Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PCGF7P
Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr19:22137927-22140092  UCSC
Coordinates (T2T) chr19:22276322-22278487  UCSC
Coordinates (hg19) chr19:22320729-22322894  UCSC
Strand +
Parental Sequence NM_001011663.2
Parental seq. overlap 2008 bp
Parental seq. overlap (%) 89.7%
Genomic Region Intergenic
Retrocopy Summary PCGF7P, located on chr19:22137927-22140092, is a retrocopy of the parental gene PCGF6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PCGF6
Full Name polycomb group ring finger 6
Also known as MBLR|RNF134
Coordinate chr10:103302796-103351140
Strand -
Gene summary The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PCGF6P1
Bonobo Pan paniscus PCGF6P1
Gorilla Gorilla gorilla PCGF6P1
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PCGF7P
AACCATGGAGGGGGTCGCGGTGGTGACGGCGGGCAGCGTAAGCGCTGCCAAAGCCGAGGGAGCTGCAGCCTTGAGCGGGTGAGGAGGGACCGGCGCCTCTGTCTGAGACTGGGGCTCCCGGCTGCTCCGGCTCCCGGCCCCCTGAGCTGGAGCCAGAGCGCAGCCTGGGCCGCTTCAGAGGCCGCTTCaCATGAGTCACTTCTCGTTGAGGCTGGAGGGAGGCCGGCAAGACTCGGAGGACGAGGAGGAGCGCCTGATTAATCTCTCTGAGCTGACCCCATATATCTTGTGTTCCATTTGCAAAGGTTACTTAATAGATGCAACTACCATCACAGAATATCTTTATACCTTTTGTAAAAGCTGCGTCGTAAGACATTTTTACTACAGCAACAGATGTCCAAAATGCAATATAGCAGTACATCAGACACAACCTCTTTATAAGGTTGGACCGACAGTTACAAGACATAGTGTACAAATTAGTGATCAATCTAGAGGAAAGAGAAAAAAAGCAAATGCATGATTTCTATCAAGAAAGAGGTCTAGAAGTACCTAAACCTGCTGTTCCACAGCCAGTCCCTTCAAGCAAAGGAAGATCTAAAAAAATCCGAGAATCAGTGTTTCCTATTCCACCTGAACTTGATATGTCTTTATTACTGGAGTTCATTGGTGCTAATGAAGGCACGGGACATTTTAAGCCATTGGAAAAGAAGTTTGTTCGAGTTTCAGGAGAAGCAACTATTGGACATGTAGAAAAATTCTTCAGAAGAAAAATGGGTCTTGATCCAGCTTGTCAGGTAGATATCATCTGTGGTGATCACCTGTTGGAGCAGTATCAAACTCTAAGGGAAATCCGACGTGCAATAGGTGATGCAGCAATGCAGGATGGTCTGCTTGTCCTTCATTATGGTCTTGTAGTTTCTCCTCTGAAGATAACTTGAAGATTCTAGGCACATTATGAGGAGGGAAACAAAGGAGGCTTCTGCAGGACTGCATCTCACCAAAGATTTCCATGAAATGTAATTGCTACCACTTTGCTGTTCAAGACATAACTTACCTATTTTTAGCACCAAGAATTATAGCATTTATAAGTACAACTTGGAACGATGGAATGCATCTGTTACTAGAGACTGTATATAAAAAGCAGCGAAAGCTCAGGGGAAATTTTTCAAAAATTGAATTTTAAAATTTCTTATGATTTTAAATACCTTGACATTGATTTTGCTTCCCATCTTTGAAGTAATTGGTTAGTTTTCTTTGTTCAGCCATTTCAAGTTGGTGGTTGGGATATCTGCTCTCTGGGATGGCATCAGTTGGGCAGTCATCCTTTTGGAAGAGAAGTGTGCTTTTGAATGGAAGATCCAAAGCCAGTCTTTGTTAAACTGCAGGGCGTACTCTCAAAGACCAAAACTATTGGCCACTTTTGTATGTTGCCAGCATATTTTGAACTTGTATCTTTTTTTATACTAGCAACACTACAAAGGAGAAGTTACTCATTTCAAAATGGATGAATTGTTATTATGTGTGAAGAGACTCTGAGTTTATGGTCTGTGCCATAAACTTTCAGTGTAATAAGACTTCTTCAATACATCTTCCAATAAGGGGTGCTTCTTTGTGACAGTATTTTTATTTCTGACATTCATTTTATTTGGGTACATAGTGTGGTTGTTGATACCTTGCAAAAGTATTGCTTCTGAAAGTAATAAAAAATTTTAGGAGAATTTGAGAAGTTTACAGAATTACTTATTCATTGTTTTCTTGGTAAGTCAGTTTAATGTTTATTTTTCTCATTATTTCATCACTGGAATAAAGAATAAGGGTGTTTGAGCTCACCTCCATGCAAAGACTTCAGTTTTAAAACATTATTTTGCCTAAAATTAGCATTGTGATGCTCTCTAAAAGAAATATTTTATAAACCCTGTTCACAGCAGAATTTCTGAATCTGTATAGAGACTACTACAAAATTGGACAAAGATTGGCAATTCTTTGTAAAGAATTTGTGAACTGTGTATAAATTTATTCTAACATTTAATAAAAATGTATTTAAACCTA
>NM_001011663.2
AGTGGTGGCGTCCGAGGCCGGCCGAACTCCCGCGCTCTCCCGCCGCCTCGCCTCGCCTGGTGTCTCTCCCGACCATGGAGGGGGTCGCGGTGGTGACGGCGGGCAGCGTAGGCGCTGCCAAAACCGAGGGAGCTGCAGCCTTGCCGCCTCCGCCTCCTGTCTCCCCGCCCGCCCTCACCCCTGCACCCGCAGCGGGTGAGGAGGGACCGGCGCCTCTGTCTGAGACGGGGGCTCCCGGCTGCTCCGGCTCCCGGCCCcctgagctggagccggagcgcagcctgggccgCTTCAGAGGCCGCTTCgaggacgaggacgaggagttggaagaagaagaggagctggaggaggaagaagaggaggaggaggaggaCATGAGTCACTTCTCGTTGAGGCTGGAGGGAGGCCGGCAGGACTCGGAGGACGAGGAGGAGCGCCTGATTAATCTCTCTGAGCTGACCCCATACATCTTGTGTTCCATTTGCAAAGGTTACTTAATAGATGCAACTACCATCACAGAATGTCTTCATACCTTTTGTAAAAGCTGCATCGTAAGACATTTTTACTACAGCAACAGATGTCCAAAATGCAATATAGTAGTACATCAGACACAACCTCTTTATAACATAAGGTTGGACCGACAGTTACAAGACATAGTGTACAAATTAGTGATCAATCTAGAGGAAAGAGAAAAAAAGCAAATGCATGATTTCTATAAAGAAAGAGGTCTAGAAGTACCTAAACCTGCTGTTCCACAGCCAGTCCCTTCAAGCAAAGGAAGATCTAAAAAAGTCCTAGAATCAGTGTTTCGTATTCCACCTGAACTTGATATGTCTTTATTACTGGAGTTCATTGGTGCTAATGAAGGCACGGGACATTTTAAGCCATTGGAAAAGAAGTTTGTTCGAGTTTCAGGAGAAGCAACTATTGGACATGTAGAAAAATTCCTCAGAAGAAAAATGGGTCTTGATCCAGCTTGTCAGGTAGATATAATCTGTGGTGATCACCTGTTGGAGCAGTATCAAACTCTAAGGGAAATCCGACGTGCAATAGGTGATGCAGCAATGCAGGATGGTCTGCTTGTCCTTCATTATGGTCTTGTGGTTTCTCCTCTGAAGATAACTTGAAGATTCTAGGCACATTATGAGGAGGGAAACAAAGGAGGCTTCTGCAGGACTGCATCTCACCAAAGATTTCCATGAAATGTAATTGCTACCACTTTGCTGTTCAAGACATAACTTACCTATTTTTAGCACCAAGAATTATAGCGTTTATAAGTACAACTTGGAACGATGGAATGCATCTGTTACTAGAGACTGTATATAAAAAGCAGCCAAAGCTCAGGGGAAATTTTTCAAAAATTGAATTTTAAAATTTCTTATGATTTTAAATACCTTGACATTGATTTTGCTTCCCATCTTTGAAGTAATTGGTTAGTTTTCTTTGTTCAGCCATTTCAAGTTGGTGGTTGGGATATCTGCTCTCTGGGATGGCATCAGTTGGGCAGTCATCTTTTTGGAAGAGAAGTGTGCTTTTGAGTGGAAGATTCAAAGCCAGTCTTTGTTAAACTGCAGGGTGTACTCTCAAAGACCAAAACTATTGGCCACTTTTGTATGTTGCCAGCATATTTTGAACTTGTACCTTTTTTTATACTAGCAACACTACAAAGGAGAAGTTACTCATTTCAAAATGGATGAATTGTTATTATGTGTGAAGAGACTCTGAGTTTATGATCTGTGCCATAAAATTTCAGTGTAATAAGACTTCTTCAATACATCTTCCAATAAGGGGTGCTTCTTTGTGACAGTATTTTTATTTCTGACATTCATTTTATTTGGGTACATAGTGTGGTTGTTGATACCTTGCAATAGTATTGCTTCTGAAAGTAATAAAAAATTTTAGGAGAATTTGAGAAGTTTACAGAATTACTTATTCATTGTTTTCTTAGTAAGTCAGTTTAATGTTTATTTTTCTCATTATTTCATCACTGCAATAAAGAATAAGGGTGTTTGAGCTCACCTCCATGCAAAGACTTCAGTTTTAAAACATTATTTGCCTAAAATTAGCATTGTGATGCTTTCTGAAAGAAATATTTTATAAATCCTGTTTAACAGCAGAATTTCTGAATGTGTAGAGACTACTACAAAATTGGAAAAAGATTGGCAATTCTTTGTAAAGAATTTGTGAATTGTGTATAAATTTATTCTAACATTTAATAAAAATGTATTTTAACCTA

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