RCPedia: Rtcs

Summary

Retrocopy Name	MAPK6P2	Plot displaying the genomic locations of a retrocopy (in chr21) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr21:22435045-22439040 UCSC
Coordinates (T2T)	chr21:20791802-20795797 UCSC
Coordinates (hg19)	chr21:23807365-23811360 UCSC
Strand	-
Parental Sequence	NM_002748.4
Parental seq. overlap	3591 bp
Parental seq. overlap (%)	66.8%
Genomic Region	Intergenic
Retrocopy Summary	MAPK6P2, located on chr21:22435045-22439040, is a retrocopy of the parental gene MAPK6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	MAPK6
Full Name	mitogen-activated protein kinase 6
Also known as	ERK3\|HsT17250\|PRKM6\|p97MAPK
Coordinate	chr15:52019219-52067375
Strand	+
Gene summary	The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	MAPK6P4
Bonobo	Pan paniscus	MAPK6P4
Gorilla	Gorilla gorilla	MAPK6P5
Orangutan	Pongo abelii	MAPK6P5
Gibbon	Nomascus leucogenys	MAPK6P3
Green monkey	Chlorocebus sabaeus	MAPK6P1
Crab-eating macaque	Macaca fascicularis	MAPK6P1
Rhesus	Macaca mulatta	MAPK6P1
Baboon	Papio anubis	LOC101003631P2
Golden snub-nosed monkey	Rhinopithecus roxellana	MAPK6P5
Marmoset	Callithrix jacchus	MAPK6P4
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>MAPK6P2
GCTGCTGCCAGTACAGCTGGAGACGTGAGCCCACGCTGGGGGCTGTCCATGGGCCCACACCCTCTCGATGAGTGGAAGTCCCGTTGGATCAGAGTAAGACGGACAGTAGCTTTGGTTGTGATTGTGGTGAGCCGGAGCCACCTGATCACTAACAAAAGACATCTGTTAACCAACAGCCGCCAGGGCTTTCTGGTGAAATATATAGCAACAAAGGAAGAAAAGAAACAAAATGGAAACAGTGCTTACCAGCACCTTAGAACAATGCTGCTCAGGGCCAGTCCAACACTGAATGTGTCTGCACTGTGAGGAGAATGTTCACAGAAGCCTGTTGCGTTGTGTGCATATTTATTCATATTTTTGTTAAATGTTAAATCATTTATCACAGTAAATCTGGGTGCATAGTACATAATTTCATTCCATTTGAGCTTCTTGAGTGTTTTATTTAAATGTCTGCAGAGCTGCTGCCCCTTTCTTGAACTATGAGTACTGCAATCTCTTAAATTCTCAATATGAGTAGAGCTTTTTGAGCTTTATATCTAAGGGGAACTGAACAAGCCTGTTTGGAAAATGCAATGAACATCAAGAAATCATCTTGCTGTGGAAGCATAATTATTTTTCTTCTGCCTGTATAAAAGATCTTTCCTTTTGATGTCAGTTTTCTTCCTTGTTTACACAAGTTCAACAATTCAAAAGGAAAACTTTTTTTTTCTGCTGTAGACGATGACTGTGATAAAAGAGAATCCATCAAGAAAATTCTCCTTACTGATCCCCAGAGTGTCAAAAATGCTCTACATGAAATCAAAATTATTAGAAGATTTGACATCGTGACATTGTGAAAGTGTTTGAAATTCCTAGTACCAGTGGAAGCCAATTAACAAACAATGTGAACTCTCTTACCAAACTTAACAGTATTTACATTTTTCAGAATTACATGGAGACAGACTTGGCTAATATGATGGAGGAGGGCCCTTTACTGGAAAAGCATGCCAGACTTTTCATGTATCAGCTGCTAACGTGGCTTAAGTATTCACTCTGCAAGTGTATTGCCCAGATATCTCAAACCAACTAATCTTTTCATTAATACTGAAGACATGATGCTGAAGATAGGGGACTTTTGTCTTGCACAAATCATGGATCCTCATTATTCCCATAAGGATCATCTCTCTGAAGGACTGGTAACTAAATGGTACAGATCTCCACATCTTTTACATTCTTCTAATAGTTATAGTAAAGCCATTGACATGTGGACTGCAGGCCACATCTTTGCTGAAATGCTGACTGGTAAAACCCTTTTTGCAGGTGCACGTGAACTCGAACAGATGCAGCTGATTTTAGAATCTAGTCCTGTTATACATGAGGAAGATCATCAGGAGCTTCTCAGTGTAATTCCAGTTTACATTAGAAATGAAATGACTGAACCACAGAAACCTTTAACTCAGCTGCTTCAGGGAATTAGCTGAGAAGCACTGGATCTCCTGGAACAAATTTTGACATTTATCCCTACAGATGGGTTAACAGCAGAAGAAGCGCTCTCCCATCATTACATGAGCATATATTATTTTCCAACGGATGAGCCAATTTCAAGTCATCTTTTTCATATTGAAGATGAAGTTTATGATATTTTGCTTATGGATGAAACTCACAGTCACATTTATAACTGGGAAAGGTATGATTGTTAGTTTTCAGTGCATGATTGGCCTATACATAACAACTTTGGTATTGATGAAGTTCTGCTTGACCTGAGAGCTCTGTCTGATATCACTGATGAAGAAGTACGAGTTGATCCCTGAAAATATTTGGATGGACATTCGGAAAAGCATAAAGTATCTGGAGGATCCAATTGCTCTACTGAGCCTTTTTGGCAGTACCCAGATCATCATAAAAACAAATAGGGATTTGAAGTGTAGTCATATTTGTAACTACAAAGCCAGGTCATCATCATATTTAGATAACTTAGTTTGGAGAGCGAGTGAAGTTAACCATTACTATGAACCCAAGGTTATTATAGATATTTCCAATCGGAAAGAATAAAGCAGAGAAAAATCTGATAAGAAAGGCAAGTGAAAATGTGAAAGGAATGGATTGGTTAAAGCCCAGATAGCGCTTGAGGAAGCCTCACAGCAACTGGTTGAAAAACAAAGGGAAAAAAATCAGGGGTTTGATTTTGATTCCTTTATTGCAGAAACTACTCAACCTAGTTCACAACATGAGCCTACTGATGTTGTTGAGAAATGAAATAACTCGAATAGGTCAAGGTCCCAACTAGAAATGAAAAATTTGATAACAAAGACAGTAAGCCAAGAAAAACAGAAAAAAGGAATGGCAAATTTGGCTCAGTTAGAAGTCTTGTACCAATCTTCTTGGGACAGCCAGTTTGTGAGTGGTGGGGAGAACTATTTTATCACAAATTAGTTTTGTTGTGAGGTAAGGAAGTGTGAAGGAGTTGAGGAGGACGACATTTACACTAGTTACTTAGACAAGTTATTTAACAGGAAAGAAGATACTGAAATACTAGAAACTGAGCTAGTAGAGGATGGGAAGCTTGGGGAGAGAGGAAATGAAGGATTTCTGAACAACAGTTTGGAGTTCCTCTTTAGCAAGCACCTCGAGTCCGTGGGCGTCCTGCAGCTTCGCAGTCCAGTTGGGTCACTACTTAAGTCAATACAGGCCACATTACCACCTTCTGCTATGGAATCTTCCCCTCAAATTCCTCATAAAACCTGCAGCAGCATTTTAAAACATGTGAACTAAAGCACTCAGCAAACATTTATCTTTGCATTCTTCATGAAATGTGTTTTGCCTTTATTTTATCACTAGTGTTTAAGTCATTTTTTACTTGAATCAGATGGTGTAATTTAGTAAGGATTAGCTCTTGGTTTTTAAAATCCAGACCTTATTTTCTACATATGAGGTAGTTTTCATTTTAACTGGCATGTCGTTTGCACACAAAAATAAGCAAAGAGCAAAATAATGCAATGCTAGAGGAGGCAAAAGAAATGCACTAAGACAAGTAAAAAACATCCTCTCGTAGAACAATGATCCGTTTTATAGGAAACAAATCTTACCTTGAAATTTACGCAGTGAGACTCTACATAATTGCCTGAAAATATCTATTTTTTCTAAAACATTTTTTATTCATGAATATTTTTTAAGTTTTTCACACTGTACACATTTCTTAAAACATATGATACCAGTAACAACTGAAAATGACTGCTGAATTGAGTACACATGTGTTATCTAGCTCAAGATAACAGAAGTATGTGGCAAAACATATACCACTCATAGTGCTTCACAATATGCACATCTATTTAGCCAGCATTTATTTTAGTAAACTATTCTTAATAAGACTCATTTACTGTTTATGAATATTCTGGTATGCATTCTTTATAGTGAAGTGTTAATATATCACATCTTATTTATTTTAGCAAATCAGTATATTTTCTGTATTTAATTATAAAAAGTAACTTAGTTTTTAAAATTTATTTGCAAATACACTTACTCCATCTGGCACTACAGCTTGTTGCCTACCTAACTGAATATATAATGTTAGCTCATCTTAAGCATGTCCATGTACTTAATTTACTTACGTGTTTATTTTAAGTAAACGATCACTGTATATAGGAATTTGTCTATGAAGAAATCACTGTATATAGGAATTTATCTATAAAGAAAAATTAGGAATTACTTTATTATAAATTACTCCTAGAAGTCTTGTGTTTATTTAAAAAGCTAATGTTAAAATTGTGTGTGTGGAAATAATTAAAGTCCATCATTATTGTAGTTTAAAAGTTGTATATGATACGACATTTTGATTTTACTGTATGTTTTTACTGAATGGTCTATTCCCCATCCCAAGGCAAACATGAATAAAATAAGATTAAATGTAGCATGTGGTATCACAGTCTCTTAGAATTTGTTTTGTCTATTTCATTGTATTGAATAGTCTGTATCTTTTGTTATCCTGTTTGAGGAAAAAGGACAAATAAAACATGGCCC

>NM_002748.4
CTTCCTCGCCCTCTCTCGCGGGTCGGGGTTACATGGCGGCGACTGCGGCAAAGCGAGAGCCTCGGAGACGCCGCTGCCGCCAGCACAGCCGGAGACCTGAGCCGACACTGGGGGCAGTCCGCGAGCCCCGCACTCTCTCGATGAGTCGGAGAAGTCCCGTTGTATCAGAGTAAGATGGACGGTAGCTTTGATTGTGATTGTGGTGAGCTGGAGCCACCTGATCACTAACAAAAGACATCTTCTGTTAACCAACAGCCGCCAGGGCTTCCTGTTGAAATAAATATATAGCAACAAAGGAAAAAAAGAAGCAAAACGGAAATAGTGCTTACCAGCACCTTAGAATGATGCTGCTCAGGACCAGTCCAACACTGAATGTATCTGCACTGTGAGGAGAATGTTCATAGAAGCCTGTTGTGTGCATATTTATTCACATTTTTGTTAAATGTTAAATCGTTTAGCACGGTAATCTGAGTGCACAGTATGTCATTTCATTCCGTTTGAGTTTCTTGTTTTCGTTAAATGTCTGCAGAGTTGCTGCCCCTTTCTTGAACTATGAGTACTGCAATCTTTTTAATTCTCAATATGAATAGAGCTTTTTGAGCTTTAAATCTAAGGGGAACTCGACAGGCCTGTTTGGCATATGCAATGAACATCAAGAAACCATCTTGCTGTGGAAGCATAATTATTTTTCTTCTCCCTTTTTGAAAGATCTTTCCTTTTGATGCCAGTTTTCTTCCTTGTTTACACAAGTTCAATTTGAAAGGAAAAGGCAATAGTAAGGGTTTCAAAATGGCAGAGAAATTTGAAAGTCTCATGAACATTCATGGTTTTGATCTGGGTTCTAGGTATATGGACTTAAAACCATTGGGTTGTGGAGGCAATGGCTTGGTTTTTTCTGCTGTAGACAATGACTGTGACAAAAGAGTAGCCATCAAGAAAATTGTCCTTACTGATCCCCAGAGTGTCAAACATGCTCTACGTGAAATCAAAATTATTAGAAGACTTGACCATGATAACATTGTGAAAGTGTTTGAGATTCTTGGTCCCAGTGGAAGCCAATTAACAGACGATGTGGGCTCTCTTACGGAACTGAACAGTGTTTACATTGTTCAGGAGTACATGGAGACAGACTTGGCTAATGTGCTGGAGCAGGGCCCTTTACTGGAAGAGCATGCCAGGCTTTTCATGTATCAGCTGCTACGGGGGCTCAAGTATATTCACTCTGCAAATGTACTGCACAGAGATCTCAAACCAGCTAATCTTTTCATTAATACGGAAGACTTGGTGCTGAAGATAGGTGACTTTGGTCTTGCACGGATCATGGATCCTCATTATTCCCATAAGGGTCATCTTTCTGAAGGATTGGTTACTAAATGGTACAGATCTCCACGTCTTTTACTTTCTCCTAATAATTATACTAAAGCCATTGACATGTGGGCTGCAGGCTGCATCTTTGCTGAAATGCTGACTGGTAAAACCCTTTTTGCAGGTGCACATGAACTTGAACAGATGCAGCTGATTTTAGAATCTATTCCTGTTGTACATGAGGAAGATCGTCAGGAGCTTCTCAGCGTAATTCCAGTTTACATTAGAAATGACATGACTGAGCCACACAAACCTTTAACTCAGCTGCTTCCAGGAATTAGTCGAGAAGCACTGGATTTCCTGGAACAAATTTTGACATTTAGCCCCATGGATCGGTTAACAGCAGAAGAAGCACTCTCCCATCCTTACATGAGCATATATTCTTTTCCAATGGATGAGCCAATTTCAAGCCATCCTTTTCATATTGAAGATGAAGTTGATGATATTTTGCTTATGGATGAAACTCACAGTCACATTTATAACTGGGAAAGGTATCATGATTGTCAGTTTTCAGAGCATGATTGGCCTGTACATAACAACTTTGATATTGATGAAGTTCAGCTTGATCCAAGAGCTCTGTCCGATGTCACTGATGAAGAAGAAGTACAAGTTGATCCCCGAAAATATTTGGATGGAGATCGGGAAAAGTATCTGGAGGATCCTGCTTTTGATACCAATTACTCTACTGAGCCTTGTTGGCAATACTCAGATCATCATGAAAACAAATATTGTGATCTGGAGTGTAGCCATACTTGTAACTACAAAACGAGGTCATCATCATATTTAGATAACTTAGTTTGGAGAGAGAGTGAAGTTAACCATTACTATGAACCCAAGCTTATTATAGATCTTTCCAATTGGAAAGAACAAAGCAAAGAAAAATCTGATAAGAAAGGCAAATCAAAATGTGAAAGGAATGGATTGGTTAAAGCCCAGATAGCGCTAGAGGAAGCATCACAGCAACTGGCTGGAAAAGAAAGGGAAAAGAATCAGGGATTTGATTTTGATTCCTTTATTGCAGGAACTATTCAGCTTAGTTCCCAGCATGAGCCTACTGATGTTGTTGATAAATTAAATGACTTGAATAGCTCAGTGTCCCAACTAGAATTGAAAAGTTTGATATCAAAGTCAGTAAGCCAAGAAAAACAGGAAAAAGGAATGGCAAATCTGGCTCAATTAGAAGCCTTGTACCAGTCTTCTTGGGACAGCCAGTTTGTGAGTGGTGGGGAGGACTGTTTTTTCATAAATCAGTTTTGTGAGGTAAGGAAGGATGAACAAGTTGAGAAGGAAAACACTTACACTAGTTACTTGGACAAGTTCTTTAGCAGGAAAGAAGATACTGAAATGCTAGAAACTGAGCCAGTAGAGGATGGGAAGCTTGGGGAGAGAGGACATGAGGAAGGATTTCTGAACAACAGTGGGGAGTTCCTCTTTAACAAGCAGCTCGAGTCCATAGGCATCCCACAGTTTCACAGTCCAGTTGGGTCACCACTTAAGTCAATACAGGCCACATTAACACCTTCTGCTATGAAATCTTCCCCTCAAATTCCTCATCAAACATACAGCAGCATTCTGAAACATCTGAACTAAAACACTCAGCAGACATTTATCTTTGTATTCTTCATGAAATGTGTTTTGTCTTTTTTTATTACTAGTGTTTAAGTCATTTTTTACTTGAATCAGATGGTGTCATTTAGTAAGGATTTTATGAGTTCTTGTTTTTTAAAATCCAGACTTTCTTTTTCTACATGTGAGATAGTTTTCATTTTAACTGGCATGTCATTTGCACACAAAAATAAAGACTAGAGCAAAATAATGCAACGCAGGAGGAGAAAAGAAATGCACTAAGACAAGAACATTCTCTCATAGAAcattgatctgttttacaggaaacaaaccttgccttgaaatttacacagtgagactgtacataattgcatgaaaatagctattTTTTTCCTAAGACATTTTTCATTCATGAATATTTTCAAGTTTTTCATACTGTACACATTTCTTAAAACACATGATACCAGCAGCAACTGAAAATGAATGCCGAATTTGGTACACATGTGTTATCTACCTCAAGGTAACAAGAGTATGTGGCAAAACATATACCACCCATAGTGCTTCACAAAATGCACTTCTATTTAGCCAGCGTTTATTGTAGTAAACTATTCTTAATAAAACTCACTCACTGTTTATAAATGTTCTGGTATGCATTCTTTATAGTGAAGTGTTAATACATCACATCTTATTTATTTTAGCAAATCAGTATATTTTCTGTATTTAATTATAAAAAATTAACTTAGTTTTTAAAATTTATTTGCAAATATACTTTACTTTTTCCATTTGGCACTATGGTTTGTTGCCTACCTAGCTGCATCTATAATGTCAGCTTATCCTAAGGCTGTCCACGTACTTAATTTACTTAAGTGTTCATTTTAAGTAACGTGCTCACTGTGTATAGGAATTTGTATTTTGGAGGTGCTTGATCTATCTACAAAGAAAAATTAATTAGGAATTACTTTATTATAAAATGCTCCTAGAAGTCTTAATTGTGTTTATTTTTTAAAAAAACAAATGTTAGACTTGTGTGCATGGAAGTAATTAAGGTACATCATTATTGTAGTTTGAAAGTTGTACATGATAAGACATTTTGTTTTTACTGTATGTTTTTACTGAATGATCTATTCCCCATCCCAAGGCAAGCATGAATAAAATTAGGTTAAACGTAGCATGTGGCATCGCAGTCTCTTAGAATTTGTTTCATCTATTTTATTTTATTGAATACTGTCTGTATCTTTGGTTATCCTGTTTGAAGAAAAAGGACAAATAAAACATGGCCAGCAAATACAGCTCCTGTTTCACTCTTGGGTTAATGAAAATTTTCTGCTAGAATGAAAATTACTACCAGAATCACTTTGAATTATGGCCATAAATTGCTAGTCTGAAAGGCTGAGAAGGTTCAAGTCTTTTGACTTAAACCATCACATATTAGAATGGAATAAAGCTTTATAATATTTCAAAACTGTTAGGTAAAATGTGTAGTTGAAACTTTGAACTGTGCAGTCAGAAAACTTGAGATTTGCTCTGTAATACATCTTTGCGTAAGAACTTACCCTTTTACCTATCCAGCTACAAAACCATCCTCTTCACCTCACTTTTCTTTCATCCTTGTTTTGTACAACACCAATTCTATTAATATCTGCCCACCTACCTTCTCAACAACTCCATCCTCTTCACCTCACTTTTCTTTCATCCTTGTTTTGTACAACACCAATTCTATTAATATCTGCCCACCTACCTTCTCAACAACTGACTTCATCTGGATTCACAAAGCCATATATATACACgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtATATATATTCATTTATTTATTTTCTGGTTGAATACTGTCACGTTATTAATTTAAACATACTCAAATTACCTTAAGAGGACAAGCTCTGAAGTGCAGTCATGAGAATTGATTTGTGGGGAAAAAAAAAATGGGACACTTTTAGTTGGAGCTGGGTGGGGTGACAAGTGCAGAGGCTTTGAGTGTCATGAGAGCATCAGACAGGATGTAAAGGAAGCAACGGGCAGCAGACATTGGTCCCTGATCCTCCATTATAACCAATTTTTTGCAAACGTATGTTGATTTTGAGAATAATTAGCTTTGACTCTAAAATGCTGTCTTCCCTGAAGGAGACCTAGGATTTTTCTTACTGGGAAACTTGGCTCCTGGACTTAATCCACATTCGTTAAACTGTCACCTTGGCAGTTTAGTGGCCATCTACACAATGATCTGACTTGTTGGCATTAAAAAGTCCAAACATAGTCATCAAAGGAAGAAGAAAGTAAAACTGAAACCCCTTATATAAAATATGCTTGCTTTAGGGTGACCCAGGCTGAGTACTAAGTTGTAAAGTCAATTTCCAATAAAAATTTTATGTGCCAATTA

>NM_002748.4 

CTTCCTCGCCCTCTCTCGCGGGTCGGGGTTACATGGCGGCGACTGCGGCAAAGCGAGAGCCTCGGAGACGCCGCTGCCGCCAGCACAGCCGGAGACCTGAGCCGACACTGGGGGCAGTCCGCGAGCCCCGCACTCTCTCGATGAGTCGGAGAAGTCCCGTTGTATCAGAGTAAGATGGACGGTAGCTTTGATTGTGATTGTGGTGAGCTGGAGCCACCTGATCACTAACAAAAGACATCTTCTGTTAACCAACAGCCGCCAGGGCTTCCTGTTGAAATAAATATATAGCAACAAAGGAAAAAAAGAAGCAAAACGGAAATAGTGCTTACCAGCACCTTAGAATGATGCTGCTCAGGACCAGTCCAACACTGAATGTATCTGCACTGTGAGGAGAATGTTCATAGAAGCCTGTTGTGTGCATATTTATTCACATTTTTGTTAAATGTTAAATCGTTTAGCACGGTAATCTGAGTGCACAGTATGTCATTTCATTCCGTTTGAGTTTCTTGTTTTCGTTAAATGTCTGCAGAGTTGCTGCCCCTTTCTTGAACTATGAGTACTGCAATCTTTTTAATTCTCAATATGAATAGAGCTTTTTGAGCTTTAAATCTAAGGGGAACTCGACAGGCCTGTTTGGCATATGCAATGAACATCAAGAAACCATCTTGCTGTGGAAGCATAATTATTTTTCTTCTCCCTTTTTGAAAGATCTTTCCTTTTGATGCCAGTTTTCTTCCTTGTTTACACAAGTTCAATTTGAAAGGAAAAGGCAATAGTAAGGGTTTCAAAATGGCAGAGAAATTTGAAAGTCTCATGAACATTCATGGTTTTGATCTGGGTTCTAGGTATATGGACTTAAAACCATTGGGTTGTGGAGGCAATGGCTTGGTTTTTTCTGCTGTAGACAATGACTGTGACAAAAGAGTAGCCATCAAGAAAATTGTCCTTACTGATCCCCAGAGTGTCAAACATGCTCTACGTGAAATCAAAATTATTAGAAGACTTGACCATGATAACATTGTGAAAGTGTTTGAGATTCTTGGTCCCAGTGGAAGCCAATTAACAGACGATGTGGGCTCTCTTACGGAACTGAACAGTGTTTACATTGTTCAGGAGTACATGGAGACAGACTTGGCTAATGTGCTGGAGCAGGGCCCTTTACTGGAAGAGCATGCCAGGCTTTTCATGTATCAGCTGCTACGGGGGCTCAAGTATATTCACTCTGCAAATGTACTGCACAGAGATCTCAAACCAGCTAATCTTTTCATTAATACGGAAGACTTGGTGCTGAAGATAGGTGACTTTGGTCTTGCACGGATCATGGATCCTCATTATTCCCATAAGGGTCATCTTTCTGAAGGATTGGTTACTAAATGGTACAGATCTCCACGTCTTTTACTTTCTCCTAATAATTATACTAAAGCCATTGACATGTGGGCTGCAGGCTGCATCTTTGCTGAAATGCTGACTGGTAAAACCCTTTTTGCAGGTGCACATGAACTTGAACAGATGCAGCTGATTTTAGAATCTATTCCTGTTGTACATGAGGAAGATCGTCAGGAGCTTCTCAGCGTAATTCCAGTTTACATTAGAAATGACATGACTGAGCCACACAAACCTTTAACTCAGCTGCTTCCAGGAATTAGTCGAGAAGCACTGGATTTCCTGGAACAAATTTTGACATTTAGCCCCATGGATCGGTTAACAGCAGAAGAAGCACTCTCCCATCCTTACATGAGCATATATTCTTTTCCAATGGATGAGCCAATTTCAAGCCATCCTTTTCATATTGAAGATGAAGTTGATGATATTTTGCTTATGGATGAAACTCACAGTCACATTTATAACTGGGAAAGGTATCATGATTGTCAGTTTTCAGAGCATGATTGGCCTGTACATAACAACTTTGATATTGATGAAGTTCAGCTTGATCCAAGAGCTCTGTCCGATGTCACTGATGAAGAAGAAGTACAAGTTGATCCCCGAAAATATTTGGATGGAGATCGGGAAAAGTATCTGGAGGATCCTGCTTTTGATACCAATTACTCTACTGAGCCTTGTTGGCAATACTCAGATCATCATGAAAACAAATATTGTGATCTGGAGTGTAGCCATACTTGTAACTACAAAACGAGGTCATCATCATATTTAGATAACTTAGTTTGGAGAGAGAGTGAAGTTAACCATTACTATGAACCCAAGCTTATTATAGATCTTTCCAATTGGAAAGAACAAAGCAAAGAAAAATCTGATAAGAAAGGCAAATCAAAATGTGAAAGGAATGGATTGGTTAAAGCCCAGATAGCGCTAGAGGAAGCATCACAGCAACTGGCTGGAAAAGAAAGGGAAAAGAATCAGGGATTTGATTTTGATTCCTTTATTGCAGGAACTATTCAGCTTAGTTCCCAGCATGAGCCTACTGATGTTGTTGATAAATTAAATGACTTGAATAGCTCAGTGTCCCAACTAGAATTGAAAAGTTTGATATCAAAGTCAGTAAGCCAAGAAAAACAGGAAAAAGGAATGGCAAATCTGGCTCAATTAGAAGCCTTGTACCAGTCTTCTTGGGACAGCCAGTTTGTGAGTGGTGGGGAGGACTGTTTTTTCATAAATCAGTTTTGTGAGGTAAGGAAGGATGAACAAGTTGAGAAGGAAAACACTTACACTAGTTACTTGGACAAGTTCTTTAGCAGGAAAGAAGATACTGAAATGCTAGAAACTGAGCCAGTAGAGGATGGGAAGCTTGGGGAGAGAGGACATGAGGAAGGATTTCTGAACAACAGTGGGGAGTTCCTCTTTAACAAGCAGCTCGAGTCCATAGGCATCCCACAGTTTCACAGTCCAGTTGGGTCACCACTTAAGTCAATACAGGCCACATTAACACCTTCTGCTATGAAATCTTCCCCTCAAATTCCTCATCAAACATACAGCAGCATTCTGAAACATCTGAACTAAAACACTCAGCAGACATTTATCTTTGTATTCTTCATGAAATGTGTTTTGTCTTTTTTTATTACTAGTGTTTAAGTCATTTTTTACTTGAATCAGATGGTGTCATTTAGTAAGGATTTTATGAGTTCTTGTTTTTTAAAATCCAGACTTTCTTTTTCTACATGTGAGATAGTTTTCATTTTAACTGGCATGTCATTTGCACACAAAAATAAAGACTAGAGCAAAATAATGCAACGCAGGAGGAGAAAAGAAATGCACTAAGACAAGAACATTCTCTCATAGAAcattgatctgttttacaggaaacaaaccttgccttgaaatttacacagtgagactgtacataattgcatgaaaatagctattTTTTTCCTAAGACATTTTTCATTCATGAATATTTTCAAGTTTTTCATACTGTACACATTTCTTAAAACACATGATACCAGCAGCAACTGAAAATGAATGCCGAATTTGGTACACATGTGTTATCTACCTCAAGGTAACAAGAGTATGTGGCAAAACATATACCACCCATAGTGCTTCACAAAATGCACTTCTATTTAGCCAGCGTTTATTGTAGTAAACTATTCTTAATAAAACTCACTCACTGTTTATAAATGTTCTGGTATGCATTCTTTATAGTGAAGTGTTAATACATCACATCTTATTTATTTTAGCAAATCAGTATATTTTCTGTATTTAATTATAAAAAATTAACTTAGTTTTTAAAATTTATTTGCAAATATACTTTACTTTTTCCATTTGGCACTATGGTTTGTTGCCTACCTAGCTGCATCTATAATGTCAGCTTATCCTAAGGCTGTCCACGTACTTAATTTACTTAAGTGTTCATTTTAAGTAACGTGCTCACTGTGTATAGGAATTTGTATTTTGGAGGTGCTTGATCTATCTACAAAGAAAAATTAATTAGGAATTACTTTATTATAAAATGCTCCTAGAAGTCTTAATTGTGTTTATTTTTTAAAAAAACAAATGTTAGACTTGTGTGCATGGAAGTAATTAAGGTACATCATTATTGTAGTTTGAAAGTTGTACATGATAAGACATTTTGTTTTTACTGTATGTTTTTACTGAATGATCTATTCCCCATCCCAAGGCAAGCATGAATAAAATTAGGTTAAACGTAGCATGTGGCATCGCAGTCTCTTAGAATTTGTTTCATCTATTTTATTTTATTGAATACTGTCTGTATCTTTGGTTATCCTGTTTGAAGAAAAAGGACAAATAAAACATGGCCAGCAAATACAGCTCCTGTTTCACTCTTGGGTTAATGAAAATTTTCTGCTAGAATGAAAATTACTACCAGAATCACTTTGAATTATGGCCATAAATTGCTAGTCTGAAAGGCTGAGAAGGTTCAAGTCTTTTGACTTAAACCATCACATATTAGAATGGAATAAAGCTTTATAATATTTCAAAACTGTTAGGTAAAATGTGTAGTTGAAACTTTGAACTGTGCAGTCAGAAAACTTGAGATTTGCTCTGTAATACATCTTTGCGTAAGAACTTACCCTTTTACCTATCCAGCTACAAAACCATCCTCTTCACCTCACTTTTCTTTCATCCTTGTTTTGTACAACACCAATTCTATTAATATCTGCCCACCTACCTTCTCAACAACTCCATCCTCTTCACCTCACTTTTCTTTCATCCTTGTTTTGTACAACACCAATTCTATTAATATCTGCCCACCTACCTTCTCAACAACTGACTTCATCTGGATTCACAAAGCCATATATATACACgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtATATATATTCATTTATTTATTTTCTGGTTGAATACTGTCACGTTATTAATTTAAACATACTCAAATTACCTTAAGAGGACAAGCTCTGAAGTGCAGTCATGAGAATTGATTTGTGGGGAAAAAAAAAATGGGACACTTTTAGTTGGAGCTGGGTGGGGTGACAAGTGCAGAGGCTTTGAGTGTCATGAGAGCATCAGACAGGATGTAAAGGAAGCAACGGGCAGCAGACATTGGTCCCTGATCCTCCATTATAACCAATTTTTTGCAAACGTATGTTGATTTTGAGAATAATTAGCTTTGACTCTAAAATGCTGTCTTCCCTGAAGGAGACCTAGGATTTTTCTTACTGGGAAACTTGGCTCCTGGACTTAATCCACATTCGTTAAACTGTCACCTTGGCAGTTTAGTGGCCATCTACACAATGATCTGACTTGTTGGCATTAAAAAGTCCAAACATAGTCATCAAAGGAAGAAGAAAGTAAAACTGAAACCCCTTATATAAAATATGCTTGCTTTAGGGTGACCCAGGCTGAGTACTAAGTTGTAAAGTCAATTTCCAATAAAAATTTTATGTGCCAATTA

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