Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RNF11P1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:189928360-189931014  UCSC
Coordinates (T2T) chr2:190417728-190420379  UCSC
Coordinates (hg19) chr2:190793086-190795740  UCSC
Strand -
Parental Sequence NM_014372.5
Parental seq. overlap 1997 bp
Parental seq. overlap (%) 61.2%
Genomic Region Intragenic (C2orf88)
Retrocopy Summary RNF11P1, located on chr2:189928360-189931014, is a retrocopy of the parental gene RNF11. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RNF11
Full Name ring finger protein 11
Also known as CGI-123|SID1669
Coordinate chr1:51236273-51273447
Strand +
Gene summary The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN). [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RNF11P1
Bonobo Pan paniscus RNF11P1
Gorilla Gorilla gorilla RNF11P1
Orangutan Pongo abelii RNF11P1
Gibbon Nomascus leucogenys RNF11P3
Marmoset Callithrix jacchus RNF11P3
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RNF11P1
CCAATTCAATTTCTACCGTGCATGTACATCTACCACCTGGACTGTATTATGACTGGTAGATGAGATCCTTCACGTGCCCCTCCTCCATGGAGCCAGTTGATGCAGCACTGCTTTCAACCTAGACTATTGAGCCAGGGTGTCTCATCTGACTTCAAGTGAACCATCATGTTGGGGGGTTTTGATCTGTTGTCACTAAGCCCAAAGAACCAGGGATTAGGAATTAAGATCATGCACAAAAGTTTCCTAAAAATTCCTGGATGGCTGCAGATGTTGGGGGAAAGTACATGATATTTCAAAACTTAGAGAGAAAAGTAGGATGGTATTTTTATGTAAGGCCTTGACCCAATGTTCAAAAATATAACTGTATTTAGACCTTGTTATTGCTCCAGTACATAGGAATTGTGTAAAGTGTTACAGCAGCTGTATTTGTTTAAATTGTATGTACTGAAGATAAGCAAAAGATAGTAGTTATTTTCCTAAATGAAATAACTTTCTTCTCTTCCCCCTCCCCATCCCCAAATTCTTTTCTGATGTTACTGGCATTTGGGTCAAGGTTTTATTAAAAGCTGCATTTTATAACACTGGCACACACAAAAAAAGTAGTTTAAAGCTTGTTTGCACAGTTATTTTTTTCCATTAGAAATGGAATTCATTGCCTTAGGTCCTTTTAAATAGTGTATTATTATCATTGGGCTAGTTCTATGCTTGAAAACCAGTTTATTTATAATCTGTTATAAGTGCTATATTCTGTTTGCAGTCAGGAAATGCAGAATTCAAAGTGATATCCTAGCTTGTAAGCAAACTGAGATGTACTATCCCTTTTCTATTAAAAAAAAAAAGTGTCAATAAACCAACTCTATTACAGTGGGGTTTAATATTACACTTTCCTGTGTGTTTTATCTAATTATTTTGGTTGTTAATATGGTGATAATTGAAAATCAAGGTAAATTTTAAATATTAAGAATTCTGATTTATTGAGATTGAATTATGCCACCATGTTTATGAAAAATGAAGGTGGCACCACGGTGAGACCTCATGAGAAATAGTTACTCAGCTGTAACAATTTTGATTTATTCTGTTTCCTGTGACCTCCTTCCCTCTTGTCTTGAACCATAGCAAAAAGATACTGCATCCCTCATTACTGTAATGCTGAGGTTACTGAAGTTACATAAAACACATCTCAGTCCCTGTTTCTTGGAAAGGTATCTATTAAGTCCTGCTAGCTAACTGACAAAATGAAGCAAGTAGAAGCAAAAAGTGTGTTTCACATTTTGCACACAAATGCAGAATTTGTATAACCACATGACTTCATAGTTGTGATCTCAAAAAAGAAGGAATTTCTCCATTTTTTCTTCCATTTAATGTAAGAATACTTTAAATCTCTAGGCTTCTGAAGTGTTAGAGGTAAAGACATAGTAGTAATGTTTTATCCATTTAATGTATTTATTTTTTCGTATATACTCCTAGGTGACCTACTTTTTCACTTCAGTGACATAACAGTAAAGAAAAATCATTCATTAGGAAAAGGAAAAGTGGTCTCAACCTAACAAAGAAATCAGAAATGTTTCTTATTATTTTATGTTGAGCTGCATATTGGACTCTAACATTTTTCTACATGCAAAACACAGTGTCATGAAGCTTCTTCATAATTGCAATATAGAGGAATTTAGTATCTCTTAAGTACTTTGTAAAGATTTGACATTCAACTATAGTATCCATATGTTGGTTAAATTTCCTTATGAGCCCCATGATGGAAAGACTTAAAGATGAATTTGAGAAAAATTGAAAGAAATTAGAGTATCAAGTTGTGTTAAATTGTTACATGTATCTTGCTTAAATTTCTGTTTATTAATTTATATCCACCCAATTACATAAAGCAAATTTGAAGGAAACAACTGAAGTTGTGAAATATTATCTGTGATAATTGCTTTTTTTATTCTTGTGTTTTCTACTTAAACATGATGTCTATGTCATCAAGTATTATAGTCAGACTTTTTTCTCAATTGTTAAAATTGGTAAATGAACTTTTTTAAAATGAAGATGGGGAACTGCCTCAAATCCCCCACCTCGGATGACATCTCCCTGCTTCAGGAGTCTCAGTCCGACTGGGCTAGCTTTAGCGAGGGAACTAAGCCGTATCAGGAGCCGCTGCCATATCAGGAACAGGTTCCAGCTCCAGTCTACCATCCAACACCTAGCAAACACCTATCCTAACAAATTAGGATAGCTCAAAGAATAGGCCTTATACAACATCTGCCTAAAGGAGTTTATGACCCTGGAAGAGATGGATCAGTAAAACAGATCTGGGAGTGTGTGATCTGTATGATGGACTTTGTTTATGGGGACCCAATTCAAt
>NM_014372.5
AGTGCCCGAGCCGGCCTCGTTCTGGCTGCCGCCGTCTCGCTGAGGCGGAGTAGGATGAGGCCCGCGGCCGTGGCTCCGGCGTCGGCGGGGgcagcagcagctgaggcagcagctgaggcagccgcGACGGCCGCGCCCCCCCCCGCTGACCTGGATTAGGCCCAGCAGCTCCGTGGCCGCCGCCGCCCCGCGGGGGGGCGGGGTGGGGAAGTGCTTCGTCTCCCCGCCCCCCCCCCCCCATCGCTGCCTCGCAGGAGGCGAACGCCGCGACCCCAGCGGAGCCCGCGGCCCAGCCTTGATCCCCCAACCCCGGGGGCTGGCATGAGCGGCCCCTCGGCGGCACCGTGGGGCGGTGGAGTCGCCTCCGCCTGATCCCCGGCCTGTCGCCCGACCCCACCTCGCCAACCGAGGCGGACCGCGGAGTGTGCGAACGACCCCACCGCTGCTTTCTCCTCCCCCAGATCACGCACCCCAGCTCCGGAAGATGGGGAACTGCCTCAAATCCCCCACCTCGGATGACATCTCCCTGCTTCACGAGTCTCAGTCCGACCGGGCTAGCTTTGGCGAGGGGACGGAGCCGGATCAGGAGCCGCCGCCGCCATATCAGGAACAAGTTCCAGTTCCAGTCTACCACCCAACACCTAGCCAGACTCGGCTAGCAACTCAGCTGACTGAAGAGGAACAAATTAGGATAGCTCAAAGAATAGGTCTTATACAACATCTGCCTAAAGGAGTTTATGACCCTGGAAGAGATGGATCAGAAAAAAAGATCCGGGAGTGTGTGATCTGTATGATGGACTTTGTTTATGGGGACCCAATTCGATTTCTGCCGTGCATGCACATCTATCACCTGGACTGTATAGATGACTGGTTGATGAGATCCTTCACGTGCCCCTCCTGCATGGAGCCAGTTGATGCAGCACTGCTTTCATCCTATGAGACTAATTGAGCCAGGGTCTCTTATCTGACTTCAAGTGAACCACCATTTTGGTGGTTTTGATCTTTTGTCACTGAGCCCAAAGAGCCAGGGATTAGGAATTAAGATCGTGCACAAAAGTTTCCTTAAAATTCCTGGATGGCTGCAGATGTTGGGGGAAAAAGTACGTGATATTTTAGAAACTTAGTGGGAAAAGTAGGATGGTATTTTTATGTAAAGCCTTGACCCAATGTTTAAAAATATAATTGTATTTAGATCTTGTTATTGCTCCAGTACATAGGAATTGTGTAAAGTGTTAACAGCAGCTGTATTTGTTTAAATTGTGTGTATTGAAGATTAGGAAAAAGATAGTAGTTATTTTTCCTAAATGAAATAACTTTCTTCTCTTCCCCTTCCCCACCCGAATTCTTTTCTGAAGTTGCTGGCATTTGGGTCAAGGTTTTATTAAAAGCTACATTTTATAACACTGGCACACACAAAAAAGTAGTTTTAAGCTTGTTTGCACAGTTCTTTTTTTCCATTGGAAATGGAATTCATTGCCTTAGGTCTTTTTAAATAGTGTATTATTATCGTTGGGGCTGGCTCTATGCTTGAAAACCAGTTTATTTATAACCTGTTATAAGTGCTATATTCTGTTTGCAGTTAGGAAATGCAGAATTCAAAGTGATCTCCTAGCTTGTAAGCAAACTGAGATGCACTATCCCTTTTCTATAAAAAATAAGTTAATGTGTCAAGAAACCAACTCTATTAAGGTGGGGTTTAATATTACCCTTTCCTATGTGTTTTATCTAATTATTTTGGTTGTTAATATGGTGATAATGGAAAGTCAAGTTAAATTTTAAATATTAAGAATTCTGATTTATTGAGATTGAATTATGCCACCACGTTTATGTAAAAATGAAGGTGGCACCGTGGTGAGACCTAATGAGAAATAGTTACTCAGTTGTAAAAATTTTGATTTATTCTCTTTCTTCTGACCTCCTTGCCTCTTGTCTTGAACCATAGCAAAAGGATACTGCATCTCTCATTACTGTAGTGCTGAGGTTATTGAAGTTATACAAAACACATCTCAGTCTCTGTTTCTTGGAAAGGTATCTATTACATCCTGCTAGCTGACTGACAAAACTAAGCAGGGAGAATAAAGATAATTGTATTTTATGTTTTGCACACAAACGCAGAATTTGTATAACCATATGACTTCATAGTTGTGATCTCAAAAAAGAAGGAATTTCTCCTTTGTTTCTTGCAGTTAATGTAAGAATACTTTAAATCTCTAAGCTTCTGAAGTGTTAGAGGTAGAGATGGTCTAGTAAAGATGTAGTAGTAATGTTTTATCCATTTAGCATGTGTTTATTTTTTCATATGTACTCAAAGGTGACTTATTGGTTCACCTCAGTGATATTACAGCTAAAAAAATCATTCATTAGCAAAAGGAAAAGTGGTCTCAACCTAACATCAGAAGTGTTTCTTATTATTATTTTATATTGAGTTGAATATTGAACTCTAACAGTTTTCTACATACAAAACACAGTGTCATGAAGGTTATTCATAATTGCATTATAGAGGAATGTAGTATGTCATAAGTACTTTGTAAAGATTTGACATTCAACTGTAGTATCCATATGTTGCTTAAATTTCCTTATGAGCCCCATGATGGAAAGACTTAAAGATGAATTTGAGAAAAATTGAAAGAAATTAGATTATCAGGTTCTGTTAAATTGTTACATGTATCTTGCTTAAATTTCTGTTTATTAATTTATATCCACCCAAGTACATAAAGCAAATTTGGAGGAAACAACTGAAGTTGTGCAATATTTTCTGATAATTGCTTTTTTTATTCTTGTGTTTTCTACTTAAACATAATGTCTGTGTCATCAAGTATTATAGTCAGACTTTTCTTTTTTTCTAGATTGTTAAAATTGGCAAATGAACTTTTTTAAAAATCATCTTCCATGTTGCAGTTAGTCTTTCTTTTCATTACAAGTCTTTCACAGAAGTTTGGTGGTAATATTGAAAGAACTAGCATTGGGCAGAATGTGTCTTTTTTAGGCACTTTATATTCTCAACATACAATGTTAAGAACCATCAATTTTGACTTTTACTAAGTTGTTAAATAAAGTTATAATACAGCTGTGAA

Publications

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