Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name SLC25A5P1
Plot displaying the genomic locations of a retrocopy (in chr22) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr22:42000444-42002033  UCSC
Coordinates (T2T) chr22:42480051-42481640  UCSC
Coordinates (hg19) chr22:42396448-42398037  UCSC
Strand -
Parental Sequence NM_001152.5
Parental seq. overlap 930 bp
Parental seq. overlap (%) 65.1%
Genomic Region Intragenic (WBP2NL)
Retrocopy Summary SLC25A5P1, located on chr22:42000444-42002033, is a retrocopy of the parental gene SLC25A5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SLC25A5
Full Name solute carrier family 25 member 5
Also known as 2F1|AAC2|ANT2|T2|T3
Coordinate chrX:119468444-119471396
Strand +
Gene summary This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SLC25A5P10
Bonobo Pan paniscus SLC25A5P10
Gorilla Gorilla gorilla SLC25A5P11
Orangutan Pongo abelii SLC25A5P10
Gibbon Nomascus leucogenys SLC25A5P4
Green monkey Chlorocebus sabaeus SLC25A5P9
Crab-eating macaque Macaca fascicularis SLC25A5P8
Rhesus Macaca mulatta SLC25A5P8
Baboon Papio anubis SLC25A5P12
Golden snub-nosed monkey Rhinopithecus roxellana SLC25A5P11
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SLC25A5P1
GGACTCAATTATGTTTTTTATTTCAGTCACTCCTAATAAATAACAAATTTGGAGAAATAAAAATATCTTTATCTTGAGCATTCTTGACAGACTCCTCGCTGTCAATTTATCAGTGGCAACTATTCACTGGTTGGAAATGGGAAGCAATAATAGTCATCTGACCAGTTTTCTCTTAAAGCCATTTCTATAAGCAATACAAGGGCATTAGAGACTGCATGGTCTGTATTCCCAAGGAGCACGGAGTCCTGTCCTGGTGCGGTAACCTGGCCAGTGTCATCAGATACTTCCCCCACCCAGGCTCTTAACTTCACCTTCAAAGATAAATACAAGCAGATCTTCCTGGATGGTGTGGACAAGAGATCCCAGTTTTGGCGCTACTTTGCAGGGAATCTGGCATCAGGCGGTGCCACTGGGGCCACATCCTTGTGTTTTGTGTACCCTCTTGATTTTGCCCATACTCGTGTAGCAGCTGATGTGGGCAAAGCTGGAGCTGAAAGGGAATTGCGAGGTTTCGGTGACTGCCTAGTTAAGATCTACAAATCTGACGGGATTAAGAGCCTGTACCAAGGCTTTAACGTGTCTGTGCAGGGTATTATCTACCGAGCTGCCTGCTGCCTACTTCGGTAACTATGACACTGCAAAGGGAATGCTTCCGGATCCCAAGAACACTCACATTGTCATCAGTTGGATGATGCACAGACTGTCACTGCCGTTGCTGGGTTGACTTCCTATTCATTTAACACCATTTGCTGCTACATGATGATGCAGTCAGGATGCAAAGGAACTGACATCATGTACACAGGCACATTTGACTGCTGGAGGAAGATTACTCATGATGAAGGAAGCAAAGCTGTTTTCAAGGGTGCATGGTCCAGTGTTCTCAGAGGCATGGGTGGTGCTTTTGTGCTTGTCTTGTATGATGAAACCAAGAAGTACATGTAAGTTATTTCCTAAGATTTTTCCCCCTTTGAACAGGCATGTTGTATTATATGACATATCTTGAGCACAGCCCCGGAGTCAAAGCCGATTCTCGGACCAGTCCCATCCCACAGCAGCCTGCCTCCTCTTTCGACATCACAGAGGCTGCTGTGTCCTTCGCCAAGGACTCCCTGGCAGGTGGAGTGGCCGCAGCCATCTCCAAGATGGCGGTAGCACCCATCGAGCGGGTCAa
>NM_001152.5
CCCCGCAGCGCCGGAGTCAAAGCCGGTTCCCGGCCCAGTCCCGTCCTGCAGCAGTCTGCCTCCTCTTTCAACATGACAGATGCCGCTGTGTCCTTCGCCAAGGACTTCCTGGCAGGTGGAGTGGCCGCAGCCATCTCCAAGACGGCGGTAGCGCCCATCGAGCGGGTCAAGCTGCTGCTGCAGGTGCAGCATGCCAGCAAGCAGATCACTGCAGATAAGCAATACAAAGGCATTATAGACTGCGTGGTCCGTATTCCCAAGGAGCAGGGAGTTCTGTCCTTCTGGCGCGGTAACCTGGCCAATGTCATCAGATACTTCCCCACCCAGGCTCTTAACTTCGCCTTCAAAGATAAATACAAGCAGATCTTCCTGGGTGGTGTGGACAAGAGAACCCAGTTTTGGCTCTACTTTGCAGGGAATCTGGCATCGGGTGGTGCCGCAGGGGCCACATCCCTGTGTTTTGTGTACCCTCTTGATTTTGCCCGTACCCGTCTAGCAGCTGATGTGGGTAAAGCTGGAGCTGAAAGGGAATTCCGAGGCCTCGGTGACTGCCTGGTTAAGATCTACAAATCTGATGGGATTAAGGGCCTGTACCAAGGCTTTAACGTGTCTGTGCAGGGTATTATCATCTACCGAGCCGCCTACTTCGGTATCTATGACACTGCAAAGGGAATGCTTCCGGATCCCAAGAACACTCACATCGTCATCAGCTGGATGATCGCACAGACTGTCACTGCTGTTGCCGGGTTGACTTCCTATCCATTTGACACTGTTCGCCGCCGCATGATGATGCAGTCAGGGCGCAAAGGAACTGACATCATGTACACAGGCACGCTTGACTGCTGGCGGAAGATTGCTCGTGATGAAGGAGGCAAAGCTTTTTTCAAGGGTGCATGGTCCAATGTTCTCAGAGGCATGGGTGGTGCTTTTGTGCTTGTCTTGTATGATGAAATCAAGAAGTACACATAAGTTATTTCCTAGGATTTTTCCCCCTGTGAACAGGCATGTTGTATTATATAACATATCTTGAGCATTCTTGACAGACTCCTGGCTGTCAGTTTCTCAGTGGCAACTATTTACTGGTTGAAAATGGGAAGCAATAATATTCATCTGACCAGTTTTCTCTTAAAGCCATTTCCATGATGATGATGATGGGACTCAATTGTATTTTTTATTTCAGTCACTCCTGATAAATAACAAATTTGGAGAAATAAAAATATCTAAAATAAATTTTGTCTGCAGTATATTTTCATATAAAAATGCATATTTGAGTGCTACATTCGAATAAATACTACCTTTTTAGTGAA

Publications

PMID - Link Title