Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name STRAPP1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:37816685-37818469  UCSC
Coordinates (T2T) chr2:37823665-37825448  UCSC
Coordinates (hg19) chr2:38043828-38045612  UCSC
Strand +
Parental Sequence NM_007178.4
Parental seq. overlap 1664 bp
Parental seq. overlap (%) 88%
Genomic Region Intergenic
Retrocopy Summary STRAPP1, located on chr2:37816685-37818469, is a retrocopy of the parental gene STRAP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name STRAP
Full Name serine/threonine kinase receptor associated protein
Also known as MAWD|PT-WD|UNRIP
Coordinate chr12:15882382-15903478
Strand +
Gene summary Enables RNA binding activity. Involved in maintenance of gastrointestinal epithelium; negative regulation of transforming growth factor beta receptor signaling pathway; and spliceosomal snRNP assembly. Located in cytosol. Part of SMN complex. Implicated in adenocarcinoma; colorectal carcinoma; large cell carcinoma; lung carcinoma; and squamous cell neoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes STRAPP1
Bonobo Pan paniscus STRAPP1
Gorilla Gorilla gorilla STRAPP1
Orangutan Pongo abelii STRAPP1
Gibbon Nomascus leucogenys STRAPP2
Green monkey Chlorocebus sabaeus STRAPP1
Crab-eating macaque Macaca fascicularis STRAPP2
Rhesus Macaca mulatta STRAPP2
Baboon Papio anubis STRAPP2
Marmoset Callithrix jacchus STRAPP3
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>STRAPP1
TCTCCCTTTCCCTCCCTGGTCGACTGTTACTTGCCCATGTCAGACTCCCTGACCCCTCCGTCACCCCTTCCTAACCTCAGTGCCACCAGATTGTCCTCCTTTTCCTGTTTTGCAGCCCAGCCCTAGTGTCAGGGCGGGGGCCTGGAGGAGCCCAAGGTGCTGCAGCAGAAGAGAGAAAAGAGAACGACAACACTCAGCTCGCCAGTCTGGTCGCTGGGTTCACTGCCACCATGGCAATGAGACAGACGCTGCTCACCTACTTTGGCCACACGTGGCCCATGGTTGATTTGGCCTTCAGTGGCATCACGACTTATGGGTATTTCTTAACCAGCGCTTACAAAGATGGTAAACCTATGCTACGCCAGGGAGATACAGGAGACTGGATTGGAACATTTTGGGGTCATAAAGGTGCTGTTTGGGGTGCAACACTGAATGCCACCAAAGCAGCAACAGCAGCTGCAGATTTCACAGCCAAAGTGTGGGATGCTGTCTTAGGAGATGAATTGATGACCTTGGCTCATAAATACATTGTCAAGACTGTGTATTTCATGCAGGATAGTAATTATTTGTTAACCAAGGGACAGGATAAACTGTTACGCATGTATGACTTGAACAAACCCAAAGCAAGACCTAAGGAAATTAGTGGTCACACTTCTGGTATAAAAAAAAGGCTCCTATGGTGCAGTGAGGATAAACAGATTCTTTCTGCTGATGACAAAACTGCTCGACTTTGGGATCATGCTACTATGACAGAAGTGAAATCTCTAAATTTTAATATGTCTGTTAGTAGTACAAAATACATTCCTGAGGGAGAGATTTTGGTTATAACTTATGGACTATCTATTGCTTTTCATAGTGCAGTAAGTTTGGACCCAATTACATCCTTTGAAGCTCCTGCAACCATCAATTCTGCATCTCTTCATCCTGAGAAAGAATTTCTTGTTGCAGGTGGTGAAGATTTTAAACTTTATAAGTATTTTAACCATGGAGAAGAATTCGAATCCTACAAGGGATACTTTGGTCCTATTCACTGTGTGAGATTTAGTCGTGATGGAGAACTCTATGCCAGTGGTTCTGAAGATGGAACATTGAGACTAGGGCAAACTGTGGTAGGAAAAACATACGGCCTTTGGAAATGTGTGCTTCCTGAAGAAGAGAGTGGTGAGCTGGCAAAGCCAAAGATTGGCTTTCCAGAGACAACAGAAGAGGAGCTAGAAGAAATTGTTTCAGAGGATTCAGATTGCATCTATTCTTCAACTCCTGATGTTAAGGCCTGAGGGTCAATCATATGCTGCAGTTAGTATCCAACTGATGGACTAAAACGAGCAAGCAGAGAAAAGCATCAGCCTTCCAGAGTTACTCTCTGCTTAAGGCAGAAAGAGCAGTAAATAATGGGGAAAATGAATTAGCTCCAGTGCTGGAACAACTAACTTGGTGTTACCTGTAAGTGAAAACTCAAGAGTATCAGATGAAGAGAGGTAGAGTTATCCTCTTGTAGTACAGTGGCCTGTTATCTTTTTAATGAATATATACAAGCCAACATCCAATTTCTCTTATTACAGTTAGGGTTCTTGTAGCTGTTTATGTTATTATGGAGAAGAAAAATATATTGGCTTATTTTTCTGACTTTTTTCCTTAAAGCAGAATGCCTTTGTTTGTTTGCTTTAGTTGTAAAAAAGAGGGAATACATGATAAAGTAACTGGTTTGATTTCTCTTTCATTGTACACTGCTTCTGAACATTTAATTGTTTTTAGTTGTCTAAATGAAATGCCTCTAAAACAAAA
>NM_007178.4
CGTCGTCACTTCCTGCCGATGCCGGTGTGGACGCTGTGAATCGTGGCTGGCCCGGTTCTCCGCTTCTCCCCATCccctactttcctccctccctccctttccctccctcGTCGACTGTTGCTTGCTGGTCGCAGACTCCCTGACCCCTCCCTCACCCCTCCCTAACCTCGGTGCCACCGGATTGCCCTTCTTTTCCTGTTGCCCAGCCCAGCCCTAGTGTCAGGGCGGGGGCCTGGAGCAGCCCGAGGCACTGCAGCAGAAGAGAGAAAAGACAACGACGACCCTCAGCTCGCCAGTCCGGTCGCTGGCTTCGCCGCCGCCATGGCAATGAGACAGACGCCGCTCACCTGCTCTGGCCACACGCGACCCGTGGTTGATTTGGCCTTCAGTGGCATCACGCCTTATGGGTATTTCTTAATCAGCGCTTGCAAAGATGGTAAACCTATGCTACGCCAGGGAGATACAGGAGACTGGATTGGAACATTTTTGGGTCATAAAGGTGCTGTTTGGGGTGCAACACTGAATAAGGATGCCACCAAAGCAGCTACAGCAGCTGCAGATTTCACAGCCAAAGTGTGGGATGCTGTCTCAGGAGATGAATTGATGACCCTGGCTCATAAACACATTGTCAAGACTGTGGATTTCACGCAGGATAGTAATTATTTGTTAACCGGGGGACAGGATAAACTGTTACGCATATATGACTTGAACAAACCTGAAGCAGAACCTAAGGAAATTAGTGGTCATACTTCTGGTATAAAAAAAGCTCTGTGGTGCAGTGAGGATAAACAGATTCTTTCTGCTGATGACAAAACTGTTCGACTTTGGGATCATGCTACTATGACAGAAGTGAAATCTCTAAATTTTAATATGTCTGTTAGTAGTATGGAATATATTCCTGAGGGAGAGATTTTGGTTATAACTTATGGACGATCTATTGCTTTTCATAGTGCAGTAAGTTTGGACCCAATTAAATCCTTTGAAGCTCCTGCAACCATCAATTCTGCATCTCTTCATCCTGAGAAAGAATTTCTTGTTGCAGGCGGTGAAGATTTTAAACTTTATAAGTATGATTATAATAGTGGAGAAGAATTAGAATCCTACAAGGGACACTTTGGTCCTATTCACTGTGTGAGATTTAGTCCTGATGGAGAACTCTATGCCAGTGGTTCAGAAGATGGAACATTGAGACTATGGCAAACTGTGGTAGGAAAAACGTATGGCCTTTGGAAATGTGTGCTTCCTGAAGAAGATAGTGGTGAGCTGGCAAAGCCAAAGATTGGTTTTCCAGAGACAACAGAAGAGGAGCTAGAAGAAATTGCTTCAGAGAATTCAGATTGCATCTTTCCTTCAGCTCCTGATGTTAAGGCCTGAGCGTCAATCATATGTGCAGTTAGTATACAACTGACTAAAACAAGCAAGCAGAGAAAAGCATCAGCCTTCCAGAGTTACTGTCTGCTTAAGGCAGAAACAGCAGTAAATAATGAGGAAAATGAATTAGCTCCAGTGCTGGAACAACTAACTAACTTGGTGTTACCTGTAAGTGAAAACTCAAGTGTCAGATGAAGGGAGGTGGAGTTATCCTCTTATAGTACAGTGGCCTGTTATCTTTTTAATGAATATATACAAGCCAACATCCAATTTCTATTATTACAATTAGGGTTCTTGTAGCTGTTTATGTTAATATGGAGAAGAAAACTATATTGGCTGATTTTTTCTGATCTTAAAGCAGAATGCCTTTTCTTTTTTTGCTTCAGTTGTAAAGAAGAGGGAATACATGATAAAGTAACTGGTTTGATTTCTCGTTCATTGTACACTGCCTCTGAACATCTAATTGTTTTTAGTTGTCTAAATAAAATGCCTCTAAAACAAAA

Publications

PMID - Link Title