Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name IST1P1
Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr19:37791695-37794058  UCSC
Coordinates (T2T) chr19:40593230-40595592  UCSC
Coordinates (hg19) chr19:38282335-38284698  UCSC
Strand +
Parental Sequence NM_001270975.2
Parental seq. overlap 2269 bp
Parental seq. overlap (%) 49.6%
Genomic Region Intergenic
Retrocopy Summary IST1P1, located on chr19:37791695-37794058, is a retrocopy of the parental gene IST1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name IST1
Full Name IST1 factor associated with ESCRT-III
Also known as CHMP8|OLC1
Coordinate chr16:71894408-71931199
Strand +
Gene summary This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes IST1P1
Bonobo Pan paniscus IST1P1
Gorilla Gorilla gorilla IST1P1
Orangutan Pongo abelii IST1P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>IST1P1
GTGGATGGTGAACCCTGATTCTGAAGTCGGTGTCTGCTGTGTTCATGGCAGGATTCGGTTAGGAGGAACAGCACAGCATGCTGGGCTCTGGATTTAAAGCTGAGCACTTAAGAGTGAATTTGAGATTAGTCATAAATCGCCTTGAACTATTGGAGGAAAAAAAAAAAAAACAGAACTGGCCCAGAAAGCAAGGAAGGAGATTGCTGACTATCTGGCTGCTGGGAAAGATGAACGAGCTCGGATCCGTGTGGAGCACATTATCCGGGAAGACTACTTCGTGGAGGCCATGGAGATCCTGGAGCTGTACTGTGATCTGCTGCTGGCTCGGTTTGGCCTTATCCAGTCTATGAAGGAACTAGATTCTGGTCTGGCTGAATCTGTGTCTACATTGATCTGGGCTGCTCCTCGACTCCAGTCAGAAGTGGCTGAGTTGAAAATAGTTGCTGATCAGCTCTGTGCCAAGTATAGCAAGTAATATGGCAAGCTATGTAGGACCAACCAGATTGGAACTGTGAATGACAGGCTAATGCACAATCTGAGTGTGGAAGCCCCATCCAAAATCCTGGTGGAGAGATACCTGATTGAAATTGCGAAGAATTACAATGTACCCTATGAACCTGACTCTGTGGTCATGGCAGAAGCTCCTTCTGGGGTAGAGACAGATCTTATTGATGTTGGATTCACAGATGATGTGAAGAAAGGAGGCCCTGGAAGAGGAGGGGGTGGTGGGTTCACAGCACCAGTTGGTGGACCTGATGGAATGGTGCCAATGCCCATGCCTATGCCCATGCTATCTGCAAATACTCCTTTCTCATATCCACTGCCAAAGGGACCATCAGATTTCAATGGACTGCCAATGGGGACTTACCAGGCCTTTCCCAATATTTATCCATCTCAGATACCAGCAACTCCCCCATCATATGAATCTGTAGATGACATTAATGCTGATAAGAATATCTCTTCTGCACAGATTGTTGGTCCTGGACCCAAGCCAGAAGCCTCTGCAAAGCTTCCTTCCTGACCTGCGGATAACTATGACAACTTTGTCCTACCAGAGTTGCCATCTGTGCCAGACACACTACCAACTGCATTTGCTGGTGCCAGCACCTCAGCATCTGAAGACATTGACTTTGATGATCTTTCCCAGAGGTTTGAAGAGCTGAAAAAGAAAATATAGGTCTCTTAAACCAGGCAACTTTCATATTCTGGGAGTTGAGACTGAGCAATTTCTCCTTGTAACAAAGAATCTCCATGAAATTCCTTTTCATCTGTTAACCGTCACTGAGCACAACACTCCTCCTCTGGGCTCTCTGCCTGCTCCTCCAGATTCTGCTGCTTTCCAGTTCTCTGTTGATCCTGAGACTAACAACCGGAGACTGAGGCTGGAGCAACTGGCTCCTGGCAGCTGTGCTTGTCCCTTTTCTGTCAGAGTGATCCCAGGTTTCCTCCTGGCCCGTCCCATGGTCCCTCCACAGGAGCATAAGAGGATGGGAAAGCACTATGGGGAGACCACCAAAGATGGCTGGACAGTGGGAGAGAGCACGTCGTGAAGCATCCCAGCCTCGTGTTGAGGTTCCAGACTTAGAAACAAACCCCTCTGTACAGGGGGATTGTGGTGAGTGAGAATCAAGGCCACGGTGTGTGTTTTCGCACTCGAATGCAAGTGGGAGAGAGAAAATGACTCAGGACGCCATTGTAACGGTTCCTGGAAGCTGGGCCCTCTCATTGGCATATACACTACTCCTCGCCGCAGGGCACTGTCCCACCGGGATCCAGTTGCAAAGTTTGTCTCGACAGTTTAAGGCCTCGCTTAGTTGTACTGGATTCTCAGGGAGTCCTCTGTGGCCTTTTGCTCTGAGTGCTGTTTCCCTTGTACCAGAGGGCAGCACCATGGAAATTCTGTTTTTCCTGTAGCATATTGTGTTGGATTGCCTTACTGGCAGAGAAAGGACAAATTGCCATTGAAGTCTAGGGTGGGCTTCCAGCTGCCTTAATAGAAGTACTCAAGTCTTTTGGGTAGTGAGCTGGAAAGCCTACAGGAAAAAAGGGGTACCTGTTTTCATTTGAAAACTTTGATTCATGGAAACTTTAAAACTAATCTCAGATAAATTTTTGGTGCAAATGTGGCTGTAGTTGTCCACTGCTTTCCTGGATGGATGGGACTCTTATGTCATAACTTCTATACTCCTTTGGCCCATAGCTAAGGTCATCCTTCCCCACAGGGGTGGCTTTGGGATTGGATTATACAGCTTTTGCTTCTGTGTAGTATACCTGTACATACCTGTTTCAGGAAGCCTTTCTTTAATGTTTTCAGTTGGTTTGTATTCTGTAGCTCAGTAGCTGCTAATAAAGTTAAAGATCCTG
>NM_001270975.2
ATTTTGGATGGTGAACCCTGAAGTCGGTGTCTGCTGCGTTCACGGCAGGATTCGGTTAGGAGGAACAGCACAGCATGCTGGGCTCTGGATTTAAAGCTGAGCGCTTAAGAGTGAATTTGAGATTAGTCATAAATCGCCTTAAACTATTGGAGAAAAAGAAAACGGAACTGGCCCAGAAAGCAAGGAAGGAGATTGCTGACTATCTGGCTGCTGGGAAAGATGAACGAGCTCGGATCCGTGTGGAGCACATTATCCGGGAAGACTACCTCGTGGAGGCCATGGAGATCCTGGAGCTGTACTGTGACCTGCTGCTGGCTCGGTTTGGCCTTATCCAGTCTATGAAGGAACTAGATTCTGGTCTGGCTGAATCTGTGTCTACATTGATCTGGGCTGCTCCTCGACTCCAGTCAGAAGTGGCTGAGTTGAAAATAGTTGCTGATCAGCTCTGTGCCAAGTATAGCAAGGAATATGGCAAGCTATGTAGGACCAACCAGATTGGAACTGTGAATGACAGGCTAATGCACAAGCTGAGTGTGGAAGCCCCACCCAAAATCCTGGTGGAGAGATACCTGATTGAAATTGCAAAGAATTACAACGTACCCTATGAACCTGACTCTGTGGTCATGGCAGAAGCTCCTCCTGGGGTAGAGACAGATCTTATTGATGTTGGATTCACAGATGATGTGAAGAAAGGAGGCCCTGGAAGAGGAGGGAGTGGTGGCTTCACAGCACCAGTTGGTGGACCTGATGGAACGGtgccaatgcccatgcccatgcccatgcctatgccATCTGCAAATACGCCTTTCTCATATCCACTGCCAAAGGGACCATCAGATTTCAATGGACTGCCAATGGGGACTTATCAGGCCTTTCCCAATATTCATCCACCTCAGATACCAGCAACTCCCCCATCGTATGAATCTGTAGATGACATTAATGCTGATAAGAATATCTCTTCTGCACAGATTGTTGGTCCTGGACCCAAGCCAGAAGCCTCTGCAAAGCTTCCTTCCAGACCTGCAGATAACTATGACAACTTTGTCCTACCAGAGTTGCCATCTGTGCCAGACACACTACCAACTGCATCTGCTGGTGCCAGCACCTCAGCATCTGAAGACATTGACTTTGATGATCTTTCCCGGAGGTTTGAAGAGCTGAAAAAGAAAACATAGGTCTCTTAAACCAGGCAACTTTCACGTTTTGGGAGTTGAGACTGAGCAATTTCTCCTTGTAACAAAGAATCTCCATGAAATTCTGTTTCATCTGTTAACCGTCACTCAGCACAACACTCCCTCTGGGCTCTCTTCCTGCTCCTCCAGATTCTGCTGCTTTCCAGTTCTCTGTTGATCCTGAGACTAACAATTGGAGACTGAGGCCAGAGCAACTGGCTCCTGGCAGCTGTGCTTGTCCGTTTCCTGTCAGAGTGATCCCAGGTTTCCTCCTGGCCCGTCCCATGGTCCCTCCACAGGAGTGTGAGAGGATGGGGGAAGCACTGTGGGAAGACCACCAAAGATGGCTGGACAGTGGGAGAGAGCACGTTGTGAAGCATCCCAGCCTCGTGTTGAGGTTCCAGACTTAGAAACAGACCCCTCTGTACAGGGGGATTGTGGTGAGTGAGAATCAAGGCCACCTTGTGTGTTTTCTCACTCTCGAATGCAAGTGGGAGAGGGAAAATGACTCGGGACGCCATTGTAACGGTTCCTGGAAGCTGGGCCCTCTCATTGGCATATACAGTACTCCTCGCTGCAGGGCACTGTCCCACCGGGATCCAGTTGCAAAGTTTGTCTTGACAGTTGAAGGCCTCGCTTAGTTGTACTGGATTCTCAGGGAGCCCTCTGTGGCCTTTTGCTTTGCGTGCTGTTTCCCTTGTACCAGAGGGCGGCACCGTGGAAATTCTGTTTTCCCTGTAGCATATTGTGTTGGATTGCATTACTGGCAGAGAAAGGACAAGGTGCCATTCAAGTCCTAGGGTGGGCTTCCAGCTGCCTTAATAGAAGTACTCAAGTCTTTTGGGTAGTGAGCTGGAAAGCCTACAGGAAAAGAGGGGTACCTGTTTTCATTTGAAAACTTTGATTCATGGAACCTTTAAAACTAATCTCAGAAAAATTTTTGGTGCCCATGCAGCTGTAGTTGTTCACTGCTTTCCTGGATGGATGGGACTCTTATGTCATAACTTCTGTTACTCCTTTGGCCCATAGCTAAGGTCATCCTTCCCCACAGGGGTGGCTTTGGGATTGGATGATACAGCTTTTGCTTCTGTGTAGTATACCTGTACATACTTGTTTCAGGCAGCCTTTCTTTAATGTTTTCAGTTGGTTTGTATTCTGTAGCTCAGTAGCTGCTAATAAAGTTAAAGATCCTGTGTCCTGCTTTCTCTACTGTTTGGTCAGATGATGAAGTATAAATCTGGATTTTAGTGGAGAATATTTTAACCAAGTGATCCATGTAAACCAGCCCTTAGTTTCAGGATTCCTGGAGCAGTACAGAGCTCATTTTGATCTCTGTATTTAGATAGCCCAGATAGCATCTGTGAATTTCCTTGGTCTTCCTCAGTGGCAGGGCTCCGCATCTGCCATGCCTCATCCTTGGATGTTTATTTTTAGTAAGTTGCAGTGAGCTCACTTCTGACTGCTTCATTTCCCGCAGCCATCCTGGGCCATGGGTGGTGAGTTCTGTTACTTGCTGCTTGGCAGCAGAGCTAGTTTGTCTCGTAGTATTCTTGCATTGTTAATCCTATCTTGACAGTGCCAAGATCCATAAGAACTTGGGACCAAGGGGATTTTGATTCCTAACTTACAGAATTAAAAACAAAGTATATTATAATTTTAAAGCTATGCCATGCAAAGATAAGTAGTAATACGCTAATAAATACTAAGCCAAGTAGGAGATAACAGGATTAAGGTAGTTCATCTAAAACTTCAGTGTCACTGCCCACTGCTGTCGTGGCTGCTTGCTCAGATGAGGTTTTTTGGGGCCAACTGATTCCTAACAAATTTGAGAGCTTCTGTAGCAGTGTATCTATTAGTGCAGCTTCTTTCTGAGTATTGAAGACAAAAAGAGAAAAGTGAGAAAATTGAAATTACTGCTAATAGTGGAGTAAAAAAAGTACCAAAGATTTTTAAAAAATTAGTAAATGTAAAGATACTATTTCTTTAATAATTTGCAGTCAGGCATTGGAGTGTTTCCACTAATGGTTGCGAGCCAACTATTTATAGGACAATGGCTATAGAATATTATGTAGTCTTATAAATTGGGTTTCCTAGGAAGATAGCTGGCAGAGCTTTTGAAACTAATAAAGGGAATATGATACTGTGCATTATAAATTATGTCAGCCCGTCATCTTAGGGGCAGTTACAGTGGAGCTTTCCCAGTGATATAACAGCATGCTAGTTTATCTTTTAGTTACCTACCTTAAGCGACTTTCTTTCTTTTCCAAAGGCCATGAGAATGGCCGAAACGAAAAGATTAATTACCACAAGTACCATCAAGATGACACTGGTGAGGATCAGAAAGGTGCCCAGGACTGGGTCTAAAGCGAAAACCTGGGAAAACAATAAGAACACTTGCAGTGACTGACAATTTAGTTTATACTTTACAAACATAAGCTATATGCTAGTGTTTGGGATCTTATCAGAAGAAAAGCTTATCCGAAGGAAACTTAGGGAGAGAGTCAAAAGATAATAAGAAGGAAAATACTTTTAAATGGACAGAAGAGCAGGAATGACTCATTTTAAGGAGGTTAAGATAATTGTGACTGCAGGGCTTTCACAAGAAAACAGGTGAGTTGCAGTGGAATTGGAAATGATTCAAATGTCACATGAGTTTTGGCAAAAAATACATCTAATCATGGAAGCTAAAAGTGGGAGGGGGGTAAGCAAACACTGAAAGATTAAATGCATACCAGAAATGAGAATGCACACTGTCTCTGCCATATCAAGAAACTACAACCCTAAACACAGGAGCATTCCAATAAAAGTTAACAGGTTGGCCACAGAAAACTGGCTTTTTAGTATTTTTTTTTTTCCATTGTCATTTTTAAAGGTACAAGCATTGAGTTCTGCCATTCTTTACTTTTCTGCATACATAAATATCAAGTTCTGGGCTTATTGGAATGGTTCCCATAACAAAAACTGTTGTTTAAAATTTAGATGTTCTTTTTCAACAAATGGTATTTATTTTCCCTTGGTATTGGCCCATTCATTGTTGCCACTAGGGCACTGTTTAAAAATATCCCAACAGAGGGGTTGATTACAGTCAATGCCACCCTGATGGAAATCTATATGGCAAAATATTTTCAAGCACCAAACTGTTTTACCTACTTAAAAATGATTATTATAACAATTTCAGGTCAACCAGATAATGTGGGCAATCTCTGAGTTTGTGATACAAGACTTATTTCCAATAAGTTTATTTTTATGTACAATTTTACTGTTTATTTTTTGTTTGCTCTATTTGTTTTTTAATGTTTTTTACTTTATGTTTACTGTATTTTTATGTACAATTACATCCAAAGCAGAAAAGTTCCTTTTTTATCCCCAAAAGGAGGTGTCAGCAAAAA

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