Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name YES1P1
Plot displaying the genomic locations of a retrocopy (in chr22) and its respective parental gene (in chr18). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr22:25647140-25650896  UCSC
Coordinates (T2T) chr22:26108289-26112045  UCSC
Coordinates (hg19) chr22:26043107-26046863  UCSC
Strand +
Parental Sequence NM_005433.4
Parental seq. overlap 2872 bp
Parental seq. overlap (%) 61.6%
Genomic Region Intragenic (GRK3)
Retrocopy Summary YES1P1, located on chr22:25647140-25650896, is a retrocopy of the parental gene YES1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name YES1
Full Name YES proto-oncogene 1, Src family tyrosine kinase
Also known as HsT441|P61-YES|Yes|c-yes
Coordinate chr18:721588-812846
Strand -
Gene summary This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes YES1P1
Bonobo Pan paniscus YES1P1
Gorilla Gorilla gorilla YES1P1
Orangutan Pongo abelii YES1P1
Gibbon Nomascus leucogenys YES1P1
Green monkey Chlorocebus sabaeus YES1P1
Crab-eating macaque Macaca fascicularis YES1P1
Rhesus Macaca mulatta YES1P1
Baboon Papio anubis YES1P1
Golden snub-nosed monkey Rhinopithecus roxellana YES1P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>YES1P1
ACGAGGAGGTGGAGGAAGGAGAGGGCCCCGGGCCTCACCTCCACCCACCGCCCCCTCCCACCACCCGGAGCTGCAGCAGCAGCGACTCATGAGAGCACAGCCAGAGGACAGATTTGATAATGGGCTGCATTAAAAGCAAAGAAAACAAAAGTCCAGCCATTAAATACCTGAAAATACTCCAGAGCCTGTCAGTACAAGGGTGAGCCATGGGAGCAGAACCCACTGCAGTGTCACCATGTCCATCATCTTCAGCAAAGGGAACAGCAGTTAATTTCAGCCGTCTTTCCATTCCATTATACCATTTGGAGGATCCTCAGGGGTAACACCTTTTGGAGGTGGGCATCTTCCTCATTCTCAGTGGTGCCAAGTTCATATCCTGCTGGCTTAACACGTGGTGTTACTATATTTGTGGCCTTATATGATTATGAAGCTAGAACTACAGAAGACCTTTCATTTAAGAAGGGTGAAAAATTTCAAATAATTAACAATACAGAAGGAGACTGGTGGGAAGCAAGATCAATCACTACAGGAAAGAATGGTTATATCCTGAGCAGTTATGTAGCGCCTGCAGATTCCATTCAGGCAGAAGAATGGTATTTTGGCAAAATGGGGAGAAAAGATGCTGAAAGATTACTTCTGAATCCTGGAAATTAATGAGGTATTTTCTTAGGAAGAGAGAGTGAAATCAAAAACGAGAGAGCGAAACTACTAAAGGTGCTTATTCCCTCTCTATTCGTGATTGGGATGAGGTAAGGGGTGACAATGTGAAACACCACAAAATTAGGAAACTTGACAATGGTAGATACTATATCACAACCAGAGAACAACTTGATACTCTGCAGAAATTGGCAAAACACTACACAGAACATGCTGATGGTTTATGCCACAAGTTAACAACTGTGTGTCCAACTGTGAAACCTCAGATTCAAGGTCTAGCAAAAGATGCTTGGGAAATCCCTTGATAATCTTTGCGACTAGAGGTTAAACTAGGACAAGGATGTTTTGGCAAAGTGTGGATGGGAATATGGAATGGAACCACAAAAGTAGCAATCAAAACACTAAAACCAGGTACAATGATGCCAGAAGCTTTTCTTCAAGAAGCTCAGGTAATGAAAAAAATAAGACATGGTAAACTTGTTCCACTATATGCTGTTGTTTCTGAAGAGCCAATTTACATTGTCACTGAATTGATGTCAAAAGGAAGCTTATTCAATTTCCTTAAGGAAGGAGATGGAAAGTATTTGAAGCTTCCACAAATGGTTGATATGCCTGCTCAGATTGCTGATGGTATGGCATATATTAAAAGAATGAACTATATTCACCGAGATCTCTGGGCTGCTAATATTCTTGTAGGAGAAAATCTTCTGTGCAAAATAGCAGATTTTGGTTTAGCAAGGTTAATTGAAGACAATGAATACACATCAAGACAAGGTGCAGAATTTCCAATCAAATGGACAGCTCCTGAAGTTGCACTGTATGGTGGGTTTACAATAAAGTCTGGTGTCTGCTCATTTGGAATTCTACAGACAGAACTGGTAACAAAGGGCAGAGTGCCATATCCAGGTATGGTGAACCATGAAATACTGGAACAGGTGGAGCGAGGATACAGGATGCCTTGCCCTCAGGGCTGTCCAGAATCCCTCCATGAATTGATGAATCTGTGTTGGAAGAAGGACCCTGATGAAAGACCAACATTTGAATATGTTCAGTCCTTCTTGGGAGACTACTTCACTGCTACAGAGCCATAGTACCAGCCAGGAGAAAACTTCTAATTCAAGTAGCCTATTTTATATGCTCACATCTGCCAAAATGTGAAGAACCTGTATAGAATTTCTACAGGGATCAAAAGAAGAAAATCTTCTTTACTCTGCACATTTTTAATGGTAAACTGGAGTCCCAGATATGGTTCCACAAAACCACTTTTTTTTACCCCAAGTATTAAACTTTAAAGTACGATGATGAATTTTCCAACCGATTTCAGGGTCCAAAGAAAATAGAGCTAAGATACTGATGACAGTGTGAGTGATAGCATGGTAATGAAGGACAGTGAGGCTACTGCTTATAAATCATTTTCTTTCTTTTCTTCCCCAAAGTCAGAATTGCTCAAAGAAAATTATTTATTGTTATAGATAAAACTTGAGTGATAAAAAGCTATACCATAATAAAATCTAAAATTAAAGAATATCATGGGACCAAATAATTCCATTCCAGTTTTTTAAACTTTCTTATATTTATTATTCTCAAAAGTTTTTTCTGAGTTAAATAGTCAATAGGCAATCTTAATATATGCCTCCTTTTGCATGGACATGGGCCAGGTTTTTCAAAAGGAATATAAACAGGATCTCAAACTTGATTAAATGTTAGACCACAGACGTGGAATTTGAAAGTATAATGCAGTACGTTAACATTCATATTAATGGAACTGAAAAGTAGAATAAGAAATTTTTCACTTCAGTCCTTTTCTGAAGAGTTTGACTTAGAATAATGAAGGTAACTGGAAAGTGACTTAATCTTGTATGAGGTTGCATTGAcAATTTTTTAAGGCAATATATAATTGAAACTGTACTATCCAATCCAAGGGGAAATCTTTTAATCTTTAGATAACATGCGGAGTAAGACCCAGCATTTAAAGAGCACTTTTAAAAAAATAGACTTGGTACTGTGAGATATTGCTAATATGTCCTTATGGTGATGGGTGCCACAAATAGAAAATAGAACCAGATCAGGGACTTGAATGCACTTTTGCTCATGTCGAAATAGATGAACAGAGAGAGTAAAATGTATTTCAAAGAAATACGAGAAAAGAAAATGTGAAAGTTTTACAAGAAGAGGGATGGAATGTAATGTTTAATGTTGATGTCATAGAGTGACAAAATGGCATTGTTGGCATTCATAGCTCCTCACTTAGCTATCTTCTGAGACTTTTAAGAGTTATAAGGTATAACTAACTATAAAACTAATTTTTCTTACACACTAAATGGGCATTATTTGTTCAAAATAGTGAAGTTTCGGCTTCACATTCATTCCAGTGGGATACGGCTTTTATGCAAAACATTTTTAGAACTCCAGTTTTCAAATCATGTTTGAATCTATATTCACTTTT
>NM_005433.4
GTCGTTGCTGCCGCCGGGCGCCCCGGGACGAGGAGGTGGAGGAGGGAGAGGGCCCGCGGGCCTCGCCTCCGCCCTCCGCCACCTCGAGCTGCGGTAGCAGCGACTCATGAGAGCGCGGCCGGAGGACAGATTTGATAATGGGCTGCATTAAAAGTAAAGAAAACAAAAGTCCAGCCATTAAATACAGACCTGAAAATACTCCAGAGCCTGTCAGTACAAGTGTGAGCCATTATGGAGCAGAACCCACTACAGTGTCACCATGTCCGTCATCTTCAGCAAAGGGAACAGCAGTTAATTTCAGCAGTCTTTCCATGACACCATTTGGAGGATCCTCAGGGGTAACGCCTTTTGGAGGTGCATCTTCCTCATTTTCAGTGGTGCCAAGTTCATATCCTGCTGGTTTAACAGGTGGTGTTACTATATTTGTGGCCTTATATGATTATGAAGCTAGAACTACAGAAGACCTTTCATTTAAGAAGGGTGAAAGATTTCAAATAATTAACAATACGGAAGGAGATTGGTGGGAAGCAAGATCAATCGCTACAGGAAAGAATGGTTATATCCCGAGCAATTATGTAGCGCCTGCAGATTCCATTCAGGCAGAAGAATGGTATTTTGGCAAAATGGGGAGAAAAGATGCTGAAAGATTACTTTTGAATCCTGGAAATCAACGAGGTATTTTCTTAGTAAGAGAGAGTGAAACAACTAAAGGTGCTTATTCCCTTTCTATTCGTGATTGGGATGAGATAAGGGGTGACAATGTGAAACACTACAAAATTAGGAAACTTGACAATGGTGGATACTATATCACAACCAGAGCACAATTTGATACTCTGCAGAAATTGGTGAAACACTACACAGAACATGCTGATGGTTTATGCCACAAGTTGACAACTGTGTGTCCAACTGTGAAACCTCAGACTCAAGGTCTAGCAAAAGATGCTTGGGAAATCCCTCGAGAATCTTTGCGACTAGAGGTTAAACTAGGACAAGGATGTTTCGGCGAAGTGTGGATGGGAACATGGAATGGAACCACGAAAGTAGCAATCAAAACACTAAAACCAGGTACAATGATGCCAGAAGCTTTCCTTCAAGAAGCTCAGATAATGAAAAAATTAAGACATGATAAACTTGTTCCACTATATGCTGTTGTTTCTGAAGAACCAATTTACATTGTCACTGAATTTATGTCAAAAGGAAGCTTATTAGATTTCCTTAAGGAAGGAGATGGAAAGTATTTGAAGCTTCCACAGCTGGTTGATATGGCTGCTCAGATTGCTGATGGTATGGCATATATTGAAAGAATGAACTATATTCACCGAGATCTTCGGGCTGCTAATATTCTTGTAGGAGAAAATCTTGTGTGCAAAATAGCAGACTTTGGTTTAGCAAGGTTAATTGAAGACAATGAATACACAGCAAGACAAGGTGCAAAATTTCCAATCAAATGGACAGCTCCTGAAGCTGCACTGTATGGTCGGTTTACAATAAAGTCTGATGTCTGGTCATTTGGAATTCTGCAAACAGAACTAGTAACAAAGGGCCGAGTGCCATATCCAGGTATGGTGAACCGTGAAGTATTAGAACAAGTGGAGCGAGGATACAGGATGCCGTGCCCTCAGGGCTGTCCAGAATCCCTCCATGAATTGATGAATCTGTGTTGGAAGAAGGACCCTGATGAAAGACCAACATTTGAATATATTCAGTCCTTCTTGGAAGACTACTTCACTGCTACAGAGCCACAGTACCAGCCAGGAGAAAATTTATAATTCAAGTAGCCTATTTTATATGCACAAATCTGCCAAAATATAAAGAACTTGTGTAGATTTTCTACAGGAATCAAAAGAAGAAAATCTTCTTTACTCTGCATGTTTTTAATGGTAAACTGGAATCCCAGATATGGTTGCACAAAACCACTTTTTTTTCCCCAAGTATTAAACTCTAATGTACCAATGATGAATTTATCAGCGTATTTCAGGGTCCAAACAAAATAGAGCTAAGATACTGATGACAGTGTGGGTGACAGCATGGTAATGAAGGACAGTGAGGCTCCTGCTTATTTATAAATCATTTCCTTTCTTTTTTTCCCCAAAGTCAGAATTGCTCAAAGAAAATTATTTATTGTTACAGATAAAACTTGAGAGATAAAAAGCTATACCATAATAAAATCTAAAATTAAGGAATATCATGGGACCAAATAATTCCATTCCAGTTTTTTAAAGTTTCTTGCATTTATTATTCTCAAAAGTTTTTTCTAAGTTAAACAGTCAGTATGCAATCTTAATATATGCTTTCTTTTGCATGGACATGGGCCAGGTTTTTCAAAAGGAATATAAACAGGATCTCAAACTTGATTAAATGTTAGACCACAGAAGTGGAATTTGAAAGTATAATGCAGTACATTAATATTCATGTTCATGGAACTGAAAGAATAAGAACTTTTTCACTTCAGTCCTTTTCTGAAGAGTTTGACTTAGAATAATGAAGGTAACTAGAAAGTGAGTTAATCTTGTATGAGGTTGCATTGATTTTTTAAGGCAATATATAATTGAAACTACTGTCCAATCAAAGGGGAAATGTTTTGATCTTTAGATAGCATGCAAAGTAAGACCCAGCATTTTAAAAGCCCTTTTTAAAAACTAGACTTCGTACTGTGAGTATTGCTTATATGTCCTTATGGGGATGGGTGCCACAAATAGAAAATATGACCAGATCAGGGACTTGAATGCACTTTTGCTCATGGTGAATATAGATGAACAGAGAGGAAAATGTATTTAAAAGAAATACGAGAAAAGAAAGTGAAAGTTTTACAAGTTAGAGGGATGGAAGGTAATGTTTAATGTTGATGTCATGGAGTGACAGAATGGCTTTGCTGGCACTCAGAGCTCCTCACTTAGCTATATTCTGAGACTTTGAAGAGTTATAAAGTATAACTATAAAACTAATTTTTCTTACACACTAAATGGGTATTTGTTCAAAATAATGAAGTTATGGCTTCACATTCATTGCAGTGGGATATGGTTTTTATGTAAAACATTTTTAGAACTCCAGTTTTCAAATCATGTTTGAATCTACATTCACttttttttgttttcttttttgagacggagtctcgctctgtcgcccaggctggagtgcagtggcgcgatctcggctcactgcaagctctgcctcccaggttcacaccattctcctgcctcagcctcccgagtagctgggactacaggtgcccaccaccacgcctggctagttttttgtatttttagtagagacgcagtttcaccgtgttagccaggatagtctcgatctcctgaccttgtgatctgcccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcgcccagccTACATTCACTTCTAAAGTCTATGTAATGGTGGTCATTTTTTCCCTTTTAGAATACATTAAATGGTTGATTTGGGGAGGAAAACTTATTCTGAATATTAACGGTGGTGAAAAGGGGACAGTTTTTACCCTAAAGTGCAAAAGTGAAACATACAAAATAAGACTAATTTTTAAGAGTAACTCAGTAATTTCAAAATACAGATTTGAATAGCAGCATTAGTGGTTTGAGTGTCTAGCAAAGGAAAAATTGATGAATAAAATGAAGGTCTGGTGTATATGTTTTAAAATACTCTCATATAGTCACACTTTAAATTAAGCCTTATATTAGGCCCCTCTATTTTCAGGATATAATTCTTAACTATCATTATTTACCTGATTTTAATCATCAGATTCGAAATTCTGTGCCATGGCATATATGTTCAAATTCAAACCATTTTTAAAATGTGAAGATGGACTTCATGCAAGTTGGCAGTGGTTCTGGTACTAAAAATTGTGGTTGTTTTTTCTGTTTACGTAACCTGCTTAGTATTGACACTCTCTACCAAGAGGGTCTTCCTAAGAAGAGTGCTGTCATTATTTCCTCTTATCAACAACTTGTGACATGAGATTTTTTAAGGGCTTTATGTGAACTATGATATTGTAATTTTTCTAAGCATATTCAAAAGGGTGACAAAATTACGTTTATGTACTAAATCTAATCAGGAAAGTAAGGCAGGAAAAGTTGATGGTATTCATTAGGTTTTAACTGAATGGAGCAGTTCCTTATATAATAACAATTGTATAGTAGGGATAAAACACTAACTTAATGTGTATTCATTTTAAATTGTTCTGTATTTTTAAATTGCCAAGAAAAACAACTTTGTAAATTTGGAGATATTTTCCAACAGCTTTTCGTCTTCAGTGTCTTAATGTGGAAGTTAACCCTTACCAAAAAAGGAAGTTGGCAAAAACAGCCTTCTAGCACACTTTTTTAAATGAATAATGGTAGCCTAAACTTAATATTTTTATAAAGTATTGTAATATTGTTTTGTGGATAATTGAAATAAAAAGTTCTCATTGAATGCACCTATTAATCGTTTTAGTTGCTATTCATATTCTCATTCGTTTTTTAAAAACTGATATATTCTGAATTTATTCTTCCATTGAGAAAAAAATGTTCAGTTACTTGTAACTACTGAGCAGAATTTAATCAATCCTTTATTAAATTCAGAACATTATTGAACTCA

Publications

PMID - Link Title