Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SEC63P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:97545699-97547224  UCSC
Coordinates (T2T) chr1:97393577-97395102  UCSC
Coordinates (hg19) chr1:98011255-98012780  UCSC
Strand +
Parental Sequence NM_007214.5
Parental seq. overlap 1388 bp
Parental seq. overlap (%) 21.6%
Genomic Region Intragenic (DPYD)
Retrocopy Summary SEC63P1, located on chr1:97545699-97547224, is a retrocopy of the parental gene SEC63. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SEC63
Full Name SEC63 homolog, protein translocation regulator
Also known as DNAJC23|ERdj2|PCLD2|PRO2507|SEC63L
Coordinate chr6:107867756-107958208
Strand -
Gene summary The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SEC63P1
Bonobo Pan paniscus SEC63P1
Gorilla Gorilla gorilla SEC63P1
Orangutan Pongo abelii SEC63P1
Gibbon Nomascus leucogenys SEC63P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SEC63P1
ACTGCCAACTAATAGTAATGGCCCCGAACCGTGAAGAAAGGGAATTTCGTGCTCCAACTTTGGCATCCCTAGAAAACTGCATGAAGCTTTCTCAGATGGCCGTTCAGGGACTTCAGCAATTTAAGTCTCCCCTTCTGCAGCTCCCTTACATTGAAGAGGACAATCTTAGACAGGTTTCTAATCATAAGAAGTATAAAATTTAAACTATCCAGGATTTGGTGAGTTTAAAGAATCAGATTGTCATACTCTACTGCACTTCCTTGAAGATGAAAAATATGAAGAGGTTATGGCTGTCCTTGGGAGTTTTCCATATGTGACCATGAATATAAAATCACAGGTGTTAGATGATGAAGACAGCAACAACATCACAGTAGGATCCTTAGTTACAGTGCTGGTTAAGTTGACAAGGCAAACAATGGCTGAAGTATTTGAAAAGGAGCAGTCCTTCTGTGCTGCAGAGGAACAGCCAGCAGAAGATGGGCAGGGTGAAACTAACAAGAACAGGACAAAACGAGGATGGCAACAGAAGAGTAAAGGACCCAAGAAAACTGCTAAATCAAAAAAAAAGAAACCTTTAAAAAAAAAAACCTGCACCTGTGCTATTACCACAGTCAAAGCAACAGAAACAAAAGCTGGCAAATGGAGTTGTTGGGAATGAAGCTGCAGTAAAGGAAGATGAAGAAGAAGTTTCAGATAAGGGCAGTGATTCTGAAGAAGAAGAAACCAATAGAGATTCCTGAAGTGAGAAAGATGATGGTAGTGACAGAGACTCTGATAGAGAGCAAGATGAAAAACAAAACAAAGATGATGAAGCAGAGTGGCAAGAATTACTACAAAGCATACAGCAAGAAGAGAGCGCTCTATTGGAAACCAAATCAAAAATAACACATCCTGTGTATAGCCTTTACTTTCCTGAGGAAAAACAAGAATGGTGGTGGCTTTACATTGCAGATAGGAAGGAGCAGACATTAATATCCATGCCATATCATGTGTGTACACTAAAAGATACAGAGGAAGTTATGGGTTTGGATCAGATTAAACCATTGAAGTTGGAAGTTCATGAGGCCAAGCCTGTGCCAGAAAATCACCCACAGTGGGATACAGCAATAGAGGGGGATGAAGACCAGGAGGACAGTGAGGGCTTTGAAGATAGCTTTaCTAAGCAGTACTCTGAATGGACCATAGTGTTTGCACATATTTGCAATTTTTTGCTGTTTTGGAAGTTTATCATAAACCAGAAACAGTACAGAACTGATGTTGAGGGAGGTGTAGTTTTTTTACTCTAGAAATGGGTGCATAATATAACTAGGCAGTGGCAGTGCCTTGGTACAACCTGAAAAATGTTAAGGCTTACTGAAACCTTTCAAGTATGGGATGGTGCATTTATTTCATCTGCAAATGATAATAAATCCTTTGTTATTAT
>NM_007214.5
CTCTCGCGAGAGCTggcgacggcggcggcagcggcagaggtggcggcggcgtgtccgtgagagtggcgtgggggcggggaggagaggcggcggcggcAGTGTCCAAGCTACGCCACTCGGGCCGGGGCGTTGGGAGCGGGAGTGCAGAGCGTGGTCGTGGCGGCGGCGGTGAGAAGAGCGAGGCGGAGGAGGGGGTGCCATGGCCGGGCAGCAGTTCCAGTACGATGACAGTGGGAACACCTTCTTCTACTTCCTCACCTCCTTCGTGGGGCTCATCGTGATCCCGGCGACATACTACCTCTGGCCCCGAGATCAGAATGCCGAGCAAATTCGATTAAAGAATATCAGAAAAGTATATGGAAGGTGTATGTGGTATCGTTTACGGTTATTAAAACCCCAGCCAAATATTATTCCTACAGTAAAGAAAATAGTTCTGCTTGCAGGATGGGCATTGTTCTTATTCCTTGCATATAAAGTTTCCAAAACAGACCGAGAATACCAAGAATACAATCCTTATGAAGTATTAAATTTGGATCCTGGAGCCACAGTAGCAGAAATTAAAAAACAATATCGTTTGCTGTCACTTAAATATCATCCAGATAAAGGAGGTGATGAGGTTATGTTCATGAGGATAGCAAAAGCTTATGCTGCTTTAACGGATGAAGAGTCCCGGAAAAATTGGGAAGAATTTGGAAATCCAGATGGGCCTCAAGCCACAAGCTTTGGAATTGCCCTGCCAGCTTGGATAGTTGACCAGAAAAACTCAATTCTGGTTTTACTTGTATATGGATTGGCATTTATGGTTATCCTTCCAGTTGTTGTGGGCTCTTGGTGGTATCGCTCAATACGCTATAGTGGAGACCAGATTCTAATACGCACAACACAGATTTATACATACTTTGTTTATAAAACCCGAAATATGGATATGAAACGTCTTATCATGGTTTTGGCTGGAGCTTCTGAATTTGATCCTCAGTATAATAAAGATGCCACAAGCAGACCAACGGATAATATTCTAATACCACAGCTAATCAGAGAAATTGGCAGCATTAATTTAAAGAAGAATGAGCCTCCACTTACCTGCCCATATAGCCTGAAGGCCAGAGTTCTTTTACTGTCTCATCTTGCTAGAATGAAAATTCCTGAGACCCTTGAAGAAGATCAGCAATTCATGCTAAAAAAGTGTCCTGCCCTACTTCAAGAAATGGTTAATGTAATCTGCCAACTAATAGTAATGGCCCGGAACCGTGAAGAAAGGGAGTTTCGTGCTCCAACTTTGGCATCCCTAGAAAACTGCATGAAGCTTTCTCAGATGGCCGTTCAGGGACTTCAGCAATTTAAGTCTCCCCTTCTGCAGCTCCCTCATATTGAAGAGGACAATCTTAGACGGGTTTCTAATCATAAGAAGTATAAAATTAAAACTATCCAGGATTTGGTGAGTTTAAAAGAATCAGATCGTCACACTCTACTGCACTTCCTTGAAGATGAAAAATATGAAGAGGTTATGGCTGTCCTTGGGAGTTTTCCATATGTGACCATGGATATAAAATCACAGGTGTTAGATGATGAAGATAGCAACAACATCACAGTAGGATCCTTAGTTACAGTGTTGGTTAAGTTGACAAGGCAAACAATGGCTGAAGTATTTGAAAAGGAGCAGTCCATCTGTGCTGCAGAGGAACAGCCAGCAGAAGATGGGCAGGGTGAAACTAACAAGAACAGGACAAAAGGAGGATGGCAACAGAAGAGTAAAGGACCCAAGAAAACTGCTAAATCAAAAAAAAAGAAACCTTTAAAAAAAAAACCTACACCTGTGCTATTACCACAGTCAAAGCAACAGAAACAAAAGCAGGCAAATGGAGTCGTTGGGAATGAAGCTGCAGTAAAGgaagatgaagaagaagtttcagataagggcagtgattctgaagaagaagaAACCAATAGAGATTCCCAAAGTGAGAAAGATGATGGTAGTGACAGAGACTCTGATAGAGAGCAAGATGAAAAACAAAACAAAGATGATGAAGCAGAGTGGCAAGAATTACAACAAAGCATACAGCGAAAAGAGAGAGCTCTATTGGAAACCAAATCAAAAATAACACATCCTGTGTATAGCCTTTACTTTCCTGAGGAAAAACAAGAATGGTGGTGGCTTTACATTGCAGATAGGAAGGAGCAGACATTAATATCCATGCCATATCATGTGTGTACGCTGAAAGATACAGAGGAGgtagagctgaagtttcctgcaccaggcaagcctggaaattatcagtatactgtgtttctgagatcagactcctaTATGGGTTTGGATCAGATTAAACCATTGAAGTTGGAAGTTCATGAGGCTAAGCCTGTGCCAGAAAATCACCCACAGTGGGATACAGCAATAGAGGGGGATGAAGACCAGGAGGACAGTGAGGGCTTTGAAGATAGCTTTgaggaagaagaggaggaagaagaagatgatgactaagcagTACTCTGAATGGACCACAGTGTTTGCACATATTTGCAATTTTTTGCTGTTTTGGAAGTGTATCATAAACCAGAAACAGTACAGAACTGATGTTGAGGGAGGTGTAGTTTTTTTACTCTTGAAATGGGTGCATAATATAACTAGGCAGTGGCGGTGCCTTGGTACAACCTGAAAAATGTTAAGGCTTATTGAAACCTTTCAAGTAGGGGATGGTACATTTATTTCATCTGCAAATGATAATAAATCCTTTGTTATTATAACTGTCCAGAAGTGTGGGCTATGTATTATCTGATCAGTCTATGGTCCCAGTAAAAGTAAAGATGCAGGAAACACAGTCTGTAAATGAGCGACTTTTCTTTGTTCAGCTTTAGTTTTAGCAAACACCACAAATATGTTTTAAGTAACATCGCTCAAGTTTAAGTAACATCGCTCAAGTTGATAATCTCTTGATAAGCTCTGTTGTTGACATTTTGCAGTGATACAACAGCTCCACTCATAGATTTAAACTTTTATTTTTACTTATCTTGGTCATAAGTTGGCATTCTCTCACATTCCACATGATATAGAGGGCTACGTTTTGGAATTTTCCTTTTCTTAATTGCCCAGAGTTATCAGACAGATTATAAAAATGGCTTTTAATGGCTTAAACCATTTCTAAACCTCTATCTTAGCAGATCAATGCAGGATCTAATTCTTTTGATAAGTTCTAGCTCTAAAAGTGATAGTGGGACTGTATGTTTTCTGATACTGGTGGCTTATGTTATTAAACCTTTTTTAAAAAAGGTTCACTCTAAAAGCTGAACTACATCCTTAGTTTTCAGTCTACTTGACTCTATCAGGAGCTTTTTAAGGAAAGTAAGTATAACATGCAAAGGAAGCTTTTTTTGTATTCATTTTGGACTCCTGTCAATAAAAATAGAAGTTTGTTGACTCGTTTTATGTTTCAATGGTGTGTGTCTTTTTACTATCAGGACATAAATAGGGCAATCCACTTCTTTATTTTTCAACTAAAGATTGAATAGTATTGTACATTACTGCTAAAGTGACTGCTATTTCTGTATACTGTAGAAAAACCCAGGAGTGAGAGGGATTTCCCCTCATAGTACAACTGGAAGGATAGTGCTTGTAAAGAGTAGAGATGTGTACATGATGAATCATTGAGGGAGGGTGGATATTTTTATTCCTAGATATGGAGGAAACATAAGTCTGTAGTATTATAAAACTGATTGTAATAATTCTTTCCTATCAAAATCTCCATAGGTCAAAATATTGTTGGAATACTAAAATTTGCAACCTTGTTTACTTTAAAAGGTTGCCACTTTCAGTGCAGAATACTACCGGCATCTTGTTACTGCAATAGTTGGAAATAAAATGTGAAAATTAGCAAAACCATGAATGGTTTTTTTGGTTCTAAATTTAAGATGTAATATTTCCTATAAAAGGGTGAAAGCAGTTTCTTTCTCTATAACCTCAATCACCAGTTTAGTGAGAGCCTTTCTTGGCAGGCAGGAGGCAGTGTCACTGAGGATTTTTTTCATTTACTTCATTGTACAAGTAGGAGGGTGGGTTTAATTTTCAAATCAGGTTCTGCTGTGAAGCACCAGTGTCTTGAGGCAGCTACTGATTACCTAAGTGTGGTGGCAGGGGGTAAGCCAGCTGGTGTCAAGTGAAAGGAGGGATTAGAGAAAACAGGTGTGGCACGAAGGCAAGGAAACTGAGCAGACAAGACAGAACAATGTGTAGAATGCATATTTCCTAGTTTTCTTGAAAGATTTCAAGAAAAGTTGTTTTTTTTTTTCTAGTGGCTACTTTGCCTTAAAGAGGCTTTATAAGTTCATTCACACAGCTGGCTTCTCTGGTTTTAAGATTCTGGAGAGGATGATAACCTAGTAACACCACAGTGCTTaaaaaaaaaaaaaaaaaaaaaaCTACCATCACCAGAAAATTCCACCAGTTTGTTTTCCTTTTCTCTTTGTGTGATGTGTATGTACTTCCCAACTAAGTAAAATAAAATTTCCTCTAGTGAGTGCTTTAGGTAACCTCTTTCCATATGGCAGTAGTGAAAGAACTGAGCCTTCAGTTGATAGTTCTTCTCTCTCCAGCAAGTCGCTAAACTCCACATCCCTTCGTTTTTCCTCTGGAATGAGAATAACAAACTATCCTAGTTTGCATTTAATCTAATGGAAACTTGAGCAAAGTTTCAATTTTCTTCCTATAAAGAAACTGACATTTTGTCAACAATTGATGAGCCTATAGATCATACAGTGTATAGGAAGTGAAATTGAAACAGTTAAATTATGTGATATTTTTCTCTAATTGGTAAAGTACCTATTAAAATACAGCTGTTCATGAGGAGACTTACCACAATTCAAAGTGTAGCAGTTGTGTATTTTAGCATTATAATATTTGATTGAGGCCCTGAGGTGTTAATATCTCAATCTCAGAGTTAGATGTTCATGTCCTTTTTGAATTTTTTAAACATTTTTCATAATTTTTTTTTTAAGTTAGGGAGCACATTGAGTGAAGTTCTCTGTGTAGAACAATACCTTCTGCTCTGCTTCTCCCAGCTTTCACTGAGGGCTGGAAAAGGACAGGCCTGTCCAGCTGTACTGTCCCACTGTGTATGGGGAAGCTCAGGCTCTGGTGGAAGCAGGGGGCGTGGATGTCAAACAACTGATGTGGAAACAGGGAGGGAGAGATATAATGAGGCTCTCTAGGCATGTTATTTTTGACCACAAGTTTTGTTCAGTTTGCTTCAGCCAATCCAAACCATATACTAGAGTGTTCTGTAGTCACAATTCTTATTTCAAATGTAATTCAGCACCTTACATAATTTTTGAGAGGTTGtcattcatcacatatttactgagtttctatgtgccaggctctgtgactggatactggagctatcaaaatgaaaaaaatagtgttaagaactcactcgctggtgttagagcaggtagatgagtGGCAATCCATTTAAATCCATTTGCCTTGGCTATTATTTGGAATGCCTTTTTTTTTTTTTAGTCTATCTACTGTAGGCAGAAGAATTATTTCTTTAGGGGCTAGCTGTTTATTTTGCTGGCCtttttttctctctttctctttttcttcttaagacggagtctcgctctgtcctccaggctggaggagtgcagtggcacgatctcagctcactgcaacctccgcctcccagcttcaagcgattcttctgcctcagcctcctgagtagctgggactgcaggtgcatgccaccacacccagctaattttttaatttttagtagagatgggattttgccacgttgtccagcctggtctcgaactcctggcctcaagtgatcagccctcctcagcctcccaaagtgctggcattacaggcatgagccactgcgcccagccTGTTGGGTTTTTTTGGAAAAAAAACAAAAACAACAAATCATCATCCTTTCCTTTAAAATGTTTTTTTTTTTTTAAGAAACAATTTTCCCACAAACGGTCTGATTTAACTCCATGAAATCCTCTATTTAGACTGCCTTAAAGTGAAATAACTGTTGGTGAACCATAACATTTTGCCAGCTGTGTAGTGATTAGTCCAAATATGTCTCAAGAAGTTAGCACCAAGCATTCTCATCCATTTAAACTTGATGCTAGGGCTATTTTGCAAAACTTAAAAAGATGCGATCTTGTACATATTTCTGTAACCTGAGCTGAAAACCCAAATAACAATCATTGACATACTTTAGGGCTATTGTTTCAGGTGggggtgtatacatcccaggggcgtggagatgatcaatccattgaggaagtattaagatgattatttgtatttaatctcatccttttaaatttctatttttgtgtgttttataatgtacataatatattgtacaattgtacacttctattatttataaataaacatttattggtgcattaa

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