Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NDUFS5P2
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:96584418-96584787  UCSC
Coordinates (T2T) chr1:96432516-96432885  UCSC
Coordinates (hg19) chr1:97049974-97050343  UCSC
Strand -
Parental Sequence NM_001184979.2
Parental seq. overlap 321 bp
Parental seq. overlap (%) 64.8%
Genomic Region Intergenic
Retrocopy Summary NDUFS5P2, located on chr1:96584418-96584787, is a retrocopy of the parental gene NDUFS5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NDUFS5
Full Name NADH:ubiquinone oxidoreductase subunit S5
Also known as CI-15k|CI15K
Coordinate chr1:39026350-39034615
Strand +
Gene summary This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17. [provided by RefSeq, May 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NDUFS5P2
Bonobo Pan paniscus NDUFS5P1
Gorilla Gorilla gorilla NDUFS5P1
Orangutan Pongo abelii NDUFS5P1
Gibbon Nomascus leucogenys NDUFS5P4
Crab-eating macaque Macaca fascicularis NDUFS5P1
Rhesus Macaca mulatta LOC114669847P1
Baboon Papio anubis NDUFS5P2
Golden snub-nosed monkey Rhinopithecus roxellana NDUFS5P5
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NDUFS5P2
TCGTCCTGAAGCAGCGGCCAGAGAAGAGACAAGGGCACGAGCATCAGAACGCCATGCCTTTCTTGGACGTGCAGAAAAGGTTTGGCCTTAACACAGATGGGTGGTTGACAATCCAAAGTGCTGAACAGCCCTACAAGATTCCTGCTCGACACCATCCTTTTGAAAAAGAATGGAGAGAATGTGCACATGGAATTGGTGGTATTTGGGGAGAGAAAGAGTGCAGAATAGAATACGACTATTTCATAGAGTGTATACTTTGGCAGAAAATGATGAGATGTGTGAGTACCATCAGGAAGCAGTGGAATAAGCTGATAAAGGAAGGGAAGTACACCCCTCCACCTCACCACGTGGGCAAGGGGGAGCCTCGGCT
>NM_001184979.2
AGTCGTTCTGAAGCGGCGGCCAGAGAAGAGTCAAGGGCACGAGCATCGGCCATGCCTTTCTTGGACATCCAGAAAAGGTTCGGCCTTAACATAGATCGATGGTTGACAATCCAGAGTGGTGAACAGCCCTACAAGATGGCTGGTCGATGCCATGCTTTTGAAAAAGAATGGATAGAATGTGCACATGGAATCGGTTATACTCGGGCAGAGAAAGAGTGCAAGATAGAATATGATGATTTCGTAGAGTGTTTGCTTCGGCAGAAAACGATGAGACGTGCAGGTACCATCAGGAAGCAGCGGGATAAGCTGATAAAGGAAGGAAAGTACACCCCTCCACCTCACCACATTGGCAAGGGGGAGCCTCGGCCCTGAACAGAGCAGCTGCTGATGTCTGGAGGCTGATTTTCCTGTTCTCTGTTCTCCACTGGAAAGGTTGTTTACGACAAACCTCCTTGTCAAAGTGTGTAAAAATAAAGGATTGCTCCATCCTA

Publications

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