Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NUTF2P8
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:21362035-21364077  UCSC
Coordinates (T2T) chr2:21395483-21397525  UCSC
Coordinates (hg19) chr2:21584907-21586949  UCSC
Strand -
Parental Sequence NM_005796.3
Parental seq. overlap 506 bp
Parental seq. overlap (%) 23.4%
Genomic Region Intergenic
Retrocopy Summary NUTF2P8, located on chr2:21362035-21364077, is a retrocopy of the parental gene NUTF2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NUTF2
Full Name nuclear transport factor 2
Also known as NTF-2|NTF2|PP15
Coordinate chr16:67846933-67872567
Strand +
Gene summary This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NUTF2P2
Bonobo Pan paniscus NUTF2P2
Orangutan Pongo abelii NUTF2P2
Gibbon Nomascus leucogenys NUTF2P6
Green monkey Chlorocebus sabaeus NUTF2P3
Crab-eating macaque Macaca fascicularis NUTF2P4
Rhesus Macaca mulatta NUTF2P4
Baboon Papio anubis LOC101022919P6
Golden snub-nosed monkey Rhinopithecus roxellana NUTF2P8
Marmoset Callithrix jacchus NUTF2P12
Gorilla Gorilla gorilla Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NUTF2P8
GCATGGTTGTAGGCCAACTTAAGGCAGATGAAGACTCCATCATAGGGTTCCACCAGATGTTCCTATTAAAGAACATCAAGAAGGTGTGGGTTCGCACCAATGACATGTTCAGGCTTGCCCTGCGCAACAAGGGCTGGCCTCCTCCCAGCCAGGCACTCGTGCTGTTTCCTCCTGCTGCCTCTTCCCAGTACTATTCACACTCCTCTAGTTGCTCCAAATATCATACACAAATGAGCAGGGCAGTTGTGGGAGTGGGTACGGTGCACTGCTGCCACCGACATGTTCATGATGTTTGGTTGCTAGACAACTTGCATAGGACTGGAGAAATTTGTGTTGTACTAGCACATGCCTTAGAAAGGCTTAAGTAATGCAAAGGTTTGTCCTTTTTTTAGTGCCAGCCCCTTGAGTCTCAGTGAGGCCAGTGATGCTCCAGAATATGAGGCAAGCCAATTTGGGAGCAGATTGGACCCAGCTTCATTCAACATTACTACCAGTTATTTGATTACAATACAACCCAAGTAGGTGCAATTTACATTGACATGTCACGCCTTACATGGGAAGGACAGCTGTTCCAGGAGAAAACTAGCCTTCCCTTCTGTTCCAGAAAATCCAGCACAGCATCATGGTGCAAGGTCATCAGCCt
>NM_005796.3
GCAGACCGCGCTGGGTTGCCGCTGCCGCTGCCGCCATCGTGCCAGCCCCTCGGGTCTCCGTGAGGCCGGGTGACGCTCCAGAATGGGAGACAAGCCAATTTGGGAGCAGATTGGATCCAGCTTCATTCAACATTACTACCAGTTATTTGATAATGATAGAACCCAACTAGGCGCAATTTACATTGACGCGTCATGCCTTACGTGGGAAGGACAACAGTTCCAGGGGAAAGCTGCCATTGTGGAGAAGTTGTCTAGCCTTCCGTTCCAGAAAATTCAGCACAGCATCACCGCGCAGGACCATCAGCCCACTCCAGATAGCTGCATCATCAGCATGGTTGTGGGCCAGCTTAAGGCGGATGAAGACCCCATCATGGGGTTCCACCAGATGTTCCTATTAAAGAACATCAACGATGCTTGGGTTTGCACCAATGACATGTTCAGGCTCGCCCTGCACAACTTTGGCTGACCTCCTCTCAGCTAGGCACTCACGCTGTTTCCTCCTCCCTCCTCTTCCCAATACTATTCCCACTCCTCCAGATGCTCCAAATATCATGCACAAATGAGCAGGGCCGCGGTGGGAGTGGGCGCAGTGCGCTGCTGCCACTGAGGTGTTGTGCATGATGTTTGGATGCTAGACTAGTTGCATCTGACGGGAGAAGTTTGTGTTGTACCAGCGCATGCCTTGGAAAGACTTAAGTAATGCAAAAGGTTGTCCttttttttttttttttttttttAATCTACTGACAAGTTGCTCTAGTAACCCAAAGAAGTGAAGGAGAAAGCAGCTGCCTCACCGCCCAGACATTGATTTGTTCAGATGTTTCAATGCCTCATGATACAATAAAACCACAAAAATTTTCTTAACAGTTTAAATTGTTTTAATTAGTTTACTAGTTGGCTGGGCATCAGAAGCTACCCAGACCCGTTGTCTCTCTCATGTTTCACCCTCCCACTTCTGCCCCAACTCTGAATACCTGTTGCAGGGAGAAACTGCTGAAGCAGCACTCCCAGCTAGCCTCTCAGAAGCCGTGTAGGGCAGTTCTCTCCCACTCCACAGGGCGACTGGTCTTTGGAAAGCAGGCAGGAAGAGCTCAGGTCTGGCCTGAAGCTTCTCTCACTGAAGCCTGTGCAGTCAGTTCTGATACCTCCTGTGACTTCTGCTCTGGGTAGGTTCAGGGCCCTAGTAGCAGGAGAGATGATCCTGAATCCTGTTGAAGCTGGAGAGGCCTTGGCAAAATGGCTCATCACGTTCAGGCCCTCCGGGCTGAGTTGTCAGCAGTATCAAGGGAGGGGCCTGCTCTATCCCCAGAAGGATCAGGATCATATCCAGGATGCCCCACATACACCAAGCCAGGCAGAGGGCAGCTCAGCTCCTGTCCCATCTGCTTTGGATATCTTTACCCAAAGGCAGGTAACCCGAAGAGCCAGCCTCCACTGCCCACAGAGCCAGGCCCAGTTGTGTTGGAGTATAGGTCAGGAGCTGTGGAAGGAGGCAGTCTGTGAGGGACTCATGCTTTAGGAGTCCTCACCCCTCAGACTGCTGCAGGACATTGCCAGGCCTCTCTCCACTTCCTTCCTCAGCATACAGACTTCATGCTATCTTCCAATTCCGGGGAGTCTTAGCTATTAGGGCAGTTTCTGCTTCTCCATTTTGGGGACAAAGGCCTTGCCCAGTACAAATCTAGCCCCTTGTCCCACAGACTTCTGGATGGTATAAACCTAGTGGCAATGTAGCAACCATAGGCTAGAACCAAACCCAAGATTTGGGTCAGTGCCCTGTTAAGGGTTTTAGGATTGGTAAGGACACCACAGCTAAATCTGACATGTAAAAGGATACCCTTCCCCTGTCCCACTACGGGTGGAGGCTAAGGACCTCCTCAGATCCCACAGATTGCCTGGTGACATTGGGCACAGGGCTGGATGGTGTGCTGTTTGAGAGGACAGCATGCTCAGGAGATTTCAGTGGGAATGATCTCTAGGCTGATGTGTATTTGGGGAAGTGGGGGTGGGGAAGAGGTAGGTGCCTGCTGCCTCAAACCACCTTGTGTAAAATCTGCAATACGGCTTCTTCCATGTACCTGTGCCTGAACTGTCTGCAATAAAGAAGAATTTGTAAA

Publications

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