Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RBISP3
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:47731337-47732092  UCSC
Coordinates (T2T) chr2:47736327-47737082  UCSC
Coordinates (hg19) chr2:47958476-47959231  UCSC
Strand -
Parental Sequence NM_001099673.3
Parental seq. overlap 342 bp
Parental seq. overlap (%) 37%
Genomic Region Intergenic
Retrocopy Summary RBISP3, located on chr2:47731337-47732092, is a retrocopy of the parental gene RBIS. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RBIS
Full Name ribosomal biogenesis factor
Also known as C8orf59
Coordinate chr8:85214048-85221079
Strand -
Gene summary Involved in ribosome biogenesis. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes C8H8orf59P1
Bonobo Pan paniscus RBISP1
Gorilla Gorilla gorilla RBISP1
Gibbon Nomascus leucogenys RBISP10
Green monkey Chlorocebus sabaeus C8H8orf59P8
Rhesus Macaca mulatta RBISP6
Baboon Papio anubis RBISP6
Golden snub-nosed monkey Rhinopithecus roxellana RBISP9
Orangutan Pongo abelii Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RBISP3
ACCACTAATCTTAAGAAGATAAACATTATGAATGATGAAAAAGCTAACAGAGTAAATAAAGCTTTTGTAAATGTACAAAAGGAACTTGCACATTTCTCAAAAGGCCTTTCTCTTGAACATCTACAGAAAGAATTGATTCCTCTGCAGTGTCATGAAAGCAAACCAGTTAATGTTGGTGAAGCTACAAAATTAATGGCTCAGTTGTAGTATAGTGGTGATGCATCTAATTCCACACAAAGACCAACAAATTACATGTTTTCAGATGGTGTCAACTGGAGCTGAAGAAGCTGCATGCAAGTATTAAATTCCTGACAAGGGCCAAGAACAAATTAAGAGGGCAGAAATCCAGGAATGTATTTCACATAGCCAGCGAAAAAAAACTTTGGGGCTAAAAACAAAGCAAAACCAGTTACCACTAATCttgtttt
>NM_001099673.3
CTAGACGCCGTACGTGCCAGATGGTGTTACCTGGAGCTTAAAAAGCTGCACGCAAGTGTTAAACTTCTGACAATGGCCAAGAACAAATTAAGAGGGCCGAAGTCCAGGAATGTATTTCACATAGCCAGCCAAAAAAACTTTAAGGCTAAAAACAAAGCAAAACCAGTTACCACTAATCTTAAGAAGATAAACATTATGAATGAGGAAAAAGTTAACAGAGTAAATAAAGCTTTTGTAAATGTACAAAAGGAACTTGCACATTTCGCAAAAAGCATTTCACTTGAACCTCTGCAGAAAGAACTGATTCCTCAGCAGCGTCATGAAAGCAAACCAGTTAATGTTGATGAAGCTACAAGATTAATGGCTCTGTTGTAATATACTGGTGATGCATCTAATTCTCCACAAAGACCAATAAATTGAATGTTTTATACAATTTTATTTTTAAAAATCTTGTTAATGTACAGGCATTGGCACATTTTAAAAACAAACTACATAAACAGATCTTTCCTATAACCTAGGAAAGTGGAATGTCAGAAGTCAACAAAATGTGATAAACTTAAAGTGCTAAAACAGAAGGCACTTCACAAAATCTGTTCACTGAAACAGTTATATATCCTCGTTTACATCCTTCACTTTACAAGTGGCAGTGAACGTCTGTTTGGATAGAAGGACATACAGAAATACAGGCAGTTTAGTGGCAGTAAAAATATAAGACAAGTAATGAGTCCTTGGCCAACTTGTTTTTGATGACCTGTAGTGTCCTTTAACTTTCCTCCTTAAGAAGAAAAAACAGAAGGATTCACAATTAGAAGAAAAGTTGAAATCCAGAATATAGTTACTTTTGGGAGTGGGGACGTTTGTGGATATTAAATCACTTATCCCCTAAA

Publications

PMID - Link Title