Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CAPZA1P2
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:159460930-159463269  UCSC
Coordinates (T2T) chr2:159918144-159920483  UCSC
Coordinates (hg19) chr2:160317441-160319780  UCSC
Strand -
Parental Sequence NM_006135.3
Parental seq. overlap 1655 bp
Parental seq. overlap (%) 57%
Genomic Region Intragenic (BAZ2B)
Retrocopy Summary CAPZA1P2, located on chr2:159460930-159463269, is a retrocopy of the parental gene CAPZA1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CAPZA1
Full Name capping actin protein of muscle Z-line subunit alpha 1
Also known as CAPPA1|CAPZ|CAZ1
Coordinate chr1:112619775-112671616
Strand +
Gene summary CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CAPZA1P1
Bonobo Pan paniscus CAPZA1P1
Gorilla Gorilla gorilla CAPZA1P1
Orangutan Pongo abelii CAPZA1P1
Gibbon Nomascus leucogenys CAPZA1P2
Green monkey Chlorocebus sabaeus CAPZA1P1
Crab-eating macaque Macaca fascicularis CAPZA1P2
Rhesus Macaca mulatta CAPZA1P2
Baboon Papio anubis CAPZA1P2
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CAPZA1P2
CTTCCAGGCAGTATCTTTCTATTGTAACCTGTTATTTAAGGAAATACTAACGATTTCTTCTAAATAGGATGTAAAACTTATTTCAGATTACTCTTCCTCAGTCCTGCCTGCCAAGAACTCAAGTGTAACTGTGATAAAATAACCTGTCCCAGGTATATTGGCAGGTATGTGTGTAATCTCAGAATACACAGGTGACATAGATATAATATAACAACTGGTAATGGTGGATTCATTTACATTGCTTACAGTTCTATGACCAGGCCTTAAGGGAAGGTCAGTTTAAAAAAAAAACAAGTAATGTCTTCCTGCCTATCTCCACATACATGTAAAAAAAAAACGTGTTTGTGCTTCAGTTCTGTTTTTGCTCAGTAATATAGTCAAGGAACAGTTTGTTTCCAAGTACCCATTGAGCTGTGTATGCATTTTTGTTTATTTCAAATAAAATATATTTGTATTATTTGTCATCCATACTATCCATCCATACCACACTATCTTCTGTATGAGATAGTCTAATAGAAATATACCTGTTTTGTTCTAAAATAGAACAGCCCAAGATGGCCAACTTCAATGATTGTGTGTTGGATAAGGAGAAGGTATGCATAGCTGCTAAATTCATCACTCATGCACCCGCAGGAGAATTTAATGAAGTATTCAGTGATATTCGGCTACTATGTAATAATGACAGTCTCCTCAGGGAAAGGGCAGCACGTGCATTTGCCCATTATAACATGGATCAGTTCACACCCGTGAAGATGGAAGGATGTGAAGATCAGGTCATAATTACAGAGCATGGGGGACCTGGGTAATAGCAGAGTTTTAGATCCAAGAAACAAAATTTCCTTTACATTTGATCACTTATAGAAAAAAGCAAGTGACCCCCAGCCAAAACAAGTAGATGGAGGTCTGAAGTCTTGGAGAGAATCCTGTGACAGTGCTTTAAGAGCCTATGTGAAAGACCATTATTCCAACGGCTTCTGTACTGTTTATGCTAAAAACTATCGATGGGCAACAGACTATTATTGCATGTATTGAAAGCCATGAGTGTCAGCCTAAAAACTTCTGGAATGGTCGTTGGAGATCAGAGTGGAAGTTTACCATCACACCACCTACAGCCCAGGTGGTTGGAGTGCTTAAGATTCAGGTTCACTATTACGAAGATGGCAGTGTTCAGTTGGTTAGTCATAAAGATGTACAGGATTCGCTAACTGTTTCGAATGACGCACAAACTGCCAAGGAGTTTATTAAAATCATAGAGAATGCAGAAAATGAATATCAGACAGCAATTAGTGAAAACTGTCAAACAATGTCAGATACCACATTCAAGGTCTTGCGCCGGCAGCTTCCGGTTACCCGCACCAAAATTGACTGGAACAAGATTACTCAGCTACAACATTAGCAAAGAAATGCAGAATGCCTAAAGGCTGAATGTAGGATTCTTCAGTATGTGGAAAGACAAGGATTCAACATGTGGTCATATGATAAATAAGTGATTTATAAACAAGAGTGATATTTTGCTAGAGCTTTCAAAGTTAACCAGTTTTCTAACCTCATGGAATACTGTTGAACCTATAGCATTGTCTGATTCTTTTGTGTTCTCTGCTTTGTAATTTTCTGTTATTGCTATATCCAAGTGTAAGTCTTTTTTTTTTAATTCTGCCACATTTAATGTTGGAGAGAGAGATCTATCCTAGAGACATTTTACTGTTTAAAAAAGTTTCCTAGCCATGAAGCGCTGCTACTGATTTAGACAAGGTATATGGTCATTACTTTCTACCCCTATCCTTCCAAGCACTTCTGATACTGCAGTGGTTTTTACTGATCCACCAGCACCTAAAGAGGCTGTACTACAGTCTATAGCTAAGTGGAAGGCACATTCATCCTTCTCCCTCTGACTGCTTTGATCATCATTTATTGCATCGCAGAACTGTAATTTTCCAAAGTTTGGATTGGGACTTTTCAGGTCCTTTTTGGAGGGCAAAGGAAGTGTCAGCTTCTCTGGGGAACTTGTTTTTAAATCCAAAGACTTGAACCACATTCCCTGCACTTGAACACGTTTGCTTTCATCCCTTCTCTCATTGTCTCCTTCCCATCTTAGTACCATTGTAGTTATAGACATCTGCATTTTTAGAAGAGTTTTAGCCATTTATTTTTTTAAACAGTCAAGAACTGCTGACATACTGTGGATATAGAGTATAAAACTTGAAAAATGCAGATGTTGAAGGAATAACAGGTATCTTGTGCTTTAATACTTTATGGCAGGATTGTACTATAAGCAAATGAATTAAACAGCTa
>NM_006135.3
AGAACAGCCCAAGATGGCCGACTTCGATGATCGTGTGTCGGATGAGGAGAAGGTACGCATAGCTGCTAAATTCATCACTCATGCACCCCCAGGGGAATTTAATGAAGTATTCAATGACGTTCGGCTACTACTTAATAATGACAATCTCCTCAGGGAAGGGGCAGCACATGCATTTGCCCAGTATAACATGGATCAGTTCACGCCTGTGAAGATAGAAGGATATGAAGATCAGGTCTTAATTACAGAGCACGGTGACCTGGGTAATAGCAGATTTTTAGATCCAAGAAACAAAATTTCCTTTAAATTTGACCACTTACGGAAAGAAGCAAGTGACCCCCAGCCAGAAGAAGCAGATGGAGGTCTGAAGTCTTGGAGAGAATCCTGTGACAGTGCTTTAAGAGCCTATGTGAAAGACCATTATTCCAACGGCTTCTGTACTGTTTATGCTAAAACTATCGATGGGCAACAGACTATTATTGCATGTATTGAAAGCCACCAGTTTCAGCCTAAAAACTTCTGGAATGGTCGTTGGAGATCAGAGTGGAAGTTCACCATCACACCACCTACAGCCCAGGTGGTTGGCGTGCTTAAGATTCAGGTTCACTATTATGAAGATGGCAATGTTCAGTTGGTTAGTCATAAAGATGTACAGGATTCACTAACTGTTTCGAATGAAGCCCAAACTGCCAAGGAGTTTATTAAAATCATAGAGAATGCAGAAAATGAGTATCAGACAGCAATTAGTGAAAACTATCAAACAATGTCAGATACCACATTCAAGGCCTTGCGCCGGCAGCTTCCAGTTACCCGCACCAAAATCGACTGGAACAAGATACTCAGCTACAAGATTGGCAAAGAAATGCAGAATGCTTAAAGGCTGAATGTAGGATTCTTCAGTATGTGGAAAGACAAGGATTCAACGTGTGGTCATATGATAAATAAGTGATTTATAAACAAGAGTGATATTTTGCTAGGGCTTTCAAAGTTAACCGGTTTTCTAGCCTCATGGAATACTGTTGAACCTATAGCGTTGTCTTGATTCTTTTGTGTTCTCTGCCTTGTAATTTTCTGTTACTGCTATATCTACGTGTAAATCtttttttctttttttttttttttttttGGTTAATTCTGCCACATTTAATGTTGGTGAGAGAGTGATCTATCCTAATGACATTTTACTGTTTAAAAAAGTTTCCTAGCCATGAAGCCCTGCTACTGATTTAGACAAGGTATTATGGTCATTACTTTGTACCCCTATCCTTCCAAGCACTTCTGGTACTTCAGTCGTTTTTACTGATCCACCAACACCTAAAGAGGCTATGCTACAGTCTCTAGCTAAATGGAAGACACATTCATCCTTCTCCCTCTGACTGCTTTGATCATCATTTATTGCATCTCATAACTAATTTTCTAAAGTTTGGATTGGGACTTTTCAGGTCCTTTTTGGAGGGCAAAGGAAGTGCCAGCTTCTCTGGGGAACTTGTTTTTAAATCCAAAGACTTGAACCACATTCCCTGCACATGAACATGTTTGCTTTTATCCCTTCTCTCATTGTCTCCTTCCCATCTTAGTACCATTGTAGTTATAAACATCTGCATTTTTTAGAAGCATTTTACCCATTTATTTTTTTAAACATTCAAGAACTGCTGACGTACTGTGGATGTAGAGTATAAAACTTGAAAAATGCAGATGTTGAAGGAATAATAGGTATCTTGTGCTTTAATACTTTATGGCAGGATTGTACTATAAGCAAATGAATTAAACAGCTATGTAAATCATAAAGAAAAACTAAAAATGAACCAAAGTGAAAGGATAACTTCCAGGCAGTATCTTTCTATTGTAACCTGTTATTTAAGGAAATACTAGTGATTTCTTCTAAATAGGATGTAAAACTTCTTTCAAATTACTCTTCCTCAGTCCTGCCTGCCAAGAACTCAAGTGTAACTGTGATAAAATAACCTTTCCCAGGTATATTGGCAGGTATGTGTGTAATCTCAGAATACACAGGTGACATAGATATGATATGACAACTGGTAATGGTGGATTCATTTACATTGTTTACACTTCTATGACCAGGCCTTAAGGGAAGGTCAGTTTTTTAAAAAACCAAGTAGTGTCTTCCTACCTATCTCCAGATACATGTCAAAAAAAGAAAGGTGTTTGTGCTTCCGTTTTGTTTCTGCTCAGTAATATAGTCAAGCAAGTTTGTTCCAGGTGACCCATTGAGCTGTGTATGCATTTTTGTTTATTTCAATAAAATATATTTGTATTATTTGTCCTTCATACTATCCATCCATACCACACTATCTTCTGTATCAGGTAGTCTAATAGAAATATACCTGTTTTGTTCTAAAA

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