Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name ADI1P1
Plot displaying the genomic locations of a retrocopy (in chr20) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr20:41331165-41331437  UCSC
Coordinates (T2T) chr20:43062997-43063269  UCSC
Coordinates (hg19) chr20:39959805-39960077  UCSC
Strand +
Parental Sequence NM_018269.4_2
Parental seq. overlap 231 bp
Parental seq. overlap (%) 10.6%
Genomic Region Intergenic
Retrocopy Summary ADI1P1, located on chr20:41331165-41331437, is a retrocopy of the parental gene ADI1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ADI1
Full Name acireductone dioxygenase 1
Also known as APL1|ARD|ARD'|Fe-ARD|HMFT1638|MTCBP1|Ni-ARD|SIPL|mtnD
Coordinate chr2:3497366-3519531
Strand -
Gene summary This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ADI1P2
Bonobo Pan paniscus ADI1P2
Gorilla Gorilla gorilla ADI1P2
Orangutan Pongo abelii ADI1P2
Gibbon Nomascus leucogenys ADI1P1
Green monkey Chlorocebus sabaeus ADI1P1
Crab-eating macaque Macaca fascicularis ADI1P2
Rhesus Macaca mulatta ADI1P2
Baboon Papio anubis ADI1P2
Golden snub-nosed monkey Rhinopithecus roxellana ADI1P3
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ADI1P1
AGGCAGCCCCACCACCCCGAGCCCCTGGCCACCCAGTGGGCCAGAAACAGCCATGCTGGCTCAGGGTGCACTACTAAAGCTGGACACTGACAAATGAGAGAATGATCCAGAATTAGAAAAGACTCAAAGAGAGAGAAGCTACTCCTGGATAGACATAATAACCATATGTAAAGATAAATTACCAAATTATGAAGAAAAGATTAAGGTGTTTTATGGGGAGCATTTACACTTGGATGATCGGATCTGTTACATCCCGGGTGGCAGTGGATACTT
>NM_018269.4_2
GAGCGCGGCCCCTGGGTTCGAACACGGCACCCGCACTGCGCGTCATGGTGCAGGCCTGGTATATGGACGACGCCCCGGGCGACCCGCGGCAACCCCACCGCCCCGACCCCGGCCGCCCAGTGGGCCTGGAGCAGCTGCGGCGGCTCGGGGTGCTCTACTGGAAGCTGGATGCTGACAAATATGAGAATGATCCAGAATTAGAAAAGATCCGAAGAGAGAGGAACTACTCCTGGATGGACATCATAACCATATGCAAAGATAAACTACCAAATTATGAAGAAAAGATTAAGATGTTCTACGAGGAGCATTTGCACTTGGACGATGAGATCCGCTACATCCTGGATGGCAGTGGGTACTTCGATGTGAGGGACAAGGAGGACCAGTGGATCCGGATCTTCATGGAGAAGGGAGACATGGTGACGCTCCCCGCGGGGATCTATCACCGCTTCACGGTGGACGAGAAGAACTACACGAAGGCCATGCGGCTGTTTGTGGGAGAACCGGTGTGGACAGCGTACAACCGGCCCGCTGACCATTTTGAAGCCCGCGGGCAGTACGTGAAATTTCTGGCACAGACCGCCTAGCAGTGCTGCCTGGGAACTAACACGTGCCTCGTAAAGGTCCCCAATGTAATGACTGAGCAGAAAATCAATCACTTTCTCTTTGCTTTTAGAGGATAGCCTTGAGGCTAGATTATCTTTCCTTTGTAAGATTATTTGATCAGAATATTTTGTAATGAAAGGATCTAGAAAGCAACTTGGAAGTGTAAAGAGTCACCTTCATTTTCTGTAACTCAATCAAGACTGGTGGGTCCATGGCCCTGTGTTAGTTCATGCATTCAGTTGAGTCCCAAATGAAAGTTTCATCTCCCGAAATGCAGTTCCTTAGATGCCCATCTGGACGTGATGCCGCGCCTGCCGTGTAAGAAGGTGCAATCCTAGATAACACAGCTAGCCAGATAGAAGACACTTTTTTCTCCAAAATGATGCCTTGGGGTGGGGAGTGGTAGGGGGAAGAGCTCCCACCCTAAGGGGCACACACTGAGTTGCTTATGCCACTTCCTTGTTCAAAATAAAGTAACTGCCTTAATCTTATACTCATGGCTTGGAGTTACCTTATATTCAGGTATATGTGATATTTTGCCTGGTTTGTTAAAATTGCCCCATTTAGATTCCTTCTATAATTGTTCTTATAGATAAGTAATTTATATATGAGCTGTGTTAGTATTTTTTCAGTGTGAGATCTCTGGATTCTTTCACAATAAAGCTGTTGAATTTTAACAGGAGTATTAGTACATAAATTTTCTACTCAACAATTCCGAGATAGGATTATGCCTAGTTTGTCATATCACAGAAAAACTCCAAGTTAACTTCATGTTTTGGAAGGGCAGGTCGTTTTTAAAGTATTTCTTTTTTTAACTGGATGAAAAATCTTCATGTTAGGATTAATTTTCTTAATCACCTCCACACTGTACAGAGGAAACTCAAGCCTTAAATGTTTAAGTAAACTCTGTCTCAGTTTTAGGATTAAAATACCCACCGGTGGTGTGATGATGCCATATACCGCAGGGCTTGCTTCTGTCAAGTGTGACTCTATCTCAGTAATTAAAATAAGTGCTGATCTACTGATTTTTTTTAATGGATTCATTTCTAAATGGGCATTATAAATAGAGCTTGTTCATTTTTAAGAACGAAACATTCATATGATAAACTATCGCTTTAAATTGCCTTTCTTGCTTCATATAACTTTTCCCTGTCAGGATCCTTAGTGTTTGAAACTCCTCGTGCGGGGCTGGCCTCCTGCGGACTCTAGTTTCGCCTCCTTGATGTGGCGCCTGGGATTTCTTCACTTCAGAGCTGTATTTTTACAGGCAAGAGTAAGTTCctgggcacagtggctcatgcctgtaatctcagctactcaggaggctaaggtgggaggattcttagagcctgggaggtcgaggctgcagtgagctgtgattgtggccactgcactccagcctgggtgacagagcgagactctgtctcaaaaaagaagaaagaGTAAGAGCTGAGGCATATAATAGAATTCTGCTAAAGCACTTAAGGTGAAATCACATTTTCTTTTCCCAGGATGTTGCTCACATCTTTCGTTtttattgaggtgtcatttatatacaataaaatgtactcattttca

Publications

PMID - Link Title