Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name OLA1P1
Plot displaying the genomic locations of a retrocopy (in chr22) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr22:42107349-42109034  UCSC
Coordinates (T2T) chr22:42586945-42588631  UCSC
Coordinates (hg19) chr22:42503353-42505038  UCSC
Strand -
Parental Sequence NM_013341.5
Parental seq. overlap 1642 bp
Parental seq. overlap (%) 38.6%
Genomic Region Intergenic
Retrocopy Summary OLA1P1, located on chr22:42107349-42109034, is a retrocopy of the parental gene OLA1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name OLA1
Full Name Obg like ATPase 1
Also known as DOC45|GBP45|GTBP9|GTPBP9|PTD004
Coordinate chr2:174072447-174248532
Strand -
Gene summary This gene encodes a member of the GTPase protein family. The encoded protein interacts with breast cancer-associated gene 1 (BRCA1) and BRCA1-associated RING domain protein (BARD1), and is involved in centrosome regulation. Overexpression of this gene has been observed in multiple types of cancer and may be associated with poor survival. Pseudogenes of this gene have been defined on chromosomes 17 and 22. [provided by RefSeq, Jun 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes OLA1P3
Bonobo Pan paniscus OLA1P2
Gorilla Gorilla gorilla OLA1P3
Orangutan Pongo abelii OLA1P3
Gibbon Nomascus leucogenys OLA1P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>OLA1P1
CTTCCTCCCCGCCTCTGGCTGCCGGCAGGACCTTTCTCTCGCTGCTACTGGGACCCCGTGTCATAGCCCAGGCTGAGCACGATGCCCCCTCAAAAGGGAGGTGATGGAATTAAACCACCCCCAATCATTGGAAGATTTGGAACCTCACTGAAAATTGGTATTGTTGGATTGCCAAATGTTGGGAAATCTACTTTCTTCAATGTATTAACCAATAGTCAGGCTTCAGCAGAAAACTTCCCATTCTGCACTATTGATCCTAATGAGAGCAGAGTACCTGTGCCAGATGAAAGGTTTGACTTTCTTTGCCAATATCACAAACCAGCAAGCAAAATTCCTGCCTTTCTAAATGTAGTGGATATTGCTGGCCTTGTGAAAGGAGCTCACAATGGGCAGGGCCTGGGGAATGCTTTTTTATCTCATTTTAGTGCTTGTGATGGCATCTTTCATCTAACACGTGCTTTTGAAGATGATGATATCACACATGTTGAAGAAAGTGTAGATCCTATTCGAGATATAGAAATAATACATGAAGAGCTTCAGCTTAAAGATGAGGAATGACTGGGCCCATTATAGATAAACTAGAAAAGGTGGCTGTGAGAGGAGGAGATAAAAAACTAAAACCCAAATATGATATAATGTGCAAAGTAAAATCCTGGGTTATAGATCAAAAGAACCTGTTCGCTTCTATCATGATTGGAATGACAAAGAGATTGAAGTGTTGAATAAACACTTATTTTTGACTTCAAAACCAATGGTCTACTTGGTTAATCTTTCTGAAAAAGACTACATTAGAAAGAAAAACAAATGGCTGATAAAAATTAAAGAGTGGGTGGACAAGTATGACCCAGGTGCCTTGGTCATTCCTTTTAGTGGGGCCTTGGAACTCAAGTTGCAAGAATTGAGTGCTGAGGAGAGACAGCAGTATCTGGAAGCGAACATGACACAAAGTGCTTTGCCAAAGATCATTAAGGCTGGGTTTGCAGCACTCCAACTAAAATACTTTTTCACTGCAGGCCCAGATGAAGTGCGTGCACGGACCATCAGGAAAGGGACTAAGGCTCCTCAGGCTGCAGGAAAGATTCACACAGATTTTGAAAAGGGATTCATTATGGCTGAAGTAATGAAATATGAAGATTTTAAAGAGGAAGGTTCTGAAAATGCAGTCAAGGCTGCTGGAAAGTACAGACAACAAGGCAGAAATTATATTGTTGAAGATGGAGATATTATCTTCTTCAAATTTAACACACCTTAACAACTGAAGAAGAAATAAAATTTAGTTACTGCTCAGATAAACATACAACTTCCAAAAGGCATCTGATTTTTTAAAAATTAAAATTTCTGAAAACCAATGGGACAAATAAAGTTGGGGAGATGGGAATCTTTGACAAACAAATTATTTTTGTTTTAAAATTAAAATACTGTGTACCCTCTCCCCCCAATGAAATGCAAGTTCACTAAATGTGAACACCTTTGCTTTTCATGTGATTAAGACCCTACTCCAAATTATAGAAGCTTTTCAAGAACCATGTTACTCTCATGATACTTCATTAATCTCCATCATGTATGCCAAGCCTAACACATTTGACAGTGAGAACAATGTGGCTTGCTCCTTTTTGAATCTACAGATAATGCATGTTTTATAGTACTCCAGATGTCTACACTCAATAAAACATTTGACAAAACCAA
>NM_013341.5
CTTCCTCCCCGCCTCCAGCTGCCGGCAGGACCTTTCTCTCGCTGCCGCTGGGACCCCGTGTCATCGCCCAGGCCGAGCACGATGCCCCCTAAAAAGGGAGGTGATGGAATTAAACCACCCCCAATCATTGGAAGATTTGGAACCTCACTGAAAATTGGTATTGTTGGATTGCCAAATGTTGGGAAATCTACTTTCTTCAATGTGTTAACCAATAGTCAGGCTTCAGCAGAAAACTTCCCGTTCTGCACTATTGATCCTAATGAGAGCAGAGTACCTGTGCCAGATGAAAGGTTTGACTTTCTTTGTCAATACCACAAACCAGCAAGCAAAATTCCTGCCTTTCTAAATGTGGTGGATATTGCTGGCCTTGTGAAAGGAGCTCACAATGGGCAGGGCCTGGGGAATGCTTTTTTATCTCATATTAGTGCCTGTGATGGCATCTTTCATCTAACACGTGCTTTTGAAGATGATGATATCACGCACGTTGAAGGAAGTGTAGATCCTATTCGAGATATAGAAATAATACATGAAGAGCTTCAGCTTAAAGATGAGGAAATGATTGGGCCCATTATAGATAAACTAGAAAAGGTGGCTGTGAGAGGAGGAGATAAAAAACTAAAACCTGAATATGATATAATGTGCAAAGTAAAATCCTGGGTTATAGATCAAAAGAAACCTGTTCGCTTCTATCATGATTGGAATGACAAAGAGATTGAAGTGTTGAATAAACACTTATTTTTGACTTCAAAACCAATGGTCTACTTGGTTAATCTTTCTGAAAAAGACTACATTAGAAAGAAAAACAAATGGTTGATAAAAATTAAAGAGTGGGTGGACAAGTATGACCCAGGTGCTTTGGTCATTCCTTTTAGTGGGGCCTTGGAACTCAAGTTGCAAGAATTGAGTGCTGAGGAGAGACAGAAGTATCTGGAAGCGAACATGACACAAAGTGCTTTGCCAAAGATCATTAAGGCTGGGTTTGCAGCACTCCAACTAGAATACTTTTTCACTGCAGGCCCAGATGAAGTGCGTGCATGGACCATCAGGAAAGGGACTAAGGCTCCTCAGGCTGCAGGAAAGATTCACACAGATTTTGAAAAGGGATTCATTATGGCTGAAGTAATGAAATACGAAGATTTTAAAGAGGAAGGTTCTGAAAATGCAGTCAAGGCTGCTGGAAAGTACAGACAACAAGGCAGAAATTATATTGTTGAAGATGGAGATATTATCTTCTTCAAATTTAACACACCTCAACAACCGAAGAAGAAATAAAATTTAGTTATTGCTCAGATAAACATACAACTTCCAAAAGGCATCTGATTTTTAAAAAATTAAAATTTCTGAAAACCAATGCGACAAATAAAGTTGGGGAGATGGGAATCTTTGACAAACAAATTATTTTTATTTGTTTTAAAATTAAAATACTGTGTACCCCCCCCCCCCCATGAAATGCAGGTTCACTAAATGTGAACAGCTTTGCTTTTCACGTGATTAAGACCCTACTCCAAATTGTAGAAGCTTTTCAGGAACCATATTACTCTCATGATACTTCATTAATCTCCATCATGTATGCCAAGCCTGACACATTTGACAGTGAGGACAATGTGGCTTGCTCCTTTTTGAATCTACAGATAATGCATGTTTTACAGTACTCCAGATGTCTACACTCAATAAAACATTTGACAAAACCAGCCTTGGTGTGTTTGGGGATGTCTGTATTGACTGACTGTGGTGTGCTGAATGCGATACGGCACCTGGTGGTTGCTGATTACAGAATTTTAAGGCGTGTGTATGACACAGTAACTGGCAGTGTGGGGCAGCTGCAATTGTATCTTAAAAGTGAGTCTTTCATGGGAATCAGAAGAATAGTATACCAGGGATTTGTCTCAAAAAAGTTAATTAATTTATAGATCAACATTTATTGAAAGATGATAGCAATGATATTATGAGGGATATGAGATAGGTGACTGACCACAAAGAAGAAAATTCTGTCTCAAAAATTAAAGAATTTTGTTTGTTATTGTTGTTCTGACCATATTGAAAAGAGGTTCACTTTTAATCTTTCCTTTGAAATTATTAAATTGTAAAAACTGACCCATTGATGTCTGGTGGGTTATGTTTTGCTTCAATTCAGCAATGTGTATAAAAGTTCCTACACTGATTTTGAAATACTAAGATCAGACTTTGAAAATTTTAAAAATTCTTTCATTCTTACTTTTCAGATATTTGAGAGCAGTCGAAGTGGTAGTATGGGTAAGTTAAGCACTTCTTAACATTGTAGCAGAAAATTCCAAAAGAAAGACTAGAACAAATTGGTAATTTGGAGACCCTTTGCCACTTAGCCTTCTCTTGTGATGATGGCCTGAAAGCTCTCTCGGCCCTGAGCCTCCCTTTCTCTCCCATGTTTCCATTCCTGTGAGACCTCCCTTCCTTGTCCTTGTCCTCTGCCCTTTTGTGCTCTTCTGTGATCACAGGACCATTTCCATGGAATGCAGATTCATACCCAGCCAGCCTTTGCCTCTACTGTATCGCTTTGGGACTTTAAAGATGCAGAAGTATTAGAACACACACAAACTTAAAATGGAAAGTTACCAAATGTAGCACTAGAGGCAAGAAAAGGGGTGATTTTTTAAAGATTTGGCTATACTTAAGATATTTAAAGAGGATGAGGTTGAGTCGTGAGTATAATTTAGAAGCTCTCCAGTGAGTATTTTTTTAGTATCAAATAGTGATCTTCTTTTGCTAACATAAAAATGAGTAAACTACAGCAGAGAAATAAGAATAAAACTAATGAAGGGTTTTTTAAAAGAACTAAATAAAACAAATAAAACTAGGCTACAGGTATAGCTGACCAAGTTTGCTGTGAAAAATCCTTGTTATATCTATTTCTGTATTGGAGTAATGTGTAGATTAGTGGATTGTTAGGGATTTCAGCAGTATAAGAAAGAATCAAATATCTTGCTTTTGGGTCTTCTCCAAAGTAAATTGCATGGACTTCTTAAAGAAGTTTGAAATCAGTAAAAAGACATTAGGATCATGCAATTTTACTTTGTCTAGCTTCTAATGTGGTAAATTGCACATTGTGCAACAGAACCATTAATAAAAGAAAGGAGTTAGTTTTGAGGTAACTGCATTCATTAGGGGCTGAAAATAAATGTTAAAAATGTTTAATTTGGTTAGAAGTTCTACAACATTGTATGTACATATACAAAATTTCATTTTCTCTGAAAGTCGAGAATTCCAAGAACTGTTACATATAATCATATATATGCCTATATCTAAACGTTTTCCCTCCTTTAATATTGATAAAGTTAATATATTTTAGGATGTTATGTAAATATTTTTGCATGTATCTGTAGCTCCATCTTAATCAAATTTATGGTTAAAAGAGATTTGAggccaggcgtggaggctcacacctataatcccaacactttgggaggccgaggtgggaggatcacttgagcacaggagtttgagaccagcctgtgcaacatcatgaaacatcatctctacataaaaaaatacatatatacaaaaattagctgggcatcatggcacacacctgtagtcccagctacttaggaggctgagatgggaggattgatcgatcgcttgagcctgggaggtggaggctactgtgagccatgatcatgccactgcactccagcctgggcaacagagtgagaccctgtctccaaagagaaagagaaaCTTGAGAAGGCTTGTGCCCAAAGCTTGAAGAAAGATTGTAATAGCATTTAGTTGTGTTTTATCATGTTATCTTCATAACATGCATTTTGCATATGGCTCAGAGCAGAGCCGGATCTCCCAAGGAAGCACAAATAGTTTTTGTCGCTAACTTAGTTATGAGTGAAGCCTCTGTTCACTTATAACTTGCCAGTTTCATTGGTGGAATAAGTCCCCTTACTCATGATTCATCAATATTCCTATATTAAAATTCCAGTTTGATGTTTGTCTCTAGTTGTCTGTGTATAATATTTCCAAAGCTCCTTTGTAAACCCCGTCTCCTTTCATTCAGAGAGTCAGAGACGGTATCTCCTCCTCCTGCCTCTTCTATTGTTCTGATTAGTCTACTTAAATTCACTTGATGCTCTTTTTATTTTACAAGAGACTTGAGAAATGTCGGTTGTTCCTAATGGCAAACTACTTTAGCTGGGAAAATTCATTTCAACTTATTTTAAGCTTGTAAAATACACTGTGGTGATAAAATAAAAGAGCTGGGTTTGA

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