Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Summary

Retrocopy Name TPRG1LP1
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Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr19:57664650-57665532  UCSC
Coordinates (T2T) chr19:60761579-60762461  UCSC
Coordinates (hg19) chr19:58176018-58176900  UCSC
Strand +
Parental Sequence NM_182752.4
Parental seq. overlap 720 bp
Parental seq. overlap (%) 29.8%
Genomic Region Intragenic (ZSCAN4)
Retrocopy Summary TPRG1LP1, located on chr19:57664650-57665532, is a retrocopy of the parental gene TPRG1L. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TPRG1L
Full Name tumor protein p63 regulated 1 like
Also known as FAM79A|SVAP30|TPRGL|h-mover|mover
Coordinate chr1:3625015-3630127
Strand +
Gene summary Predicted to enable identical protein binding activity. Predicted to be involved in regulation of glutamatergic synaptic transmission. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TPRG1LP1
Bonobo Pan paniscus TPRG1LP1
Gorilla Gorilla gorilla TPRG1LP1
Orangutan Pongo abelii TPRG1LP1
Gibbon Nomascus leucogenys TPRG1LP1
Green monkey Chlorocebus sabaeus TPRG1LP1
Rhesus Macaca mulatta TPRG1LP1
Baboon Papio anubis TPRG1LP1
Crab-eating macaque Macaca fascicularis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.51
log10(TPM+1)

Related Sequence

>TPRG1LP1
CTCCTGCGGAGAATTCCAATTTCCCCCTAAATCGCTCAACAAGCGAGAAGGTTTTGGGATTCGAATTCAGTGGGGCAAGCGAAGTCGCCTTTCCTTCTTAAACAGATGGAATCCCTGGTCCACAAACGTACCCTGTGCCAATTTCATACAACACGCTATGGCTGCTGCGGATGAGAACACAGCAACTCTGCCAGATGAAAAGCTTCAAGGCTCTGTGAATCCAAGGTCAAAAACGCCAAAAAGGAAAGTCCTTTTCCAGGACAAGCGCACGCGTGCTGGTCGTGGAGCGCCCCCTCCTCATGGAGACCGGCCTGGGATTGATGTCCTTCATTAACAATGAGGCTAAACTGGGCTATTCCATGACTGACCAGGGGCAAAATAGGCTTTTAGCCAGCGGCATTCTGGGAGCTCTCCCCACTAAGAAGGCCAAGGGATGTGGGGTCTGAGAGCCTGGCAGTCCTCATGCAAAGCCGCTGCTGGCTGGAAGCATAGGGGTCTTTTACCTTTTGGGATCTCTGCACGATTAGAATAGTAAAGTGGATAGTAATTGCATATTGCACTCTGCTAATGCAAGCTACAGACAAAAGCAAAAAGAATCTAGCTGCCACTGTGCTGCTAGGATTCCATTTTCTGTAACTTCAGTTCTGATACTTTTCCTGGAGTGTATCTACTTGGCTTCTGGCGGTTCTTCCCATCCCAGCCACTCCAGCAGGCTAAATCCCGCAGCACACCCCTTACCATTTGTGTAGGCTGCTAAATACAGGGAGGCACCTGGTATCTCCAGTGTCTGCAGACACAAATATGTTTACACTTGGTGTCaGCTCATACAAAAGCAGCCAGCAGAC
>NM_182752.4
GGCTGCGGCGACGGCGGTCGCGTCGGCGTCAGGGTCGGGGTCGGTAAGGGGTGCGGCAATGCTGCAACTGCGGGACTCGGTGGACTCGGCCGGTACGAGCCCCACGGCGGTGCTGGCGGCCGGCGAGGAGGTGGGGGCAGGCGGCGGCCCGGGCGGGGGGCGGCCGGGGGCGGGGACGCCGCTGCGCCAGACACTCTGGCCTCTCAGCATCCACGACCCCACGCGCCGCGCCCGCGTCAAGGAGTACTTCGTGTTCCGGCCCGGCAGCATCGAGCAGGCAGTGGAGGAGATCCGCGTGGTGGTGCGGCCCGTGGAGGACGGCGAGATCCAGGGAGTGTGGCTGCTTACCGAGGTGGATCACTGGAACAATGAGAAGGAGCGGCTGGTGCTGGTCACGGAGCAGTCCCTGCTTATCTGTAAATACGACTTCATCAGTCTCCAGTGCCAGCAGGTGGTGCGGATAGCGCTCAACGCAGTAGACACCATTTCCTACGGAGAATTCCAGTTTCCCCCTAAATCGCTCAACAAGCGAGAAGGTTTTGGGATTCGAATTCAGTGGGACAAGCAAAGTCGTCCTTCCTTCATAAACAGATGGAATCCCTGGTCTACCAACGTGCCCTATGCCACTTTCACAGAACACCCGATGGCTGGCGCAGATGAGAAGACAGCATCTCTGTGTCAGTTGGAAAGCTTCAAGGCTCTGTTAATCCAAGCTGTCAAAAAAGCCCAAAAAGAAAGCCCTTTGCCAGGACAGGCGAATGGCGTGCTGATCCTGGAGCGCCCCCTGCTCATCGAGACCTACGTGGGACTCATGTCCTTCATTAACAACGAGGCGAAACTGGGCTACTCCATGACCAGGGGCAAAATAGGCTTTTAGCCGCTGCGTTCTGGGAGCTCCTCCCCCTTCTGGGAGCTCCTCCCCCTCCCCAGAAGGCCAAGGGATGTGGGGGCTGGGGGACTGGGAGGCCTGGCAGTCTTCATGCTGCCCTGCTGCTGCTGGAAGGATGGGGATCTTTCACCTTTAGGGATCTCAGCACAATTAGAATCGTAAAGTGAATTCTATCTATTTAATTGGATATTGGACTCTGCTCATATAAGCTACAGACAAAAGCCAAAAGACTCTCGCTGTCCCTGTGCTGCTGGTATTTCATTCTCTGTAACTTCAGTTCTGGTGTTTTCCTTGAGTATCTACTTGGCTTCTCGTGGTTTTTCCCACCCCAGCTGCCCCAGCACGCGGGACCCATAGCACACCCCTTAGCGCTTGCCTAGGTTGCTGAAAACAGGGAGGCACCTGGTATCTCGAGTGCCTGCAGTTGCAAGTATGTTTACACCTGGTGTCCAATTTTGTATTTTAAAATGTAATCCATTTTTACTTCAGCTCATCCAAAAGCAGCCAGCAGACCGGTTGACTGAGACCGGTCTGTGGCTGTGGGCCCCTTGGTGACCCGCTGCTCTTTTGGAAATGGGTGACCTGAAGTGACACTTTTTCCACAATTAACCCAAGTTGTGTTAATACTTCAGGTCTGTTTCCCAGACCCAGAAAGCTTTACAGAAAATCATTGTAAGACAATTTATTAATTTGAGAAAGTCACCTTGACAGTTCTTTGCACACAAGTTTTACACCTCTCTGGATTCGAAGTTTGTATTGTATTCATAGTTAAAGGGAATCGGGTACTTTGCTTGTTGAATAATGCACTTTAAAACAAGGAACCGTATCAGGCCAgcatggtggctcatgcctgtaatcccagcattttgggaggctcaggcagacaaatcgctctagctcagaagttgcagagcagcctgggcaacatggtgaaacccgtctctaccaaacagacaaaaagcagccaggcgtggtggcacatctgtggtcccagctacttgagaggctgagccaggaggatcgcttgagcccaggaggcggaggttgcagtgagctgagatggcaccacttattgcactccagcccgggcgacagagcgagactccatctACCAGATCCTTATGACGCAGCTGATGCCTGCCTTGGTTCCTACCACTCTGGTGTAGACAGAGGACTTTGTCCAAGTCTCACACTAAACATGCCCGGGCTTCGATGTGCCTGGAGGATTTCCCCACAGGGACCCACGCACCTCCCTGTATCTGCGCAGCTTGCTCGTGTGGCTGGAAGCGCTGTCGATAAGCTTCACGCACTGGCTTGCCAGTTCTTCAGCTCTAGGACTTGTAGCTTTAAGCAAACGGTGTGGCATGGGTTGAGTGTGGCCACCTGCAGGATGTGCAGGGCTGCCTCAGAAGCTGGCTGGGGACTCTAGCCTCTGTGTTCATAAAGACATTAAGAAGTGGATGGATGTTGTTCCTTTTTTGAAGTTGTCATTAAAGTAGGTGCAACAACCAA

Publications

PMID - Link Title
No publications available for this retrocopy