Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RHOQP3
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:130210867-130213809  UCSC
Coordinates (T2T) chr2:130644763-130647706  UCSC
Coordinates (hg19) chr2:130968440-130971382  UCSC
Strand -
Parental Sequence NM_012249.4
Parental seq. overlap 2865 bp
Parental seq. overlap (%) 59.8%
Genomic Region Intergenic
Retrocopy Summary RHOQP3, located on chr2:130210867-130213809, is a retrocopy of the parental gene RHOQ. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RHOQ
Full Name ras homolog family member Q
Also known as ARHQ|HEL-S-42|RASL7A|TC10|TC10A
Coordinate chr2:46542409-46584688
Strand +
Gene summary This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus RHOQP1
Gorilla Gorilla gorilla RHOQP1
Orangutan Pongo abelii RHOQP1
Chimpanzee Pan troglodytes Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RHOQP3
CTTATGATCCGGCGGATCCTCTCCTGGGGAGACCAGGCCGGGGAGAGGGCGCGGGCGCCCAGTGGCGGGGGCAGCGGGCAGGCGCAGCGACCGGGGCCGGGGCGGGGATCCTGGCGGCGACCGCCGCGGCGGCAGCGCCCCGGGCCCGCCGCCCCCTCCCCTCCGGCGAGGGGAGCCGCTGGATGGGGCCGGTCGGGGGGCGGCCTGCGGCGCAGAGCGGCGGCGACGGCGGCGGACTCCCCAGGCGGGCTGGGGCTGAGCCCGGGGACCGGGGCGGGGGCTCCGGGGGGACCATGCCCGGAGGCCGGCGGGCAGCAGCGTGGCTCACGGGCCTGGCGCGCTGATGCTCAAGTGCGTGGTGGTCGGCGACGGGGCGGTGGGCAAGACGTGCCCACTCATGAGCTATGCCAACGAAGCCTTCCCGGAGGAGTACGTGCCCACCGTCTTCGACCACTAAGCAGTCAGCGTCACTGTGGGGGGCAAGTAGTACCTCCTAGGACTCTATGACACGGCCGGACAGGAAGACTATGACTGTCTGAGGCCTTTATCTTACCCAGTGACCGACGTCTTCCTTATATGCTTCTCGGTGGTAAATCCAGCCTCATTTCAAAATGTGAAAGAGGAGTGGGTACCGGAACTTAAGGAATACGCACCAAATGTACCCTTTTTATTAATAAGAACTCAGATTGATCTCCGAGATGACCCCAAAACTTTAGCAAGACTGAATGATATGAAAGAAAAACCTATATGTGTGGAACAAGGACAGAAACTAGCAAAAGAGATAGGAGCATGCTGCTATGTGGAATGTTCAGCTTTAACCCAGAAGGGATTGAAGACTGTTTTTGATGAGGCTATCATAGCCATTTTAACTCCAAAGAAACACACTGTAAAAAAAAAAAGAATAGGATCAAGATGTATAAACTGTTGTTTAATTACGTGAGAAACATCTTCAGTGGCCAAGGAAACTGGCCATTTCTCTGAGAAAGCAAATGAAATGCTACAGCTATACCCAGACCTTTTATAGGTAATGAAGCAGTTCAAAACTTGAAAGAAAACAAAACCTGTCCCCAGAATTCCATAAAGTTTATTAAGAATGTTCCTTAAAGGTTTAAGAAGCAGTAAGCAGTATCTGAAGCCACAATCTACTATAAATACTTTATTTCAACTAGAAGGTACAATCTCTCAGGGGTTTCATAGTTTAAAAAGCTACAATCACATCATGTAACTACGTAAAAAACAGAGCTGTAAATGGAACTGCTTGGCTTTGACCATACACATTTCTGCACAGCCCTTACAGAATCTGCACAAAGAAATATCTCCCTTTGTTCCAGTTAATTGTTCTTGTATGTAAGTTGCTTTCTATTCCAGTATATCCAGAGTGGTGAAATAACAAGGCCAGCCACATAGCCAAAGGTCGCTCCAAGCGTACAGGAGATGGGCCATACCTGAGGAGAGAATGTATGAGATCAAAAAAGAACAAATGTTTTATTATTACTTGAGCACAAGTGTAACCTAAATATTTCTATATTAAAGCTTAATGTGCTTTCTTAAAGAATGCCTAAAGTGTAATAAGGTCATAACTGCATTTATCATGAACACTAAAAATGTACACATTTTAGTTAATGTGCATTAAACTGTAACAAGGCTTCGGGCAATTGTAGATTTAGTTTGACGCTCCCCAAAGTGCATGAGACACATGCTAAAATTACAAATTAAAATTTTGGGTCAGACTTTGCCATAATGCTGGACTCAATTTAGCTCTCTGAACTAGATGGTAATTTTTTTTTAATTCCCACTTTGGCTGTGTACATCAAATGAAATGAGAAGTGTGTATGCTGACCAAACCACAAGAAACTTTAAGTTGTGTTAAAGAGGAAAGACCTAGAATCCAAGCATGTTACATGAAAATTGTAACAGAGCAGCTGCTTCCACCTTTCAGATATAGATGTTGGGACCACAGCAGAAGTTATAGAGCGAGAACTTATATACACACCTAGAATGTAAGTTAAACAAAATACCGGCTTCCGGAGACCCATTTTCTCCAGCCATATTACATTAGGCTAGAAGTAATTAATGTTGATTTATTTCATCTACAAGCAGTTGGTCCCTAAGTGACAGGCTCTGCTTCAAAAAAAAAAGTTGGAGAAAAATTTTCATGTTCTTCTGTGAAGCTTATTTGGTACACTGGAGCCTTTTCTAATCTTTCTCTCGGGGGAACAGGCTGCAGAACTGTGTTAGAGGTGAACCATCTTAATTACTAGTTCTATTACCTAATTCAGCTTCCTTGTTTGGTCTGCTGTGGATCTGCCTTATTGCATATGCCATGCATCAGATAATGGTGTTAGACAAAGCTTCATTGTGAACAACCTAATGCATTTTAGAGAAACAATCTCATCTACACATTTTTTTCTAGCCTTTCCTACATTTAAACTTGCTGTTGCCTAAATTATAATTTTTTAAATGTCTTTGGTGGGCTTCTGTTAATTCATGTGACTTGAGCTTATAGCTATGTCTACTGCACAGATTGGGTAATGGAACACTAAACTTTTATACTTGAAAATGACAGCCTTAAATGCTCATATCAGTCACAAATCTAGGATGTACTGTCTTGTTGTATGTGAGCTTTGTAGAGATTTGTAAAAATATAAGCATCACCTTCGCACTGAAGAGTGGAGAGAGTCTACTGGATGACTGGCCAGGAACTTTCTCTCTGAATTGGACATTTGGATGTCTTCTTTCTTCCAAGAAATGGTGGTTCACATTAAAGTATCATGGCCTTATGTATGCTCAAATGGAATCTTATGTAAGTTTCTTAATTTAATTTTGGTCTGCTATTTTTAGATAAAATTGAAAGGAATTGTATAAATCAATTAACATATTAGCTAAGTTGTCCAACACATGTTATAAATGAATTACAACAGTAAACTATTATACATTTCCAAA
>NM_012249.4
ctcctcctgcgcgcccctccGCGCGGCCCTCGCAGGGAGTGGGGCTCGGGTGCGCCGGCAGGGCCGCGCGGCGGCAGCAGGCGGGGGCGCGTGGCGCGGGCCGCGCTCGGGGAGGCGCCTGGGCCCGCCCTCCTCCGGGGCGCCGCGGGAGGGGCCCGGGTTGGCGCGGGGCGGGGAGAGCCGCCTGGCCCCTCCCCTCCGCCGCCCTCCCCAAAGTTGCCGTCTCCCCCGGGGCCGGCCGGTCTTATGATCCGGCGGATCCTCCTGGGGAGGCCGGGCCGGGGAGAGGGCGCGGGCGCCGAGTGGCGGGGGCAGCGGGCGGGCGCGGCGACCGGGGCCGGGGCGGGGATCCGGGCGGCGACCGCGGCGGCGGCAGCGCCCCGGGCCCGCCGCCCCCTCCCCTCCTGCGAGGGGAGCCGCTGCATGGGGCCGGGGGGGCGGCCCTGCGGCGCGGAGCGGCGGCGACGGCGGCGGACCCCCCAGGCGGGCTGGGGCTGAGCCCGGGGCCGGGGCGGGGGCTCCGGGGGGACCATGCCCGGAGGCCGGCCGGCAGCAGCATGGCTCACGGGCCCGGCGCGCTGATGCTCAAGTGCGTGGTGGTCGGCGACGGGGCGGTGGGCAAGACGTGCCTACTCATGAGCTATGCCAACGACGCCTTCCCGGAGGAGTACGTGCCCACCGTCTTCGACCACTACGCAGTCAGCGTCACCGTGGGGGGCAAGCAGTACCTCCTAGGACTCTATGACACGGCCGGACAGGAAGACTATGACCGTCTGAGGCCTTTATCTTACCCAATGACCGATGTCTTCCTTATATGCTTCTCGGTGGTAAATCCAGCCTCATTTCAAAATGTGAAAGAGGAGTGGGTACCGGAACTTAAGGAATACGCACCAAATGTACCCTTTTTATTAATAGGAACTCAGATTGATCTCCGAGATGACCCCAAAACTTTAGCAAGACTGAATGATATGAAAGAAAAACCTATATGTGTGGAACAAGGACAGAAACTAGCAAAAGAGATAGGAGCATGCTGCTATGTGGAATGTTCAGCTTTAACCCAGAAGGGATTGAAGACTGTTTTTGATGAGGCTATCATAGCCATTTTAACTCCAAAGAAACACACTGTAAAAAAAAGAATAGGATCAAGATGTATAAACTGTTGTTTAATTACGTGAGAAACATCTTCAGTGGCCAAGGAAACTGTCCATTTCTCTCAGAAAGCAAATGAAATGCTACAGCTATACCCAGACCTTTTATAGGTAATGAAGCAGTTCAAAACTTGAAAGAAAACAAAACCTGTCCTCAGAATTCTATAAAGTGTATTAAGAATGTTCCTTAAAGGTTTAAGAAGCAGTAAGCAGCATCTGAAGCCACAATCTATTATAAATACTTTATTTCAACTAGAAGGTACAATCTCTCAGGGGTTTCATAGTTTAAAAAGCTACAATCACATCATGTTGTAACTACGTAAAAAACAGAGCTGTAAATGGAACTGCTTGGCTTTGACCATACACATTTCTGCCCAGCCCTTACAGAATCTGCACAAAGAAATATCTCCCTTTGCTCCAGTTAATTGTTCTTGTATGTAAGTTGCTTTCTATTCCAGTATATCCAGAGTGGTGAAATAACAAGGCCAGCCACGTAGCCAAAGGTCGCTCCAAGCGTACAGGAGATGGGCCATACCTGAGGAGAGAATGTATGAGATCAAAAAAGAACAAATGTTTTATTATTACTTGAGCACAAGTGTAACCTAAATATTTCTATATTAAAGCTTAATGTGCTTTCTTAAAGAATGCCAAAAGTGTAATAAGGTCATAACTGCATTTATCATGAACACTAAAAATGTACACATTTTAGTTAATGTGCATTAAACTGTAACAAGGCTTCTGGCAATTGTAGATTTAGTTTGACGCTCCCCAAAGTGCATGAGACACATGCTAAAATTACAAATTAAAATTTTGGGTCAGACTTTGCCATAATGATAGACTCAATTTAGCTCTCTGAACTAGTTGGTAATTTTTTTTTTTTAATTCCCACTTTGGCTGTGTACATCAAATGAAATGAGAAGTGTGTATGCTGACCAAACCACAAGAAACTTTCTTTAAGTTGTGTTAAAGAGGAAAGACCTAGAATCCAAGCGTGTTACATGAAAATTGTAACAGAGCAGCTGCTTCCACCTTTCAGATATAGATGTTGGAACCACAGCAGAAGTTATAGAGCGACAACTTATATACACACCTAGAATGTAAGTTAAACAAAATACCGGCTTCCAGAGACCCCTTTTCTCCAGCCATATTACATCAGGCTAGAAGTAATTAATGTTGATTTATTTCATCTACAAGCAGTTGGTCCCTAAGTGAAAGGCTCTGCTTGaaaaaaaaaagaaaaaaaaGTTGGAGGAAAATTTTCATGTTCTTCTGTGAAGCTTATTTGGTACACTGGAGCCATTTCTAATCTTTCTCTGGGGGGAACAGGCCACAGAACTGTGTTAGAGGTGAACCATCTTAATTACTAGTTCTATTACCTAATTCAGCTTCCTTGTTTGGTCTGCTGTGGATCTGCCTTATTGCATATGCCATGCATCAGATAATGGATGCATCAGATAATGGTGTTAGACAAAGCTTCATTGTGAACAACCTAATGCATTTTAGAGAAACAATCTCATCACATTTTTTCTAGCCTTTCCTACATTTAAACTTGCTGTTGCCCAAATTATAATTTTTTAAATGTCTTTGGTGGGCTTCTGTTAATTCACATGACTTGAGCTTATAGCTATGTCTACTGCACAGATTGGGTAATGGAACACTAAACTTTTATACTTGAAAATGACAGCCTTAAATGCTCATATCAGTCACAAATCTAGGATGTACTGTCTTGTTGTATGTGAGCTTTGTAGAGATTTTTAAAAATATAAGCATCACCTTCCCATTGAAGAGTGGAGAGAGTCTACTGGATGACTGGCCAGGAACTTTCTCTCTGAATCGGACATTTGGATGTCTTCTTTCTTCCAAGAAATGGTGGTTCACATTAAAGTATCATGGCCTTATGTATGCTCAAATGGAATCTTATGTAACTTTCTTATTTAATTTTGGTCTGCTTATTTTTAGATAAAATTGAAAGGAATTGTATAAATCAATTAACATATTAGCTGAGTTGTCCAACACATGGTATAAACGAATTACAACAGTAAACTATTACACATTTCCAACTTGCCTTTGGGGATTTATGAGGATTTTTTTTGGTGGGGGGAGGGGGCTCCAATTCATATCTCTGAAACCCTTCACACTTGGTTTACTAATTCAAAGTTAGAAGTCTAGAATTTGCCCTGCCCTAACAGAAACAGATTAGGAATTTGTCTACACAAACTGGTGTCACCTGTTTCTTGActgggatttggtttcctcattataaatatgggaggtagaacagagatctccaacgtctctcccatttatcacagtaattttcttattcACAGTAATCATTGTTGGATGTTACCTTTTCAGCTTCACATTCTCAAGATGGTAAAAATCATGTATATAGATTATCAGAACTCTAAGCAAAGATGACTGTCACATCTGAAGCTGAGGTGCCTTAGGTACTCTACTGACCTTGATGGGTTTGGAGTTCCCCATTGCTTATCAAGAGCTTTTTAATTGCTTTGGTTCTTTAGTTTTTCTTTTTGCAAAAATCCTTCCTGTCACTTTAACTAAAAACCAAAGATTTGTTTTCTATTGATAAGCAGACTAGAGAAAAACTGCCTTATTTTCAGAAGCATGTCTTCATTCAAAGCTTAGGCTTCAATAGAAATTCAGACTAATCACTGAAATGACTATTTCAAACTAGTGAAATATCTGGGAAATAAACTGCTTCAAAAATATTTTACTGACATGAATTTTGCTAGTGAATACAAATACACTGCCTCAAATAAGGCCATGTATGAATGAACTTACAAGATATTTGAGTTAATCAGTGTTTGCATATAGAGAATTAGTTCTAAAGTTCTTAAAAATAAATTTAGGGGCTCCCTGAAATTTTATTTAATACTTTGCTAACTTACACTCTTGTTTTATCTCCACAGGTACATTTTAGGTTAGCTCATGGTGAATTCTATTTACAATAAGTGGAGCTTGGATTAATGGGTTTTGTTATGAATTATCTTAGTGACTTTAGACACTGTTTCCATTTGATTTTTAACTATTTAAAATACCAAATTAAATACCAGTTTGTTGGTTGTTACTTTTAAATGATTGTTACTTTAACAGTGTCCCTTCTTAACACATGGGGTTACAAATAAAATACTATGCATAGTTTACTATCTACGTAAAGCACTGAACTTTTTACCTTAGTAGTTTTTATTTATTACCCTATGTAAACATTTAGGATAATACTCTTTCCTCTATTTATGCTGAGAGTCTACTAATCATTGGCAAAGTATGAGTCCCTATACTCTGTTAAAAAAAGCTCACTGTTAaagtatagggagaatagtaatccctcatgaatcccagctagattccaatttgggttactaaattgtattttaatcattttgtaatttcagtatggctctttgttctcaaacacatacataccaccacgcacattcttttaaacagctgccacacctcacctcCAACAGAATGCCAAAAATGAAATGTTAAAAAATTTTGTCTAATGAAGGGTTACGGCTTGGAACACTTGGTTATTCATGTTATGTAAATCAAGAAGTGCATGCCATCAGCAAATTAAAATGTGGACTGGCTTTGAAGACTGTTAA

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