Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MZT1P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:9781073-9782450  UCSC
Coordinates (T2T) chr1:9323859-9325236  UCSC
Coordinates (hg19) chr1:9841131-9842508  UCSC
Strand +
Parental Sequence NM_001071775.3
Parental seq. overlap 1000 bp
Parental seq. overlap (%) 44.8%
Genomic Region Intragenic (CLSTN1)
Retrocopy Summary MZT1P1, located on chr1:9781073-9782450, is a retrocopy of the parental gene MZT1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MZT1
Full Name mitotic spindle organizing protein 1
Also known as C13orf37|MOZART1
Coordinate chr13:72708367-72727629
Strand -
Gene summary Involved in gamma-tubulin complex localization. Located in centrosome and spindle. Part of gamma-tubulin large complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MZT1P1
Bonobo Pan paniscus MZT1P1
Gorilla Gorilla gorilla MZT1P1
Orangutan Pongo abelii MZT1P1
Gibbon Nomascus leucogenys MZT1P2
Crab-eating macaque Macaca fascicularis MZT1P1
Rhesus Macaca mulatta MZT1P1
Baboon Papio anubis MZT1P1
Golden snub-nosed monkey Rhinopithecus roxellana MZT1P2
Marmoset Callithrix jacchus MZT1P1
Green monkey Chlorocebus sabaeus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MZT1P1
ATTCTGCTTGAGATTTCAAGAATTTAGAATGCTGGCTTAGATATGGAAACTCCTATTTGTGTACGGCTTTGTGAACAAGAAATTAACCCAGAAGCTTTATCATCAGTTATTAAGGAGCTTCGCAAGGCTACTGAAGCACTAAAGGCTGCTGAAAATATGACAAGCTGATTTTCTGGGGAAATTCTGATGAGATATGTCAAGCTCTGCAAGAGGATTTAAAGATTGCACTGTAGTCGAGAATGTACAATGATACTGAATGCAGCAGTGTAGAAAAATTTTCCTTTTTAAAAGAATTATAAAACCATAGCATTATAAATCAGTGGAAAGTGGCTTACAGACAGAACTATCAGATGTGTTTACATCACATCcTTATTCACTTTTTTTAACGGCTCTAATGCTTCCACATCGCCATGTTCATATTTATGTATTCTTTATTTATAGCTTTGATAGCTTTAATTTTCTAAGCAGTCTATCAGATGTGCACATCTGCTGTGCCTGTAGTGGAACCCATCAGTAGTAATGTGTAGTAGTTGTGACTTGTTGACATTTCCACTATAAATTTTAACTTTGAATTGTTTATGCATTATAACTGTGGATTTATATTGTATTGGGCTGAAAGCTGACACTATTTCAGCCACCATTGGTGAATTCTGATTTAGATTCATTATGTATGTCGGAATCTTGTTTTTTAAAATAAGAGCATGGAAAACATTTCTTGCAATCTGATCTTTAACAAAGAATACTTAGTTTTTTAAACAGTTTGTTGGGCAGCTAATAATGTGAACCAGGTCATTTTTGTATTGAGTAAAAATTTAAACTTCTAGAAACTTAGATTTTAAAAGTAATGACAATGCTTAGGTTAGTATTATTTGCAATTCGAATCATTTACAGCTAATGAGAATGTTTTCTTAAAGTTTTATACCCTATAAATGGAGGCCTAAAAAAATGTGTAAAATGAAACATAGCAAACATGCCAAACTCCTGTTTACTTTTCTTACATAAAAGTAATTTGAGTCCTTGACTAATAAATCTTGAATGGTTATTTAATAAGTTATTAGGTAAGTAATGTGTTTCAAAA
>NM_001071775.3
CTTCTCCCGCCTCCCTCGGCCTTAGCCATGGCGAGTAgcagcggtgctggggcggcggcggcggccgcggcggcgAATCTGAATGCGGTGCGGGAGACCATGGACGTTCTGCTTGAGATTTCAAGAATTTTGAATACTGGCTTAGATATGGAAACTCTGTCTATTTGTGTACGGCTTTGTGAACAAGGAATTAACCCAGAAGCTTTATCATCGGTTATTAAGGAGCTTCGCAAGGCTACTGAAGCACTGAAGGCTGCTGAAAATATGACAAGCTGACTTTCTGGAGAAATTCTGATGAGATATGTCAAGCTCTGCAAGAGGGTTTGAAGATTGCATTGTAGTTGAGAATGTACAATGAAATTACTGCATGCAGCAGTGTAGAAAAATTTTACTTTTTAAAAGAATTATAAAACCATAGCTTTATAAATCAGTGGAAAGTGGCTTACAGAGAGAACTATCAGATGTGTTTACATCACATCTTATTCACTTTTTTTAACAGCTCTAATGCTTTGGCATTGCTATGTTCATATTTATGTATTCCTTATTTATAGCTCTGATAGCTTTAATTTTCTAAGCAGTCTGTCTATCAGATGTGCACATCTGCTGTGCCAGGTTGAAGTATAGTGGAACCCATCAGTAGTAATGTGTAGtagttatgacttgttgacatttccattataaactttaattttgaattgtttatgcattataactgtggatttatattgtattgggctgaaagttgacaggatttcagccaccacttgtgaatttttatttaGATTCATTATGTATATCAGAATCTTGTTTTTTGAAATAAGAGCATGGAAAACATTTCTTGTAATCTACTCTTGAACAAAGAATATTTAGTTTTTCAAACAGTTTGTTGGGCAGCTAATAGTGTGAACCAGGTCATTTTTGTATTGAGTAAAAAAATCAAACTTTGAGAAACTTGGATTTTAAAAGTAATGACAATGCTTAGGTTAGTATTATTTGTAATTTGAATCATTTACATCTAATGAGAATGTTAGTTGAGAATGTTTTCTTAAAGTTTTATATCCTATAAATAACGGAATAAAAAAATTTGTAAAATGAAACAACAAACATGCAAAATTCCTATTTACTTTTATTACATAAAAGTAATTTTAGTGCTTACCTAATAAATCTTGAATGGTTATTTAATAAATTATTAGATGGGTGATGTGTTTCAAAAGATACTTGCTATTTTTTGAAGAAATAAGGATTTCCAGTCATTAAACAAAACTAAACAATCTTATTAGATGGGTGATGTGTTTCAAAGGATACTTGCTATTTTTTGAAGAAATAAGGATTTCCAGTCATTAAACAAAACTAAACAATCAAATGTTCTATATTAGGAATCTCAAGTATGGCTTTTTTTAAAAAACCTTTTTAACATCTTGATGTCAAGGATTATAAGTATGGCTTTTCAGAATTGTTTTGTTTGTCATTATTCTTGCCTTTAAAATTTTAACTCATCAAAGTGAAGATTAGAAATAAATTTTAGAAAATGTAGAATAGTATTGATTCTGTTCCTGTAATAGAATCTCAGTGGAGTTTTTTTGCAAAACTAATATGGATTTCATCTGATTTTATTATTTCTTAAATTTTAGATTTTATTGAGTACCATTTATATGATTGTACAAGCATTCACTCTTTACTAGCATTTTTTGTTTTTCAGACAAGCTGAAGTGGTTTTATTAAGATTTGGTAATATTTAAATAGCAACCTTCTCTGCCTTTTTTTTTTTTTAATATAGAATTTTGACCATTTTGACTTTTTAAATGCCTGGCATCTTTACCAACCAAGTAAACTGGAAGATCTGTTACTGGTAGAACAGGTTGAGGAGACAGTAGGAATTTGTAAAAAGTCATTTGATTTATAATCAACACTACAAATACTATGTGTTATTTATAAAATCATAAAGAACACTTTTGTCAGACTCCAAAATTTGTATATACTTCCAGGCCATAAGAGTTGATAGTATTATTTATGACTTTGTAGATTAAGTTATTTATGTATGAAACAAAGCAGGAAAATATATTGAGAAGGGATCGTGTTTACAGAGGACTTCTTTAAAGTGTCACATTTTTAAAATGTAAACATATTTTTAATGCATACTTAAGTAATATTTAAGAAACTAAACAAAATAATGATACAATTGCAGTGTTGTGCTTGTTGTCAATGACAAAAATAAAACCATTTTGGTGGTA

Publications

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