Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CYRIBP1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:169658248-169658843  UCSC
Coordinates (T2T) chr2:170135404-170135999  UCSC
Coordinates (hg19) chr2:170514758-170515353  UCSC
Strand -
Parental Sequence NM_001353245.1
Parental seq. overlap 526 bp
Parental seq. overlap (%) 13.7%
Genomic Region Intragenic (CFAP210)
Retrocopy Summary CYRIBP1, located on chr2:169658248-169658843, is a retrocopy of the parental gene CYRIB. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CYRIB
Full Name CYFIP related Rac1 interactor B
Also known as BM-009|CYRI|CYRI-B|FAM49B|L1
Coordinate chr8:129839593-130017129
Strand -
Gene summary Enables small GTPase binding activity. Involved in several processes, including cellular response to molecule of bacterial origin; negative regulation of small GTPase mediated signal transduction; and regulation of organelle organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FAM49BP1
Bonobo Pan paniscus CYRIBP1
Gorilla Gorilla gorilla FAM49BP1
Orangutan Pongo abelii FAM49BP1
Gibbon Nomascus leucogenys FAM49BP1
Green monkey Chlorocebus sabaeus FAM49BP1
Crab-eating macaque Macaca fascicularis FAM49BP1
Rhesus Macaca mulatta FAM49BP1
Baboon Papio anubis FAM49BP1
Golden snub-nosed monkey Rhinopithecus roxellana FAM49BP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CYRIBP1
TGTATCAGAGTTCTTAAGGACCAACCTCCTAATAGTGTAAAATATCTTCTAAATGCTCTCCGGTACACAATAAAACATTTGAATGATCAGACTAACTCCAAGCAAATTAAATCCATGATGCAATAACAGTTCGGGAATAAGCACCTGTTGTAGACAGAAGACAGTATTCTGCACTGACTGAGAATACAGTTTTTTAGTGATTGCAATTACCATGACATTTTTCTTGCTTTTATGTCTTCCTCTGTTCCTCTTCTCTCCTTTAAGATCATGTTCTTATTCCTAAGACTTCTTCTCTATACCCAAATTAGTAAAGTTATACTCTAAAGAGATATTGTCCTTTCAAACAGGTAACCTACAGCAGCTAATTATTGGGGTCTCTACTGAGAAAAATTCTGTGACTTTTATCTAAATATTTTCAAATGTGAATTTTGGGGAAACTAATATTTATTTGCTTCTCCTACATGGCAAAACTGCCAATTCTGCTATTTGAAAACCCCCAATGACTTTATTTTCTACTATCACTTTTTTCATGTGCTGCCACAAAATGAAAATGTTTAAATATGTTGTACAAATGGTAGCCAACACAAACTTTTTTG
>NM_001353245.1
aggcccagtaagtatctgcgggagggctgaatGGGTGCGTGGACAGCATTCCTCTCACTGACCCCGCTGCGAGGTGAGCCAGGCAGGGGCTGTCACCATTCCTGAAGTCCAGgagaagaaactgaggcctggaatttgattaactcattcaaggttacccagttggtaattcatttgcacacctgttagcaagaaacagaagttgaaggactggaacaagtgaactaggaaagagggaacgccaatccaaggATAGAAGGACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCTTAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGCCAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTACAGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAGAAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGCTGGCCACGAAATACGAGAGGCAATCCAGCATCCAGCAGATGAGAAGTTGCAAGAGAAGGCATGGGGTGCAGTTGTTCCACTAGTAGGCAAATTAAAGAAATTTTACGAATTTTCTCAGAGGTTAGAAGCAGCATTAAGAGGTCTTCTGGGAGCCTTAACAAGTACCCCATATTCTCCCACCCAGCATCTAGAGCGAGAGCAGGCTCTTGCTAAACAGTTTGCAGAAATTCTTCATTTCACACTCCGGTTTGATGAACTCAAGATGACAAATCCTGCCATACAGAATGATTTCAGCTATTATAGAAGAACATTGAGTCGTATGAGGATTAACAATGTACCGGCAGAAGGAGAAAATGAAGTAAATAATGAATTGGCAAATCGAATGTCTTTGTTTTATGCTGAGGCAACTCCAATGCTGAAAACCTTGAGTGATGCCACAACAAAATTTGTATCAGAGAATAAAAATTTACCAATAGAAAATACCACAGATTGTTTAAGCACAATGGCTAGTGTATGCAGAGTCATGCTGGAAACACCGGAATACAGAAGCAGATTTACAAATGAAGAGACAGTGTCATTCTGCTTGAGGGTAATGGTGGGTGTCATAATACTCTATGACCACGTACATCCAGTGGGAGCATTTGCTAAAACTTCCAAAATTGATATGAAAGGTTGTATCAAAGTTCTTAAGGACCAACCTCCTAATAGTGTGGAAGGTCTTCTAAATGCTCTCAGGTACACAACAAAACATTTGAATGATGAGACTACCTCCAAGCAAATTAAATCCATGCTGCAATAACAATTCTGGAATAAGCACCTGCTGTAGACAGAAGACAGTATTCTGCAATGACTGAGAATGCAGTTTTTTAGTGATTGCAATTACTATCTCATTTATTCTTGCTTTTATTTCTTTCCTCTGTTCCTCTTCCCTCTTTTTTAATCATGTTCTTAAGACTTCTTTTCTGTGCCAAAATCAGTAAAGTTACACTCTGAAGGGATATCATCCTTTCAAACGGGCCATCTAAGGCAGCTAATTATGCATTGCATTGGGGTCTCTACTGAGAAAAATTCTGTGACTTGAACTAAATATTTTTAAATGTGGATTTTTTTTGAAACTAATATTTAATATTGCTTCTCCTGCATGGCAAAACTGCCTATTCTGCTATTTAAAAACCCTCAATGACTTTATTTTCTACTGCCGCCTTTTTCATGTGCAACCAAAATGAAAATGTTTAAATTAACTGTGTTGTACAAATGGTACCCAACACAAACTTTTTTTAAATTAGTAATACTTTTGTTTAAAGTTTTAAGTTTGCATTTTGACTTTTTTTGTAAGGATGTATGTTGTGTGTTTAACCTTTATTAACTAACGTTAAAAGCTGTGATGTGTGCGTAGAATATTACGTATGCATGTTCATGTCTAAAGAATGGCTGTTGATGATAAAATAAAAATCAGCTTTCATTTTTCTAAGTGTGGCTTGGTTTACTGATGTTTTGTTTTTAGGCTTCTGAAGTTTTCCCCATGTATGTTTTTATGGAATGCATATATACATTACATGATTTTTTCTTCTTTTAGGGGAGAGCCGGGTCTTTTCATTAGAATTTTGATCATTGTCTATGTATATACTTTTAATTGCCTTTAAAATTTTGCTAAGTATATTAAGACCAGTGATCTTTTCATTAACTGGACTTTTATTCTTGATTTACTCTTGTATGGATGTAGTAATGGAAGGAAAACCGCATCCTTGCTTGATTCTCCATTTCCAGGGGAGCGGGTAGCAACATGAAGGCAGAGTAGCCCTTTAATCATGGGAAGAGAGTGATTATAAGAGGGACTTCCCAGGAGAAAAGCAGAGGCCATGATCTCACTAGTGGTAGAAAACTAACAGGTTTCAGTTTAAGATCATAAAACCTAAATCATGAAATCTAaatctcatggttggaacaaactacttaaaggttgtctagttcaaccATGCCAGTGTTTTAAATATTTAGGAATATCCGAGGTATAATACAATTAAAATGTTTAACCATGGAAGAGAATCACAGAGGCTTCCATCAGACCCTTCTGGATTAATAGGGCCAGATCATGGCACACACAGCTTCTcaagatcacatccctgctgatctctctggccctcctgatcactgctcccccacttcacaccctgtcctgcagccaggccctactgcttgctgttcacaaattgttccatgtgatgtcacttccttagctctggtctggctggtccctgaacctgacattcccttcctccccttgtgaccctctaatgaacgccaactttcatctttgaagggttagcttctattacctccttcatgaagccttcTGGATAACATTGGCCATATCCTTCTAGGCATCTTCTAAGAATAGtgtaataggctgaatagtggcccccaggagatacattcactgggaatctccacgtgtgacattatttggaaaaagtttttgcagatgaaatcaaggacctggaaatgagatcaacctgtagtagggtgggccctaaattcaatgactagctcttagaaaagaaggggaaatagacacacagagctgaaggccatgggaagatggaggcagagattagagcaatgcatctatgagccaaagaaccctaagaattggaggaagtcactagaagctaggaaaacaggcatgtcacagattctccctcagagtctcgagaaggaaccaaccctaccaatatcttgatttcagacatctggcctccaggattgtgagggaataaatttctgttgttttaagccatgcagtttgtggtattttggtacagcagccttaagaatctgatacaTGTATCTCGTAAAACACCTCTGATACTTACCTGCGCTTGTGGCTGTGTTTTCTGATACTATGAGAGCCGTAGTATCTGGATACCGGAGAGTctgcgaacttgagagaagggccgtgtctgattttccttcagtgtcccaaggaaggatcttgcacagtacccagatttggagaggtgccaagtgaatgcttcggtggactgaatgaatACAAATCAAAAATAATGATGCAGCGGGAATGGATGCAGTAAGATTGCTGTGGCCTATGCAGTTCACACAGTTCACACTCTGCATGTTGAGGAGTAAGTGGACAGATCTCTTAAGCCcaggggctagcaaaccggtctgtgggccaatttactcaccgtctgtttttgtacagcttgtgagctaaaaatggtttttaaaaaggttgaatacaatcaaaagaataatattttgtggcatgagaaaagcatatgaaattcaaattttagtgttcataaataaaattttattggaacctaa

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