Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HEBP2P1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:156033106-156034080  UCSC
Coordinates (T2T) chr2:156485773-156486747  UCSC
Coordinates (hg19) chr2:156889618-156890592  UCSC
Strand -
Parental Sequence NM_014320.3
Parental seq. overlap 473 bp
Parental seq. overlap (%) 4.7%
Genomic Region Intergenic
Retrocopy Summary HEBP2P1, located on chr2:156033106-156034080, is a retrocopy of the parental gene HEBP2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HEBP2
Full Name heme binding protein 2
Also known as C6ORF34B|C6orf34|PP23|SOUL
Coordinate chr6:138403531-138422197
Strand +
Gene summary The protein encoded by this gene is found predominately in the cytoplasm, where it plays a role in the collapse of mitochondrial membrane potential (MMP) prior to necrotic cell death. The encoded protein enhances outer and inner mitochondrial membrane permeabilization, especially under conditions of oxidative stress. [provided by RefSeq, May 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HEBP2P1
Bonobo Pan paniscus HEBP2P1
Orangutan Pongo abelii HEBP2P1
Gibbon Nomascus leucogenys HEBP2P1
Green monkey Chlorocebus sabaeus HEBP2P1
Baboon Papio anubis HEBP2P1
Gorilla Gorilla gorilla Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HEBP2P1
CAACTTTTGACATTAGCAAGCATTTAAGCATTTTGAGGGAAGAAGGAAAAGTTTTCAATAAAAAGGTTTATTACACTGCAGGCTACACCAGTCCTTTCAAATTGCTTAATAGAAATAATAAAGTTTAATTGATTGAGAAAAAGGAGTCCTCCAAAGAAAATGAATGAGAAAAGGAAAGGAAGTTCCACTGCCGGGGGAAAGCTTCTGTTTAACCTAGACATTAACACTACCTATCATAAAGTGTGTGTCTAGCATCTTTGTGAGAGCACTACAATGACTCAAGCTCATTCCCAATGTGCCTTTTTAGCAAGCTGTGGACACTGGGCTGGAAGGCCCCAGAGGTTGGAAGCCCCCAGCTCTGAAGTCATGGGATCTGACAGTGTGGACAGTTAAGTGGGTCAGCACTTCTGTTGAGTCTATGAACAGGGGTTCAGCCATCCAGACAGGCTTTACAAAACTGAACATCTACATTCAAGGCAAAAGGAGAAAGAGATGAAAATAATGGTGACAGCTCCAGTCACAAGCTGGACCAACCAAAGGTTGGTTCATGTCCTTTTAGTGAGTCTACCAAGACCATTTCCCTGTATATCTCCTCTGAACAGCAATTCCATCTGCCCAGGCCTTCAGAGTCAGATGACTTTATTGAAGACACAGCCGATATGCTGTGTTTCATTCAGTGGATACTCTAGTGCCCCAAAGAATCAAGAGCAACTTCCc
>NM_014320.3
CCCTGTCGCCGCGGAGGGGCGGGGGCAGGACGCGCAACTCCGGCCGGAGCTGTCCGGGGTCGTGAGCCGGCCCCGCCTTGGTGGCGGCGCCCCCTCGCGGTCCAGAGGCAGACGCATCGGGTGGGCTCGGGTCTCCAGCCCGGCCGGGAGGAGGGACCGGGTCTGCGGAGCGGGGACTCGGGGCCTCGGCGGGGCGCGCACACGCAGGCGGGGCGGCCCGGGGTGCGGGGCCTCTGCGCGGCTGACCAGGCTCCCAGAGCGTCAGCGCCGCCCATGGCCGAGCCGCTCCAGCCAGACCCCGGGGCGGCCGAGGACGCGGCGGCCCAAGCTGTGGAGACGCCGGGCTGGAAGGCCCCGGAGGACGCCGGCCCCCAGCCCGGAAGTTATGAGATCCGACACTATGGACCAGCCAAGTGGGTCAGCACGTCCGTGGAGTCTATGGACTGGGATTCAGCCATCCAGACGGGCTTTACGAAACTGAACAGCTACATTCAAGGCAAAAACGAGAAAGAGATGAAAATAAAGATGACAGCTCCAGTGACAAGCTACGTGGAGCCTGGTTCAGGTCCTTTTAGTGAGTCTACCATTACCATTTCCCTGTATATTCCCTCTGAACAGCAATTTGATCCACCCAGGCCTTTAGAGTCAGATGTCTTCATTGAAGATAGAGCCGAAATGACTGTGTTTGTACGGTCTTTCGATGGATTTTCTAGTGCCCAAAAGAATCAAGAACAACTTTTGACATTAGCAAGCATTTTAAGGGAAGATGGAAAAGTTTTCGATGAGAAGGTTTACTACACTGCAGGCTACAACAGTCCTGTCAAATTGCTTAATAGAAATAATGAAGTGTGGTTGATTCAAAAAAATGAACCCACCAAAGAAAACGAATGAGAAAAATGAAAGGAAGTTCTGCTGTCAGAGGCAAAACATCTGTTTATCATAGACATCAACATGACCTATAAGTAAAGTGCGTGTCTAGTGTCTTCTATTGAGAGTACTACTATTAATTAAGCTTATTTCCAATGTGCCTTTTTAATGCTTGAAGTTTTATCTACATACACAGGTAACAGAGGACAGTAGTCTGTAAACATATAAATCGGTCATAACTATCGTGGTCTTTATTTCTGTGAGGATCTAGGGAAATTTCATGTCACTTCCCTCCTTCACTGCATCACAATCATATTCCCTTTTTTTTTTCTTGGATTTGTGTCAGTTGGATGATATCCCCTCCAGATAGTATCAATAAAATGTTAAAATTATTTATCTTGTGTGGAACCCCTAGGCTGTCAGGCCCGGAGAGGTGAAATTCAGCTGGACACAAAAATCAAATTGTCTTTTGTGGCTGCCACCATTACATTCTCTGTTGTATGTATTACTTTCCCTCCTGCATCCTCCCACTGCCCCACTGCACAAGAATACTCCATGTAACTCCATTTAAATGTAATGAATTCATTCCTTTCTTTCTGGTCTCCACTTAACCCCCTAAAAATCTTGCTTTTTCCCCTAAACATTTCCCTGAACTGTCACGTATTttcattcattctttaactcattgtagggagtccctgctatgttccaagcactctgctaaggactgggaggtggtggtaagaaaacctgtgtcccaagcccctcaTCACTGACTTCCTCTTCACTAACTCCAACAACATCTTTCCACCTCCTTAACTATTTCATTCACCCTCCCACTgtgaacaccacagacaaggcccctggcctcatggagtttacattctagagggtgagggagttcaacacaaataagatgcttgaaattggcaagtgtgatgaagaacagaatagggcagtggggtagagtgtggttaggtagggtgtggtggacatcacataaggtggtcagcaaaggcctctcaagagacagttgagacttgaatgacgaggatgagtcagatgaaagccaggggcagaggtgaggggagcatcttgggcagaggtgacagtgttaaagggagaggccACGTTCAGTACCCAGAACAAAAAGCTGCACACACTGCTTGCTGAGCAAGAGAGCACTGCTCTTGTAGGGCACGGTCTCTCGGATAAAGAAAACTGCGGACCTTATGCAGGGTTTTAGGAAGGATTAACAGACTTTCAAAAGCATTTAGGAGTCGAGGGAGCTTTAGTTGTGGGGATGCAGTTACCAGAGTGAGGCCGCTGCTGATTAGCATGATTTAGAAGCCTAGTTTGGAGGTGAGGTTACTGATGGGAAATTGTCATTGATTGTTTCTGGTACTTAATTGCTACTGTGGCCAAAGGATGGTCAGTTTTATTCAGGATTTGAAGTGgtggcagacaacgtgaggtgtgccactcaaattcaccttcaagaaagtaccagccgcccagctgtgaggggtgtggttcgccgacagtctccccgttaccgtcttcagggtccacgccagatttcaagataaggacacactattctgtgggagagagggacctagtctacaactgagcaaggcagtggtagctgacagcatgcttttttctggcaattcccagccaataactgagcaaggtggtggtataagacctagccatttaggccaggtgcagtggctcacagctgtaattccagcactttgggaggctaaggtgggaggattgcttgagcccagaagttcaagacgagtcatggcaacctagtgagactgtctgtccaaaaaataaaaaattagccaagcgtggtggcacacgcctgtattcctagctcctgaggtgaaaggattgcttgagctcgggaggcggaggttgcagtgagtcctgatcatgccactgcactccagcctgggtgacagagcaagatcctgtctcagaaagaaaaaaaaaagtcctagtcatttctaccaactcgaaagccctctaataagcagtctctgctctggagctttttggtgggctgctagagactttgttagatcctaccgttcctctgctcaatcctgcttttcccttttcctttcagagatgtcacttcaccagttttgtactcctaactccatctcagcCTAAAATTGGCACAATTGGTACCAGTGGCCCACGAACGTAGGTGGTAAGACAGCATTTGCAGGCTGAGTGACTCACTGTCTGGCTGGCTCGGAGGCCCCCATCCCTGGTGGATAGGTGGCACAGACAGTCcctggcacaagaaggctgtccagtgatgaagacttcagatgaaatggcatgctggtgcaggggaacgcaatgactggtgggtgatttgggtgtctcaaatatgggaagggtggataaaagagacaaggacagtgggcttccatggttattgctgagttggattgacgtcctgcaagtggataatgaaaagctgaggtcaattaacaaacaaaactaagtgtgagccgcagagtctctgtggtagcttgccaacaatcctcatctcatgctgtagccaagcagagcaagctgaaggccaagcacaggatttgatggtaaaagtagctaacagccaacaaatactcaaccaagccaggtctgttagatcaaggttggaatcaaacttgggatcccaaaacatgggatgggagcatttagtggatctccccaaccatctgcctccctagaaaactccctgaatattcacatccttcagaagaggcccacccttccccatgaagagctggaactaccctcccttcctgcctcttccctaacacaagggaagacagtgtccaaggtctttccccatgaagcaaaaggtgtccctcaggactggtccctccccttctcctggctaccaggcctataacgagacttaagtcacaacataactgattgcggctgaggggtctgatgagggagaaatgggatctatgccagaggagccacctaacctggcagcatgtactgcaggggccaggggcgtactcttgggactggatcctgagggtgcttggtcaaaggggctgggtttatacaactagataaaggagagggtatattgacttggggctctcaggatagaggatttcacaccatgagaaaaatgccaggagataatacagactcactgctctagggcagcttggtagaagcctagaaagagtgatcaaaatgttgaaatgcctgaatggctgggacaaacaatagagaaaggaatgagaaggctcagggaagggagcatgccagcatggatatatgaggcaaggtgacccatcagacaattatgttccacgggaaggcccaggggacccatccttcagcaaggctgctgggaatgcactgataagcgggcttgggcatcataaaggagctcagcggtggctctcctcggcaggctggggctggcaggaagggctgtgatggaacttcacttgctgagagcaatgtggatgatgatgagaccttgaagagcccaggtggcagtgccagccacagaagccagggtgccatcagtatcctgttaaccactaagctccaaatggcagccgaggggtcctgacctgtaaagtctcatggaaatagttggtagaacaaggcattcctagggacaaaagagctgactaatcaacaagggtaaggctttatatataatcaaaagtgagcaagaattgatgagcaggggactgagagagatcactccaattaaaaaacaaaaacatgattccttgccagtttctagttcagttttctgacctagagctcattaattgcagaggtgactgtatcctaggggaaagtttcctgcaacatttcagcaggtgtacacagtaatgatcccctcattctttttctaaaggatctatggccatttactcaggtggctctaccctggggaaagaggaatacctggatacgtcagggtccaagttaacgtctgatacccagaaacccaaagagtcattacagttcctcctcctcccattaaaatgggagcatacagaggttagaaagtaaacgtagttctaatcaaagtttggcttacagcagatctcctgggcctgcaggttatctgcctaatccctgaatgtataattgagactgacatccttggcaggcagaataacccctacatttgttccttgacctgtggggaaagagTATAAGCTTCTAAACTCCCTCTCCTCCAATCAGGGCAGTAAACCATAATAAATATTGCCTTGAACAGTATTTTTTAAGCACCTCGGGTGAacatctgcttctggccatgatgatgaattgggaacccaatttacctgtccctcttaaacaactaaaagcccagacaaaatatatgaaacaatggttttcagacactgaaagttcatagtacaggactgtgatctctgcgagaagggggaataatgaggtgagtccagtgattgctcaggcgaatggcctggaggcagtttctaggcagcaaagcagggagagggaagccagagaccagtggtcctgctgtgttgaggagatggagatcagtgtcaccggaggccaaggtgagtaagtgagaggagaggaggcagcagcacacagacagagagtgctgtagatctgcagtgggtcccctggagtccttggttgagtgaaggtgttagaagaaactacttaagccaagaaatgagtaactggaaattagtagagcaaataatttacagatcatctatggggctgggaaaagtttgtgtttccactagccagagtagaaataactcataatgcatgggtcatcaggtggagtcctccaacaggtgttgccttagtactgaggtcaaattgtccctagaccaaaggcttctttggacttcccctaacaaagcttaaagacaagccttggaaggatcaaactaatttcaagaaacttaactgtgaatcagaataaaacccaataccatttataggaatataacaaaatccatcaacaaacaacataacactcataattaccaacattcagtaaaaaattactggaaacagagaaatataaattatggcccataattaggaaaaaagggtaatcattagaagtagaaccagaagtgacaGATATGAAGAAATTAGCAGcttgaattatgtgatgtggcagatcttatgtattggaggtagggggaaagaagatgcagtgtggaatagatgacaaggcccaatgagagaatcacagtgcaggtccctggggccctgaaggaaggtggttctaaccacaggagaggatcatatgctttttgaaaaacagcctctgctgtgctactgggccctggtagacacggaactttgagacccagtgatgctgtatccagaactgctcatcttaactaggtcctgtgggaagcactaagtcataagctagtaggatcggcagcagcccattggaagatggaaatgatatgtacaggagcagttccaagccagaccagaggacataagcaaactgcaagagcaattactccaaccgccatgtctgcacagtggcacctacatcccccctccctgtggttgttggaggacctgtatgatccactgaaggaagaggaatgcttgggcttggtttattgattagttatcttctgtagttgcaagctgaaaatggaccttcactcaaaggtgacattgaaaaacgggaaaaaaattgcaatcttcctgcaaaaactgggcagaattttttgaggtacactggatcattcaccttgtgagggaggacaggtaaaatatttatggaagtggcagaaaatggcctgccagctgatcaggagtttgggaggaaaaaaacatggattaggaggtctggggtagaggcatgtggatgggcatatggagtgaacacagaagttgaaaaactgtatcacatgttaatgcccactagatagcacccaccagagaagaggcactaaacaaccaagtagatgaaatgacttagcctgttctattagcttttgccagtgcccacctcagtgctggtaaaatgcacacataaagtggcagtggtggcaaagatggaggctatggatggaacccaccaacatgggctcccacttaccaaggccaacttagacactgctcactgtgactatccaacctgcctgcaacaaataccaatgctgagaccctgatgaggctgtgaagaccaactggtcgcttgatagcaaattcactatggtaggctcattctttcctagaagcaccagcagtttattcacacaaggacagacttcctattctaggtatgtggttcctttcgggcctacagggtcctgaacacaatctaaggacttacaaaacatctgaactgtcagcgtagatttgctgaatacgtgatctatacatgttaacacccaatcagggagagttcgccagcggtcataggatccactgctcctatcacatactgcgccacctagaagctgctagactgatggaatgttggcatggcctgctttagtgccaggtgggagacaataccctgccaagatgtgccaccgtctcctgcacacagtatacttattgaatcagaaagcctgtatgatgctgtgtctacaacaggaatatatagatttcagaaccaaggagtggaggcaggagtgaccccacttaccatcgcacccaacgaaccactgagggacttagtacttcccatgcccacaactccaggttctacagcatcagaagtcctagttctcagagactgtataccttctctaggcaatattgcaagaatcccattgaactacagtctgctgctactatgtgggcactttggactctgtgttcagggaccagtaggcaagaagtcaccatctagtcaagggtaattgaccctgaactgcaggaggaggcaagcctgctgtcagaggatagtggcgagagcaatgtgtgtggaacttagcggacccactggaggcaccctctgtactccttgcccagttgtaactgaatggactagtgcagcaaccctggtctgagaagggtttggctcccaggagctcaggaccctcaggaatgagagcttggtttatactatcaaaaaagccaccaagaccagcaaagatgacagttgtgggtgaggggaatttagaatgaagcagggagtaatgaggaccagttgtggttccaaaaccatttgcaggaaggtgctatagttggtcctaccaaactcctctttcaacatttatcctcaggaagagaggtccattggcgccctgaaacagtcactctctgcgtgtttttgggaaaatggatccacataggcaaggggtggacCAtggcaggcatagagcggtgccacttagatcccccttcaagacaagatatgccatccagctgcaaggagtgtgggtagctggcagccaccagctgctacttcaccaggatccaccttagctttcaagctgaggtcacgctattctcaagacaggaggggttggtggccaatgatttcactaaattatggaaattgagagcatgcttttctgagggggccctcttgccaaagaccaagcaaggccatggtacaaggacctaactgtttcagtccaacacaggactcctccaatgagtgacctttttcccagagttcccctgggatggcagctcgcctgctctccctgcctcgtcctgcttcctcttttcctttcaaaggtgcttactccaataataaatcctttggtattctaactgtctacttcttgaagaatctaaactggcaGTAGGATCATGCCCCTCACTGATAGCTCAACCACGTTTTCTATCTTTGGGCCTCCTTGTCTTTACCTAGCACATGAGAAGCATTTATTAGGACTTTTTTTCCCCCATTGCTGAACAAATGACTACAGATTGCTCTACCTCTTGTTCTGTGAATAAAGGCTGGCCGCTGTGGAAGGTAGGTCAGAGCAGGCAACTGAGAGAAACTGTATTACAGTTACCGAGTGGCTTATTAAGGAAAGTGGCGCAACAATCAGGTCCATGTTTCATTCAAATGACCCTCCATTCCCCCAACAACATCCTCACATCTGCCAAAGCAAATTATGCTGCTGTGCTCATTTGATGATGGAATCAGCATCGCATGCAGGCTGAACCCCTACTACGGCAGAACCAAGAAAGCCACTCTTTCCCCTCTCCTCCTAAGATGCCACCACAGAGCAGGGTGCCAGTGGTGGGTGGGGAGAAAGACGGAGACACAGAAACGTCTCCTTTTCACTGTGATTCTCCTAAGGAATATACAGTCACCCCCACAGGAAAAGCAAGAGTTCAATCAAGATTCTTCAGAAATAGTAGGATGGCAGAAAGCAGATCGCATTGAGGTTGTTTCCAACTGACAGACCAAGCAGTAATTTGTTTCTCTCCCCACTGATAGTAAAAATAAAGTGGAAATAATTTAGGGCTGGGGCTTCTGTGATTATCTGGAACTTAAAGTATGAGGGTATGAGAGCCATCAGATCTACCCCTGTGGAGCTTTTTAAGATGCGGTCCATAACAGAAGCGGGCCCCAAGGAGTAGAGTAGCCACATGGAAGGTGCCATGTTTCAGGGATGAGTCTCGATTCTTCTCTCCCTGTATTTCATCCATGCCTGTAAGAAGTTCTCACGTCTCTCCACATGCCACGTCATCTGAACCGCCAGGCGATAGGTTATTCGTATTTTATTCCAAAGTCCATAGGACACGATGTGGACTTGTTTTTCCACGTGCCCTTGTAGATGGTGCCATCCAGTGTCTGTGATGTTCCACCTCCTCTGTTGGGTTGTCACCTCCCCCAGAGACCTTCTGGTCTCACTGCTTTTCTGTTTGTATCCAGCAAAACACTCAACAATTCTGTATAAGAACACCTATCTCATTATTCAAAAAAAATGCATGTATAAACAAAAAGAAATATTTCAAATATTTACTTTACAATTGTTTTATTCAAAGGAAATTAAATACAAATGTATATTTTTCATTAAAAATGGGGATTTAAAAATAGTTTTATAATTAGTGTTATGTTGCTTTATCTTATCTTTGCATAAATTATGTATTATTAAAGGTTTCTGATATCCATA

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