Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name C1QBPP1
Plot displaying the genomic locations of a retrocopy (in chr21) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr21:19759119-19760020  UCSC
Coordinates (T2T) chr21:18119530-18120431  UCSC
Coordinates (hg19) chr21:21131433-21132334  UCSC
Strand -
Parental Sequence NM_001212.4
Parental seq. overlap 786 bp
Parental seq. overlap (%) 66.8%
Genomic Region Intergenic
Retrocopy Summary C1QBPP1, located on chr21:19759119-19760020, is a retrocopy of the parental gene C1QBP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name C1QBP
Full Name complement C1q binding protein
Also known as COXPD33|GC1QBP|HABP1|SF2AP32|SF2p32|gC1Q-R|gC1qR|p32
Coordinate chr17:5432777-5439155
Strand -
Gene summary The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes C1QBPP4
Bonobo Pan paniscus C1QBPP4
Gorilla Gorilla gorilla C1QBPP5
Orangutan Pongo abelii C1QBPP4
Gibbon Nomascus leucogenys C1QBPP4
Golden snub-nosed monkey Rhinopithecus roxellana C1QBPP3
Marmoset Callithrix jacchus C1QBPP6
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>C1QBPP1
GGCCTCCTGCGGCCTCGCAGGTCCTGCCCCAGTGGCTGTGGCGCGCTGCACACCGAAGGAGACTGTTGATATCCTGAATGGTGAAATTGAGGAGGAGAGGAAAATCCAGAAGCATAAAACCCTCCCTAAGATGTCTGGAGGATGGGAGCGGCAGTTAAATGGGACAGAAGCTAAATTAGTGGGAAAAGCTGCCGGGGAAAGATCGCTGTCACTTTCAACATTAACAACAGCATCCCACCGACACTTGATGGCAAGGAGGAACCCTCGAAAGGGCAGCAAGTTGGAGAACAGGAGCCTGAATTGACATCACCTCCCAATTTCGTGGTCCAAGTTTTGAAGAGTGGTGGCAAGAAGGCCCTTGTGCTGGACTGTCACTACCCAGAGGATGAGGGTGGGCCAGAAGAGGAGGTTGAGAGTGACCTTTTCTCTATCAGGGAAGTAACTTTCAGTCCAATGGGGAGTCTCAATGAAAGGACACTAATTTTATACTCAACACAGATTTCCGGGACTCGGCCTTATATGACCACCTAGTGGATTTCCTTGTGAATGGAGGGGTGGCCAACCCTTTTGCCCATAAGCTAATGGAGCTCAGCACAGCCCTGGAGGAGCAGGAGTACATGACTTTTCTTGAAGACCTCAGAAGTTCTGTCAAGAGCCAGTAGAACGGACAGACACTGAAAGCCATAGTTTTATGGCAGGCTTTGGCCGATGAACAAATCCTACCCTGAAGCCAGACACATGTGCTTTAAAATGATTGTCATCTTAATACCACTGGGAAAAATAGCAAATTTAAATTCTTTCTTTTGTGCTCCCATTTATTATCATTTGTTTTTTCTGTACAAATCTATTCTTTCTAGATTTTTATATAACACGATAGACAATAAAATGGGTTTGTCTCCTCA
>NM_001212.4
GCTTCCGGCGGCGCCTCAGGTCGCGGGGCGCCTAGGCCTGGGTTGTCCTTTGCATCTGCACGTGTTCGCAGTCGTTTCCGCGATGCTGCCTCTGCTGCGCTGCGTGCCCCGTGTGCTGGGCTCCTCCGTCGCCGGCCTCCGCGCTGCCGCGCCCGCCTCGCCTTTCCGGCAGCTCCTGCAGCCGGCACCCCGGCTGTGCACCCGGCCCTTCGGGCTGCTCAGCGTGCGCGCAGGTTCCGAGCGGCGGCCGGGCCTcctgcggcctcgcggaccctgcgcctgtggctgtggctgcggctcgctgcACACCGACGGAGACAAAGCTTTTGTTGATTTCCTGAGTGATGAAATTAAGGAGGAAAGAAAAATTCAGAAGCATAAAACCCTCCCTAAGATGTCTGGAGGTTGGGAGCTGGAACTGAATGGGACAGAAGCGAAATTAGTGCGGAAAGTTGCCGGGGAAAAAATCACGGTCACTTTCAACATTAACAACAGCATCCCACCAACATTTGATGGTGAGGAGGAACCCTCGCAAGGGCAGAAGGTTGAAGAACAGGAGCCTGAACTGACATCAACTCCCAATTTCGTGGTTGAAGTTATAAAGAATGATGATGGCAAGAAGGCCCTTGTGTTGGACTGTCATTATCCAGAGGATGAGGTTGGACAAGAAGACGAGGCTGAGAGTGACATCTTCTCTATCAGGGAAGTTAGCTTTCAGTCCACTGGCGAGTCTGAATGGAAGGATACTAATTATACACTCAACACAGATTCCTTGGACTGGGCCTTATATGACCACCTAATGGATTTCCTTGCCGACCGAGGGGTGGACAACACTTTTGCAGATGAGCTGGTGGAGCTCAGCACAGCCCTGGAGCACCAGGAGTACATTACTTTTCTTGAAGACCTCAAGAGTTTTGTCAAGAGCCAGTAGAGCAGACAGATGCTGAAAGCCATAGTTTCATGGCAGGCTTTGGCCAGTGAACAAATCCTACTCTGAAGCTAGACATGTGCTTTGAAATGATTATCATCCTAATATCATGGGGGAAAAAATACCAAATTTAAATTATATGTTTTGTGTTCTCATTTATTATCATTTTTTTCTGTACAAATCTATTATTTCTAGATTTTTGTATAACATGATAGACATAAAATTGGTTTATCTCCTCCAA

Publications

PMID - Link Title