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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ANAPC13P2
Plot displaying the genomic locations of a retrocopy (in chr20) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr20:11838320-11838608  UCSC
Coordinates (T2T) chr20:11881612-11881900  UCSC
Coordinates (hg19) chr20:11818968-11819256  UCSC
Strand +
Parental Sequence NM_015391.4
Parental seq. overlap 251 bp
Parental seq. overlap (%) 21.5%
Genomic Region Intergenic
Retrocopy Summary ANAPC13P2, located on chr20:11838320-11838608, is a retrocopy of the parental gene ANAPC13. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ANAPC13
Full Name anaphase promoting complex subunit 13
Also known as APC13|SWM1
Coordinate chr3:134477704-134486023
Strand -
Gene summary This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ANAPC13P2
Bonobo Pan paniscus ANAPC13P2
Gorilla Gorilla gorilla ANAPC13P2
Orangutan Pongo abelii ANAPC13P2
Gibbon Nomascus leucogenys ANAPC13P1
Green monkey Chlorocebus sabaeus ANAPC13P1
Crab-eating macaque Macaca fascicularis ANAPC13P2
Rhesus Macaca mulatta ANAPC13P2
Golden snub-nosed monkey Rhinopithecus roxellana ANAPC13P2
Marmoset Callithrix jacchus ANAPC13P1
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ANAPC13P2
AGGTGCAGATCTGACAAGGTTAAAGCTCCAGGAAAATGAACAGTGAGGTACAAAGAGATGGAAGAATCTTGGATTTGATTGACAATGCTTGGTGAGAAGACAGGCTACCATAGGAGGACGCTGCAGTTCCACTGAATGAGCTTCCTAAACCAGAACAAGACAATGTTGGCTCCCAGAATCTGCCAAAGAACAAGAAATGAAGTGTACAGACTTAACCTTACAGCACCTCCATGAGAACATTCCCCTCACTGGAAACTGACACTTGGCTCCTTTCTCATGCATGGATTTT
>NM_015391.4
AGGAGCAAGCGTCTGCCGCGGTGGCCGGGTGCCGATTTGACAAGATCAAAGCTGCAGGAAAATGGACAGTGAGGTTCAGAGAGATGGAAGGATCTTGGATTTGATTGATGATGCTTGGCGAGAAGACAAGCTGCCTTATGAGGATGTCGCAATACCACTGAATGAGCTTCCTGAACCTGAACAAGACAATGGTGGCACCACAGAATCTGTCAAAGAACAAGAAATGAAGTGGACAGACTTAGCCTTACAGTACCTCCATGAGAATGTTCCCCCCATTGGAAACTGACGCTTGGCTCCTTTCTTGTGGATGGATTTTCTCAAAGTACACAGATAAAGCATGGTTTGTTTCAGTCTCCAAATTCAAACCTTTGAGTAATAAATCAGCACTCAAAAATGTACACCCATTTAGTTTGTGGTAGCAAAGTGCAATGCGAAATTGAATGAGAAACTGAGATTTCTCAGTAATGGTGAATATTTCGCTCTTTAAACCTAAAACTCTTCATTGAGTAGCTTATATTTGAACATGATTGGTTAAACATTTGCCTCTACCTCTGATTTTGCTTTGCTGTCAAAGTTTAACACCTTCCAACTACTTATGTGTGTCCTGTAACACAGGTGATTGAACGTATGAGAGGGAAAGGCAAAGAAAAAGGAAGCCAGACACTAGGAGAATTATTAACTTCTCATACTTCCCCACATTGAGAAGCATTCGGAGTGTATTTAGCCTGTAGATGTTGTGATATGCAAATATCCCATTCCCTGGTTACTGGCATTCCTAAGATTCTTCATGGTATTTTCAAACTTTGGATAAATTTACAGATTAGAAAGATATCTGACAGTTAATCTCTGTTCTCCTTACAAATTCCTTTTGTGCTGCTGGAAAGGATCTTTGGCTAGGTGGATGACTAGTTTTATTCAAAGCCTTTTCTCAAAGCCCTTTCAGTTACAACCACCCCACTATGGAATCAGTATTTAGTTATACATTTGTATAAGAACCTGTATTTTGAAAAACACATTCATGTATATTTATTCCTGGAATTATTTGCCTGTTAAACAGTGTCTTTCATGTTCTCTCCCCAGATTGTAAACTCTGTAAGAAGCTGCTTGTATCTGTATCCCTTGTTGAAACTCTGAAAACACTGAATAACTAAAATCTCTTCTCATCCTTTT

Publications

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