Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name SGCEP1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:144754508-144756076  UCSC
Coordinates (T2T) chr2:145202522-145204090  UCSC
Coordinates (hg19) chr2:145512075-145513643  UCSC
Strand -
Parental Sequence NM_003919.3
Parental seq. overlap 1319 bp
Parental seq. overlap (%) 69.9%
Genomic Region Intergenic
Retrocopy Summary SGCEP1, located on chr2:144754508-144756076, is a retrocopy of the parental gene SGCE. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SGCE
Full Name sarcoglycan epsilon
Also known as DYT11|ESG|epsilon-SG
Coordinate chr7:94584980-94656205
Strand -
Gene summary This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2. [provided by RefSeq, Oct 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SGCEP1
Bonobo Pan paniscus SGCEP1
Gorilla Gorilla gorilla SGCEP1
Orangutan Pongo abelii SGCEP1
Gibbon Nomascus leucogenys SGCEP1
Green monkey Chlorocebus sabaeus SGCEP1
Crab-eating macaque Macaca fascicularis SGCEP1
Rhesus Macaca mulatta SGCEP1
Baboon Papio anubis SGCEP1
Golden snub-nosed monkey Rhinopithecus roxellana SGCEP1
Marmoset Callithrix jacchus SGCEP1
Mouse lemur Microcebus murinus SGCEP1
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SGCEP1
CCAATAATGCAATTGCCCTGGTGATGGTACCCTGCAGACCCCTGTGCTTGCATAGGACAAGTTCAGGGGACACGCGGGATGAGCCTGTGATGGTTGTCACATTCTTGATGACAGTATTCATTATTTTCTCTAAGGTGCACTCTGATCAGAATGCATACACATCTGTAAGTGTCCTTTTGGTGTATGCTTTGGAATGACTATTTTAGGAGAAATTTCCACCTCACCAAAACCTGGTGAGATTAGTGATGATCCCAAAGCATTTAAAACAAATTGAAAGGGTTATTCAGAAAGACCTGGATGGCTCCTATTCATCCAAAGAACACCATATAGTGAGAGAGTCCTTATGGCTCTCCAACAACTGAAAATGTGGAGAAACCAACTACCATTGATATAATTGCCTATAATAGGTGCACCTTTGAGACTGCAAGGCATAATTGGATAATATAATGTCAACAGAGGACTTCCTGTTGCCATATCAAGCAGAAATCTTCATTAAAAATATAAATGTGTAAGAAATATTGGCCAGAAAGGTTCTTGGAAACTTTGTCAGGGTGGAGAAAAATGTGCTGTGGCCAGAGGACTGAATGCCATAAACATCACATTGGCCCTAGATAGGGCAGCATGGTTCTGCTTCCTATTAATGGCCCAAAGGGGGACATTTTCATCAGGATTGGTGCCAATGTCCCATTTTCTTCTTGATTACAAGATGTTGAAAATCCATAGAATTCATTGAGATGCAGTCAAGAAATGGAGCCTGTAATAACATGTGCTAAAAAATTGTATATTCCGTTTTACATTGACTGGTGCAAAAATTCATTTGGTTGATAAAACAAAGCAAGTGGCCACCTATCCAGAAGTGATTCGTGGAGGGGGAATTTTAGTGATGATGGAGAGTACAAACTCTTTTCAAAATGACTGTCTGAAAAGCAGACAAGTACGTGGATTTCTTAATTATACTGGCTGTGTCCTCAGCAGTAGCTACTGGTCCTCTTTCTGGTACTTCCTTACATCATGCACTGTTGACAGAAAGGAGTAGAAAAGAGAAACATGCAAACATCAGACATCCAACTGGTCTGTCACAGTGCTATTCAGAAATTTGCCAAGGAGCTTCAAGACACATCCAAGAGTAGAAAGACAGCATGGCCCCCATCAACACTTCCTGTGTCTCACTTGTAACTGGTGAAATCATACCTTCCCTGTACACAGAGAACCATGATAGCACTAACACGCAAATGCAGCAGAATTTGTGACATCCAATTCAGGTTCCTCAACAACAAAGTACAAGTAAATGTCATCCCTGAAGAAGAGAACTGACCAAAGCATGAATTTATAATCAGACAATATAGCAGTTATATCACATTTCTTTTCACTTCCAATAATGCATAAGCTTTTCTGGTATATGGTGTGTATGTTCATGGTATTAACTGTAGAAGATATTATAATACAATATAACTTACATTTTACTAATGTATTTTTTACTTAAAGCATTATTGACAATTCGGAAAACACTGATGACTTTATATTTGTTACAATTAAAAGTGATCTTTAAAATAAATATTATTAATGAAA
>NM_003919.3
gagAATCGAGGACGGACGGCCTAGCCAGGCCAAGAATGCAATTGCCCCGGTGGTGGGAGCTGGGAGACCCCTGTGCTTGGACGGGACAGGGTCGGGGGACACGCAGGATGAGCCCCGCGACCACTGGCACATTCTTGCTGACAGTGTACAGTATTTTCTCCAAGGTACACTCCGATCGGAATGTATACCCATCAGCAGGTGTCCTCTTTGTTCATGTTTTGGAAAGAGAATATTTTAAGGGGGAATTTCCACCTTACCCAAAACCTGGCGAGATTAGTAATGATCCCATAACATTTAATACAAATTTAATGGGTTACCCAGACCGACCTGGATGGCTTCGATATATCCAAAGGACACCATATAGTGATGGAGTCCTATATGGGTCCCCAACAGCTGAAAATGTGGGGAAGCCAACAATCATTGAGATAACTGCCTACAACAGGCGCACCTTTGAGACTGCAAGGCATAATTTGATAATTAATATAATGTCTGCAGAAGACTTCCCGTTGCCATATCAAGCAGAATTCTTCATTAAGAATATGAATGTAGAAGAAATGTTGGCCAGTGAGGTTCTTGGAGACTTTCTTGGCGCAGTGAAAAATGTGTGGCAGCCAGAGCGCCTGAACGCCATAAACATCACATCGGCCCTAGACAGGGGTGGCAGGGTGCCACTTCCCATTAATGACCTGAAGGAGGGCGTTTATGTCATGGTTGGTGCAGATGTCCCGTTTTCTTCTTGTTTACGAGAAGTTGAAAATCCACAGAATCAATTGAGATGTAGTCAAGAAATGGAGCCTGTAATAACATGTGATAAAAAATTTCGTACTCAATTTTACATTGACTGGTGCAAAATTTCATTGGTTGATAAAACAAAGCAAGTGTCCACCTATCAGGAAGTGATTCGTGGAGAGGGGATTTTACCTGATGGTGGAGAATACAAACCCCCTTCTGATTCTTTGAAAAGCAGAGACTATTACACGGATTTCCTAATTACACTGGCTGTGCCCTCGGCAGTGGCACTGGTCCTTTTTCTAATACTTGCTTATATCATGTGCTGCCGACGGGAAGGCGTGGAAAAGAGAAACATGCAAACACCAGACATCCAACTGGTCCATCACAGTGCTATTCAGAAATCTACCAAGGAGCTTCGAGACATGTCCAAGAATAGAGAGATAGCATGGCCCCTGTCAACGCTTCCTGTGTTCCACCCTGTGACTGGGGAAATCATACCTCCTTTACACACAGACAACTATGATAGCACAAACATGCCATTGATGCAAACGCAGCAGAACTTGCCACATCAGACTCAGATTCCCCAACAGCAGACTACAGGTAAATGGTATCCCTGAAGAAAGAAAACTGACTGAAGCAATGAATTTATAATCAGACAATATAGCAGTTACATCACATTTCTTTTCTCTTCCAATAATGCATGAGCTTTTCTGGCATATGTTATGCATGTTGGCAGTATTAAGTGTATACCAAATAATACAACATAACTTTCATTTTACTAATGTATTTTTTTGTACTTAAAGCATTTTTGACAATTTGTAAAACATTGATGACTTTATATTTGTTACAATAAAAGTTGATCTTTAAAATAAATATTATTAATGAAGCCTAATGACTGGTGAAATTTACTTCAGTAAACTATTTGCTTCCTATTTAGTAGAAATCTTTTAATCGCTAGAAACAGGTTTATGTGTTCATTCTCATTCCACAAGACTTTAGTGCTTCCTATGAATATATAAAATGCCTGTGCCTCCGTGTTCCAGTTGAGCAACCCATTTAAATAATACTTTAACTCTTGTGGCCTGTAAATCCTGTTGTTTtatataccacttgggagtgttttcgaataaacctag

Publications

PMID - Link Title