Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MANEALP1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:135897097-135898634  UCSC
Coordinates (T2T) chr2:136341522-136343059  UCSC
Coordinates (hg19) chr2:136654667-136656204  UCSC
Strand -
Parental Sequence NM_001113482.2
Parental seq. overlap 911 bp
Parental seq. overlap (%) 33.6%
Genomic Region Intergenic
Retrocopy Summary MANEALP1, located on chr2:135897097-135898634, is a retrocopy of the parental gene MANEAL. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MANEAL
Full Name mannosidase endo-alpha like
Also known as -
Coordinate chr1:37793816-37801133
Strand +
Gene summary Predicted to enable alpha-mannosidase activity. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MANEALP1
Bonobo Pan paniscus MANEALP1
Gorilla Gorilla gorilla MANEALP1
Orangutan Pongo abelii MANEALP1
Gibbon Nomascus leucogenys MANEALP1
Green monkey Chlorocebus sabaeus MANEALP1
Crab-eating macaque Macaca fascicularis MANEALP1
Rhesus Macaca mulatta MANEALP1
Baboon Papio anubis MANEALP1
Golden snub-nosed monkey Rhinopithecus roxellana MANEALP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MANEALP1
CCAAACCCAAGCCTCTGTGCTCCAGAGCCTACTTTTTCCCAGGTGCATATTTAGCTCCAGGGAGAGGACTAGGAGGACACCCCCCCTCCCTTTAGCTGCCTGAACTGAATGAGGCCCACTCACTAAAGCCACGTCCAGTGCTCCTGTGATTTGTGGTAATTAAATATGAACCGGTAAGACCCAAGCTTTCCTTATCCGGTGCAGCCTTGTAGCTAGTGCCTGGGCACAGGTGTTTTTCTTTTTGCAGTTTTGCCTGGTGCTAGGAGTTCAGTTCTTTTTGCTCCAAAAAACACCTCTAAGTAGGTCAGGATGACATCACTGTACATGACAACATCAAGTATATCATTGACGTGAATGGCTCCCATGGTGCATTTTATCCCTGTATAAGAACAGCATGGGCAAGAGCACCCCACTCTTTTATATCTATGACTCATACCTGACATCCCTTGAGGCCTGGACCCACCTCCTGACACCAAACAGCCCCCACTATGGGGTCTTCATAGCACTATTGGTGGAAGAGGGCCACACCTACGATGTCCTGGCCGCAGGGTTTGAAGGCATGTCCACCTACTTTGTCTCCAATGGATTCTCCTGGGGCTCCTCCCATCAGAAGTGGAAAGCTGTGAAGAACTTTTATGATGCCAACAACCTCATGTTCATTCCCAGCATGGGGCCTGGCTGCATAGACACTAGCATCCGGCCCTGGAACGACCACAATAGGGAGAAGAGGGTCAATGGCAAGGACTATGACAGGGCCTTGCAGGCGGCCGCGATGGTGACGCCCAAGATCAGCTCCATCACCTCCTTCAATGAGTGGCCCGAGGGCACCCAGATGGAGAAGACCACTCCCAAGAAGACACCCCCGCCTGTATTTGGACTACCTGCCTCCTCAGCACAGCCTGTACTTGGAGCTGACCCGCTGCTGGGCGAGCACTTCATCAAAGAGAAGGTGCAGTGGCTCAGGTGAGGGGCCTGTAAACAGGGGTGTGACGTGCTAATGCCCTTGTCTCTCCGGAAGAAGTCACCACATGGGGCTCAGCTGAGGTTGGAGGCACTCACTCCTTCCCATGTTGGCAGCTGAGTGCTTCTGGGTGGGCCCTCAGATAACCCAATTATCTGGAAATCATCCTGAGCACTCTCAGG
>NM_001113482.2
AGGCGCCACCACCTGCCGCCCAGGCAGCCAGGCGACTCTTCTTTCGCGGGTCACGCGGCCTGACTCAGGCCCCTGCTCCTGTGGCCCCGAAACTCGCCGTTCGCTGGGCCTTGCGTTGCACTCGGCGTGCAGTTCCCCCTCGGCTCGCGGCCACTTGGTCCGCGCCGCCTGCGTCCTGTGTGCCGAGCCCGCCCGCACTGCGGGGACAGGCCGGGCGCCGCCCACGCCGCGCTCTGCCGGGCGCACAGTCTGCCTGGGAAGCGCGCGGCCGGGCGGGCGGCCATGGCGCGGCACGCTGGGAGGTAGCGCGGCGGCTGCAGGAGCGCACAGTCGGCCATGGCCCGGCGGCGGCGCCGCGCCTGCATCGCTCTGTTCCTGGTGCTGCTCTTCGCCTTCGGCACCCTCATGGGTCTGCGCACGCTCAAGGCTCCGGACGGACTCCCGGCGCTGGGCCCGGGCCTGGAGCTGGCGCCCTTTGAGCGACGCCCAGAGGGGGCCCCCGCGCCCGCTGCCAGGGCCCCGGCAGCCCCTGCCGCGCCGCCCCCGCCGCCGCCGCCGCCCCGCACCGCGGACCCTGGCGGCTCCCCTGGGCCGGCACCCGCGGAGGCCGAGCCCGCCCCCGTGCAGAGCCTGCGCGTCTACTCGGACCTGCACGCCTTCTACTACTCGTGGTACGGGAGCCCGCGGCGCGAGGGCCACTACATTCACTGGGACCACGTCATGGTGCCGCACTGGGACCCCAAGATCTCGGCCAGCTACCCCCGCGGCCGCCACAGCCCCCCAGACGACTTGGGCTCCAGCTTCTACCCGGAGCTGGGGCCCTACAGCTCCCGGGACCCCGAAGTGCTGCGGGAGCATATGACCCAGCTCAAGGAAGCCGCCATCGGCGTCCTGGTCCTGTCCTGGTACCCACCTGGCATGGCTGATGATAACGGGGAGCCCTCAGATGACCTGGTGCCCGCCATTCTGGACACCGCCCATCAGTACAGCATCCAGGTGGCCTTCCACATCCAACCCTACAAGGGCCGGGATGACATCACTGTACATGACAACATCAAGTACATCATTGACACGTATGGCTCCCATGGTGCATTTTACCGCTATAAGAACAGCATGGGCAAGAGCCTCCCACTCTTTTATATCTACGACTCATACCTGACGTCCCCTGAGGCCTGGGCCCACCTCCTGACACCAAACGGGCCCCATTCGATCCGCAACACGCCCTACGATGGGGTCTTCATAGCGCTGCTGGTGGAGGAGGGCCACACCCACGATATCCTGGCCGCCGGATTTGACGGCATGTACACCTACTTTGCCTCCAATGGTTTCTCCTTTGGTTCTTCCCATCAGAACTGGAAAGCTGTGAAGAACTTTTGTGATGCCAACAACCTCATGTTCATCCCCAGTGTGGGGCCTGGCTACATAGACACCAGCATTCGGCCCTGGAACAACCACAATACGCGCAACAGGGTCAATGGCAAGTACTATGAGACGGCCCTGCAGGCGGCCCTGACAGTGAGGCCCGAGATCGTTTCCATTACCTCCTTCAATGAGTGGCACGAGGGCACCCAGATTGAGAAGGCCATTCCCAAGAAGACACCCACCCGCCTGTATTTGGACTACCTGCCTCACCAGCCCAGCCTGTACCTGGAGCTGACACGCCGCTGGGCGGAGCACTTCATCAAAGAGAAGGAGCAGTGGCTCATGTGAGGGGCCTGTAAATGGGCGTGAGGTGCTGATGTCCTTGCCTTGCTGGAAGATGTCACCATGTGGGGTTCAGCTGAGGTTGTAGCCACTCACTCGTTCCCAGGTCAGAGGTCAGCAGATGGGTGTTTCTGGGTGGGCCGTCAGGCATGGGCCTGTGCAACACAGAGCCCGTTCCTCAGGCGAGTGGTGCTGAGGTGCTCTGTGGTGATGGGAACGGCAGAGGCTGGCAGGTGACTGAACTTAGCCCAGGGCAGCTCCACATCCTGGGAACACTTTCATGTAACCCCTTCTAGTTTTGAACTCTGCAGCAGGCTGGTGCTGTGTAGTGGCCACCCAGTCACCACCCTTGGAAGGGTGTCAGGGTCTGGGCTCGCATGCACCCTGCTCCCTTCTGCCAGCCTGCATCCTCTCCTCAGGCCTCCTTCCCACATCATCTGTCTTCTCTAAGTTAGGGAACCATATTTGAGACTTTCAAAAAGGGAACTTCTAGGTTTAAGCTCCTCCCAGTAGATTCCTGAACCCAATTATCAGGAAATCATCCTGAGCACTCACAGGttcatttaacactcactcatcaagcaccttcctatgtgctaggtgctggggaaaacttgaccaaggaagagttcctgtcctgaagcttccagGACCCAGCTTTCCTTTTCTGGTGTGGCCTTGTAGCTAGTGCCTGGGCACAGGTGTTTTTCTTTTTGCAGTTTTACCTAGTGCTGGGAGTTCAGTTCTTTTTCCTCTAGAAAAATACCTCTGTGCTCCAGAGCCTAATTTTTCCCAGATGCATATTTAGCTCTAGGGAGAGGACTAGGAGGAAATCCCCCTCCCTTTAGCTGCCTGAACTGACTGAGGCCCACTCACTAGAGCCATGTTCAGTGCTACTGTGATTAGTAGTAATTAAATATGAACTGGTATTCTCAA

Publications

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