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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ATP5POP1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr21). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:206236165-206236862  UCSC
Coordinates (T2T) chr2:206718069-206718766  UCSC
Coordinates (hg19) chr2:207100889-207101586  UCSC
Strand -
Parental Sequence NM_001697.3
Parental seq. overlap 648 bp
Parental seq. overlap (%) 85.7%
Genomic Region Intergenic
Retrocopy Summary ATP5POP1, located on chr2:206236165-206236862, is a retrocopy of the parental gene ATP5PO. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ATP5PO
Full Name ATP synthase peripheral stalk subunit OSCP
Also known as ATP5O|ATPO|HMC08D05|OSCP
Coordinate chr21:33903453-33915804
Strand -
Gene summary The protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ATP5POP1
Bonobo Pan paniscus ATP5POP1
Gorilla Gorilla gorilla ATP5POP1
Orangutan Pongo abelii ATP5POP1
Gibbon Nomascus leucogenys ATP5POP1
Green monkey Chlorocebus sabaeus ATP5OP2
Crab-eating macaque Macaca fascicularis ATP5OP2
Rhesus Macaca mulatta ATP5POP2
Baboon Papio anubis ATP5POP3
Golden snub-nosed monkey Rhinopithecus roxellana ATP5POP2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ATP5POP1
CCCCAGCAGTGTCTGGGCTCTCCTGGCAGGTGTGATGCTTCAGTACATCTGTGGTCAGACCATTGTCAAGCTTGTGAGGCCTCCTGTTTAGGTACACAGTATGGAAGGTCGCTATGCCATGGCTCTTTATTCTGCTGCATCGAAACAGAATAAGCTGGAGCAAGTAGAAAAGGAGCTGTTGAGAATAGCACAAATCCTAAAGGAACCCAAAGTGGCTGCTTCTATTTTGAATCCCTGTGTGAAGTGTTCCATTAAAGTGAAAAGCCTAAATGACATCACAGCCAAAGAGACATTCTCTCTCCAACCCTGATCAATTTGCTTGCTCAATATGGTTGCTTAAGCAATACCCAAGGAGTCGTTTCTTCTTTTTCTATCATGATGAGTGTCCACCGTGGAGAGGTACCTTGCACAGGGACCACTGCATCTCCTTTAGAGGAAGCCACACTCTCTGAATTAAAAACAGTCCTGAAGAGCTTCCTAAGTCAAAGCCAAGTATTGAAATTGGAGGGTAAGACTGATCCGTCAATCATGGGTGGAATGATTGTGCGCATTTGAGAGAAATATGTTGACATGTCTGTTAAGACCAAGATTCAGAAGCTGAGCAGGGCTATGCGGGAGGTTGTCTAAAAGTATTGGTTTTCTACCATCACTGAAAATTCTTAAACTTGGAGCAACAATAAAAAGCTTCCAGAGCAGAa
>NM_001697.3
CTCTTCCCACTCGGGTTTGACCTACAGCCGCCCGGGAGAAGATGGCTGCCCCAGCAGTGTCCGGGCTCTCCCGGCAGGTGCGATGCTTCAGTACCTCTGTGGTCAGACCATTTGCCAAGCTTGTGAGGCCTCCTGTTCAGGTATACGGTATTGAAGGTCGCTATGCCACAGCTCTTTATTCTGCTGCATCAAAACAGAATAAGCTGGAGCAAGTAGAAAAGGAGTTGTTGAGAGTAGCACAAATCCTGAAGGAACCCAAAGTGGCTGCTTCTGTTTTGAATCCCTATGTGAAGCGTTCCATTAAAGTGAAAAGCCTAAATGACATCACAGCAAAAGAGAGGTTCTCTCCCCTCACTACCAATCTGATCAATTTGCTTGCTGAAAATGGTCGATTAAGCAATACCCAAGGAGTCGTTTCTGCCTTTTCTACCATGATGAGTGTCCATCGCGGAGAGGTACCTTGCACAGTGACCTCTGCATCTCCTTTAGAAGAAGCCACACTCTCTGAATTAAAAACTGTCCTCAAGAGCTTCCTAAGTCAAGGCCAAGTATTGAAATTGGAGGCTAAGACTGATCCGTCAATCTTGGGTGGAATGATTGTGCGCATTGGCGAGAAATATGTTGACATGTCTGTCAAGACCAAGATTCAGAAGCTGGGCAGGGCTATGCGGGAGATTGTCTAAAAGTGTTGGTTTTCTGCCATCAGTGAAAATTCTTAAACTTGGAGCAACAATAAAAAGCTTCCAGAACAGATCA

Publications

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