Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DDX18P7
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:161048330-161050274  UCSC
Coordinates (T2T) chr2:161506278-161508220  UCSC
Coordinates (hg19) chr2:161904841-161906785  UCSC
Strand -
Parental Sequence NM_006773.4
Parental seq. overlap 1649 bp
Parental seq. overlap (%) 43.5%
Genomic Region Intergenic
Retrocopy Summary DDX18P7, located on chr2:161048330-161050274, is a retrocopy of the parental gene DDX18. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DDX18
Full Name DEAD-box helicase 18
Also known as Has1|MrDb
Coordinate chr2:117814691-117832377
Strand +
Gene summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DDX18P1
Bonobo Pan paniscus DDX18P1
Gorilla Gorilla gorilla DDX18P1
Orangutan Pongo abelii DDX18P1
Gibbon Nomascus leucogenys DDX18P7
Marmoset Callithrix jacchus DDX18P5
Mouse lemur Microcebus murinus DDX18P2
Rabbit Oryctolagus cuniculus DDX18P2
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DDX18P7
TAACCAGTGCAGAAGCAGCAATTCAGTCTCTAGATTCGAAATCAAAAAAGAAAAGAAGAACAAGAGAAAAATAGTGACTAATGCTGGGCGTGATACAAAAAAAGCAAAAACTGAAAACAAAGGGGAATCCGAAGAAGATGGTATCGAGGCTCCTGAAGAAACAGAAAACTGGGGGGAAGCCAGACAATGAGAGAGATGAGAATACTTCATTTCTTCTCTAATTTTGTCAGTGAAAACACTTTGAAGGCAATAAAAGAAATGGGCTTTACCAACATGACTGAAATTTAGCATAAAAATGATGGGCCACTTATGGAAGGCAGGATCTTCCAGCAGCTACACAAACCAGCAGTGGCAAAAACCCTGGCATTTCTCATCCCTGCATTTGAACTAATTGTTAAGTTAAAATTCATGTCCAGAAATGGAACAGGAGTCTTTATTCTCTCACTAATTAAACAGCTTGTCCTGAGACTCTTGGTGTTCTTAAGGAGCTAATGACTCACCATATGCACATGCATGGGTTGATAATGGGTGGCAGTAACAGATCTGCTGAAGTACAGAAGCTTGCAAATGGGATCAGCACTGGTGGTCACACCAGGCCATCTCCTGGGCTGTATGCAGAATTCTGCAGGATTTAAGTATAAAAACCTATGGCGTCTGGTTATGGATGAGGCTAATGATATCTTGGATGCTGGGTTTGAAGAGAAATTAAAGCAAATTATTAAACTTCTTTGAACATGGAGACTATGCCCTTTTCCGCCACACAAACTCAAAAACTTGAAGACCTGGCAAGGATTTCTCCAAAAAAAAAAAAAAAGGAACAAATGTATGCTGGTGTTGATAATGATAAAGCTACTGCAACAGTGGATAGTCTCAAGCGGGGATATGTTGTTCGTCCCTCTGAAAAAGGATTCCTTTTGCTCTTTATATTCCTTAAGAACTGAAAGAAGAAACTGATGGTCTTCTTTTCATCCTGTAGGTCCATAAAATACCACTATGAGTTGCGGAACTACATTGACTTGCCTACCTCAGCCATTCATTTCCAGAAGCAAAATTACGTGTAGAATTACATTTTTTCCAGTTCTGTAATGCAGATTCAGGGATATTGTGTACAGATGAGGCAGGGAGAGAGCTAGATATTCCTGGCTGGATTGTTCAGTATTATCCTCCAGATGACCCTAAGGAATATGTTCATCGTCGGGGGACAATAGCCAGGGACCTAAACGAAAGAGGGCATGCCTTGCTCAGTTTTTGCCCAGAAGAATTGGGTTTTGTTTGTTACCTGAAGCAACCCAAGGTTCCATTAAGTGAATTTGACTTTTCCTGGCCTAAAATTTCTGACATTCAGTCTTGGTTTGTAAAATTAATGAAAAAGAACTACTTTCTTCATAAGTCAGCCCAGGAAGCATATAAGTCATACATACGAGTAAATGATTCTCATTCTCTGAGACAGATTTTTAATGTTAATAACTTAAATTTGCCTCAAGTTGCTCTGTCATTCGGTTTCAAGGTGCCTCCTTCTGTTGATGTGAATGTGAACAGCAATGAAGGCAAGCATAAAAAGAGAGGAGGCGAGAGTAGATTCAGCTACCAGAAAACCAAGAAAGTTAAGTCCATAATCTTTAAAAACATTAGCACGAAATCATCTGATAGCAGGCAGTTCTGTCACTGAAGATACACCTTTCTTTCATCTTGAATAAGTGTCCTGAGGTGGAGTTTTTCCCCTTTGCTCTAACAAAGGCATTTTTGTAGGCTTTAGAATTTGAATGGATATAACAACAGTGTAGACTGACTTGGGTTGCGAGCACTGAGCATTGTTATTTCCAGCAAGTCTCTTTTGTATTTTTGGGATTTAAAACAGATTTTAACTGTTCTTGGTTGCTCAAGGGCAAAGCAAGGAGTCTTCTTCATCTTTCTTGTGATGAGATGATATTTTAATTTTAAATAC
>NM_006773.4
ACGTGCGGCCGGAAGGGAAGTAACGTCAGCCTGAGAACTGAGTAGCTGTACTGTGTGGCGCCTTATTCTAGGCACTTGTTGGGCAGAATGTCACACCTGCCGATGAAACTCCTGCGTAAGAAGATCGAGAAGCGGAACCTCAAATTGCGGCAGCGGAACCTAAAGTTTCAGGGGGCCTCAAATCTGACCCTATCGGAAACTCAAAATGGAGATGTATCTGAAGAAACAATGGGAAGTAGAAAGGTTAAAAAATCAAAACAAAAGCCCATGAATGTGGGCTTATCAGAAACTCAAAATGGAGGCATGTCTCAAGAAGCAGTGGGAAATATAAAAGTTACAAAGTCTCCCCAGAAATCCACTGTATTAACCAATGGAGAAGCAGCAATGCAGTCTTCCAATTCAGAATCaaaaaagaaaaagaagaaaaagagaaaaaTGGTGAATGATGCTGAGCCTGATACGAAAAAAGCAAAAACTGAAAACAAAGGGAAATCTGAAGAAGAAAGTGCCGAGACTACTAAAGAAACAGAAAATAATGTGGAGAAGCCAGATAATGATGAAGATGAGAGTGAGGTGCCCAGTCTGCCCCTGGGACTGACAGGAGCTTTTGAGGATACTTCGTTTGCTTCTCTATGTAATCTTGTCAATGAAAACACTCTGAAGGCAATAAAAGAAATGGGTTTTACAAACATGACTGAAATTCAGCATAAAAGTATCAGACCACTTCTGGAAGGCAGGGATCTTCTAGCAGCTGCAAAAACAGGCAGTGGTAAAACCCTGGCTTTTCTCATCCCTGCAGTTGAACTCATTGTTAAGTTAAGGTTCATGCCCAGGAATGGAACAGGAGTCCTTATTCTCTCACCTACTAGAGAACTAGCCATGCAAACCTTTGGTGTTCTTAAGGAGCTGATGACTCACCACGTGCATACCTATGGCTTGATAATGGGTGGCAGTAACAGATCTGCTGAAGCACAGAAACTTGGTAATGGGATCAACATCATTGTGGCCACACCAGGCCGTCTGCTGGACCATATGCAGAATACCCCAGGATTTATGTATAAAAACCTGCAGTGTCTGGTTATTGATGAAGCTGATCGTATCTTGGATGTGGGGTTTGAAGAGGAATTAAAGCAAATTATTAAACTTTTGCCAACACGTAGACAGACTATGCTCTTTTCTGCCACCCAAACTCGAAAAGTTGAAGACCTGGCAAGGATTTCTCTGAAAAAGGAGCCATTGTATGTTGGCGTTGATGATGATAAAGCGAATGCAACAGTGGATGGTCTTGAACAGGGATATGTTGTTTGTCCTTCTGAAAAGAGATTCCTTCTGCTCTTTACATTCCTTAAGAAGAACCGAAAGAAGAAGCTTATGGTCTTCTTTTCATCTTGTATGTCTGTGAAATACCACTATGAGTTGCTGAACTACATTGATTTGCCCGTCTTGGCCATTCATGGAAAGCAAAAGCAAAATAAGCGTACAACCACATTCTTCCAGTTCTGCAATGCAGATTCGGGAACACTATTGTGTACGGATGTGGCAGCGAGAGGACTAGACATTCCTGAAGTCGACTGGATTGTTCAGTATGACCCTCCGGATGACCCTAAGGAATATATTCATCGTGTGGGTAGAACAGCCAGAGGCCTAAATGGGAGAGGGCATGCCTTGCTCATTTTGCGCCCAGAAGAATTGGGTTTTCTTCGCTACTTGAAACAATCCAAGGTTCCATTAAGTGAATTTGACTTTTCCTGGTCTAAAATTTCTGACATTCAGTCTCAGCTTGAGAAATTGATTGAAAAGAATTACTTTCTTCATAAGTCAGCCCAGGAAGCATATAAGTCATACATACGAGCCTATGATTCCCATTCTCTGAAACAGATCTTTAATGTTAATAACCTAAATTTGCCTCAGGTTGCTCTGTCATTTGGTTTCAAGGTGCCTCCCTTCGTTGATCTGAACGTCAACAGTAATGAAGGCAAGCAGAAAAAGCGAGGAGGTGGTGGTGGATTTGGCTACCAGAAAACCAAGAAAGTTGAGAAATCCAAAATCTTTAAACACATTAGCAAGAAATCATCTGACAGCAGGCAGTTCTCTCACTGAACACATGCCTTCCTTTCATCTTGAATAACTTTGTCCTAAAATGAATTTTTTTTCCCCTTGATTTAACAGGATTTTTGTAGACTTTAGAATTTGGACTTACCTAACAAGAGTATAAATTGACTTGGGTTGCAAGCACTGAGCACTGTTACTTCTATCACGTCTCTCTTTTATTTCTGGGATATAAAACAGGCTTTAAGTTTCTTGGTTGCCCAAGGGCAGAGCAAGGAATATCTGGTGTTTCTTGTGATGATAATATTTTAATTTTAAATATCCCTCCCTCATACAAGTGTATGTTACCATTTTAATATAATTCTTTTTGTACCTTTCCTTCTTGTTTTGCGAAGATTTTTGTGGCATGGATTGCTGTGCTCACTGCTGTAAAAGGTGACCTAGTGTACTGGGCAGCTGGTGGCGGTGCAGAAAAGAGTCTCAGGTTATTTTTTGTTTTTAGTTATTTCTTGGACCTTGACAGTATCTAATGACTCCTCCTGAAAATGCTGCAGTATAAAAGAGCAAAGAGCTTTGGGAAATACCTAAGAAGCACCTTAAGATTAGGGTGGCATTGCTTTTATAGATTCTTGATTTTAAAGCAACAGGCCTTTCTCAGGTGTTGCATTTTTTGGAGCAAAAACTATGGGTTGTAATTTGAATAAAGTGTCACTAAGCAGTTATAACGTTTGATGGCTGGGGGGTAGGAAGAGGATGGAATTGAGATGTTTGAGCCTCATTTACATCAATAGAGGTGTAATGTACTGCATTTCTTCATTTGGTAACATAACAAAGACTTTCATACAAAGAACGATGATGCTCCTCATTAAGATTTGTTTAATTCAAGGTGGTTTGGATTTGGTAAGCCTTTGCACTCTGTAGAGTACTTAGAAGACAAGGGCAACTTACTTGGAGTTAGAGCCAAGCTGTCAGACGGTGCCCAGCACACATTAATGTTAGCTTCTTTCTGAGAAAAAAATACCTCTTCCAGGCCCTGAAACAAAAAATACATTTGCTGTGAAGATTGAAAATGAACAAAGTTAGAAAAAAAAACAGCAAAATCAGTGATTTAGTCAGATGAGTTTTTCGTTGTAGGAGCACTTGATTTCTAGTGTGTTTTGTACAGTATATAACTACAAGATAGTACATTTTGTAGCAGTTCAAAGCCAAAGTTGCTAGCATCATTTTGCTGTTGTGCCAGTTAATCATAGGATCCCATTAAATAAGTGTGCTAACATCGAATATAGAGAAAACTGGTAAAGAACATTCCAGTAGGAAAAGAAAAGAACAATCTTCCATTTCTGGGCTTGGCCACCATCACCCTGGTCGGACCTGTCCTGGACTTCCAACCTTGACTGCTGAGCTCCTGGCTTAGCTTCTTGGGTTCCTAATTCCTGGTGTTTAATAATTCTCTCCACGATCATGTTTTTCTGATTTTTTTTTTCAGAAATAATGTTTTTTAAAAGACAAAAACAAAGGGAAGAATATTTAATTACTGAGcagaagtaaatactgttggcattttgtacataatctaatttttatatgcatgttcatgctttttaatttttttatcaaaaattaagtcatctacctactacttgtaaccagcttgtttcataacatgttattttcctgtgtcattaaataattacttcaatgttg

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