Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name CHCHD10P2
Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr22). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr19:10216988-10217320  UCSC
Coordinates (T2T) chr19:10343124-10343456  UCSC
Coordinates (hg19) chr19:10327664-10327996  UCSC
Strand -
Parental Sequence NM_213720.3
Parental seq. overlap 303 bp
Parental seq. overlap (%) 43%
Genomic Region Intergenic
Retrocopy Summary CHCHD10P2, located on chr19:10216988-10217320, is a retrocopy of the parental gene CHCHD10. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CHCHD10
Full Name coiled-coil-helix-coiled-coil-helix domain containing 10
Also known as C22orf16|FTDALS2|IMMD|MIX17A|N27C7-4|SMAJ
Coordinate chr22:23765834-23767972
Strand -
Gene summary This gene encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19. [provided by RefSeq, Aug 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CHCHD10P2
Bonobo Pan paniscus CHCHD10P2
Gorilla Gorilla gorilla CHCHD10P2
Orangutan Pongo abelii CHCHD10P2
Gibbon Nomascus leucogenys CHCHD10P1
Green monkey Chlorocebus sabaeus CHCHD10P1
Crab-eating macaque Macaca fascicularis CHCHD10P2
Rhesus Macaca mulatta CHCHD10P2
Baboon Papio anubis CHCHD10P2
Golden snub-nosed monkey Rhinopithecus roxellana CHCHD10P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CHCHD10P2
GCTGCCTCCCAGCCCCTACAGATGGGGCTCTGCACCTACAAGATCAGGCAGTTCCTGGACTGTTCGACCACTGAGAATGACCTGTCCCTGTGTGAGGGCTTCAATGAGGCCCCAAAGCAGTGCAAGTACAACCATGGTCTGAGCTCCCTGCCTTGAAGACGTTGGTGCAGACTCGAGGGCCAGCTCTGCACCCACCTGTACCCCTTGCCCACAGCCAGACCACAACACCAGATTGTACCTGGATAGCTGGGATTGGAAGTGAGGAATAGGTTTCTCACCCCACAGATAACCCAAGACACAAATGTGCAATTAAAAAATTTATTTTAGACCACc
>NM_213720.3
CTTTTTTGCGCCGGCTGTGACAAGCGCTGCGGCATTTGTCCCCGCGACAGCACCGCTGCCGCCGTCTCTAAGGTCGCCCGGGTCCCACCGCCGCCACCATGCCTCGGGGAAGCCGCAGCGCGGCCTCCCGGCCAGCCAGCCGCCCAGCCGCGCCCTCTGCCCACCCGCCCGCGCACCCACCGCCCTCGGCAGCCGCCCCAGCCCCCGCCCCTTCGGGCCAGCCGGGGCTCATGGCTCAGATGGCGACCACGGCCGCAGGGGTAGCCGTGGGCTCGGCTGTGGGACACGTCATGGGCAGCGCCCTGACCGGAGCCTTCAGCGGGGGGAGCTCGGAGCCCTCCCAGCCTGCTGTCCAGCAGGCCCCCACCCCCGCTGCCCCCCAGCCCCTGCAGATGGGGCCCTGCGCCTACGAGATCAGGCAGTTCCTGGACTGTTCCACCACTCAGAGTGACCTGTCCCTGTGTGAGGGCTTCAGCGAGGCCCTGAAGCAGTGCAAGTACTACCATGGTCTGAGCTCCCTGCCCTGAAGAGGTCGGTGCAGACTCGGGGGCCAGTCCTGCACCCACCTCTACCCCTCGCCGACAGCCAGACCACAACACCAGATTGTACCCAGATAGCTGGGATTGGAAGTGAGGAGGTTTCTCACCCCACAGATAACCCAAGACACAAATGTGCAATTAAAAGTTTATTTTAGACCACA

Publications

PMID - Link Title