Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name VTCN1P1
Plot displaying the genomic locations of a retrocopy (in chr20) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr20:25099042-25101596  UCSC
Coordinates (T2T) chr20:25163660-25166214  UCSC
Coordinates (hg19) chr20:25079678-25082232  UCSC
Strand +
Parental Sequence NM_001253849.2
Parental seq. overlap 2097 bp
Parental seq. overlap (%) 77%
Genomic Region Intergenic
Retrocopy Summary VTCN1P1, located on chr20:25099042-25101596, is a retrocopy of the parental gene VTCN1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name VTCN1
Full Name V-set domain containing T cell activation inhibitor 1
Also known as B7-H4|B7H4|B7S1|B7X|B7h.5|PRO1291|VCTN1
Coordinate chr1:117143587-117210985
Strand -
Gene summary This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes VTCN1P1
Bonobo Pan paniscus VTCN1P1
Gorilla Gorilla gorilla VTCN1P1
Orangutan Pongo abelii VTCN1P1
Crab-eating macaque Macaca fascicularis VTCN1P1
Rhesus Macaca mulatta VTCN1P1
Baboon Papio anubis VTCN1P1
Golden snub-nosed monkey Rhinopithecus roxellana VTCN1P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>VTCN1P1
TATGCTAAAGAGCCGCAGATTGGGTCTTCATGAAAACAAAGAAAAAGCCATGAAGTTTCTACAGCATAATTAGCATCATCATTACTCTGGCTGGAGCAATTGCACTCATCATTGGCTTTCGTATTTCAGGGAGACACTCCATCACAGTCACTACTCTCACCTCAGCTGGGAACATTGGGGAGGATGGAATCCTGAGCTGCACTTTTGAACTTGACATCAAACTTTCTGATATCATGATACAATGGCTGAAGGAAGGGGTTATAGGCTTGGTCCATGAGTTCAAAGAAGGCAAAGATGAGCTGTCAGAGCAGGATGAAATGTTCAGAGGCCTGACAGCAGTGCTTGCTGATCAAGTGATAGTTGGCAATGCCTCTCTGCAGCTGAAAAACATACAACTCACAGATGCTGGCACCTACAAATGTTATATCATCACTTCTAAAGGCAAGGGGAATGCTAACCTTGAGTATAAAACTGGAGCCTTCAGCATACCAGAGGTGAAAGTAGACTATAATGCCAACTCAGAGACCTTGCGATGTGAGGCTCCCTTATGGGTCTCTCAGCCCACAGTGGTCTGAAGATCCCTAGTTGACCAGGGAGCCAAATTCTCAGAAGTCTCCAATACCACCTTTGGGCTGAACTCTGAGGATGTGGCCATGAAGGTTGTGTCTGTGCTCTACAATGTTACGATCAACAACACATACTCCTGTATGATTGAAAATGACATTGCCAAAGCAACAGGGGATATCAAAGGACAGAATCTGAGATCAAAAGGCGGAGTCACCTACAGCTGCTGAACTCAAAGTCTTCTCTGTGTGTCTCTTCTTTTTTTGCCATCAGCTGGGCACTTCTGCTTCTTGCCCCTTACCTGATGCTAAAATAATGTGACTCGGCCACAAAAAAGCATGCAAAGTCATCGTTACAACAGGGATCTACAGAACTATTTTGCCACCAGATATGACCTAGTTTTATATTTCTGGGAGGAAGTGAATTCATATCTAGAAGTCTGGAGTGAGCAAACAAGAATAAGAAACAAAAAGAAGCCAAAAGCAGAAGGCTCCAATATGAACAAAAATAATCTATCTTCAAAGACATATTAGAAGTTGGGAAAATAATTCATCTGAACTAGACAAGAGTAATAAGTAAAATGCACGAGGAGACAAGTGCATCCCCAGATCTCAGGGACCTCCCCCTACCTATCAACTGGGGAGTGAGAGGATAGGATAGTGCGTGTTCTTTGTCTCTGAAATTTTAGTTATATGTGCTGTAATGTTGCTCTAAGAAAGCTCCCAGAAAGTCTCTATCCCAATATATACACATCTTATATTCCATGAATACTTTTCATGATGCTTCCAAAGGTGCCTCAGTTTCTCTTCCCAACTGAAAAATGCCAAAGATAAGAAAAATGATCATAATTTTAGCATAAACAAACCAGTCTGTGACACCGATTTTATAAGTAAACTGAGCACCATCTTTTCAAACAAATGCGGGTTTATTTCTCAGATGATGTTCATCTGTGAATGCTCCAGGGAAGGACCTTTCACCGTGACTATGTGGCATTATGTCATCACAAGCTCTGAGGCTTCTCCTTTCCATCCTGCGTAGATAGCTATGACCTCAGTTTTCAATAGCATCTAGAGgATTTAGAGTAGAAAAGGGCCTAGCAAGAGGGGAACAAACAAGTCTGTCTGCTTCCTCACATTAGTCATTGGCAAATAAGCATTCTGTCTCTTTGGCTGCTGCCTCAGCACAGAGAGCCAAAACTCTATCGGACACCAGGATAACATCTCTCAGAGAACAGAGTTGACAAGGCCTGTGGGAAATGCCTGATGGGATTATCTTCAGCTTGTTGCGCTTCTAAGTTCCTTTCCCTTCATTCTACCCTCTAAGCCAAGTTCTGTAAGAGAGCTGCCTGAGTTCTACCTCAAGTTTTCTTACTCTGAATTTAGATCTCCAGACCCTGCCTGGCCACAGTTCAAATTACGGCAACAAACATATACCTTCCATGAAGCACACAGAGACTTTTGAAAGCAGGGACAATGACTGTTTGAATTGAGGCCTTGAGGAATGAAGCTTTGATGGAAAAGAATGCTTTGTTTCCAGCCCCCTTCCCACACTTTTCGTGTCTTAACCACTGCCTTCCTGGCCCTTGGAGCCACCGTGTCTGTGTTACATTTTGTTATAGAAAACTAGCTTTGGAGTTCTGATCGTTCAAGAGAATGATTAAATATATATTTCCT
>NM_001253849.2
ctggtaatctgtggcgtaacaagacctccaggtgattctCTGTATTAGCAGCCGCTCTGTGCTCCCTGATTCCTCCAGAAAAGCACAAGGATTTAATCCAGATAGATATAAATTTCACCTGGGATCATTTATCATTCCACATTCTTCTTTAAGAAATGTGCTAAAGAGCCACAGATGGGTCTTGATGAAAACAAAGGAAAAGCCATGAAGTTTCTACAGCATAATTAGCATCATCATTATTCTGGCTGGAGCAATTGCACTCATCATTGGCTTTGGTATTTCAGGGAGACACTCCATCACAGTCACTACTGTCGCCTCAGCTGGGAACATTGGGGAGGATGGAATCCTGAGCTGCACTTTTGAACCTGACATCAAACTTTCTGATATCGTGATACAATGGCTGAAGGAAGGTGTTTTAGGCTTGGTCCATGAGTTCAAAGAAGGCAAAGATGAGCTGTCGGAGCAGGATGAAATGTTCAGAGGCCGGACAGCAGTGTTTGCTGATCAAGTGATAGTTGGCAATGCCTCTTTGCGGCTGAAAAACGTGCAACTCACAGATGCTGGCACCTACAAATGTTATATCATCACTTCTAAAGGCAAGGGGAATGCTAACCTTGAGTATAAAACTGGAGCCTTCAGCATGCCGGAAGTGAATGTGGACTATAATGCCAGCTCAGAGACCTTGCGGTGTGAGGCTCCCCGATGGTTCCCCCAGCCCACAGTGGTCTGGGCATCCCAAGTTGACCAGGGAGCCAACTTCTCGGAAGTCTCCAATACCAGCTTTGAGCTGAACTCTGAGAATGTGACCATGAAGGTTGTGTCTGTGCTCTACAATGTTACGATCAACAACACATACTCCTGTATGATTGAAAATGACATTGCCAAAGCAACAGGGGATATCAAAGTGACAGAATCGGAGATCAAAAGGCGGAGTCACCTACAGCTGCTAAACTCAAAGGCTTCTCTGTGTGTCTCTTCTTTCTTTGCCATCAGCTGGGCACTTCTGCCTCTCAGCCCTTACCTGATGCTAAAATAATGTGCCTCGGCCACAAAAAAGCATGCAAAGTCATTGTTACAACAGGGATCTACAGAACTATTTCACCACCAGATATGACCTAGTTTTATATTTCTGGGAGGAAATGAATTCATATCTAGAAGTCTGGAGTGAGCAAACAAGAGCAAGAAACAAAAAGAAGCCAAAAGCAGAAGGCTCCAATATGAACAAGATAAATCTATCTTCAAAGACATATTAGAAGTTGGGAAAATAATTCATGTGAACTAGACAAGTGTGTTAAGAGTGATAAGTAAAATGCACGTGGAGACAAGTGCATCCCCAGATCTCAGGGACCTCCCCCTGCCTGTCACCTGGGGAGTGAGAGGACAGGATAGTGCATGTTCTTTGTCTCTGAATTTTTAGTTATATGTGCTGTAATGTTGCTCTGAGGAAGCCCCTGGAAAGTCTATCCCAACATATCCACATCTTATATTCCACAAATTAAGCTGTAGTATGTACCCTAAGAcgctgctaattgactgccacttcgcaactcaggggcggctgcattttagtaatgggtcaaatgattcactttttatgatgcttccaaaggtgccttggCTTCTCTTCCCAACTGACAAATGCCAAAGTTGAGAAAAATGATCATAATTTTAGCATAAACAGAGCAGTCGGCGACACCGATTTTATAAATAAACTGAGCACCTTCTTTTTAAACAAACAAATGCGGGTTTATTTCTCAGATGATGTTCATCCGTGAATGGTCCAGGGAAGGACCTTTCACCTTGTCTATATGGCATTATGTCATCACAAGCTCTGAGGCTTCTCCTTTCCATCCTGCGTGGACAGCTAAGACCTCAGTTTTCAATAGCATCTAGAGcagtgggactcagctggggtgatttcgccccccatctccgggggaatgtctgaagacaattttggttacctcaatgagggagtggaggaggatacagtgctactaccaactagtggatagaggccagggatgctgctcaacctcctaccatgtacaggacgtctccccattacaactacccaatccgaagtgtcaactgtgtcagggctaagaaaccctgGTTTTGAGTAGAAAAGGGCCTGGAAAGAGGGGAGCCAACAAATCTGTCTGCTTCCTCACATTAGTCATTGGCAAATAAGCATTCTGTCTCTTTGGCTGCTGCCTCAGCACAGAGAGCCAGAACTCTATCGGGCACCAGGATAACATCTCTCAGTGAACAGAGTTGACAAGGCCTATGGGAAATGCCTGATGGGATTATCTTCAGCTTGTTGAGCTTCTAAGTTTCTTTCCCTTCATTCTACCCTGCAAGCCAAGTTCTGTAAGAGAAATGCCTGAGTTCTAGCTCAGGTTTTCTTACTCTGAATTTAGATCTCCAGACCCTGCCTGGCCACAATTCAAATTAAGGCAACAAACATATACCTTCCATGAAGCACACACAGACTTTTGAAAGCAAGGACAATGACTGCTTGAATTGAGGCCTTGAGGAATGAAGCTTTGAAGGAAAAGAATACTTTGTTTCCAGCCCCCTTCCCACACTCTTCATGTGTTAACCACTGCCTTCCTGGACCTTGGAGCCACGGTGACTGTATTACATGTTGTTATAGAAAACTGATTTTAGAGTTCTGATCGTTCAAGAGAATGATTAAATATACATTTCCTACACCA

Publications

PMID - Link Title