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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RARRES2P11
Plot displaying the genomic locations of a retrocopy (in chr20) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr20:29427315-29427811  UCSC
Coordinates (T2T) chr20:31056998-31057494  UCSC
Strand -
Parental Sequence NM_002889.4
Parental seq. overlap 420 bp
Parental seq. overlap (%) 60.2%
Genomic Region Intergenic
Retrocopy Summary RARRES2P11, located on chr20:29427315-29427811, is a retrocopy of the parental gene RARRES2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RARRES2
Full Name retinoic acid receptor responder 2
Also known as HP10433|TIG2
Coordinate chr7:150338329-150341685
Strand -
Gene summary This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine and as an antimicrobial protein with activity against bacteria and fungi. [provided by RefSeq, Nov 2014]

Homology

Species Scientific Name Retrocopy
Gibbon Nomascus leucogenys RARRES2P1
Crab-eating macaque Macaca fascicularis RARRES2P1
Marmoset Callithrix jacchus RARRES2P2
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RARRES2P11
CCAGCGCCGGGGCCTGCAGGTGGTCCTGGAGGAATCTGCAAGCACCTGCCCGTGCAGCGGGCCTTCCAGGAGACCAGTGTGGACAGCGCCCTGGACACGCCCTTCCCAGCTGGAACATTTGTGAGGCTGGAATTTAAGCTCCGGCAGACAGAGAAGTGGCCGGAGGAAAGACTGTAAAAACCCAAGTGCAAAGTCCAGCCTGAGAGGAGGAAGCAGGAATGGCTGACCTGCGTCAAACTGGGCTGTGAGGATAAGGTTCTGGGCAGGATGGTTCGCTGCCGTCCAGAGAAGCAGACTCGGCGGGAGCCTGAGGAGCACCAGGAGGCCGGGTGCAGCCGGGCGGAGCGGGCGGTGAGGACCCCACAGCTGCTGCTTCCCTGCACAGTTCGTCTTCTCCAAGGCCCGGCCCCCAGCGGAGCCCAGCACTGAATCGCATGGCGCCCCCTGGAGCCCTGGCGGGGATAACCAGTGGAAGACCCACCTCCCAGGGAGAGGAC
>NM_002889.4
AAGATTTCAGCTGCGGGACGGTCAGGGGAGACCTCCAGGCGCAGGGAAGGACGGCCAGGGTGACACGGAAGCATGCGACGGCTGCTGATCCCTCTGGCCCTGTGGCTGGGTGCGGTGGGCGTGGGCGTCGCCGAGCTCACGGAAGCCCAGCGCCGGGGCCTGCAGGTGGCCCTGGAGGAATTTCACAAGCACCCGCCCGTGCAGTGGGCCTTCCAGGAGACCAGTGTGGAGAGCGCCGTGGACACGCCCTTCCCAGCTGGAATATTTGTGAGGCTGGAATTTAAGCTGCAGCAGACAAGCTGCCGGAAGAGGGACTGGAAGAAACCCGAGTGCAAAGTCAGGCCCAATGGGAGGAAACGGAAATGCCTGGCCTGCATCAAACTGGGCTCTGAGGACAAAGTTCTGGGCCGGTTGGTCCACTGCCCCATAGAGACCCAAGTTCTGCGGGAGGCTGAGGAGCACCAGGAGACCCAGTGCCTCAGGGTGCAGCGGGCTGGTGAGGACCCCCACAGCTTCTACTTCCCTGGACAGTTCGCCTTCTCCAAGGCCCTGCCCCGCAGCTAAGCCAGCACTGAGATGCGTGGTGCCTCCAGGACCGCTGCGGGTGGTAACCAGTGGAAGACCCCAGCCCCCAGGGAGAGGAACCCGTTCTATCCCCAGCCATGATAATAAAGCTGCTCTCCCA

Publications

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