RCPedia: Rtcs

Summary

Retrocopy Name	XIAPP3	Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr2:112853109-112856572 UCSC
Coordinates (T2T)	chr2:113279611-113283074 UCSC
Coordinates (hg19)	chr2:113610686-113614149 UCSC
Strand	+
Parental Sequence	NM_001378591.1
Parental seq. overlap	2482 bp
Parental seq. overlap (%)	29%
Genomic Region	Intergenic
Retrocopy Summary	XIAPP3, located on chr2:112853109-112856572, is a retrocopy of the parental gene XIAP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	XIAP
Full Name	X-linked inhibitor of apoptosis
Also known as	API3\|BIRC4\|IAP-3\|ILP1\|MIHA\|XLP2\|hIAP-3\|hIAP3
Coordinate	chrX:123859708-123913972
Strand	+
Gene summary	This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	XIAPP1
Bonobo	Pan paniscus	XIAPP1
Gorilla	Gorilla gorilla	XIAPP1
Orangutan	Pongo abelii	XIAPP1
Gibbon	Nomascus leucogenys	XIAPP1
Crab-eating macaque	Macaca fascicularis	XIAPP1
Rhesus	Macaca mulatta	XIAPP1
Baboon	Papio anubis	XIAPP2
Golden snub-nosed monkey	Rhinopithecus roxellana	XIAPP2
Green monkey	Chlorocebus sabaeus	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>XIAPP3
GCTGCCCCCTTCTGGGTTGGGGAAGTGGCAGGACCTTGGCAGCACCCCGAGCCGGCATGGCGCTAATAATGGAGGGATGCCAGACCCAAGTGGCTAAGGCCCGGCTGCAGAGCCAAGTTGGCATTTCCAGACTGGGGCTCGGGCCGCACCCTCTCCAGGACCCTCCCCTTGTACCGAGCAGATTGTCGCGGGCAGTTTGGGCCAGCTGTCCTGGCGTGGAATTTCCCAAATTCAACAAATCCTCCAAGAAATCAGTGGCAGATTATGAAGCATGGATCATTACTTTTGGGATGTGGATATATTCAGTTAACAAGGAGCAGCTTTCAAGAGCTGGATTTTATGCTTTAGGTGAAGGTGATAAAGTAAAGTGCTTTCACTGTGGAGGGGGGCTAACTGATTGGAAGCCCAGCGAAGACCCTTGGGAACAACATGATAAATGGCATCCAGGGTGTAAATATCTGTTAGAACAGAAGACACGAAAATATATAAACAATATTCATTTATCCCATTCACTTGAGGAGTGTCTGGTAAGAACTGCTGAAAAAACGCCATCACTAACTAGAAAAATTGATACCATCTTCCATAATCCTATGGTACAAGAAGCTATATGAATGGGGTTCAGTTTCAAAGACATTAAGAAAATAATGGAGGAAAAAATTCAGACATCTGGGAGCAACTGTAAATCACTTGAGGTTCTGATTGCAGATCCAGTGAAGGCTCAGAAAGACAGTACACAAGACGAATCAAGTCAGACTTCATTGCAGAAAGAGATTAGTACTGAAGAGCAGCTAAGACACCTGCAAGAGGAGAAGCTTTGCAAAATCTGTATGGATAGAAATATTGCTGTCGTTTTTATTCCTTGTGGACATCCAGTCACTCGTAAACAATGTGCTGAAGTGGTTGACAAATGTCTCAAGTGGTACGCAGTCATTACTTTCAAGCAAAAAAATTTTATGTCTTAATCTAACGCTATAGTAGGCATATTATGTTCGTATTATCCTGATTGAATGTGTGATGTGAACTGACTTTAAGTAATCAGGATTGAATTCCATTAGCATTTGCTACCAAGTAGGAAAAAAAAATGTAAATGGCAGTGTTTTAGTTGGCAATATAATCTTTGAATTTCTGGATTTTTCAGTTATTAGCTGTCTTATTTATCCAATTTTTTTTACTGTTATTTAATTGAAACCCTAGACTAAGAAGCATCATATTATAACTGATCACAATGTGTATTCATAGTATATTGACTTAATTTCTAAGTGTAAGTGAATTAATCATCTGAATTTTTTATTTTCAGATAGGCTTAACAAATAGAACATTCTGTATATAAATGTGTAGATTAGAGTTAATCTTTCCAATCACATAATTCGTTTTATGTGAAAAAGGAATGAACTGTTCCATGCTGGTGGAAAGATAGAGATTATTTTTAGAGGTTTGTCGTTGTGTTTTGGGATTCTGTTTTCTTTTAAAATTGTAAATATGTACTTGTGTGAATGATTTTTTAAAATGATTTTACCATTTTTGGAAGGGTATTTAATGATAGAATATCATCGAGCCAGCCAAATCAAAGCATGTATGTTTTTTATATGTGTACAACAAAAGGTTTGGAAAGATATGCACCAAATTGTTAAATGTGGTTTCACTTGAGGGGGTGGGAGGATGGGCCCCAGAGGGGTTTTTATAGGGGCCTTTCACTTGGTATTTTTTTCATTTTGTTCTGTTTGAAACTGTTTAAATTTTTTATAAGTATGTACTACTTTTGTAATCAGAATTATTAGAAAGCATTTTACTGATTTAAAAGCTTAGACATGTTCAAATGCCTGCAAAACTACTTAACACTCAGCTTTAGTTTTTCTAATCCAAAAAGGCCGGGCAGTTAATCTTTTTGGTGCCAATGTGAAATTTAAACGGTTTTATGTTTTTCCTGTGTTGTGAATGAAAAATATTTCTGAGTGGTGGTTTTTTGACAGGTAGACCATGTCTTGTCTTGTTTCAAAATAAGTATTTCTGATTTTGTAAAATGAAATATACAATATGTCACAGATCTTCCAATTAAGTAGTAAGGGTTTATCCTTAATCCTTGCTAATTTAAGCTTGCATAAGTCACTTTACTAAAAGATCTTTGTTAAGCTAGTATTTTAAACATCTGTCAGCTTATGTAGGTAAAAGTAGAAGCATGTTTGTACACTGTTGTAGTTATAGTGACAGCTTTCCATGTTGAGGTTCTCATATCACCTTGTATCTTGAAGTTTCATGTGAGTTTTTACCATTAGGATGATTAAGATGTATATAGGACAAAATATTAAGTCTTTCCTTTACCTAAGTTTGCTTTCTTGACTAGTAATAGTAGTAGATATTTCTGTAATAAATGTTCTCTCAAGATCCTTAAAATCTCTTGGAAATTATAAAAATATTGGAAAGAGAAGAACAGTTTTTAAATTTTAAAAACACTTGAATAAGAGTCAGTGTAAACTAGAAGTTTAAAAATGCTTCACAGAACACCCAGGGTTTACATTACAAGATTCTCACAACAAACCTATTGTAAAGGTGAGTAAGGCATGTTATTACAGAGAAAAGTTTGGGAGCAAAACTGTAAAAAATTATATTTTTGTTGTATTTTCTAAGAGAAAGAGTATTGTTATGTTCTCCTAACCTCTGTTGATTACTACTTTAAGTGATGTTCATTTAAAACATTGCAAATT

>NM_001378591.1
CTTACTGCCCCCATCCGGTTCGGGGAGGTGGCGGGACCTTGGCGGCGCCCGGAGCCGGCGTGGCGCTCATCGAGGGACGCCCGGCCCAAGTGGCTGGGGCCAAGCCGCAGAGCGGAGTTGGCATTTCCAGATTGGGGCTCGGGCCGCGCCTCCTCCGGGACCCTCCCCTTGGACCGAGCCGATCGCCGCGGGGCAGTTCGGGCCGGCTGTCCTGGCGCGAAAAGGTGGACAAGTCCTATTTTCAAGAGAAGATGACTTTTAACAGTTTTGAAGGATCTAAAACTTGTGTACCTGCAGACATCAATAAGGAAGAAGAATTTGTAGAAGAGTTTAATAGATTAAAAACTTTTGCTAATTTTCCAAGTGGTAGTCCTGTTTCAGCATCAACACTGGCACGAGCAGGGTTTCTTTATACTGGTGAAGGAGATACCGTGCGGTGCTTTAGTTGTCATGCAGCTGTAGATAGATGGCAATATGGAGACTCAGCAGTTGGAAGACACAGGAAAGTATCCCCAAATTGCAGATTTATCAACGGCTTTTATCTTGAAAATAGTGCCACGCAGTCTACAAATTCTGGTATCCAGAATGGTCAGTACAAAGTTGAAAACTATCTGGGAAGCAGAGATCATTTTGCCTTAGACAGGCCATCTGAGACACATGCAGACTATCTTTTGAGAACTGGGCAGGTTGTAGATATATCAGACACCATATACCCGAGGAACCCTGCCATGTATAGTGAAGAAGCTAGATTAAAGTCCTTTCAGAACTGGCCAGACTATGCTCACCTAACCCCAAGAGAGTTAGCAAGTGCTGGACTCTACTACACAGGTATTGGTGACCAAGTGCAGTGCTTTTGTTGTGGTGGAAAACTGAAAAATTGGGAACCTTGTGATCGTGCCTGGTCAGAACACAGGCGACACTTTCCTAATTGCTTCTTTGTTTTGGGCCGGAATCTTAATATTCGAAGTGAATCTGATGCTGTGAGTTCTGATAGGAATTTCCCAAATTCAACAAATCTTCCAAGAAATCCATCCATGGCAGATTATGAAGCACGGATCTTTACTTTTGGGACATGGATATACTCAGTTAACAAGGAGCAGCTTGCAAGAGCTGGATTTTATGCTTTAGGTGAAGGTGATAAAGTAAAGTGCTTTCACTGTGGAGGAGGGCTAACTGATTGGAAGCCCAGTGAAGACCCTTGGGAACAACATGCTAAATGGTATCCAGGGTGCAAATATCTGTTAGAACAGAAGGGACAAGAATATATAAACAATATTCATTTAACTCATTCACTTGAGGAGTGTCTGGTAAGAACTACTGAGAAAACACCATCACTAACTAGAAGAATTGATGATACCATCTTCCAAAATCCTATGGTACAAGAAGCTATACGAATGGGGTTCAGTTTCAAGGACATTAAGAAAATAATGGAGGAAAAAATTCAGATATCTGGGAGCAACTATAAATCACTTGAGGTTCTGGTTGCAGATCTAGTGAATGCTCAGAAAGACAGTATGCAAGATGAGTCAAGTCAGACTTCATTACAGAAAGAGATTAGTACTGAAGAGCAGCTAAGGCGCCTGCAAGAGGAGAAGCTTTGCAAAATCTGTATGGATAGAAATATTGCTATCGTTTTTGTTCCTTGTGGACATCTAGTCACTTGTAAACAATGTGCTGAAGCAGTTGACAAGTGTCCCATGTGCTACACAGTCATTACTTTCAAGCAAAAAATTTTTATGTCTTAATCTAACTCTATAGTAGGCATGTTATGTTGTTCTTATTACCCTGATTGAATGTGTGATGTGAACTGACTTTAAGTAATCAGGATTGAATTCCATTAGCATTTGCTACCAAGTAGGAAAAAAAATGTACATGGCAGTGTTTTAGTTGGCAATATAATCTTTGAATTTCTTGATTTTTCAGGGTATTAGCTGTATTATCCATTTTTTTTACTGTTATTTAATTGAAACCATAGACTAAGAATAAGAAGCATCATACTATAACTGAACACAATGTGTATTCATAGTATACTGATTTAATTTCTAAGTGTAAGTGAATTAATCATCTGGATTTTTTATTCTTTTCAGATAGGCTTAACAAATGGAGCTTTCTGTATATAAATGTGGAGATTAGAGTTAATCTCCCCAATCACATAATTTGTTTTGTGTGAAAAAGGAATAAATTGTTCCATGCTGGTGGAAAGATAGAGATTGTTTTTAGAGGTTGGTTGTTGTGTTTTAGGATTCTGTCCATTTTCTTTTAAAGTTATAAACACGTACTTGTGCGAATTATTTTTTTAAAGTGATTTGCCATTTTTGAAAGCGTATTTAATGATAgaatactatcgagccaacatgtactgacatggaaagatgtcaaagatatgttaagtgtaaaatgcaagtggcaaaacactatgtatagtctgagccagatcaaagtatgtatgtttttaatatgcatagaacaaaagatttggaaagatatacaccaaactgttaaatgtggtttctcttcggggagggggggattgggggaggggccccagaggggttttataggggccttttcactttctacttttttcattttgttctgttcgaattttttataagtatgtattacttttgtaatcagaaTTTTTAGAAAGTATTTTGCTGATTTAAAGGCTTAGGCATGTTCAAACGCCTGCAAAACTACTTATCACTCAGCTTTAGTTTTTCTAATCCAAGAAGGCAGGGCAGTTAACCTTTTTGGTGCCAATGTGAAATGTAAATGATTTTATGTTTTTCCTGCTTTGTGGATGAAAAATATTTCTGAGTGGTAGTTTTTTGACAGGTAGACCATGTCTTATCTTGTTTCAAAATAAGTATTTCTGATTTTGTAAAATGAAATATAAAATATGTCTCAGATCTTCCAATTAATTAGTAAGGATTCATCCTTAATCCTTGCTAGTTTAAGCCTGCCTAAGTCACTTTACTAAAAGATCTTTGTTAACTCAGTATTTTAAACATCTGTCAGCTTATGTAGGTAAAAGTAGAAGCATGTTTGTACACTGCTTGTAGTTATAGTGACAGCTTTCCATGTTGAGATTCTCATATCATCTTGTATCTTAAAGTTTCATGTGAGTTTTTACCGTTAGGATGATTAAGATGTATATAGGACAAAATGTTAAGTCTTTCCTCTACCTACATTTGTTTTCTTGGCTAGTAATAGTAGTAGATACTTCTGAAATAAATGTTCTCTCAAGATCCTTAAAACCTCTTGGAAATTATAAAAATATTGGCAAGAAAAGAAGAATAGTTGTTTAAATATTTTTTAAAAAACACTTGAATAAGAATCAGTAGGGTATAAACTAGAAGTTTAAAAATGCTTCATAGAACGTCCAGGGTTTACATTACAAGATTCTCACAACAAACCTATTGTAGAGGTGAGTAAGGCATGTTACTACAGAGGAAAGTTTGAGAGTAAAACTGTAAAAAATTATATTTTTGTTGTACTTTCTAAGAGAAAGAGTATTGTTATGTTCTCCTAACTTCTGTTGATTACTACTTTAAGTGATATTCATTTAAAACATTGCAAAtttattttatttatttaattttctttttgagatggagtcttgcttgtcacccaggctggagtgcagtggagtgatctctgctcactgcaacctccgccttctgggttcaagcgattctcgtgcctcagcttcctgagtagctggaattacaggcaggtgccaccatgcccgactaatttttttttatttttagtagagacggggtttcaccatgttggccaggctggtatcaaactcctgacctcaagagatccactcgccttgccctcccaaagtgctgggattacaggcttgagccaccacgcccggcTAAAACATTGCAAATTTAAATGAGAGTTTTAAAAATTAAATAATGACTGCCCTGTTTCTGTTTTAGTATGTAAATCCTCAGTTCTTCACCTTTGCACTGTCTGCCACTTAGTTTGGTTATATAGTCATTAACTTGAATTTGGTCTGTATAGTCTAGACTTTAAATTTAAAGTTTTCTACAAGGGGAGAAAAGTGTTAAAATTTTTAAAATATGTTTTCCAGGACACTTCACTTCCAAGTCAGGTAGGTAGTTCAATCTAGTTGTTAGCCAAGGACTCAAGGACTGAATTGTTTTAACATAAGGCTTTTCCTGTTCTGGGAGCCGCACTTCATTAAAATTCTTCTAAAACTTGTATGTTTAGAGTTAAGCAAGACTTTTTTTCTTCCTCTCCATGAGTTGTGAAATTTAATGCACAACGCTGATGTGGCTAACAAGTTTATTTTAAGAATTGTTTAGAAATGCTGTTGCTTCAGGTTCTTAAAATCACTCAGCACTCCAACTTCTAATCAAATTTTTGGAGACTTAACAGCATTTGTCTGTGTTTGAACTATAAAAAGCACCGGATCTTTTCCATCTAATTCCGCAAAAATTGATCATTTGCAAAGTCAAAACTATAGCCATATCCAAATCTTTTCCCCCTCCCAAGAGTTCTCAGTGTCTACATGTAGACTATTCCTTTTCTGTATAAAGTTCACTCTAGGATTTCAAGTCACCACTTATTTTACATTTTAGTCATGCAAAGATTCAAGTAGTTTTGCAATAAGTACTTATCTTTATTTGTAATAATTTAGTCTGCTGATCAAAAGCATTGTCTTAATTTTTGAGAACTGGTTTTAGCATTTACAAACTAAATTCCAGTTAATTAATTAATAGCTTTATATTGCCTTTCCTGCTACATTTGGTTTTTTCCCCTGTCCCTTTGATTACGGGCTAAGGTAGGGTAGAGTGGGTGTAGTGAGTGTATATAATGTGATTTGGCCCTGTGtattatgatattttgttatttttgttgttatattattTACATTTCAGTAGTTGTTTTTTGTGTTTCCATTTTAGTGGATAAAATTTGTATTTTGAACTATGAATGGAGACTACCGCCCCAGCATTAGTTTCACATGATATACCCTTTAAACCCGAATCATTGTTTTATTTCCTGATTACACAGGTGTTGAATGGGGAAAGGGGCTAGTATATCAGTAGGATATACTATGGGATGTATATATATCATTGCTGTTAGAGAAATGAAATAAAATGGggctgggctcagtggctcacgcctgtaatcccagcactttgggaggctgaggcaggtggatcacgaggtcaggagatcgagaccatcctggctaacacggtgaaaccccgtctctactaaaaaacagaaaattagccgggcgtggtggcgggcgcctgtagtcccagctactcgggaggctgaggcaggagaatggtgtgaacccgggaggcagagcttgcagtgagccgagatctcgccactgcactccagcctgggcaacagagcaagactctgtctcaaaaaaaaaaaaaaaagaaataagaaaaTGGGAAGCAATATTTGACATAGTTCTTTTTAGTCAAATCTACTTGTTAAAAAAAGGGTAGcagtttattcatctgtgaaaggaaaataatacttatcttacaaggttgcaagagctcaaggagaccatgtatgtaaagttcctgctgtaaatatgaactcccatcctaatACCCTTTTACCTCTCTGTGGGTTTGTCTTGACCTGGAAATTTGGGCTAAAACTTAGAAAAAATTCTTACATGATAACTCAGTGATGCTTACTCATAGTTTTTGGTGTTTCTCatagataagatataaatcagctgggcgcggtggctcatgcctgtaatcccagcactttgggaggccgaggcgggcagatcacctgaggtcgggaggtcgagaccagcctgaccaacatggagaaaccccgtctctactaaaaatacaaaattagctgggcgtggtggctcatgcctgtaatcccagctacttgggaggctgaggcaggagaatcgcttgaacccaggaggcggaggttgtggtgagcgaagatcgtgccattgcactccagcctgggcaacaagagcaaaactctgtctcaaaaaaaaaaaaagatataaatcacaataaataaataGGTCaatacaaatgttagccaggcgtggtggcacatgcccatagtcgcagctactctggaggcagaggcaggaggatcacttgagcccatgaatttgaggcagcagtgagctatgattgtgccactgtactccagtctgggtgacagagtgagaccccatctctaaataaaTAGGTCAAACCCTTAAAAATATTTAAATTCTTAAAAAATTGAAAAGATTATTCTTCTCAAATTTAGTTGAGCTTTCTAAGAGAAGCAATTGGCTTTTTCCCACTTCAATAATCATTTTCAGTTTGACTCATACAGTTAACACAATGTGAATTTCTTCCTCAGCataacagagttatagaatgacagggctggaagtgaccttagagagtatccagttctttcattttacaggtgaggcaactgagactcaaaggtgatgtaatttgtgcaaagattatagctaattagtagcagagccctgactgggacatagTTTGAAGGTGAAAAACTTCACCAAGCTACCTTTCTTGAAAGGTCCAAATGTTTATGTTTTCAACTACTCTTTCCACTGTACCATAACTTTCACTACATATTAAATGACACTTTATAACTAATATAATAGGACAATCATCAATGCATATATagccagcccttcatatctgtgggttttgcatccatggattcaaccaaggaggaattgaaaacactgagaaaaaaaaaAAAGACCACACaataaaaaaaaaaaatacaaaataatacaaagaaaaaGCCAAAATTGTCATACTGTTGTtaagcaacagtataacaactatttacatagcattAAGGTTGGTGCAAAAATGCAAAAAAAAAAAAAGCAATTATTTTTAAACCAACCTAAtatattgtattaggtattaaagtcatctggacatgaattaaagtatatgATGccagcctggacaaaaggcaaaaccctgtctctacaaaaaatacaaaaattagctgggcatggtggtgtgtgcctgtagtcctggctactccggagcctgaggtgggaggatcgcttgagtctgggaggcagaggctgcattgagctatgatcatggcactgcattccagcctgggtgacagtgcaagaccttgtctcagaataaataaaGTATGTGATGAAGATGTGCATACATTATATGCAAATACTGttttttttttttttaatttaaacagtctcactgtgttgcccaggatggagtgcaatggcacaatcttggctcatggcaaactctgcctcgcaagcagctgggactacaggcatgctccacggtgcccagttaattttttttgtattcttagtagagacagggtttcaccatgttggccaggctagtcttgaatttctgacctcaagtgattcatctcccaaagtgctgggattacaggcgtgagccaccacggccggctaatttttgtattttttagtagtgactggtttcgcggtgttgaccaggctggtctcgaactcctgatctcaggtgatctgcctgcctcggcctcacaaagtgctgggattacaggtgtgaaccactgctcccggccTTGTGTGattttatctaagggacttaagcgtcctcaggtcctagggggtcgtgaaaccaaaaccccagggatagcaagggacaattgTATCTTCAAAGTAGACAAATGGCgccgggcacggtggctcacgcctgtaatcccagcagtttccgaggctgaggcaggcggctcacctgaggtcaggagttggagaccagcctggccaacatgctgaaaccctgtctgtacaaaaatacaaaaatagctgggcatggtggcgcatgcctgtagtcccagctactagagcgactgaggcaggagaattgcttgaacctgggaggcggaggttgcagggagccaagatggcgccaccgcactccagcctaggtgatagagtgagactccctctcaaaaacaaaacaaaacaaaaaaaTTAGACAAATGCTACATTAATGTTTGGGTGGTCAGATTCTACTTTGAATCTGAAGTTTGCAGATATGCCTATAGATTTTTGGAGTTTACCACTTTCTTATTCTGTATCATTAATGTAATATTTTAAATTACTATATATGTTACCATTTTTCTGGATTTAGTAAGAAATTTGCAGTTTTGGTTTGATGTAACAAGGGTTTTAATGTAATTTATGTTAGATTTTGCATTTTTTTCATTACTGTTATATTTTAACCTGACTGACTGATCTAATTGTATTAGTATTGTGAATAATCATGTGAAATGTTTTGAGACAGAGTACTATATTTGTGAATATAATTTTATGGTTTTTTTCACTTAGAACCTTTCTGTGTGGAAAACTAAGAAAATTGCTTTCTGCTGTATAATCTGGCATTCATTGTAGATTAAAGCTTATTTTTCTGTGAATAAAACGTATTCAATAAAATACTATTCTTTAAAATTA

>NM_001378591.1 

CTTACTGCCCCCATCCGGTTCGGGGAGGTGGCGGGACCTTGGCGGCGCCCGGAGCCGGCGTGGCGCTCATCGAGGGACGCCCGGCCCAAGTGGCTGGGGCCAAGCCGCAGAGCGGAGTTGGCATTTCCAGATTGGGGCTCGGGCCGCGCCTCCTCCGGGACCCTCCCCTTGGACCGAGCCGATCGCCGCGGGGCAGTTCGGGCCGGCTGTCCTGGCGCGAAAAGGTGGACAAGTCCTATTTTCAAGAGAAGATGACTTTTAACAGTTTTGAAGGATCTAAAACTTGTGTACCTGCAGACATCAATAAGGAAGAAGAATTTGTAGAAGAGTTTAATAGATTAAAAACTTTTGCTAATTTTCCAAGTGGTAGTCCTGTTTCAGCATCAACACTGGCACGAGCAGGGTTTCTTTATACTGGTGAAGGAGATACCGTGCGGTGCTTTAGTTGTCATGCAGCTGTAGATAGATGGCAATATGGAGACTCAGCAGTTGGAAGACACAGGAAAGTATCCCCAAATTGCAGATTTATCAACGGCTTTTATCTTGAAAATAGTGCCACGCAGTCTACAAATTCTGGTATCCAGAATGGTCAGTACAAAGTTGAAAACTATCTGGGAAGCAGAGATCATTTTGCCTTAGACAGGCCATCTGAGACACATGCAGACTATCTTTTGAGAACTGGGCAGGTTGTAGATATATCAGACACCATATACCCGAGGAACCCTGCCATGTATAGTGAAGAAGCTAGATTAAAGTCCTTTCAGAACTGGCCAGACTATGCTCACCTAACCCCAAGAGAGTTAGCAAGTGCTGGACTCTACTACACAGGTATTGGTGACCAAGTGCAGTGCTTTTGTTGTGGTGGAAAACTGAAAAATTGGGAACCTTGTGATCGTGCCTGGTCAGAACACAGGCGACACTTTCCTAATTGCTTCTTTGTTTTGGGCCGGAATCTTAATATTCGAAGTGAATCTGATGCTGTGAGTTCTGATAGGAATTTCCCAAATTCAACAAATCTTCCAAGAAATCCATCCATGGCAGATTATGAAGCACGGATCTTTACTTTTGGGACATGGATATACTCAGTTAACAAGGAGCAGCTTGCAAGAGCTGGATTTTATGCTTTAGGTGAAGGTGATAAAGTAAAGTGCTTTCACTGTGGAGGAGGGCTAACTGATTGGAAGCCCAGTGAAGACCCTTGGGAACAACATGCTAAATGGTATCCAGGGTGCAAATATCTGTTAGAACAGAAGGGACAAGAATATATAAACAATATTCATTTAACTCATTCACTTGAGGAGTGTCTGGTAAGAACTACTGAGAAAACACCATCACTAACTAGAAGAATTGATGATACCATCTTCCAAAATCCTATGGTACAAGAAGCTATACGAATGGGGTTCAGTTTCAAGGACATTAAGAAAATAATGGAGGAAAAAATTCAGATATCTGGGAGCAACTATAAATCACTTGAGGTTCTGGTTGCAGATCTAGTGAATGCTCAGAAAGACAGTATGCAAGATGAGTCAAGTCAGACTTCATTACAGAAAGAGATTAGTACTGAAGAGCAGCTAAGGCGCCTGCAAGAGGAGAAGCTTTGCAAAATCTGTATGGATAGAAATATTGCTATCGTTTTTGTTCCTTGTGGACATCTAGTCACTTGTAAACAATGTGCTGAAGCAGTTGACAAGTGTCCCATGTGCTACACAGTCATTACTTTCAAGCAAAAAATTTTTATGTCTTAATCTAACTCTATAGTAGGCATGTTATGTTGTTCTTATTACCCTGATTGAATGTGTGATGTGAACTGACTTTAAGTAATCAGGATTGAATTCCATTAGCATTTGCTACCAAGTAGGAAAAAAAATGTACATGGCAGTGTTTTAGTTGGCAATATAATCTTTGAATTTCTTGATTTTTCAGGGTATTAGCTGTATTATCCATTTTTTTTACTGTTATTTAATTGAAACCATAGACTAAGAATAAGAAGCATCATACTATAACTGAACACAATGTGTATTCATAGTATACTGATTTAATTTCTAAGTGTAAGTGAATTAATCATCTGGATTTTTTATTCTTTTCAGATAGGCTTAACAAATGGAGCTTTCTGTATATAAATGTGGAGATTAGAGTTAATCTCCCCAATCACATAATTTGTTTTGTGTGAAAAAGGAATAAATTGTTCCATGCTGGTGGAAAGATAGAGATTGTTTTTAGAGGTTGGTTGTTGTGTTTTAGGATTCTGTCCATTTTCTTTTAAAGTTATAAACACGTACTTGTGCGAATTATTTTTTTAAAGTGATTTGCCATTTTTGAAAGCGTATTTAATGATAgaatactatcgagccaacatgtactgacatggaaagatgtcaaagatatgttaagtgtaaaatgcaagtggcaaaacactatgtatagtctgagccagatcaaagtatgtatgtttttaatatgcatagaacaaaagatttggaaagatatacaccaaactgttaaatgtggtttctcttcggggagggggggattgggggaggggccccagaggggttttataggggccttttcactttctacttttttcattttgttctgttcgaattttttataagtatgtattacttttgtaatcagaaTTTTTAGAAAGTATTTTGCTGATTTAAAGGCTTAGGCATGTTCAAACGCCTGCAAAACTACTTATCACTCAGCTTTAGTTTTTCTAATCCAAGAAGGCAGGGCAGTTAACCTTTTTGGTGCCAATGTGAAATGTAAATGATTTTATGTTTTTCCTGCTTTGTGGATGAAAAATATTTCTGAGTGGTAGTTTTTTGACAGGTAGACCATGTCTTATCTTGTTTCAAAATAAGTATTTCTGATTTTGTAAAATGAAATATAAAATATGTCTCAGATCTTCCAATTAATTAGTAAGGATTCATCCTTAATCCTTGCTAGTTTAAGCCTGCCTAAGTCACTTTACTAAAAGATCTTTGTTAACTCAGTATTTTAAACATCTGTCAGCTTATGTAGGTAAAAGTAGAAGCATGTTTGTACACTGCTTGTAGTTATAGTGACAGCTTTCCATGTTGAGATTCTCATATCATCTTGTATCTTAAAGTTTCATGTGAGTTTTTACCGTTAGGATGATTAAGATGTATATAGGACAAAATGTTAAGTCTTTCCTCTACCTACATTTGTTTTCTTGGCTAGTAATAGTAGTAGATACTTCTGAAATAAATGTTCTCTCAAGATCCTTAAAACCTCTTGGAAATTATAAAAATATTGGCAAGAAAAGAAGAATAGTTGTTTAAATATTTTTTAAAAAACACTTGAATAAGAATCAGTAGGGTATAAACTAGAAGTTTAAAAATGCTTCATAGAACGTCCAGGGTTTACATTACAAGATTCTCACAACAAACCTATTGTAGAGGTGAGTAAGGCATGTTACTACAGAGGAAAGTTTGAGAGTAAAACTGTAAAAAATTATATTTTTGTTGTACTTTCTAAGAGAAAGAGTATTGTTATGTTCTCCTAACTTCTGTTGATTACTACTTTAAGTGATATTCATTTAAAACATTGCAAAtttattttatttatttaattttctttttgagatggagtcttgcttgtcacccaggctggagtgcagtggagtgatctctgctcactgcaacctccgccttctgggttcaagcgattctcgtgcctcagcttcctgagtagctggaattacaggcaggtgccaccatgcccgactaatttttttttatttttagtagagacggggtttcaccatgttggccaggctggtatcaaactcctgacctcaagagatccactcgccttgccctcccaaagtgctgggattacaggcttgagccaccacgcccggcTAAAACATTGCAAATTTAAATGAGAGTTTTAAAAATTAAATAATGACTGCCCTGTTTCTGTTTTAGTATGTAAATCCTCAGTTCTTCACCTTTGCACTGTCTGCCACTTAGTTTGGTTATATAGTCATTAACTTGAATTTGGTCTGTATAGTCTAGACTTTAAATTTAAAGTTTTCTACAAGGGGAGAAAAGTGTTAAAATTTTTAAAATATGTTTTCCAGGACACTTCACTTCCAAGTCAGGTAGGTAGTTCAATCTAGTTGTTAGCCAAGGACTCAAGGACTGAATTGTTTTAACATAAGGCTTTTCCTGTTCTGGGAGCCGCACTTCATTAAAATTCTTCTAAAACTTGTATGTTTAGAGTTAAGCAAGACTTTTTTTCTTCCTCTCCATGAGTTGTGAAATTTAATGCACAACGCTGATGTGGCTAACAAGTTTATTTTAAGAATTGTTTAGAAATGCTGTTGCTTCAGGTTCTTAAAATCACTCAGCACTCCAACTTCTAATCAAATTTTTGGAGACTTAACAGCATTTGTCTGTGTTTGAACTATAAAAAGCACCGGATCTTTTCCATCTAATTCCGCAAAAATTGATCATTTGCAAAGTCAAAACTATAGCCATATCCAAATCTTTTCCCCCTCCCAAGAGTTCTCAGTGTCTACATGTAGACTATTCCTTTTCTGTATAAAGTTCACTCTAGGATTTCAAGTCACCACTTATTTTACATTTTAGTCATGCAAAGATTCAAGTAGTTTTGCAATAAGTACTTATCTTTATTTGTAATAATTTAGTCTGCTGATCAAAAGCATTGTCTTAATTTTTGAGAACTGGTTTTAGCATTTACAAACTAAATTCCAGTTAATTAATTAATAGCTTTATATTGCCTTTCCTGCTACATTTGGTTTTTTCCCCTGTCCCTTTGATTACGGGCTAAGGTAGGGTAGAGTGGGTGTAGTGAGTGTATATAATGTGATTTGGCCCTGTGtattatgatattttgttatttttgttgttatattattTACATTTCAGTAGTTGTTTTTTGTGTTTCCATTTTAGTGGATAAAATTTGTATTTTGAACTATGAATGGAGACTACCGCCCCAGCATTAGTTTCACATGATATACCCTTTAAACCCGAATCATTGTTTTATTTCCTGATTACACAGGTGTTGAATGGGGAAAGGGGCTAGTATATCAGTAGGATATACTATGGGATGTATATATATCATTGCTGTTAGAGAAATGAAATAAAATGGggctgggctcagtggctcacgcctgtaatcccagcactttgggaggctgaggcaggtggatcacgaggtcaggagatcgagaccatcctggctaacacggtgaaaccccgtctctactaaaaaacagaaaattagccgggcgtggtggcgggcgcctgtagtcccagctactcgggaggctgaggcaggagaatggtgtgaacccgggaggcagagcttgcagtgagccgagatctcgccactgcactccagcctgggcaacagagcaagactctgtctcaaaaaaaaaaaaaaaagaaataagaaaaTGGGAAGCAATATTTGACATAGTTCTTTTTAGTCAAATCTACTTGTTAAAAAAAGGGTAGcagtttattcatctgtgaaaggaaaataatacttatcttacaaggttgcaagagctcaaggagaccatgtatgtaaagttcctgctgtaaatatgaactcccatcctaatACCCTTTTACCTCTCTGTGGGTTTGTCTTGACCTGGAAATTTGGGCTAAAACTTAGAAAAAATTCTTACATGATAACTCAGTGATGCTTACTCATAGTTTTTGGTGTTTCTCatagataagatataaatcagctgggcgcggtggctcatgcctgtaatcccagcactttgggaggccgaggcgggcagatcacctgaggtcgggaggtcgagaccagcctgaccaacatggagaaaccccgtctctactaaaaatacaaaattagctgggcgtggtggctcatgcctgtaatcccagctacttgggaggctgaggcaggagaatcgcttgaacccaggaggcggaggttgtggtgagcgaagatcgtgccattgcactccagcctgggcaacaagagcaaaactctgtctcaaaaaaaaaaaaagatataaatcacaataaataaataGGTCaatacaaatgttagccaggcgtggtggcacatgcccatagtcgcagctactctggaggcagaggcaggaggatcacttgagcccatgaatttgaggcagcagtgagctatgattgtgccactgtactccagtctgggtgacagagtgagaccccatctctaaataaaTAGGTCAAACCCTTAAAAATATTTAAATTCTTAAAAAATTGAAAAGATTATTCTTCTCAAATTTAGTTGAGCTTTCTAAGAGAAGCAATTGGCTTTTTCCCACTTCAATAATCATTTTCAGTTTGACTCATACAGTTAACACAATGTGAATTTCTTCCTCAGCataacagagttatagaatgacagggctggaagtgaccttagagagtatccagttctttcattttacaggtgaggcaactgagactcaaaggtgatgtaatttgtgcaaagattatagctaattagtagcagagccctgactgggacatagTTTGAAGGTGAAAAACTTCACCAAGCTACCTTTCTTGAAAGGTCCAAATGTTTATGTTTTCAACTACTCTTTCCACTGTACCATAACTTTCACTACATATTAAATGACACTTTATAACTAATATAATAGGACAATCATCAATGCATATATagccagcccttcatatctgtgggttttgcatccatggattcaaccaaggaggaattgaaaacactgagaaaaaaaaaAAAGACCACACaataaaaaaaaaaaatacaaaataatacaaagaaaaaGCCAAAATTGTCATACTGTTGTtaagcaacagtataacaactatttacatagcattAAGGTTGGTGCAAAAATGCAAAAAAAAAAAAAGCAATTATTTTTAAACCAACCTAAtatattgtattaggtattaaagtcatctggacatgaattaaagtatatgATGccagcctggacaaaaggcaaaaccctgtctctacaaaaaatacaaaaattagctgggcatggtggtgtgtgcctgtagtcctggctactccggagcctgaggtgggaggatcgcttgagtctgggaggcagaggctgcattgagctatgatcatggcactgcattccagcctgggtgacagtgcaagaccttgtctcagaataaataaaGTATGTGATGAAGATGTGCATACATTATATGCAAATACTGttttttttttttttaatttaaacagtctcactgtgttgcccaggatggagtgcaatggcacaatcttggctcatggcaaactctgcctcgcaagcagctgggactacaggcatgctccacggtgcccagttaattttttttgtattcttagtagagacagggtttcaccatgttggccaggctagtcttgaatttctgacctcaagtgattcatctcccaaagtgctgggattacaggcgtgagccaccacggccggctaatttttgtattttttagtagtgactggtttcgcggtgttgaccaggctggtctcgaactcctgatctcaggtgatctgcctgcctcggcctcacaaagtgctgggattacaggtgtgaaccactgctcccggccTTGTGTGattttatctaagggacttaagcgtcctcaggtcctagggggtcgtgaaaccaaaaccccagggatagcaagggacaattgTATCTTCAAAGTAGACAAATGGCgccgggcacggtggctcacgcctgtaatcccagcagtttccgaggctgaggcaggcggctcacctgaggtcaggagttggagaccagcctggccaacatgctgaaaccctgtctgtacaaaaatacaaaaatagctgggcatggtggcgcatgcctgtagtcccagctactagagcgactgaggcaggagaattgcttgaacctgggaggcggaggttgcagggagccaagatggcgccaccgcactccagcctaggtgatagagtgagactccctctcaaaaacaaaacaaaacaaaaaaaTTAGACAAATGCTACATTAATGTTTGGGTGGTCAGATTCTACTTTGAATCTGAAGTTTGCAGATATGCCTATAGATTTTTGGAGTTTACCACTTTCTTATTCTGTATCATTAATGTAATATTTTAAATTACTATATATGTTACCATTTTTCTGGATTTAGTAAGAAATTTGCAGTTTTGGTTTGATGTAACAAGGGTTTTAATGTAATTTATGTTAGATTTTGCATTTTTTTCATTACTGTTATATTTTAACCTGACTGACTGATCTAATTGTATTAGTATTGTGAATAATCATGTGAAATGTTTTGAGACAGAGTACTATATTTGTGAATATAATTTTATGGTTTTTTTCACTTAGAACCTTTCTGTGTGGAAAACTAAGAAAATTGCTTTCTGCTGTATAATCTGGCATTCATTGTAGATTAAAGCTTATTTTTCTGTGAATAAAACGTATTCAATAAAATACTATTCTTTAAAATTA

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