Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name YME1L1P1
Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr19:54268003-54269482  UCSC
Coordinates (T2T) chr19:57350395-57351874  UCSC
Coordinates (hg19) chr19:54771857-54773336  UCSC
Strand +
Parental Sequence NM_139312.3
Parental seq. overlap 987 bp
Parental seq. overlap (%) 22.4%
Genomic Region Intergenic
Retrocopy Summary YME1L1P1, located on chr19:54268003-54269482, is a retrocopy of the parental gene YME1L1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name YME1L1
Full Name YME1 like 1 ATPase
Also known as FTSH|MEG4|OPA11|PAMP|YME1L
Coordinate chr10:27110111-27155051
Strand -
Gene summary The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes YME1L1P1
Bonobo Pan paniscus YME1L1P1
Gorilla Gorilla gorilla YME1L1P1
Orangutan Pongo abelii YME1L1P1
Gibbon Nomascus leucogenys YME1L1P1
Green monkey Chlorocebus sabaeus YME1L1P1
Crab-eating macaque Macaca fascicularis YME1L1P1
Rhesus Macaca mulatta YME1L1P1
Baboon Papio anubis YME1L1P1
Golden snub-nosed monkey Rhinopithecus roxellana YME1L1P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>YME1L1P1
TTGATGGAAAAGAAGTGGTTACCATGAAGGAACTGAAGTTTTCCAAAGACAAAATTATAATGTGGCCTGACAGAAGAAGTACAGAAATTGATAACAAAAACAAATCCATCACAACTTATCATGAATCTGGTCATGCCATTATTGCATATTACACAAAAGATGAAATGTCTATCAACAAAGCTACAATCATGCCACAGGGGCCAACATTTGGACCTGTGTCCCCATTACCTGGTGATGACAGATGGAATGAAACCAGAGCCCAGCTGCTTGCACAAATGGACATTAGTATGGGAGCAAGAGTGGCAGAGGAGCTTATATTTGGAATTGACCATATTACAACAGGTGCTTCCAGTGATTTTGCTAATGCCACTAAAATGGCAAAGCAGATGGTTATCAAATTTGGAATTAGCGAAAAGCTTGGAGTTATGACCTACAGTGACACAGGGAAACTAAGTCCAGAAACTCAATCTGCTATTGAACATGAAATAAGAACCATTCTAAGGGACTCATATAAATGAGCAAAACTTATTCAAaCCTTAAAAAAAATGAGCAAAACTTATCTTGAAAAGTCATGCAGAGGAGCATAAGAATCTAGCAGAAGCTTTATTGACCTATGAGACTTTAGGTGCCAAAGAGATTCAAATTGTTCTTCAGGGGAAAAAGTTGGAAGTGAGATGAGAACTCTCTTGATGTGGATGCTTTGCTGGTTTTATTGCAAGAATATAAGTAGCATTGCAGTAGTCTCCTTTTGCAATGCTTTCTCCTCATTATTGACGTTGTGTAATTTAAGGGTGTGAAACATTTTGTCAATATTTTGTCACGTTTACCCAATTTTGGTTATTCTCATTATGACACCCATTGCAAATCAGCATCCCATGGCAAATATATTTTTAAAACTAAAGAACTATCAGGATTAAAGACAGCTCATTTGGGAAATGTCAATTAGTTATGAAGTTGAAAGTAACTAATGATTTTATGGTTGGTTACTCTACTAGAGGTGAATAAAACTTCAGCCTTTAGCCTTCTATATACATCAGTGGAAACTTAATTAAGATGCATTAATTATGTTCCAGATTGACCATCAATAAAATGTTTTTAAATCTAAATGTAGAGAA
>NM_139312.3
GTCTGTCGTTGCAGTAGCTGTAGGAAGGGGAGGCCATTTTCCGTTTCTGGGAGGAGTGAGGGGCAACGGGTCGGAGAAAAAGGAAAAAAGAAGGGCTCAGCGCCTCCCCGCCGGGCCGTGGACAGAGGGGCACAGTTTCGGCAGGCGGGTGAGGTCGCTGAGGGCCCGCCGGAGATGTTTTCCTTGTCGAGCACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCCATACACCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTCAAAACCAGCATCGAGATGTAGTTCCTGAGCATGAGGCTCCCAGCAGTGAGtgtatgttcagtgacttcctgacgaagcttaacattgtttcaattggcaaaggaaaaatattcgaagggtacagatccatgttcatggagccagcaaaaaggatgaagaagagcttggacacaaccgataactggcacaTCCGTCCAGAACCCTTCTCCCTCTCAATCCCTCCTTCACTTAACTTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAATCTACTTCCTGGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTCTTTGAAAATAAATATGGTAACTTAGATATATTTAGTACATTACGTTCCTCTTGCTTGTATCGACATCATTCAAGAGCTCTTCAAAGCATTTGTTCAGATCTTCAGTACTGGCCAGTTTTCATACAGTCTCGGGGTTTTAAAACTTTGAAATCAAGGACACGACGTCTCCAGTCTACCTCCGAGAGATTAGCTGAAACACAGAATATAGCGCCATCATTCGTGAAGGGGTTTCTTTTGCGGGACAGAGGATCAGATGTTGAGAGTTTGGACAAACTCATGAAAACCAAAAATATACCTGAAGCTCACCAAGATGCATTTAAAACTGGTTTTGCGGAAGGTTTTCTGAAAGCTCAAGCACTCACACAAAAAACCAATGATTCCCTAAGGCGAACCCGTCTGATTCTCTTCGTTCTGCTGCTATTCGGCATTTATGGACTTCTAAAAAACCCATTTTTATCTGTCCGCTTCCGGACAACAACAGGGCTTGATTCTGCAGTAGATCCTGTCCAGATGAAAAATGTCACCTTTGAACATGTTAAAGGGGTGGAGGAAGCTAAACAAGAATTACAGGAAGTTGTTGAATTCTTGAAAAATCCACAAAAATTTACTATTCTTGGAGGTAAACTTCCAAAAGGAATTCTTTTAGTTGGACCCCCAGGGACTGGAAAGACACTTCTTGCCCGAGCTGTGGCGGGAGAAGCTGATGTTCCTTTTTATTATGCTTCTGGATCCGAATTTGATGAGATGTTTGTGGGTGTGGGAGCCAGCCGTATCAGAAATCTTTTTAGGGAAGCAAAGGCGAATGCTCCTTGTGTTATATTTATTGATGAATTAGATTCTGTTGGTGGGAAGAGAATTGAATCTCCAATGCATCCATATTCAAGGCAGACCATAAATCAACTTCTTGCTGAAATGGATGGTTTTAAACCCAATGAAGGAGTTATCATAATAGGAGCCACAAACTTCCCAGAGGCATTAGATAATGCCTTAATACGTCCTGGTCGTTTTGACATGCAAGTTACAGTTCCAAGGCCAGATGTAAAAGGTCGAACAGAAATTTTGAAATGGTATCTCAATAAAATAAAGTTTGATCAATCCGTTGATCCAGAAATTATAGCTCGAGGTACTGTTGGCTTTTCCGGAGCAGAGTTGGAGAATCTTGTGAACCAGGCTGCATTAAAAGCAGCTGTTGATGGAAAAGAAATGGTTACCATGAAGGAGCTGGAGTTTTCCAAAGACAAAATTCTAATGGGGCCTGAAAGAAGAAGTGTGGAAATTGATAACAAAAACAAAACCATCACAGCATATCATGAATCTGGTCATGCCATTATTGCATATTACACAAAAGATGCAATGCCTATCAACAAAGCTACAATCATGCCACGGGGGCCAACACTTGGACATGTGTCCCTGTTACCTGAGAATGACAGATGGAATGAAACTAGAGCCCAGCTGCTTGCACAAATGGATGTTAGTATGGGAGGAAGAGTGGCAGAGGAGCTTATATTTGGAACCGACCATATTACAACAGGTGCTTCCAGTGATTTTGATAATGCCACTAAAATAGCAAAGCGGATGGTTACCAAATTTGGAATGAGTGAAAAGCTTGGAGTTATGACCTACAGTGATACAGGGAAACTAAGTCCAGAAACCCAATCTGCCATCGAACAAGAAATAAGAATCCTTCTAAGGGACTCATATGAACGAGCAAAACATATCTTGAAAACTCATGCAAAGGAGCATAAGAATCTCGCAGAAGCTTTATTGACCTATGAGACTTTGGATGCCAAAGAGATTCAAATTGTTCTTGAGGGGAAAAAGTTGGAAGTGAGATGATAACTCTCTTGATATGGATGCTTGCTGGTTTTATTGCAAGAATACAAGTAGCATTGCAGTAGTCTACTTTTACAACGCTTTCCCCTCATTCTTGATGTGGTGTAATTGAAGGGTGTGAAATGCTTTGTCAATCATTTGTCACATTTATCCAGTTTGGGTTATTCTCATTATGACACCTATTGCAAATTAGCATCCCATGGCAAATATATTTTGAAAAAATAAAGAACTATCAGGATTGAAAACAGCTCTTTTGAGGAATGTCAATTAGTTATTAAGTTGAAAGTAATTAATGATTTTATGTTTGGTTACTCTACTAGATTTGATAAAAATTGTGCCTTTAGCCTTCTATATACATCAGTGGAAACTTAAGATGCAGTAATTATGTTCCAGATTGACCATGAATAAAATATTTTTTAATCTAAATGTAGAGAAGTTGGGATTAAAAGCAGTCTCGGAAACACAGAGCCAGGAATATAGCCTTTTGGCATggtgccatggctcacatctgtaatcccagcacttttggaggctgaggcgggtggattgcttgaggccaggagttcgagaccagcctggccaacgtggtgaaacgctgtctctactaaaatacaaaaaaatagggctgggcgcggttgctcacgcctgtaatcccagcacttttcagaggccaaggcgggcaaatcacctgaggtcaagagtttgagaccagcctggccaacatggtgaaaccccatctctactaaacatgcaaaaattacctgggcatggtggcaggtgcttataatcccagctactctgggggccaaggcaggagaattgcttgagcctgggagatggaggttgcagtgagctgagatcatgccactgcactccagcctgggcaacagagcaagactctgcctcaaaaaaaaattaaaataaatttaaatacaaaaaaaaatagccaggtgtggggtgcatgcctggaatcccagctacttgagaggctgaggcacgagaattgcttgaacccaggaggtggaggttgcagtgagccaagatcacaggagccactgcactccagcctgggtgacagagtgagactctgtctcaaaaaaaaaTTAAATAAATTATTATAACCTTTCAGAAATGCTGTGTGCATTTTCATGTTCTTTTTTTTAGCATTACTGTCACTCTCCCTAATGAAATGTACTTCAGAGAAGCAGTATTTTGTTAAATAAATACATAACCTCATTCTGAATAATGTCCCTCATTTTGACTATAACTGTGCTTGGTTTCAAAAGCAAAATTAAACAAAAATCTCAGTCCCCTCCGAAGTGAACTTTGTGTTACCCTGCGTCAGAAATGCCAAGTTGTGTTTACTTTTCATTCAGATTTTGTGAATATGAACATGCTGTTATAGGATCTACAGATGAATATTTAACTCAATAGAAAAATTATTTTAGAACACATTGTATTGGTATTACAACCAGATTATATTCTTGACGTTGACTTCATTAAAATTATCTACAATTTCCTAATAATTTAAGCTGTATATGGTCTTCATTGAAAAAAGATAGATATTGTTACAGGAAGCTTGTTACATTATATTCTTGACCTTTTGGTTGATAATCTTAAatcttaatgtaatttcaaactggcagaaatgttgccagcataatacatggatgtctcatataccctgcatccagatttaccagttgttatcattctgcccgttttttatTGCCCCAAACCTGTTCTGTCTCCCTCTCTGTATGTACATACATACACGTATAAAATATTGATAAAGTCTTATCTGTCTTAAATttttttacatatttgttgaggtataatttacatatgataaaattcattttaaatgta

Publications

PMID - Link Title