Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SNAI1P1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:209808737-209808925  UCSC
Coordinates (hg19) chr2:210673461-210673649  UCSC
Strand +
Parental Sequence NM_005985.4
Parental seq. overlap 160 bp
Parental seq. overlap (%) 9.4%
Genomic Region Intragenic (UNC80)
Retrocopy Summary SNAI1P1, located on chr2:209808737-209808925, is a retrocopy of the parental gene SNAI1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SNAI1
Full Name snail family transcriptional repressor 1
Also known as SLUGH2|SNA|SNAH|SNAIL|SNAIL1|dJ710H13.1
Coordinate chr20:49982980-49988886
Strand +
Gene summary The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Orangutan Pongo abelii SNAI1P1
Green monkey Chlorocebus sabaeus SNAI1P1
Crab-eating macaque Macaca fascicularis SNAI1P1
Rhesus Macaca mulatta SNAI1P1
Baboon Papio anubis SNAI1P1
Golden snub-nosed monkey Rhinopithecus roxellana SNAI1P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SNAI1P1
TCGGCCTAGTGAGTGGGTCGCCTGCGCTACTTCTGCGCTACTCAGCGACCTCGTTGCCTCTGCCACCATGCCGCGCTCTTTCCTCGTCAGGAAGCTCCCTGACCCTGATCGGAAGCCCAACTACAGCAAACTGCCGGACTCGAATCCAGAGTTTACCTTCCAGCAGCAGCCCTACCACCAGGCCCACCT
>NM_005985.4
ATTGCGCCGCGGCACGGCCTAGCGAGTGGTTCTTCTGCGCTACTGCTGCGCGAATCGGCGACCCCAGTGCCTCGACCACTATGCCGCGCTCTTTCCTCGTCAGGAAGCCCTCCGACCCCAATCGGAAGCCTAACTACAGCGAGCTGCAGGACTCTAATCCAGAGTTTACCTTCCAGCAGCCCTACGACCAGGCCCACCTGCTGGCAGCCATCCCACCTCCGGAGATCCTCAACCCCACCGCCTCGCTGCCAATGCTCATCTGGGACTCTGTCCTGGCGCCCCAAGCCCAGCCAATTGCCTGGGCCTCCCTTCGGCTCCAGGAGAGTCCCAGGGTGGCAGAGCTGACCTCCCTGTCAGATGAGGACAGTGGGAAAGGCTCCCAGCCCCCCAGCCCACCCTCACCGGCTCCTTCGTCCTTCTCCTCTACTTCAGTCTCTTCCTTGGAGGCCGAGGCCTATGCTGCCTTCCCAGGCTTGGGCCAAGTGCCCAAGCAGCTGGCCCAGCTCTCTGAGGCCAAGGATCTCCAGGCTCGAAAGGCCTTCAACTGCAAATACTGCAACAAGGAATACCTCAGCCTGGGTGCCCTCAAGATGCACATCCGAAGCCACACGCTGCCCTGCGTCTGCGGAACCTGCGGGAAGGCCTTCTCTAGGCCCTGGCTGCTACAAGGCCATGTCCGGACCCACACTGGCGAGAAGCCCTTCTCCTGTCCCCACTGCAGCCGTGCCTTCGCTGACCGCTCCAACCTGCGGGCCCACCTCCAGACCCACTCAGATGTCAAGAAGTACCAGTGCCAGGCGTGTGCTCGGACCTTCTCCCGAATGTCCCTGCTCCACAAGCACCAAGAGTCCGGCTGCTCAGGATGTCCCCGCTGACCCTCGAGGCTCCCTCTTCCTCTCCATACCTGCCCCTGCCTGACAGCCTTCCCCAGCTCCAGCAGGAAGGACCCCACATCCTTCTCACTGCCATGGAATTCCCTCCTGAGTGCCCCACTTCTGGCCACATCAGCCCCACAGGACTTTGATGAAGACCATTTTCTGGTTCTGTGTCCTCTGCCTGGGCTCTGGAAGAGGCCTTCCCATGGCCATTTCTGTGGAGGGAGGGCAGCTGGCCCCCAGCCCTGGGGGATTCCTGAGCTGGCCTGTCTGCGTGGGTTTTTGTATCCAGAGCTGTTTGGATACAGCTGCTTTGAGCTACAGGACAAAGGCTGACAGACTCACTGGGAAGCTCCCACCCCACTCAGGGGACCCCACTCCCCTCACACACACCCCCCCACAAGGAACCCTCAGGCCACCCTCCACGAGGTGTGACTAACTATGCAATAATCCACCCCCAGGTGCAGCCCCAGGGCCTGCGGAGGCGGTGGCAGACTAGAGTCTGAGATGCCCCGAGCCCAGGCAGCTATTTCAGCCTCCTGTTTGGTGGGGTGGCACCTGTTTCCCGGGCAATTTAACAATGTCTGAAAAGGGACTGTGAGTAATGGCTGTCACTTGTCGGGGGCCCAAGTGGGGTGCTCTGGTCTGACCGATGTGTCTCCCAGAACTATTCTGGGGGCCCGACAGGTGGGCCTGGGAGGAAGATGTTTACATTTTTAAAGGTACACTGGTATTTATATTTCAAACATTTTGTATCAAGGAAACGTTTTGTATAGTTATATGTACAGTTTATTGATATTCAATAAAGCAGTTAATTTATATATTAAAAA

Publications

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