Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RRN3P4
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:142854181-142855997  UCSC
Coordinates (T2T) chr2:143302513-143304329  UCSC
Coordinates (hg19) chr2:143611750-143613566  UCSC
Strand +
Parental Sequence NM_018427.5_2
Parental seq. overlap 1541 bp
Parental seq. overlap (%) 41.2%
Genomic Region Intergenic
Retrocopy Summary RRN3P4, located on chr2:142854181-142855997, is a retrocopy of the parental gene RRN3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RRN3
Full Name RRN3 homolog, RNA polymerase I transcription factor
Also known as A-270G1.2|TIFIA
Coordinate chr16:15060022-15094335
Strand -
Gene summary Enables RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in transcription initiation from RNA polymerase I promoter. Predicted to act upstream of or within several processes, including DNA-templated transcription, initiation; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of transcription, DNA-templated. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RRN3P1
Bonobo Pan paniscus LOC117978922P1
Gorilla Gorilla gorilla LOC101142371P1
Gibbon Nomascus leucogenys RRN3P1
Green monkey Chlorocebus sabaeus RRN3P1
Crab-eating macaque Macaca fascicularis RRN3P1
Rhesus Macaca mulatta RRN3P1
Baboon Papio anubis RRN3P1
Golden snub-nosed monkey Rhinopithecus roxellana RRN3P1
Marmoset Callithrix jacchus RRN3P1
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RRN3P4
TATTTCAGATATGCTTGCATTCAAGAATGATTTTTCCAGCTCTCCCCCAAGAAAAATTGTTCATCTTGATGGAACGGGGACAGAAGTCTTGCCGAAGGACAAAGAGTGAAACAAATTTAACTTTGAGCTGTTGAAGAGCCAGTTGTGAGATTCAAACATAAAGGATGACCAGATCTTGAACTGGCTGTGAAAATTTTGCTCTTCTATCATGTACTTGGCAAAAGACTTTGAGCAGCTCCTCAGTATTACATTGAGATTGCCTTGGTTGAATAGAATTCAAACAGTGGTGGAAGAGTATTTGGCTTCTCTGGGTAGTCTTGTAACAACAGACTCTTCCTTAGCCCAAGTCTCAGCATAATTGCTTCCCATTTGGCGTACCCTCCTTGAATGATCATTAAGAAGAGCCATGTAAATGTTTCAGATTCTGATGATGGAGATGATTATCTTCCTGCAGATTTTGACACACGTCATACAACCTTACAAATAACAGCAAGATATGTCCCACTGGCACTGTGGTTTCTTTTGCCCATACTGGTGGAAACATTTCCATTTGTTCAATCAGAGAGAACACTGGAATGTTACATTCATAACTTACTAAAGATTAGTATATACTTTCCAACCTTGAGGAATGAAATTCTGAAGCTTATTATTAAAAATCTATTCAAATTGGATGTGAATACATTCTGGCATGATATTGAAGATGCTGAGGAAACAGCAGCTCAAACTTGTGGTGGGACAGATTCCATGGAATGATTGTTCAATATGAACGAAGATGAAGAGACTGTTTCTAAGGCTGACTCCAAATGGCTCGGTCAGATGGTGCACCCTGTAGCTGAATGCCTGGACACCCTGCTGTCTTTGCTTTTGCAGTACTTGAAGTATGTCTGCTATGTAAAATACATGGTAAGGTTGATAACAACAAAATAAAGGATTTATAATATATCACAAACTGATAAACATATTTGACAAACCCCTGCCTCCTGTCACGTACAGTTTTTTATGTTTTACCTCTGTGGCTTAAAATTGCGACTCTCAGAAGCATTTTTGGAACGTCTCTGGGAAAAAAAAATGCAGGATCCAAATAATCCTGTCATCATCAGGTGAGCTGCTGGAAATTATATTGGAAGCTCTTTGGCAAAAGCTAAATTCATTCCTCTCATTACAACTATAAAATCATGCCTAGGTCTTTCGGTTAACTGGCCACACAAATACCTTACTAACCAGGATCTGAGAATGAAGGCTTTTTGTGATATTGCTCTCCATCAAACATTTTACTCAGCCTTCCAAGCTGTGTTCCACACCTTTGTTTTTAGACACAAGCAACTTTTAAGCGTAAACCTGAAAGAAGGTTTGAGATGTCTTCAGTGCCTACATTTTTAAGGGATAGTGACTAGGCAGCTAAATCCTCTGAATATTTGCCTGCCCTCAGTGGTTAACTTATTTGCTGCTGTCACGAATAAATATCAGCTAGTCTGCTACACTATCATTGAGAGGAACAACGGCCAGAAATACAGCTGGAGGAGACTCGGTGTGAACGTGCACCAACCCATTGGACGCCTTCTTCCCCTTTGATCCTTGTGCGCTTAAGCAGTCAAGGAAAGTCATTGATTCTATTTATCAGATATGGGAAGACATAAGTGTCGAAGAGCTTCAGGAGTTTAAGAAACCTATGAAAAAGGAGATGGAAAAAGATGGAGATGATCTTTTGAAAGGTGAAGTTCCCCCAAATGATACCATGATCGGGATTATACCGAGCCACTTTGATGCGATGCACATTTCCAAAGTCCTTCAAGTAGTGTGGGCTCCCCACCTGTGTT
>NM_018427.5_2
ATCCGGCCTGAGGCGCAGCGGTCGCGTTAGTTCGGCCCAATGGCGGCACCGCTGCTTCACACGCGTTTGCCGGGAGATGCGGCCGCTTCGTCCTCTGCAGTTAAGAAGCTGGGCGCGTCGAGGACTGGGATTTCAAATATGCGTGCATTAGAGAATGACTTTTTCAATTCTCCCCCAAGAAAAACTGTTCGGTTTGGTGGAACTGTGACAGAAGTCTTGCTGAAGTACAAAAAGGGTGAAACAAATGACTTTGAGTTGTTGAAGAACCAGCTGTTAGATCCAGACATAAAGGATGACCAGATCATCAACTGGCTGCTAGAATTCCGTTCTTCTATCATGTACTTGACAAAAGACTTTGAGCAACTTATCAGTATTATATTAAGATTGCCTTGGTTGAATAGAAGTCAAACAGTAGTGGAAGAGTATTTGGCTTTTCTTGGTAATCTTGTATCAGCACAGACTGTTTTCCTCAGACCGTGTCTCAGCATGATTGCTTCCCATTTTGTGCCTCCCCGAGTGATCATTAAGGAAGGCGATGTAGATGTTTCAGATTCTGATGATGAAGATGATAATCTTCCTGCAAATTTTGACACATGTCACAGAGCCTTGCAAATAATAGCAAGATATGTACCATCGACACCGTGGTTTCTCATGCCAATACTGGTGGAAAAATTTCCATTTGTTCGAAAATCAGAGAGAACACTGGAATGTTACGTTCATAACTTACTAAGGATTAGTGTATATTTTCCAACCTTGAGGCATGAAATTCTGGAGCTTATTATTGAAAAACTACTCAAGTTGGATGTGAATGCATCCCGGCAGGGTATTGAAGATGCTGAAGAAACAGCAACTCAAACTTGTGGTGGGACAGATTCCACGGAAGGATTGTTTAATATGGATGAAGATGAAGAAACTGAACATGAAACAAAGGCTGGTCCTGAACGGCTCGACCAGATGGTGCATCCTGTAGCCGAGCGCCTGGACATCCTGATGTCTTTGGTTTTGTCCTACATGAAGGATGTCTGCTATGTAGATGGTAAGGTTGATAACGGCAAAACAAAGGATCTATATCGCGACCTGATAAACATCTTTGACAAACTCCTGTTGCCCACCCATGCCTCCTGCCATGTACAGTTTTTCATGTTTTACCTCTGTAGTTTCAAATTGGGATTCGCAGAGGCATTTTTGGAACATCTCTGGAAAAAATTGCAGGACCCAAGTAATCCTGCCATCATCAGGCAGGCTGCTGGAAATTATATTGGAAGCTTTTTGGCAAGAGCTAAATTTATTCCTCTTATTACTGTAAAATCATGCCTAGATCTTTTGGTTAACTGGCTGCACATATACCTTAATAACCAGGATTCGGGAACAAAGGCATTCTGCGATGTTGCTCTCCATGGACCATTTTACTCAGCCTGCCAAGCTGTGTTCTACACCTTTGTTTTTAGACACAAGCAGCTTTTGAGCGGAAACCTGAAAGAAGGTTTGCAGTATCTTCAGAGTCTGAATTTTGAGCGGATAGTGATGAGCCAGCTAAATCCCCTGAAGATTTGCCTGCCCTCAGTGGTTAACTTTTTTGCTGCAATCACAAATAAGTACCAGCTCGTCTTCTGCTACACCATCATTGAGAGGAACAATCGCCAGATGCTGCCAGTCATTAGGAGTACCGCTGGAGGAGACTCAGTGCAGATCTGCACAAACCCGCTGGACACCTTCTTCCCCTTTGATCCCTGTGTGCTGAAGAGGTCAAAGAAATTCATTGATCCTATTTATCAGGTGTGGGAAGACATGAGTGCTGAAGAGCTACAGGAGTTCAAGAAACCCATGAAAAAGGACATAGTGGAAGATGAAGATGATGACTTTCTGAAAGGCGAAGTGCCCCAGAATGATACCGTGATTGGGATCACACCAAGCTCCTTTGACACGCATTTCCGAAGTCCTTCAAGTAGTGTGGGCTCCCCACCCGTGTTGTACATGCAACCCAGTCCCCTCTGACGGCAGAAATTTGTGACTGAGATGTGACATTTGGGATTCCCCATCACTTGTCATGCCCTCAGCACCCAGCTTGTGCCATTGGGCATTGATGGCATTGAACTAGAGCGAGTGCCTGCCTCGGCTGTGGCACTTCCAGGTTCGACTGAATCAAGCATCTGAAGACTGGGTTTTTTTGTTGTTGTTGTTCCCCTTACAGACAAAATGAAGACTATCATGTGCAATCTTTTACAGTGGGGTTGATGATACATTTGGAAGGATTTGCTTGTTTAATATGTACATTTTTTGTGTTAACAGCTTTTTGACACAATTACTGGGTAATTTCTAATATAGGCAGCAGACTGTTTTACGGGTTGCTGTTTTAACATGGGTTTTTGTCAGATCCATGGTCTTAGGACTTGACTGATGAGCTTTCAGTGAAGAATCCTCTAAGATAAAACTTCTATTTAAAGACTTTAACTAGAAAGTGTTTATTTTGGCTACATTGTTCACCTTCTGCTGTATTGGTATTTGTCTGTTGGGATTTCAAGGGAGTGTAGAGAAGACAGAAGGAAAGCTGAGAGCTGGCCCGACATGGTCTGGGACACAGAGTTGGAGCTGGCACTGAAGATCTCCAGGGACTTCAGAGACCAATAAAAGCCCATAGGGAAGAGAGAGAGGATATAGGGAAACAGAATCAGATGTGTAATATACTTGGCACAGCGAAAAAATGGATTTAAAAGACAAAAATGGAGGTCCAGGTAGATGTAATTCACACAGACTGAAAGTGAGTTCGGGCTTGTGTAAAACACATGAGATTGGATTTGACCCCTTGGCTCTCAAGTGTCCCCTTAGATCTAGAACTGCTCCTTGGTGGCCATTAGATCGAGTCAGTTTTGATCTGCATCACTTAGTTATTGGGAATTTCTTTGTTGGAAACAGGAAAATTTTTTTAGATTATTTGGTGTACGGTTTTGCTCACAACAATAGGTGGAAGTTGCTAGTGCAGTCTTGGTCTGATGGCTGTGTGCATCGCACATTCGGCTTGGTGAAATCCTTCTCTAAAGCCTCTTTTTGTATTTTTATAACTAAACAGAGGAAGTCTTCAGAAGACCTCGCTTTAAAACAAATTTGTGCAAACACTGCTAGAGTCATTTTGAAGCTCAAGCATTTTCACTTTGTTTCTTACATGTGTACTTTTTTGTTTACTTGTGAAAATGGCCATCTTTAAGCATATTTATTTTCTGCCACTTTATTTAAAGGCAAGCAATATTTTCTTGATCATAAATATTTTGTAATGAAATACTTCCTCTTTTCCAGGGCTTTGTATGCACTTGTATAATTACATTGATGGCAATGTAGAGTTTGAATTTCAGTCTGTAAATACTTTTTTGGAAAATAGAAATTTTTATTGCTTTAAAGTTTTGGATATGGGTGGTTTTCTTTTCCGGGTTTGGTGGAAAGTAATTTGAGAACTTTAAGGTTGTCTTTTTAACTGCTGGCAAAATGTTGATTTTTTAATATTAGATAAAACGAGTAAACGAAATTCCCCAGAAATTAGTAGTAAGTGGGGTCTTTGTGGGTTGGGAAGTAGTTTTAATGTAGAAAGACATTTACATATAAGTCTGTTTAATTTCAAAGGAGTTTGTGAAAAAAAATCCATGGTGAAAATGAAACAATGACATGGTTAATCTGGAACTTACGTTCTTATACCAATAAAAGGTACCTCAATACA

Publications

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