Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name STAU1P1
Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr19:15513018-15516838  UCSC
Coordinates (T2T) chr19:15638045-15641869  UCSC
Coordinates (hg19) chr19:15623829-15627649  UCSC
Strand -
Parental Sequence NM_001319134.2
Parental seq. overlap 887 bp
Parental seq. overlap (%) 22%
Genomic Region Intragenic (CYP4F22)
Retrocopy Summary STAU1P1, located on chr19:15513018-15516838, is a retrocopy of the parental gene STAU1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name STAU1
Full Name staufen double-stranded RNA binding protein 1
Also known as PPP1R150|STAU
Coordinate chr20:49113339-49219295
Strand -
Gene summary Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. [provided by RefSeq, Apr 2020]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes STAU1P1
Bonobo Pan paniscus STAU1P1
Gorilla Gorilla gorilla STAU1P1
Orangutan Pongo abelii STAU1P1
Gibbon Nomascus leucogenys STAU1P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>STAU1P1
GTGTGTGCACTGAGGCTCTGTGTGTGGTCCATATGGAAAGCCTGGTACCCCTGCGAGTTAAGTACTGCCTCCATTCATCGTTTACACTGGAGTTTTTCTCCTCATGGAATGCGAGTAAAACTTAGTGTTTGTCACCAATAAATGGTAATACAGACACTATATAAAATTTTCATTTGAGAGTTTCTCAACTGTATCTAATTATATCGCACAGTTTGGAAACTTTTCTGAGACTGACTTTATCAATAATCTAACCGACAAAGATCATATCCACGTGTATGTAGTTAGACATTTTTATTTCATTGACTAACCCAGCACCATTTCAGTGATGCAAATTACGTGCCCTATGGTTCAGCTGAAACAGTCCTGGACTTTCAAAAACCTTGAATAAGTCTCCCACAGTTGTATAAATTGGACAATTTAGGAATTTTAAACTTTAGATGATCATTTGCTTCCATTTTTATTTTATTTTTATTTTTGTTAATGCAAACAGGACTTAAACAAATGAACTTTGATCTCCATTTTAAATATTCTTTAAGAAAATCATGTGTCTATACATACGGCTCTTGAGGACTTAGCTTTCACTACACTACAGGATATGATCTCCACATAGTTCACATAAAACTGCAGACTGATTTTCCAGAGTGCTCGATACTATTAATTACATCTCGATTAGGGCTGAAAAGTATGACCTATGTTTCTTTATACAGTTGTGTTGCTTTTGATGTTGTGTTACTATACACAGAAGTGTGTGCACTGGTTTGTTGTGACGGCCACTCGGTGACCTGGCTGTCCCTACGCAATACCAGCTGCCTTTGGGGAAGAAGGGCTGCCCAGCCAGCTGGCTCTCCTGGGGCACCAGCAGATCCACGCCCTGGGCACCTTCCTGTTTGGTCTTTTTTTTCCCGTGTGAAAGAAGAAACTGAAAGCATGACCCCTTCTCAAGCTGGCTTAGTTGGGACAAACCCTGGACAGCCACACCAGAGAGAGGCCTTCAACCAGCCCCAGAGCTAAAAGCACCAGAGAAAGTCAAATGCTTCCTATTCAGCATGACCTAACTTCTAGTGTGCCACGGCCCCACCACTTCCTGCAGTGCCCACACCATCACCACTGCTTTCTCTTCCAACAGTGATCTGTATTCTTAGTTTCATTATTTCCTTTTTATTGGTATGACACTATATAAAATTAGCTGCACTGAACACCTTAAAGTTGCTGTCTGAGTTGGACCAACAAAGTACAGAGATGCCAAGAACAGGAAATGGATCAATGTCTGTGTGTGGGAGGTGCTGAACCTTTTCTGGCCATGAACCATTATAAAATCCCAACATATACACTGAAAATATTAAAACTGCTTTGAAAATTTGGAATTTCTGATACCTCTAGTGGGCCGAGAGACGGTGGGTAAAGGATGTGGGCAGCAGCAGGGAACACAACAGGGGAGGTCAAGGATGTTGAGTCCTGCTATGATATGGCTGCACTAAACATCCATCTCTTCAGGCCACGTACCCCATGGACCTCTCATGAGATCCTCTGAGCAAGTGGACTATCTTTCCAGAGTCCAGGGATTCCAGGTTGAATACAAAGACTTCCCCAAAAACAACAAGAATGAATTTGTATCTCTTATCCATTGCTCCTCTCAGCCGCCTCTGATCAGCCATAG
>NM_001319134.2
CTTCAGCGTTTGCGCCGGCGGCTGCCGCGTCTCTCTCGGCTCCCGCTTCCTTTGACCGCCTCCCCCCCCCGGCCCGGCGGCGCccgcctcctccacggccactccgcctcttccctcccttcgtcccttcttcctctcccttttttccttcttccttcccctcctcGCCGCCACCGCCCAGGACCGCCGGCCGGGGGACGAGCTCGGAGCAGCAGCCAGAGTTTATTAACCACTTAACCTCTCAGAACTGAACAAAGACAACATTGTTCCTGGAACGCCCTCTTTTTAAAAAAGAAAGCATAACCCCTACTGTAGAACTAAATGCACTGTGCATGAAACTTGGAAAAAAACCAATGTATAAGCCTGTTGACCCTTACTCTCGGATGCAGTCCACCTATAACTACAACATGAGAGGAGGTGCTTATCCCCCGAGGTACTTTTACCCATTTCCAGTTCCACCTTTACTTTATCAAGTGGAACTTTCTGTGGGAGGACAGCAATTTAATGGCAAAGGAAAGACAAGACAGGCTGCGAAACACGATGCTGCTGCCAAAGCGTTGAGGATCCTGCAGAATGAGCCCCTGCCAGAGAGGCTGGAGGTGAATGGAAGAGAATCCGAAGAAGAAAATCTCAATAAATCTGAAATAAGTCAAGTGTTTGAGATTGCACTTAAACGGAACTTGCCTGTGAATTTCGAGTCTTTCCCTCTGAAACAGGTGGCCCGGGAGAGTGGCCCACCCCACATGAAGAACTTTGTGACCAAGGTTTCGGTTGGGGAGTTTGTGGGGGAAGGTGAAGGGAAAAGCAAGAAGATTTCAAAGAAAAATGCCGCCATAGCTGTTCTTGAGGAGCTGAAGAAGTTACCGCCCCTGCCTGCAGTTGAACGAGTAAAGCCTAGAATCAAAAAGAAAACAAAACCCATAGTCAAGCCACAGACAAGCCCAGAATATGGCCAGGGGATCAATCCGATTAGCCGACTGGCCCAGATCCAGCAGGCAAAAAAGGAGAAGGAGCCAGAGTACACGCTCCTCACAGAGCGAGGCCTCCCGCGCCGCAGGGAGTTTGTGATGCAGGTGAAGGTTGGAAACCACACTGCAGAAGGAACGGGCACCAACAAGAAGGTGGCCAAGCGCAATGCAGCCGAGAACATGCTGGAGATCCTTGGTTTCAAAGTCCCGCAGGCGCAGCCCACCAAACCCGCACTCAAGTCAGAGGAGAAGACACCCATAAAGAAACCAGGGGATGGAAGAAAAGTAACCTTTTTTGAACCTGGCTCTGGGGATGAAAATGGGACTAGTAATAAAGAGGATGAGTTCAGGATGCCTTATCTAAGTCATCAGCAGCTGCCTGCTGGAATTCTTCCCATGGTGCCCGAGGTCGCCCAGGCTGTAGGAGTTAGTCAAGGACATCACACCAAAGATTTTACCAGGGCAGCTCCGAATCCTGCCAAGGCCACGGTAACTGCCATGATAGCCCGAGAGTTGTTGTATGGGGGCACCTCGCCCACAGCCGAGACCATTTTAAAGAATAACATCTCTTCAGGCCACGTACCCCATGGACCTCTCACGAGACCCTCTGAGCAACTGGACTATCTTTCCAGAGTCCAGGGATTCCAGGTTGAATACAAAGACTTCCCCAAAAACAACAAGAACGAATTTGTATCTCTTATCAATTGCTCCTCTCAGCCACCTCTGATCAGCCATGGTATCGGCAAGGATGTGGAGTCCTGCCATGATATGGCTGCGCTGAACATCTTAAAGTTGCTGTCTGAGTTGGACCAACAAAGTACAGAGATGCCAAGAACAGGAAACGGACCAATGTCTGTGTGTGGGAGGTGCTGAACCTTTTCTGGCCATGAACCATTATAAAATCCCAACATATATACTGAAAATACTGAAACTGCTTTGAAAATTTGGAATTTCTGATACCTCCAGTGGGCCGAGAGACACGGTGGGTAAAGGATGTGGGCAGCAGCAGGGAAGACAACAGAAACACAAGGAGGCggctgtggccgggctggactgtgctgggGTTTGTTGTGATGGCCACTCGGTGACCTGGCGGTCCCTACGCAATAGCAGCTGCCTGTGGGGAAGAAGGGCTGCCCAGCCAGCTGGTTCTCCCGGGACACCAGCAGATCCACACCCTGGGCACCTCCGTGTTTGGTCTTTTTTTTCCCCTGTGTGAAAGAAGAAACGGCACGACCCCTTCTCAAGCTGGCTCACTCAGACACATTGGGACAAACCCTGGACAGCCATGCCAGAGAGAGGCCTTTGACCGGCCCCAGAGCTAAAAGCACCAGAGAAAATCAAATGCTTCCTACTCAGCGTGACCCAACTTTTCTAGTGTGCCACGGCCCCACCACCTCCTGCAGTACCCACACCATCACCACTGCTTTCTCTTCCAACAGTGATCTGTATTCTTAGTTTCATTATTTTCTTTTGATTGATATGACACTATATAAAATTTTCATTTGAGAATTTCTCAATTGTATCTAGTTAAATAGCACAGTTTGGAAACTTGTCTGAGACTGACTTTATCAATAATCTAACCGACAAAGATCATATCCATGTGTATGTGGTTAGACATTTTTATTTCATTGACTAACCCAGGACAGTTTCAGTGATGCAAATTGTGTGCCCTCTGGTTCAGCTGAAACAGTCCTGGACTTTCAAAAACCTTGAATAAGTCTCCCACAGTTGTATAAATTGGACAATTTAGGAATTTTAAACTTTAGATGATCATTTGGTTCCATTTTTATTTCATTTTTATTTTTGTTAATGCAAACAGGACTTAAATGAACTTTGATCTCTGTTTTAAAGATTATTAAAAAACATTGTGTATCTATACATATGGCTCTTGAGGACTTAGCTTTCACTACACTACAGGATATGATCTCCATGTAGTCCATATAAACCTGCAGAGTGATTTTCCAGAGTGCTCGATACTGTTAATTACATCTCCATTAGGGCTGAAAAGAATGACCTACgtttctgtatacagctgtgttgcttttgatgttgtgttactgtACACAGAAGTGTGTGCACTGAGGCTCTGCGTGTGGTCCGTATGGAAAGCCTGGTAGCCCTGCGAGTTAAGTACTGCTTCCATTCATTGTTTACGCTGGAATTTTTCTCCCCATGGAATGTAAGTAAAACTTAAGTGTTTGTCATCAATAAATGGTAATACTAAATTTTTTTGTTAATTTATTCTCAAATGCCACTACTGCTAGGTTGGTCCCCTCCCAACTTGCCCCTATCCTTTTTTTATTTTTAAGAAAAAAACTTTGTAATGCTTGTGATTCCATCTGGGCAAAAGTCTGAAGATCTGAAATAACTTTATATCAAACCATTGATCAATAAACAGCTACTAATGAA

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