Summary

Retrocopy Name	PIN4P3
Species	Homo sapiens
Coordinates (hg38)	chr2:40379382-40379726  UCSC
Coordinates (T2T)	chr2:40388388-40388732  UCSC
Coordinates (hg19)	chr2:40606522-40606866  UCSC
Strand	-
Parental Sequence	NM_006223.4
Parental seq. overlap	284 bp
Parental seq. overlap (%)	22.8%
Genomic Region	Intragenic (SLC8A1)
Retrocopy Summary	PIN4P3, located on chr2:40379382-40379726, is a retrocopy of the parental gene PIN4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	PIN4
Full Name	peptidylprolyl cis/trans isomerase, NIMA-interacting 4
Also known as	EPVH|PAR14|PAR17
Coordinate	chrX:72181676-72263964
Strand	+
Gene summary	This gene encodes a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. The encoded protein may play an additional role in the mitochondria. [provided by RefSeq, Dec 2009]

Homology

	Species	Scientific Name	Retrocopy
	Chimpanzee	Pan troglodytes	PIN4P3
	Bonobo	Pan paniscus	PIN4P3
	Gorilla	Gorilla gorilla	PIN4P3
	Orangutan	Pongo abelii	PIN4P3
	Gibbon	Nomascus leucogenys	PIN4P5
	Green monkey	Chlorocebus sabaeus	PIN4P1
	Crab-eating macaque	Macaca fascicularis	PIN4P7
	Rhesus	Macaca mulatta	PIN4P7
	Baboon	Papio anubis	PIN4P9
	Golden snub-nosed monkey	Rhinopithecus roxellana	PIN4P9
	Marmoset	Callithrix jacchus	PIN4P10
	Mouse lemur	Microcebus murinus	Without Homology
	Mouse	Mus musculus	Without Homology
	Rat	Rattus norvegicus	Without Homology
	Chinese hamster	Cricetulus griseus	Without Homology
	Rabbit	Oryctolagus cuniculus	Without Homology
	Pig	Sus scrofa	Without Homology
	Cow	Bos taurus	Without Homology
	Sheep	Ovis aries	Without Homology
	Dolphin	Tursiops truncatus	Without Homology
	Horse	Equus caballus	Without Homology
	Dog	Canis familiaris	Without Homology
	Panda	Ailuropoda melanoleuca	Without Homology
	Cat	Felis catus	Without Homology
	Pale spear-nosed bat	Phyllostomus discolor	Without Homology
	Velvety free-tailed bat	Molossus molossus	Without Homology
	Greater mouse-eared bat	Myotis myotis	Without Homology
	Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
	Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
	Egyptian rousette	Rousettus aegyptiacus	Without Homology
	Sloth	Choloepus didactylus	Without Homology
	Tasmanian Devil	Sarcophilus harrisii	Without Homology
	Opossum	Monodelphis domestica	Without Homology
	Platypus	Ornithorhynchus anatinus	Without Homology
	Chicken	Gallus gallus	Without Homology
	Turkey	Meleagris gallopavo	Without Homology
	Zebra Finch	Taeniopygia guttata	Without Homology
	Budgerigar	Melopsittacus undulatus	Without Homology
	Painted Turtle	Chrysemys picta	Without Homology
	Lizard	Anolis Carolinensis	Without Homology
	Frog	Xenopus tropicalis	Without Homology
	Zebrafish	Danio rerio	Without Homology
	Drosophila	Drosophila melanogaster	Without Homology

Expression

This retrocopy transcript is not present in the ARCHS4 database for expression quantificationThis retrocopy transcript is not present in the GTEx database for expression quantification.

Related Sequence

>PIN4P3

CAGTGCTGACATAAAGGCACAGGGTCCCAAAGGTGATGGTGATGCGGTAAACAGACACATTCTCTGCAGGGAAAAAAAAAAAGGCAAAATCATGAAGGCTATGGAAACATTAGTCTGGAATGAGATTCAGTGAAATGGCTGCACAACATAGTCAAGCTAAGGACAGGCAAGGGGGCGACTTCGGTTAGGTGACCAGAGGGTTCATGGGGGACACTTTTGAGAAGCACCATTTGCCATGCTTATAAGTGGGATGGATAAGCCTGTATTTATAGATCTCCTGGTTAAGACAAAATTTAAGTATCATCTTATTATGGTTGAAGGAAGAAAACAAAAATCATATGAAAA

>NM_006223.4

GGTTCAGCGTTCAACAACAAGCTTCCAAGATGCCGCCCAAAGGAAAAAGTGGTTCTGGAAAAGCGGGGAAAGGGGGAGCAGCCTCTGGGAGTGACAGTGCTGACAAGAAGGCTCAAGGTCCCAAAGGTGGTGGCAATGCAGTAAAGGTCAGACACATTCTATGTGAAAAACATGGCAAAATCATGGAAGCCATGGAAAAGTTAAAGTCTGGGATGAGATTCAATGAAGTGGCCGCACAGTATAGTGAAGATAAAGCCAGGCAAGGGGGTGACTTGGGTTGGATGACCAGAGGGTCCATGGTGGGACCATTTCAAGAAGCAGCATTTGCCTTGCCTGTAAGTGGGATGGATAAGCCTGTGTTTACAGACCCACCGGTTAAGACAAAATTTGGATATCATATTATTATGGTCGAAGGAAGAAAATAAAATCATATGAAAGACTGAATAAGTTTTATACATTTTGTTTCTTTAAAAGGTATTACATATTCTTTTGAGCTGGAGCTGCAAGGAAATACAAAAATTTTTAAAAAGAAAAGATATTGGATGCTCCTTGTATTCTGTGAAAGCTCTAAGTATGGGTTTGTAGGTGTAAGAGAGGGTGGGGCTAAGTGAATGTCAACTGTAGTAGGTATTCAGTCAGTCTTTCTCAAAGAGAAGTCAAGCAGACTCCCTTTAACCTGTATTCTCTTTCCTCCCAGAACTATATCTGACTCTCAGTCTGTCCCATAAATTAATTCAGAAACCATCTTCAGGGGAAGCAGATATCAACTCACACTATTCACACAACTGAAAATATTGGGCATCAAATAGATTAGTGTGTGAGAATCATAAAATAAGTTCCTAGACAACATTTGTTTTACATGTTAGTCAACTCTGATCTTCCAGGACAGGTGGTATTAGCTCCACTGTCTTAACATAGTACGTGGCACGTTATGCCTTTCAGTGTTAACTCCTTTCTTTTTAAATAAATGTTTATTGGAGGAAAAAAGCACTCAGTTGTTCCATGAGTTGTTTTGTACTAGACTAACCGAGTGCTGGTTAAAGGGAGGGATGTCAGCATAAAAATGTCATTCCCTCATCTTCAGTGTATGGGTTACATTAAGACTGTCCTTTCCAGGGCCAATGTTCTGTGCATCTAAATTTTTAAAATTTAAAATGCCATATTTATGACATATAAAAAAGTATAAAGATTACTAATATAAATACTATACTGCTTCAAAAATAAAACTTTGCCAACACA

Publications

PMID - Link	Title
No publications available for this retrocopy