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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name JTBP1
Plot displaying the genomic locations of a retrocopy (in chr22) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr22:40798048-40798374  UCSC
Coordinates (T2T) chr22:41270238-41270564  UCSC
Coordinates (hg19) chr22:41194052-41194378  UCSC
Strand +
Parental Sequence NM_006694.4
Parental seq. overlap 266 bp
Parental seq. overlap (%) 20.9%
Genomic Region Intragenic (SLC25A17)
Retrocopy Summary JTBP1, located on chr22:40798048-40798374, is a retrocopy of the parental gene JTB. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name JTB
Full Name jumping translocation breakpoint
Also known as HJTB|HSPC222|PAR|hJT
Coordinate chr1:153974269-153977674
Strand -
Gene summary Enables protein kinase binding activity. Involved in mitotic cytokinesis and positive regulation of protein kinase activity. Located in cytoplasm and midbody. Colocalizes with centrosome and spindle. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Orangutan Pongo abelii JTBP1
Green monkey Chlorocebus sabaeus JTBP1
Crab-eating macaque Macaca fascicularis JTBP1
Baboon Papio anubis JTBP1
Golden snub-nosed monkey Rhinopithecus roxellana JTBP1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Rhesus Macaca mulatta Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>JTBP1
CATTTCCAGGCTAAAGTCACCCCAGAGTGTGGCTTCACAGGGTGTGTGGAGAAAACCGCAAGCAGCTCATCTAAGGAATGAGTTTGAAAGCCTCCCGCTTGGCTCTGATGGAAATACACCTGTTCTGGAAATTCGAAGGGGCTGTTGATATGGTCTTGATCTTTGCCTGTCTTGTCATCAGTTGTCAGCAACAACTGGGCAAAAAGCTCTGGAAAAGCTCTGGAGGCAAATTGAGTCCACAGAGCTACAGTCCACCCTTTACCCTGGGTCTTAGAGAACTCATCTCAGACAGAGAAAGCAACATGGCCTGATGTGCACCATTGGTTC
>NM_006694.4
ACCGACGCGGAAGACTATAAGCCCCAGCGGGCGACGACCGAACGCCCCCGGGAACACCGGGCCCCGAGCTCGGTCCCGCGCCCGAGGATCCTCCACGGGGCTAGATGGCTGCGTCGGGGGCGGGAGCGGAGGTGAGCGGGCGCTAGGGCCGCGAGCCCCCGCCGGCCCTTCCTCCAGCGCCCTGCGGACCCCGCAGAAGGCGCTCGCCTCCCTAGCCCGCAAAAACATATCGATTTTTCTCGCTGTGGCAACGGGGACGTCCTGATAGATCCTCTGCTCCAATAGGCAACTCCGGCCTTCCCTGCCCTGACCTGGAACCTCTGGGAGGGCTGCAGAGTAAGTGCCGCCTCTGCGCTCCGACGGAGGCACGAGGCCTGTGGAGTAGGTCCCTCTGTTCCGACAGGTGCGACACTTGGCGCTCCATGCTTGCGGGTGCCGGGAGGCCTGGCCTCCCCCAGGGCCGCCACCTCTGCTGGTTGCTCTGTGCTTTCACCTTAAAGCTCTGCCAAGCAGAGGCTCCCGTGCAGGAAGAGAAGCTGTCAGCAAGCACCTCAAATTTGCCATGCTGGCTGGTGGAAGAGTTTGTGGTAGCAGAAGAGTGCTCTCCATGCTCTAATTTCCGGGCTAAAACTACCCCTGAGTGTGGTCCCACAGGATATGTAGAGAAAATCACATGCAGCTCATCTAAGAGAAATGAGTTCAAAAGCTGCCGCTCAGCTTTGATGGAACAACGCTTATTTTGGAAGTTCGAAGGGGCTGTCGTGTGTGTGGCCCTGATCTTCGCTTGTCTTGTCATCATTCGTCAGCGACAATTGGACAGAAAGGCTCTGGAAAAGGTCCGGAAGCAAATCGAGTCCATATAGCTACATTCCACCCTTGTATCCTGGGTCTTAGAGACCCTATCTCAGACAGTGAAAGTGAAATGGACTGATTTGCACTCTTGGTTCTTTGGAGCCTTGTGGTGGAATCCCCTTTTCCCCATCTTCTTCTTTCAGATCATTAATGAGCAGAATAAAAAGAGTAAAATGGTTTCCTTCCCTTCTGTAACTTGGAGCAGGAAGTCATGGGGGCAGAGAGGGAAAGGAGGTGGTTACTTAAGGCCCCAATCTACCAAGTCTTCCCCACCACTTCTCCCTTGTTTTCCCCCTCTTCTACTACTTATTTCAAACTTCTGGGATACAATTTCAGCTAAAACGTTTATTTCTCACTCAAAACTTATTTCCCCTCAACCCTATACCCAAAGAAGAAATAAAATCACAGATACATAACAGAA

Publications

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