Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name UBA2P1
Wait
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:87044269-87045871  UCSC
Coordinates (T2T) chr1:86884870-86886472  UCSC
Coordinates (hg19) chr1:87509952-87511554  UCSC
Strand -
Parental Sequence NM_005499.3
Parental seq. overlap 1524 bp
Parental seq. overlap (%) 38%
Genomic Region Intragenic (HS2ST1)
Retrocopy Summary UBA2P1, located on chr1:87044269-87045871, is a retrocopy of the parental gene UBA2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name UBA2
Full Name ubiquitin like modifier activating enzyme 2
Also known as ACCES|ARX|HRIHFB2115|SAE2
Coordinate chr19:34428176-34471251
Strand +
Gene summary Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes UBA2P1
Bonobo Pan paniscus UBA2P1
Gorilla Gorilla gorilla UBA2P1
Orangutan Pongo abelii UBA2P1
Green monkey Chlorocebus sabaeus UBA2P1
Crab-eating macaque Macaca fascicularis UBA2P1
Rhesus Macaca mulatta UBA2P1
Baboon Papio anubis UBA2P1
Golden snub-nosed monkey Rhinopithecus roxellana UBA2P1
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.10.20.30.4
log10(TPM+1)

Related Sequence

>UBA2P1
GAGACTCTGAGAGTTCATTTAGCAGAAAAGGGGGATGGAGCTGAGCTCACATGGGATAAGGATGACCCATATGCAATGGATTTTGTTACCTCTGCTACAAACCTCAGGATGCATATTTTCAGTATGAATATGAAGAGTAGATTTGATATCAAATCAGTGGCAGGGAATATTATTCCTGCTATTGCTACTACTAATGCAGTGATTGCTGGGTTGACAGTATTGGAAAGATTGAAGATCTTATCAGGAAAAATAGACCACTGCAGAACAATTGTTTTGAATAAACAAGCAAATCCAAGAAAGAAGTTTCTTGTGCCTTGTGCACTGGATCCTCCCAACCCCAATTGTTACATATGTGCCAGCAAGCCAGGTGACTGTACGGCTGAATGTCCATAAAGTGACTGTTCTCACCTTACGAGACAAGGTAGTGAAACAAAAATTTGCTATGGTAGCACCAGATGTCCAAATTGAAGATGGGAAAGGAACAATCCTAATATCTTCTGAAAAGGGAGAGACAGAAGCTAATAATCACAAGAAGTTGTCAGAATTTGGAATGAGAAATTGCAGCTGGCTTCAAGCAGATTACTTCCTCCAGGACTATACTTTATTGATCAACATCCTTCATAGTGAAGACCTAGGAAAGGATGTTGAATTTGAAGTGTTGGTGATGCCCCAGAAAAAGTGGGGCCAAAACAAGCTGAAGATGCTGCCAAAAGCATAACCAATGGCAGTAATGATGGAGGTCAGCCTTCCACCTCCACAGCTCAAGAGCAAGATGATGTTCTCACAGTTGATTCGGATGAAGAAGATTCTTCAAAGAATGCTGACGTCAGTGAAGAAGAGAGAAGCCGCAAGAGGAAATCAGACGAGAAAGAGAATCTCAGTGCAAAGAGGTCACGTATAGAACAGAAGGAAGAGCTGGATGATGTCATAGCATTAGATTGAACAGAAATGCCTCTAAACAGAGCCCTCTTACTACTTAGTTTATCTAGGCAGAACCAGATTATTTGTTATGTCCTTTGTTCCAAAGGGGAAAAAATGGACACCAGTGACTTGAAAATGATTCTGCTCCCTCTGAAAGCATTCATTTTGCTAGAACTGTTAGACACACTGCAGTATGCTATACTGAAAGTAGGAATATAGCTTTAAAAACCCTTTGAACAAAGTATGTGCATAACCAGTCATGAGATAAAACAACACAATGCATGTTGCCTTTTTAATGTAAATACCCTTAGGTATCATTAACAGTTTCAAAATATTGTGGTTAAGTTGATACCTGGTTATAAATATCATGCCTTTATTTTTGGCTAGAAAAATTAATTTTAGCCTAGCTCTAACCATTTTCATACTCTGACTGAAACAGATTCAAAGAAGTATCAAATGCTATGTATTGAAACTTGTTTTTAAATGTTAAATGGCACTATGTATATTAATGTAAAACAATGTTAATTTACTCACGTTTTCAGTTTGTACTGCCTGGTATGTCTGTGTATGAAGCCAATTTTTGTGTATTGTTATAGTTTCAGGTTATTTATAGTTGATGTTTTGTAAAACTCAATGGCTATACTTATGGACCAAATAAATGGCATCTGCATTCTTGTTACAA
>NM_005499.3
gcggctcggttctcccgcctccgcctccgccGCGGCTCGTGGTTGTCCCGCCATGGCACTGTCgcgggggctgccccgggagctggctgaggcggtggccgggggccgggtgctggtggtgggggcgggcggcATCGGCTGCGAGCTCCTCAAGAATCTCGTGCTCACCGGTTTCTCCCACATCGACCTGATTGATCTGGATACTATTGATGTAAGCAACCTCAACAGACAGTTTTTGTTTCAAAAGAAACATGTTGGAAGATCAAAGGCACAGGTTGCCAAGGAAAGTGTACTGCAGTTTTACCCGAAAGCTAATATCGTTGCCTACCATGACAGCATCATGAACCCTGACTATAATGTGGAATTTTTCCGACAGTTTATACTGGTTATGAATGCTTTAGATAACAGAGCTGCCCGAAACCATGTTAATAGAATGTGCCTGGCAGCTGATGTTCCTCTTATTGAAAGTGGAACAGCTGGGTATCTTGGACAAGTAACTACTATCAAAAAGGGTGTGACCGAGTGTTATGAGTGTCATCCTAAGCCGACCCAGAGAACCTTTCCTGGCTGTACAATTCGTAACACACCTTCAGAACCTATACATTGCATCGTTTGGGCAAAGTACTTGTTCAACCAGTTGTTTGGGGAAGAAGATGCTGATCAAGAAGTATCTCCTGACAGAGCTGACCCTGAAGCTGCCTGGGAACCAACGGAAGCCGAAGCCAGAGCTAGAGCATCTAATGAAGATGGTGACATTAAACGTATTTCTACTAAGGAATGGGCTAAATCAACTGGATATGATCCAGTTAAACTTTTTACCAAGCTTTTTAAAGATGACATCAGGTATCTGTTGACAATGGACAAACTATGGCGGAAAAGGAAACCTCCAGTTCCGTTGGACTGGGCTGAAGTACAAAGTCAAGGAGAAGAAACGAATGCATCAGATCAACAGAATGAACCCCAGTTAGGCCTGAAAGACCAGCAGGTTCTAGATGTAAAGAGCTATGCACGTCTTTTTTCAAAGAGCATCGAGACTTTGAGAGTTCATTTAGCAGAAAAGGGGGATGGAGCTGAGCTCATATGGGATAAGGATGACCCATCTGCAATGGATTTTGTCACCTCTGCTGCAAACCTCAGGATGCATATTTTCAGTATGAATATGAAGAGTAGATTTGATATCAAATCAATGGCAGGGAACATTATTCCTGCTATTGCTACTACTAATGCAGTAATTGCTGGGTTGATAGTATTGGAAGGATTGAAGATTTTATCAGGAAAAATAGACCAGTGCAGAACAATTTTTTTGAATAAACAACCAAACCCAAGAAAGAAGCTTCTTGTGCCTTGTGCACTGGATCCTCCCAACCCCAATTGTTATGTATGTGCCAGCAAGCCAGAGGTGACTGTGCGGCTGAATGTCCATAAAGTGACTGTTCTCACCTTACAAGACAAGATAGTGAAAGAAAAATTTGCTATGGTAGCACCAGATGTCCAAATTGAAGATGGGAAAGGAACAATCCTAATATCTTCCGAAGAGGGAGAGACGGAAGCTAATAATCACAAGAAGTTGTCAGAATTTGGAATTAGAAATGGCAGCCGGCTTCAAGCAGATGACTTCCTCCAGGACTATACTTTATTGATCAACATCCTTCATAGTGAAGACCTAGGAAAGGACGTTGAATTTGAAGTTGTTGGTGATGCCCCGGAAAAAGTGGGGCCCAAACAAGCTGAAGATGCTGCCAAAAGCATAACCAATGGCAGTGATGATGGAGCTCAGCCCTCCACCTCCACAGCTCAAGAGCAAGATGACGTTCTCATAGTTGATTCAGATGAAGAAGATTCTTCAAATAATGCCGACGTCAGTGAAGAAGAGAGAAGCCGCAAGAGGAAATTAGATGAGAAAGAGAATCTCAGTGCAAAGAGGTCACGTATAGAACAGAAGGAAGAGCTTGATGATGTCATAGCATTAGATTGAACAGAAATGCCTCTAAACAGAACCCTCTTACTATTTAGTTTATCTGGGCAGAACCAGATTGTTATGTCCTTTGTTCCAAAGGGAAAAAATTGACAGCAGTGACTTGAAAATGATTCTGCTCCCTTTGAAAGCATTCATTTTGCTAGAACTGTTAGACACATTGCAGTATGCTGTATTGAAAGTAGGAATATAGTTTTAAAAACCCTTTGAACAAAGTGTGTGCATAACCAGTCATGAGATAAAACAACACAATGCATGTTGCCTTTTTAATGTAAATACCCGTAGGTATCATTAATAGTTTCAAAATATTGTGGTTTAGTAAAGTTGATACCTGGTTATAAATATTATGCCTTTATTTTTGGCTAGAAGAAGAATTATTTTTAGCCTAGATCTAACCATTTTCATACTCTTAACTGATTGAAACAGATTCAAAGAAGTATCGAGTGCTATGCATTGAAACTTGTTTTTAAATGTTAGATGGCACTATGTATATTAATGTAAAACAATGTTAATTTACTCAAGTTTTCAGTTTGTACCGCCTGGTATGTCTGTGTAAGAAGCCAATTTTTGTGTATTGTTACAGTTTCAGGTTATTTATATTCGATGTTTTGTAAAACTCAAATAACGACTATACTTATGGACCAAATAAATGGCATCTGCATTCTTGTTACACATGCCTGCACAGTTCCTGTTTCTGCTGCCTTATATCTACTGCAGGAATGTCAAATTCTTTTCATTAAAAAAAGAACTCggtcgggcacggtggctcatgcctgtaatcccagcactttggaaggctgaggcaggtggatcacctgaggtcagtagttcaagaccaacctggtcaacatggtgaaaccccatctctactaaaaaaaaaaaaaaaaattagccgggcctggtggcaggcacctgtaattccagctactcaggaggctaaggcagcagaattgcttgaacccgggaggcagaggttgcagtgagccaagattgtgctattgctactccagccagggcgatgagtgaaactccatctcaaaaaaGGTTCAGAAGATCTCCACTGTTTGCCAAAGACGAGTACTTTCTTTTCTTTATTCTTGGAGACTTCACATGTAGGAAGAGTACTTTCTAAAATAAAGCTCTTCCTGCGTGTGgtggtggtgcacatctgtgttccagctactcaggaggctgaggcaggaggatggctggagcccagaagttcaaggccagcctgggtaacatagcaagaccctgtctctaaaaaataagtaaaTAAAATAAAGCTTTTAATGGCAGTGGGttttttgttcgtttttgagatgaagcctcacactgtcatctggcctggagtgcagtggcgcgatcctggctcactgcagcctccgccttccaggtgcaagcgattctcctgtctcagcctcccctgtagctgggattacaggcgccctccaccacgctcagctaattttttgtatttttagtagagatggggtttcactatgttggccaggctggtctggaactcctgacctcgtgatccacctgcctcagcctcccaaagtgctgggattacaggcgtgagccactgcgcctggccTAATGGCAGTGTTTTTAAAATTTGGATTGTCAGCAGTTGGCCTTTGTTGAGAAAATGTGTGACTTTGCCCAAGCCCAGTAACTTGGAGCCTTGAATTTGAGATGCTGGAAAGGGAGTCCTTCCTCCTTTCTGCAGTGTTTGTCTGGGTTGTCCCCTAGTTTACCAAAGTCCATTTTGAATGTACCATCCCCAGCCCAACTCCAGCCTACAGATAGTGCCAGACCGCCAGTAGGTGGAGTAGCACTGTCTTCCTGGTCCCGGACCTCAGAGGGCTTTGCCTGTTAGGGTACTCTTATCACTCAGAGATGGGCCTTGAGTTTTCAGAGAACAGAAAGCCATTAAGCTGTTTCCCCTATTGTATTCATGTGCCCTTTGTGTTTCTGGCAATAATTTATTTTATATTTCAACTAAATTTTAAATTTCTAATTCA

Publications

PMID - Link Title
No publications available for this retrocopy