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Summary

Retrocopy Name RPL26P43
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Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:147810387-147810771  UCSC
Coordinates (T2T) chr2:148260857-148261241  UCSC
Coordinates (hg19) chr2:148567956-148568340  UCSC
Strand +
Parental Sequence NM_001315530.2
Parental seq. overlap 329 bp
Parental seq. overlap (%) 36.4%
Genomic Region Intergenic
Retrocopy Summary RPL26P43, located on chr2:147810387-147810771, is a retrocopy of the parental gene RPL26. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RPL26
Full Name ribosomal protein L26
Also known as DBA11|L26
Coordinate chr17:8377516-8383193
Strand -
Gene summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RPL26P9
Bonobo Pan paniscus RPL26P9
Gorilla Gorilla gorilla RPL26P9
Orangutan Pongo abelii RPL26P11
Gibbon Nomascus leucogenys RPL26P24
Green monkey Chlorocebus sabaeus RPL26P14
Crab-eating macaque Macaca fascicularis RPL26P24
Rhesus Macaca mulatta RPL26P25
Baboon Papio anubis RPL26P24
Golden snub-nosed monkey Rhinopithecus roxellana RPL26P37
Cow Bos taurus RPL26P1
Sheep Ovis aries RPL26P1
Dolphin Tursiops truncatus RPL26P8
Horse Equus caballus RPL26P1
Dog Canis familiaris RPL26P10
Cat Felis catus RPL26P10
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Panda Ailuropoda melanoleuca Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>RPL26P43
GAAAAGTCATTTCAATGCACCTTCCCACATTCACAAGAAGATTATGTCTTCCCCACTTTCCAAAGAACTAAGACAGAAAAGAAACGTTCAATCCGTGTTCATCCAAAAGGATAATAAAGTACAGGTTGTCCAAGGACACTACAAAGGCCAGCAAATTGGCAAAATAGTCCAGGTTTAGAGGAAGAAATATATGATCTACATTGAACCGATGCAGCAGGAGAAGGCTAATGGCACAACTGTCCCTGTGGGAATTCACCCCAGCAGGATGGTTGTCACTAAGCTAAAACTGGACAAAGAGTGCAAAAAGATCCTTGAACCGAAAGGCAAATCTCACTAAGTACAAAAGGGAAAGGACAAATTCAAGGAAGAAACAATTCAGAAGATG
>NM_001315530.2
CTCTTCCCTTTTGCGGCCATCACCGAAGCGGGAGCGGGTAAGGATTCGGCGGGCAAGCGGGTGTAATCAGCAGCCATCCGTTCTTGGGCATGGTGGCTTCCGACCGCGGGGACCCCGAGAGTCTCTTGTCGGCCGAGTAGCAGCCAGGAAGGAGAGACTGGGATGGTTTTTTATCTGTTGCTTTCTTAAATCAAGGGCCGCCGGGCCGGAGATGGATGGAGGGACCGGGGATTTGGGAACTCGAAAACGAGCTGAGGGAAGGGAGCCTGTGGAAATAGACTGGAGTCTGGGTAGTGTCGTTTCCTAGAGAATGGTCTCGAAGTAACTTCTCGGTAAAGTCTTCACGGAATTTCCAGACCACACTTGCCCACTGGGAGGCTTTTAGGACCCGAGACGTGTGCAGGCTTTTCCAGCCAAAATGAAGTTTAATCCCTTTGTGACTTCCGACCGAAGCAAGAATCGCAAAAGGCATTTCAATGCACCTTCCCACATTCGAAGGAAGATTATGTCTTCCCCTCTTTCCAAAGAGCTGAGACAGAAGTACAACGTGCGATCCATGCCCATCCGAAAGGATGATGAAGTTCAGGTTGTACGTGGACACTATAAAGGTCAGCAAATTGGCAAAGTAGTCCAGGTTTACAGGAAGAAATATGTTATCTACATTGAACGGGTGCAGCGGGAAAAGGCTAATGGCACAACTGTCCACGTAGGCATTCACCCCAGCAAGGTGGTTATCACTAGGCTAAAACTGGACAAAGACCGCAAAAAGATCCTCGAACGGAAAGCCAAATCTCGCCAAGTAGGAAAGGAAAAGGGCAAATACAAGGAAGAAACCATTGAGAAGATGCAGGAATAAAGTAATCTTATATACAAGCTTTGATTAAAACTTGAAACAAAGAGCCTG

Publications

PMID - Link Title
No publications available for this retrocopy