Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Summary

Retrocopy Name IFTAPP1
Wait
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:89289592-89290362  UCSC
Coordinates (T2T) chr1:89132948-89133718  UCSC
Coordinates (hg19) chr1:89755275-89756045  UCSC
Strand -
Parental Sequence NM_001276722.2
Parental seq. overlap 696 bp
Parental seq. overlap (%) 67.2%
Genomic Region Intergenic
Retrocopy Summary IFTAPP1, located on chr1:89289592-89290362, is a retrocopy of the parental gene IFTAP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name IFTAP
Full Name intraflagellar transport associated protein
Also known as C11orf74|HEPIS|NWC
Coordinate chr11:36594246-36659272
Strand +
Gene summary This gene encodes a protein that was identified as a cellular interacting partner of non-structural protein 10 of the severe acute respiratory syndrome coronavirus (SARS-CoV). The encoded protein may function as a negative regulator of transcription. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes C11H11orf74P1
Bonobo Pan paniscus IFTAPP1
Gorilla Gorilla gorilla C11H11orf74P1
Orangutan Pongo abelii C11H11orf74P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Related Sequence

>IFTAPP1
ACTGTGGCCTCGTGAATAGGAATGTGGGCTCATACATCAGGATTGAAAATAATGCATGAAGATCAATTAATCAAAGAAGTCCTGGATAAATTCCTTAATTGTCATGAGCAAACATATGATGAAGAATTTCTGAACACTTTTACTCATCTTTCACAAGAGGATCTTGTGTCCAAAAGGGGAGTGTTTGGAACTGATTCTTCGGAAAACATTTTTACCTAAGCAAAAGTTACTCATAAAAATGAAGCTAATGACTACCATCTTAGAAATAAAACCATTTTTCTTCGTACTTCATCACAATGTTTGGAAGAACAGGTAGACAATTTCCTAGATTTGGAAGATTTGGACATGGATGAAGAGAATAAACCCCAAAAAAGTGAGGATTTGCTGCTGCTCCCAGGAGAAGTGGAGTAGGATGTAAGCACCAGCATTCCTTCCTGTATCCTTCTGTGGCCCAGCCTCCCACCTGTGAAGTGAAGCCAAAGCCTACTGTAAAAAGAATGGACAAACAGATGGAAGAGATATGTGGAGATGAAGCTCAACCCTTCTCACTTGATGAGGAATTTGATTATGACAATGTGACGCTAACCTCCAAGTTTAGTCCTGCAGAGACAGAGACCATCAAAGAGCTAGGCAAGCAGAAGAGAAAGGACACCAGCCCAGACTTACAGGAACCCTGTGACTGATTCACAGAGGCATTTTTTTGTGTGTTTATTTTAATTTTGTTCTTATTCAAGTAACATTAG
>NM_001276722.2
CTCTCTGGGATGTGTAGCTTTGGAAATCTGTCTTTGTTGCTCTGGGAGAGGGGACTCCTGGAATGTGTCTGTGAATAAAGACTAGCCGAAGGTGCGAAGTGACTAGACGGGAGCAAAGGAGGAAAACTAGGGAATGGGAGGTGAGAGTGGCTGACACCGACCCAACGTCCGGGTTGCCGGAAGGCTGCAGCGCCCGGAGCGGTGTCGGGCAAACCGCTACCCTGGTATTGCTGGAGCCTCTCCTGGGGACTTTTGAACAGATACTGTGGCCTCATGAATAGGAATGTCTGCCCATATGTCAGGATTGGAAATAATGGATGAAGATCAATTAATCAAAGACGTCTTGGATAAATTCCTTAATTGTCATGAGCAAACATATGATGAAGAATTTCTGAACACTTTTACTCATCTTTCACAAGAGGATCATGTGTCCAAAAGGGGAGTGTTTGGAACTGATTCTTCAGAAAACATTTTTACCTCAGCAAAAGTTACTCATAAAAATGAAGCAGATGACTACCATCTTAGAAATAAAACCATCTTTCTTCGTACTTCATCACAATGTTTGGAAGAACAGGTAGATAATTTCCTAGATTTAGAAGATTTGGACATGGATGAAGAGATTAAACCCCAAATGAGTGAGGATTTGCTGCTGCTTCCAGGAGAAGTGGAGCAGGATGTAAGCACCAGCATTCCTTCCTGTATCCCTTTTGTGGCCCAGCCTCCTACCTGTGAAGTGAAGCCAAAGCCCAGTGTTAAAAGAATGGACAAACAGACGGAAGAGATACTTGGAGATGAAGTTCAACTTTTTTCACTTGATGAAGAATTTGATTATGACAATGTGATGCTAACCTCCAAGTTTAGTCCTGCAGAGATAGAGAACATCAAAGAGCTATGCAAGCAGCAGAAGAGAAAGGACACCAGCCCAGACTTAGAGAAATCCTGTGACTGATTCACAGAGGCATTTTGTGTGTGTGTGCTTATTTTAATTTTGTTCTTATTCTAGCAACATTAGAATAAAAGATAAACCTACTATAA

Publications

PMID - Link Title
No publications available for this retrocopy