAACAGGATTTAATTGAGGATCTCAAACTTGCAAGAAAGGCCTATCATGACCCCATGTTAAAGTTGTCCATCATGTCAGAAGAGGAACTCACACATATATTTGGTGATCTGGACTCTTACATACCTCTGCATGAAGATTTGTTGACAAGAATAGGAGAAGCAACCAAGCCTGATGGAACAGTGGAGCAGATTGGTCACATTCTCGTGAGCTGGTTACCGCGCTTGAATGCCTACAGAGGTTACTGTAGTAACCAGCTGGCAGCCAAAGCTCTTCTTGATCAAAAGAAACAGGATCCAAGAGTCCAAGACTTCCTCCAGCGATGTCTCGAGTCTCCCTTCAGTCGAAAACTAGATCTTTGGAGTTTCCTAGATATCCCTCGAAGTCGCCTAGTCAAATACCCTTTACTGTTAAAAGAAATTCTTAAACACACTCCAAAAGAGCACCCTGATGTTCAGCTTCTGGAGGATGCTATATTGATAATACAGGGAGTCCTCTCTGATATCAACTTGAAGAAAGGTGAATCCGAGTGCCAGTATTACATCGACAAGCTGGAGTACCTGGATGAAAAGCAGAGGGACCCCAGAATCGAAGCGAGCAAAGTGCTGCTGTGCCATGGGGAGCTGCGGAGCAAGAGTGGACATAAACTTTACATTTTCCTGTTTCAAGACATCTTGGTTCTGACTCGGCCCGTCACACGGAACGAACGGCACTCTTACCAGGTTTACCGGCAGCCAATCCCAGTCCAAGAGCTAGTCCTAGAAGACCTGCAGGATGGAGATGTGAGAATGGGAGGCTCCTTTCGAGGAGCTTTCAGTAACTCAGAGAAAGCTAAAAATATCTTTAGAATTCGCTTCCATGACCCCTCTCCAGCCCAGTCTCACACTCTGCAAGCCAATGACGTGTTCCACAAGCAGCAGTGGTTCAACTGTATTCGAGCGGCCATTGCCCCCTTCCAGTCGGCAGGCAGTCCACCTGAGCTGCAGGGCCTGCCGGAGCTGCACGAAGAGTGTGAGGGGAACCACCCCTCTGCGAGGAAACTCACAGCCCAGAGGAGGGCATCCACAGTTTCCAGTGTTACTCAGGTAGAAGTTGATGAAAACGCTTACAGATGTGGCTCTGGCATGCAGATGGCAGAGGACAGCAAGAGCTTAAAGACACACCAGACACAGCCCGGCATCCGAAGAGCGAGGGACAAAGCCCTTTCTGGTGGCAAACGGAAAGAGACTTTGGTGTAGAGAAGGCTCTGTGTGTTAACTGATGGGAGAGACTGTTTGTTTATAAATGTGTACAGTTTTGTTTTCTCGTAAGGGGAGCATCATAGGGTTACTTTATACCAGTTGTAACATTTTCATTGTTTTTGGTTGTTCTTTTTTCTTTTTTTAATGGCAGCTAAAGATATACAGATTACTGTTAAATTGCAGTCCTTTTTTTTTTAAAGATATTTTCTTGAATTATTTAGAACATGGTAAGCCTGGTATTTTTTAATCAAACAAAATATTTATGAAATGGGTTTTCTCTTAATTCTGGATTCATCATGGCTTTCTAATACCAATTGTAATATTTACAATATTCACCAAAACTTAGAATTTTGCAAATGCTGGAATTCTGCCAGTGTTTCTTTGCTAAGCCTTGCATGCAAAATTTGAAATTTTAACATTGGCACCCAAAACCTACATGGAATGTATGTCTGGAGTATTTCAAACTTTACATTGAAACATAATTTCCTTGGAAAACAAACCATAAGCCTGAGGAGGTTTTTATCAACTGGAATGCTTTATATTAGTTTGTTTTTCACTGTACATTCCTCATTTTACATTCATTTAACCTGCCGATTATTTAATTTTTTTATTGTAAAGTAGTTTTTAGCATTTGCTTTTATTTTTTTACTTTGATGCCTTTTCAAATTGGCATGTCTTTAAAGTATTTTTCTTCCTGATTAAAAAtgtgtgtgtatgtgtgtgtgtgtgtgtatatatatatatatTTTTAAATCACATTAATTTTACCAAGTGAAACCAAGCCATACTGTTTTTGAGCCAATTAAGAAAATTGCCATTTTTAAAGTGTAGCATTTCAGGGTAAAGACCCATGAAATGGCTTGATGTATTCTAGACTACTGAAAGAAAACCACTTCAAAGATTTTGTTGAAAGTTTTAGTGTTGTCTGAAATGCAAGAGGGAAGGTGATTGGTAGTGAGTTAAAAGAAAAAGAGaggaaaagagagtagttttgtcttcaagtaaaatgtctggttgtgccagacatttcacaagtgtgaaaggagataggagaagctcaacttgagggcgtgtagtaagttgtagaaggctcgaggggacgtggacttatttgccttggtttgcaatacctgcaaataatgagtttgaaaagaaacaatgaaatgtgttaaaaatttgaccatattagataaattttcgtggatttagtcataagatggaaaaagactggtgaatcttttattacaaaatgttTCTGTTAAAATGGGATCATCATCTTTGAAAGGGGGGAGGAGGAGTAAAAGCCCGATTATAATGGTGATCAATTCAAGTCAGTGTTGACTATTCTGTGAAATATATTTGGCCAGTGGAAATGATAATCAGAAAAGACTGTAAATAGATCCATCCAAATGATTTCTCTGTACAAATGAATGATACTATTAAAAAAAAAAAAAGCACACACATAATCACCCTGAAGGTTTCTTGCCTGGTGGCTATGTTGGGGGCATTTGGCAAAATATGCTGGTGTGGCAAAGGAGGTAGTGGTAAGCCTCATAAAAGTTAGTAAAAATTGTAGTTCAACCTTTGAAATCATTGATGAATCAGCGAAAGGTAGGTAAGTCTTGTGTTAGGAAATCTTTTAAGAACATGGTGTAATCAGACACAGCAATTGTATTGAAAATAACTGAACACCTGTTACTTTCTGGATAGGATAGTAAGGGTAGTAGTGGCAAAGGATCCTGATTAATTTCAGATTTTAATGTAAGTACCTCAGGTTCTTGTCTTTGGAAATTCACATTCATAAGTGTATATTACACCAATGATTGTGATCTGCAACACCAGAAAGCAAGATTTCTAATCATTTCCAGAGGTGTTGTATAGAATAGTTATTCCAGAGTTACCTTGATCAGCTTCTGAAGTTTAAGAAGCAAGTAATAGTTCAAGTGTTGTTAATGGAATTATGTTTTATTTAAAACCGTATCTTCTTTTGGTTCCCTCAAAGGTAAAAATAAGACCCAGAATCTGAGTAAATCTATTAAATGAATGTTCTTCAGAAATA

Publications

PMID - Link Title
No publications available for this retrocopy