Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SNF8P1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:228352116-228352833  UCSC
Coordinates (T2T) chr2:228834309-228835026  UCSC
Coordinates (hg19) chr2:229216832-229217549  UCSC
Strand -
Parental Sequence NM_007241.4
Parental seq. overlap 656 bp
Parental seq. overlap (%) 32.1%
Genomic Region Intergenic
Retrocopy Summary SNF8P1, located on chr2:228352116-228352833, is a retrocopy of the parental gene SNF8. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SNF8
Full Name SNF8 subunit of ESCRT-II
Also known as Dot3|EAP30|VPS22
Coordinate chr17:48929316-48944842
Strand -
Gene summary The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SNF8P1
Bonobo Pan paniscus SNF8P1
Gorilla Gorilla gorilla SNF8P1
Orangutan Pongo abelii SNF8P1
Gibbon Nomascus leucogenys SNF8P1
Green monkey Chlorocebus sabaeus SNF8P1
Crab-eating macaque Macaca fascicularis SNF8P1
Rhesus Macaca mulatta SNF8P1
Baboon Papio anubis SNF8P1
Golden snub-nosed monkey Rhinopithecus roxellana SNF8P1
Marmoset Callithrix jacchus SNF8P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SNF8P1
AGTATAAGGAGCAAAGGACGGTCTTGGCTGAGGACCAGCTAGCCCAGATGTCAAAGCAGTTGGGCATGTTCAAGACCAACCTGGAGGAATTTGCCAGCAAGCACAAGCAGGAGATCCGGAAGGATCCTGAGTTCCATGTGCAGTTCCAGGACATGTGTGCAACCTTTGGGGTGGAGCCTTTGGCCTCTGGAAAAGGATTTTGATCTGAGATGCTGGGTGTGGGGGATTTTTATTACGAACTCGGTGTCCACATTACCAAAGTGTGCCTAGTGCTGAGCATTGGAGTGGAGGTCCAATAACTCTAGAGGAACTACATCAACAGGTGTTAAAAGGAAGGGGCAAGTTCACCCAGGATGTCAGTCAAGACAACCTGATCAGGGCCATCAAGAAACTAAAGGCACTTGGCACTGGCTTCAGCATCATCCCCATGAGTGGCACTTACCTCATTCAGTCTGTTCCAGCTGAATTCAATATGGATCACACCATGGGGCTGCAGCTGGCAGAGAAAAATGGCTATTGACTGTCAGAGAGATCAAAGCCAGTCTTAAATGGGAGAACCAATGAGCAGGGCAAGTGCCAGAACACCTGCTGAGAGAAGGGCTGGCGTGGCTGGACTTACAGGCCCCAGGGGAGATCCACTACTGGCTGCCAGCTCTCTTCACTGACCTCTACTCCCAGGAGATTACAGCTGAGGAAGCCAGAGAAGTCTTCCCCTGAG
>NM_007241.4
GCAGATGACGCGCGGCTCGGGCTTCCGCCTTGGGGAGCCGGCGGCGGAGTCCGGGACGTGGAGACCCGGGGTCCCGGCAGCCGGGCGGCCCGCGGGCCCAGGGTGGGGATGCACCGCCGCGGGGTGGGAGCTGGCGCCATCGCCAAGAAGAAACTTGCAGAGGCCAAGTATAAGGAGCGAGGGACGGTCTTGGCTGAGGACCAGCTAGCCCAGATGTCAAAGCAGTTGGACATGTTCAAGACCAACCTGGAGGAATTTGCCAGCAAACACAAGCAGGAGATCCGGAAGAATCCTGAGTTCCGTGTGCAGTTCCAGGACATGTGTGCAACCATTGGCGTGGATCCGCTGGCCTCTGGAAAAGGATTTTGGTCTGAGATGCTGGGCGTGGGGGACTTCTATTACGAACTAGGTGTCCAAATTATCGAAGTGTGCCTGGCGCTGAAGCATCGGAATGGAGGTCTGATAACTTTGGAGGAACTACATCAACAGGTGTTGAAGGGAAGGGGCAAGTTCGCCCAGGATGTCAGTCAAGATGACCTGATCAGAGCCATCAAGAAACTAAAGGCACTTGGCACTGGCTTCGGCATCATCCCTGTGGGCGGCACTTACCTCATTCAGTCTGTTCCAGCTGAGCTCAATATGGATCACACCGTGGTGCTGCAGCTGGCAGAGAAGAATGGCTACGTGACTGTCAGTGAGATCAAAGCCAGTCTTAAATGGGAGACCGAGCGAGCGCGGCAAGTGCTGGAACACCTGCTGAAGGAAGGGTTGGCGTGGCTGGACTTACAGGCCCCAGGGGAGGCCCACTACTGGCTGCCAGCTCTCTTCACTGACCTCTACTCCCAGGAGATTACAGCTGAGGAGGCCAGAGAAGCCCTCCCCTGACTGCATGTGGAAGGGCACACAGCAGCAGGCAGGGAGGAGGCGGAGGTGGCAAATAAACCTGGGCAATTTTGTTTATACAAAAAATAGAAAAAAAGTTCCAAGTTTTTCTTTCTTCCCTCATTCTTTTATTTTTGAAAAGTGCCTTCACGTTGCATTTTTATTGGAGGAAAACCTCGCTCGTTCAGTAAGCATAATCTGATTAACACAGAGAACGGCAAGCACATAtaaaatgatttttgtaggtcatctgcaagttcatggaagagctgggcctagaatgtgggttgtttcctggcctgtctagtctttgTAGCTGTGAGACATAGATTACAGCCTATGCTAATTCAAACCTTTTAAATAAAATGTTCCTTATCTCAAACTAGCTGGTCCTAATGGACCAGTAAATAATATTCACTTTCAGTCTCTTCTGGCTTCCTCTGTAGAGGCTCTAGGTTATGACAGAGTTAGCTGTGAGTATGAAGGAAATAGAAGTCAATGTCCAATCGTGGCTAAATTGGAGGAAAGAAAACAATGGAATCTGAGGGGAATCAAACAATAGTTAGGGAATGTTCTATTTTCTTAAATTCCCTACTAGCTTTCTCACCCTCCTGTAGTGATTGCCAGGTCCCTCTAGCCTCAGTAGTGGGAAAGGGAGTCATTTACTGAACACCTACCCTGTGCCATTTTACATACAGCTCACTTAAATTTCACCAAGTAGGCAGCCTTCAACATCACAGGTGATTCAATCAAAGTAATTTGCCAGGGGCCGCCAGCTTCAGCCGAGCTAAAGCTGGTGCCTAGGCCTATTAACCCGAGCCCATGCCTTCATGTATCACTGCATAGTACAGAATGGCAGCACATACTGTGTGTAGACATTTTTCTACACACGTGGTCAGCCAAGAGTAAAAGCCTCTGCATCAGAAAGCAAGAATCTCCTATAGCAAGTAGAAGTGGTGATGAGGGAAGAGGCCAGAGTTGTTTAAGGCTCCCAAAGTCCTTATGGTCTAAAGGCTAAGATCCTAAAAGTGCTAGTTTAGTACTGGAAATCTGAAAACTCAATGGTTTTTCCATACTGAGACCCTTCCTTTAGCAGGATATAGCCTGGGCCCATCTCTTCCTCTGCCTATCCTTGTAGGACATGCTCACTCCAAGCTCTGGA

Publications

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