Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name SRMP3
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:128139484-128140491  UCSC
Coordinates (T2T) chr2:128575451-128576458  UCSC
Coordinates (hg19) chr2:128897058-128898065  UCSC
Strand -
Parental Sequence NM_003132.3
Parental seq. overlap 784 bp
Parental seq. overlap (%) 61.1%
Genomic Region Intragenic (UGGT1)
Retrocopy Summary SRMP3, located on chr2:128139484-128140491, is a retrocopy of the parental gene SRM. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SRM
Full Name spermidine synthase
Also known as PAPT|SPDSY|SPS1|SRML1
Coordinate chr1:11054589-11060053
Strand -
Gene summary The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SRMP1
Bonobo Pan paniscus SRMP1
Gorilla Gorilla gorilla SRMP1
Orangutan Pongo abelii SRMP1
Gibbon Nomascus leucogenys SRMP5
Green monkey Chlorocebus sabaeus SRMP2
Crab-eating macaque Macaca fascicularis SRMP3
Rhesus Macaca mulatta SRMP3
Baboon Papio anubis SRMP3
Golden snub-nosed monkey Rhinopithecus roxellana SRMP7
Marmoset Callithrix jacchus SRMP3
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SRMP3
GACATTCGGCCTCCAAGCCTATACCAGCTGTGTACAGTACCATCTCTCTATGGAGCAGCTGCTCCACTGCCAGCGCTCACGCTCCCAGGATATCCTTGTTTTCCACAGTAAGACCCACAGCAGTGTGCTGGTGTTGGATGGCATCATCCCCTGCATGGACAGGGACAAGTTCTCCTACTAGATGAGAATCAACCTGCCATTCAGCAACCACCCCATCCCACAAAAGGTGCTGATCGTCGGGGACAAAGACGGCATCCTGCACAAGGTGGTGAAGCACCCCTCTGTGGAGTCTGTGGTCCGATGATAGACTGAAAAGGATGGCACTCAGGTCTCTAAGAAATTCCTGCCGGGTATGGCCATTGGCTTCTCTAGCTCTAAGCTGACCCTGCATATGGGTGACGATTTTGATTTCGTGAAGCAGAACCAGGATGCCTTCAATATTATGATCACTGACTCCTGGGATCCGCTGAGAGCCTCTTCAAGGAATCCTATTACCACTCATGAAGATGGCCCTCAACGAGGACAGCATTCTCTGCTGCCAGGGCGAGTACCAGTGGCTGCACCTGGACCTCATCAAGCAGACACGGTAGTTCTGCCAGTCACTCTTCTCCATGGTGGCACACGCCTACTGCACTGTCCCCACCTATCCCAGTGGCCAGATTGCCTTCATGCTCTGCAGCAAAAACCCGAGCACCAACTTCCAGAAGCCCATGCAACAAGTGACACGGCAGCAGGTGGAGCAGGTGCAGCTGCTCAGATGTGTACAGTGCTGCCTTCGTACTGCCCAAGTTTGCCTGCAAGTCCCTGAATGATGTGAGCTGAACCCAGGCGCCACAGCAGGTGCCACCCGGGATCTCAGATCTGGGAGCCTCCAGGATGCCTGCGCCCCTTCAGCCCTAGGCCAGATCCCCTGCTGACTGTCACCTGCCAACCAAGTGTTACAAGCCTCAGAATACTGCCCAGCTTTCCCTGc
>NM_003132.3
GCTGGTCCCGTTGTGCTGCGGCGCCGCGCGGCCTGCAGTCCCGGGCCCGCGCCCCGCGCCGCCCGCCCGCCCGCCATGGAGCCCGGCCCCGACGGCCCCGCCGCCTCCGGCCCCGCCGCCATCCGCGAGGGCTGGTTCCGCGAGACCTGCAGCCTGTGGCCCGGCCAGGCCCTGTCACTGCAGGTGGAGCAGCTGCTCCACCACCGGCGCTCGCGCTACCAGGACATCCTCGTCTTCCGCAGTAAGACCTATGGCAACGTGCTGGTGTTGGACGGTGTCATCCAGTGCACGGAGAGAGACGAGTTCTCCTACCAGGAGATGATCGCCAACCTGCCTCTCTGCAGCCACCCCAACCCGCGAAAGGTGCTGATCATCGGGGGCGGAGATGGAGGTGTCCTGCGGGAGGTGGTGAAGCACCCCTCCGTGGAGTCCGTGGTCCAGTGTGAGATCGACGAGGATGTCATCCAAGTCTCCAAGAAGTTCCTGCCAGGCATGGCCATTGGCTACTCTAGCTCGAAGCTGACCCTACATGTGGGTGACGGTTTTGAGTTCATGAAACAGAATCAGGATGCCTTCGACGTGATCATCACTGACTCCTCAGACCCCATGGGCCCCGCCGAAAGTCTCTTCAAGGAGTCCTATTACCAGCTCATGAAGACAGCCCTCAAGGAAGATGGTGTCCTCTGCTGCCAGGGCGAGTGCCAGTGGCTGCACCTGGACCTCATCAAGGAGATGCGGCAGTTCTGCCAGTCCCTGTTCCCCGTGGTGGCCTATGCCTACTGCACCATCCCCACCTACCCCAGCGGCCAGATCGGCTTCATGCTGTGCAGCAAGAACCCGAGCACGAACTTCCAGGAGCCGGTGCAGCCGCTGACACAGCAGCAGGTGGCGCAGATGCAGCTGAAGTACTACAACTCCGACGTGCACCGCGCCGCCTTTGTGCTGCCCGAGTTTGCCCGCAAGGCCCTGAATGATGTGAGCTGAGCCCAGGCGCCACCACTGATGCCACCCAGGACCTCGGACCTTGGAGCCTGCGGGGTGCCTCGGCCCCTCCAGCCCCGGGCCGGACCTCCTGCTGGCTCTCGCCCACCAACCAAGTGTTACAAGCCCCAGAATGCTGCCCGGCCTGCCCTGCTGGGCGGActgtctgtgtgtctgtctctctgGCGTTCCACCTCCAAGCCTATACCAGCTGTGTACAGCGCCATCTCTCTGCCTTCTGTTGCCCCTCACTCACCAAACACGTGTATTTATAGCAAA

Publications

PMID - Link Title