Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PIK3CDP1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:6494014-6496798  UCSC
Coordinates (hg19) chr2:6634146-6636930  UCSC
Strand -
Parental Sequence NM_005026.5
Parental seq. overlap 1939 bp
Parental seq. overlap (%) 34.7%
Genomic Region Intergenic
Retrocopy Summary PIK3CDP1, located on chr2:6494014-6496798, is a retrocopy of the parental gene PIK3CD. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PIK3CD
Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Also known as APDS|IMD14|IMD14A|IMD14B|P110DELTA|PI3K|ROCHIS|p110D
Coordinate chr1:9629889-9729114
Strand +
Gene summary Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PIK3CDP1
Bonobo Pan paniscus PIK3CDP1
Gorilla Gorilla gorilla PIK3CDP1
Gibbon Nomascus leucogenys PIK3CDP1
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PIK3CDP1
TCAGCCGTGGACTCAGGACCTGCCCGGTGATGCTGTAGGTCTCTCAAAGGTCTTCCAAAACTCCACTGAGCCAAAAGTAGCCGCCTGCTCAGCAGCTCAGGTGCCAGCTCTGTTCTGATTCACCAGGGGTCCATCAGCAGTCAGTGCCACCCACGGGGCACCTCCCTCGCCACATGCCTGTTCCTAGCAAGTGCTGAAACTCACCAGACCCCCTGCGTGTTTTGAAATGGAAAAGCCGTGCGCGCGCATATGTGTTATTTATTTAAGTGCACCTGTGTGCGCGGGCATGGGAGCGCACTTTGCAAGCCGCAGCATTTCTGGTAGTGTAGAGTCTTGTGTGCCTGGAGAGAAGAATATTTTCTATTTTTTAAAAATCATTTCATGTTTCTGTCTGAGGAAGGTGAGTTCAGTATCACTGATGTGGGTAGAGCCCAGCACTTTGTGAAACCTTGAAATGTCACTCTGCCGTTATCTGTGAGCCGCCTCTGAAAGCAGGTTTTAACAAAAGGGTGAGGCCAGATCTCTTCCAGAACCATCACCTTTGGGAACCTGCTGTGAGAGTGCTCAGGTAGCAGAAGTGTGAGAACGAGGGGGCGTGCTGGGATCTTTCTCTCTTGACTGTATTTAGTTTGAAATGGGGCAGGCTTAGCCTTAAGCCTCCAAAGGCCTGGATTTGAGCAGCTCACCTGCAGTCCCCACTCAACCCCAGCACCCTGCTGGCTGAAGTCTGCGTGGAGCAGTGCACCCTCATGGACTCCAAGATGAAGCCCCTGTGGATCATGTACAGCAATGAGGAGGCAGGCAGTGGTGGCAGGGTGAGCGTCAGCCTTAAGAGGGATGATGACCTCTGGCAGGACATGCTGACCATGCAGACGATCCGGCTCATGGACGTCCTGTGGAAGCAGCAGGGGCTGGACCTGAGGATGACCCCCTAAGGCTGCCTCCCCACTGGGGACCACACAGGCGTCGTTGAGGTGCTACTCCACCCAGACACCATCGCCAACATCCAACTCAACAACCGCAACATGGATGGAGGCAACGAAGAGTTCACCCTCTCCTGTGCTGGCTACTGTGTGGCCACGTACGTGCTGGGCATCGGTGATCGGCACAGCGACAACATCATGATCCGAGCGAGTGGGCAGCTGTTCCACATTGATTTTTGCCACTTTCTGGGGGAATTTCAAGACCACGTTTGGAATCAACCGTCAGCGTGTCCCATTCATCCTCACCTATGACTTTGTCCATGTGATTGAGCAGGGGAAGACTAATAATATGAGAAATTTGAAAGGTTCCGGGGCTACTGTGAAAGGGCCTAACACCATCCTGCGGCGCCACGGGCTTCTCTTCCTCCACCTCTTTGCCCTGATGCAGGCAGCAGGCCTGCCTGAGCTCAGCTGCTCCAAAGACATCCGGTATCTCAAGGACTCCCTGGCACCGGGGAAAACAGAGGAGGCGCTGAAGCACTTCCGAGTGAAGTTTAACGAAGCACTTCCGAGTGAAGTTTAACGAAGCACTTCCGAGTGAAGTTTAACGAAGCCCTCCGCGAGAGCTGGAAACCGAGTGAACTGGCTGGCCCACAACGTGTCCGAAGATAACCGGCAGTAGCGGCTCCTCCCTGCCCCGGCCCGAGAGGAGGCAGCCGCGAGTCGTGGGGACCAGGCACGTTGGTGGTCCTAAAGGGGCTGAAGAGCCTGACCTGCACCTCACGGGAAAGAACCTACACAGCCACCTTTTTTTTTTTTTACACTAGTTATTTCTGTATGACTTGAAATGTTTAAGGAGCTAAACAGCCATAAACGGAAATGCCTCCTTCGCGCAGCGGCGGTGCTGGGCTGCTCGAGGCTGCACCTTGCTCTTGGCTGAGGAGGGTCACCCCAAGTCTTCCAGCCGGTGGATCTGGGCCCAGCAAAGACTGTTCTGCTCCCCGGGGACCTTCTTCCCAGGCCAGACTGCCTGGGTCCAAGCACTTGGCGGTCACCTGGTGCCTACTGTCCGACAGGACGCCCCGATCCTCATCGGCTCGAGCGACCCACCTTGTGCATCCTCTCTAGACTGAGTTCTGGCAGCTCCCCGAGGGGGCCAGGGTACCCTCTAGATTCAGGGATGCTTGCTCTCCACTTTTCAAGTGGGTCTTGGGTACAAGAATTCCCTCGCCTCTGTCTATTGTAAAGTGATTTTGTTTGCAGGTAAGAAAATAATAGACGACTCACCAAACCTCTACGGCTGGAGAGATCGGGCCCAGCCCCATAAAGCAGTATATGTGCTGGTCCTCAGGGCATGTTAAAGAGACCTGGGCCTCATGGAGCTCACCCTGGTCATGCATGAAGCTGGTCAGAGGCGAACACTGCCATTATCTCAAt
>NM_005026.5
ACTCGCGCCCAGCGCAGTCGCTCCGAGCGGCCGCGAGCAGAGCCGCCCAGCCCTGCCAGCTGCGCCGGGACGATAAGGAGTCAGGCCAGGGCGGGATGACACTCATTGATTCTAAAGCATCTTTAATCTGCCAGGCGGAGGGGGCTTTGCTGGTCTTTCTTGGACTATTCCAGAGAGGACAACTGTCATCTGGGAAGTAACAACGCAGGATGCCCCCTGGGGTGGACTGCCCCATGGAATTCTGGACCAAGGAGGAGAATCAGAGCGTTGTGGTTGACTTCCTGCTGCCCACAGGGGTCTACCTGAACTTCCCTGTGTCCCGCAATGCCAACCTCAGCACCATCAAGCAGCTGCTGTGGCACCGCGCCCAGTATGAGCCGCTCTTCCACATGCTCAGTGGCCCCGAGGCCTATGTGTTCACCTGCATCAACCAGACAGCGGAGCAGCAAGAGCTGGAGGACGAGCAACGGCGTCTGTGTGACGTGCAGCCCTTCCTGCCCGTCCTGCGCCTGGTGGCCCGTGAGGGCGACCGCGTGAAGAAGCTCATCAACTCACAGATCAGCCTCCTCATCGGCAAAGGCCTCCACGAGTTTGACTCCTTGTGCGACCCAGAAGTGAACGACTTTCGCGCCAAGATGTGCCAATTCTGCGAGGAGGCGGCCGCCCGCCGGCAGCAGCTGGGCTGGGAGGCCTGGCTGCAGTACAGTTTCCCCCTGCAGCTGGAGCCCTCGGCTCAAACCTGGGGGCCTGGTACCCTGCGGCTCCCGAACCGGGCCCTTCTGGTCAACGTTAAGTTTGAGGGCAGCGAGGAGAGCTTCACCTTCCAGGTGTCCACCAAGGACGTGCCGCTGGCGCTGATGGCCTGTGCCCTGCGGAAGAAGGCCACAGTGTTCCGGCAGCCGCTGGTGGAGCAGCCGGAAGACTACACGCTGCAGGTGAACGGCAGGCATGAGTACCTGTATGGCAGCTACCCGCTCTGCCAGTTCCAGTACATCTGCAGCTGCCTGCACAGTGGGTTGACCCCTCACCTGACCATGGTCCATTCCTCCTCCATCCTCGCCATGCGGGATGAGCAGAGCAACCCTGCCCCCCAGGTCCAGAAACCGCGTGCCAAACCACCTCCCATTCCTGCGAAGAAGCCTTCCTCTGTGTCCCTGTGGTCCCTGGAGCAGCCGTTCCGCATCGAGCTCATCCAGGGCAGCAAAGTGAACGCCGACGAGCGGATGAAGCTGGTGGTGCAGGCCGGGCTTTTCCACGGCAACGAGATGCTGTGCAAGACGGTGTCCAGCTCGGAGGTGAGCGTGTGCTCGGAGCCCGTGTGGAAGCAGCGGCTGGAGTTCGACATCAACATCTGCGACCTGCCCCGCATGGCCCGTCTCTGCTTTGCGCTGTACGCCGTGATCGAGAAAGCCAAGAAGGCTCGCTCCACCAAGAAGAAGTCCAAGAAGGCGGACTGCCCCATTGCCTGGGCCAACCTCATGCTGTTTGACTACAAGGACCAGCTTAAGACCGGGGAACGCTGCCTCTACATGTGGCCCTCCGTCCCAGATGAGAAGGGCGAGCTGCTGAACCCCACGGGCACTGTGCGCAGTAACCCCAACACGGATAGCGCCGCTGCCCTGCTCATCTGCCTGCCCGAGGTGGCCCCGCACCCCGTGTACTACCCCGCCCTGGAGAAGATCTTGGAGCTGGGGCGACACAGCGAGTGTGTGCATGTCACCGAGGAGGAGCAGCTGCAGCTGCGGGAAATCCTGGAGCGGCGGGGGTCTGGGGAGCTGTATGAGCACGAGAAGGACCTGGTGTGGAAGCTGCGGCATGAAGTCCAGGAGCACTTCCCGGAGGCGCTAGCCCGGCTGCTGCTGGTCACCAAGTGGAACAAGCATGAGGATGTGGCCCAGATGCTCTACCTGCTGTGCTCCTGGCCGGAGCTGCCCGTCCTGAGCGCCCTGGAGCTGCTAGACTTCAGCTTCCCCGATTGCCACGTAGGCTCCTTCGCCATCAAGTCGCTGCGGAAACTGACGGACGATGAGCTGTTCCAGTACCTGCTGCAGCTGGTGCAGGTGCTCAAGTACGAGTCCTACCTGGACTGCGAGCTGACCAAATTCCTGCTGGACCGGGCCCTGGCCAACCGCAAGATCGGCCACTTCCTTTTCTGGCACCTCCGCTCCGAGATGCACGTGCCGTCGGTGGCCCTGCGCTTCGGCCTCATCCTGGAGGCCTACTGCAGGGGCAGCACCCACCACATGAAGGTGCTGATGAAGCAGGGGGAAGCACTGAGCAAACTGAAGGCCCTGAATGACTTCGTCAAGCTGAGCTCTCAGAAGACCCCCAAGCCCCAGACCAAGGAGCTGATGCACTTGTGCATGCGGCAGGAGGCCTACCTAGAGGCCCTCTCCCACCTGCAGTCCCCACTCGACCCCAGCACCCTGCTGGCTGAAGTCTGCGTGGAGCAGTGCACCTTCATGGACTCCAAGATGAAGCCCCTGTGGATCATGTACAGCAACGAGGAGGCAGGCAGCGGCGGCAGCGTGGGCATCATCTTTAAGAACGGGGATGACCTCCGGCAGGACATGCTGACCCTGCAGATGATCCAGCTCATGGACGTCCTGTGGAAGCAGGAGGGGCTGGACCTGAGGATGACCCCCTATGGCTGCCTCCCCACCGGGGACCGCACAGGCCTCATTGAGGTGGTACTCCGTTCAGACACCATCGCCAACATCCAACTCAACAAGAGCAACATGGCAGCCACAGCCGCCTTCAACAAGGATGCCCTGCTCAACTGGCTGAAGTCCAAGAACCCGGGGGAGGCCCTGGATCGAGCCATTGAGGAGTTCACCCTCTCCTGTGCTGGCTATTGTGTGGCCACATATGTGCTGGGCATTGGCGATCGGCACAGCGACAACATCATGATCCGAGAGAGTGGGCAGCTGTTCCACATTGATTTTGGCCACTTTCTGGGGAATTTCAAGACCAAGTTTGGAATCAACCGCGAGCGTGTCCCATTCATCCTCACCTACGACTTTGTCCATGTGATTCAGCAGGGGAAGACTAATAATAGTGAGAAATTTGAACGGTTCCGGGGCTACTGTGAAAGGGCCTACACCATCCTGCGGCGCCACGGGCTTCTCTTCCTCCACCTCTTTGCCCTGATGCGGGCGGCAGGCCTGCCTGAGCTCAGCTGCTCCAAAGACATCCAGTATCTCAAGGACTCCCTGGCACTGGGGAAAACAGAGGAGGAGGCACTGAAGCACTTCCGAGTGAAGTTTAACGAAGCCCTCCGTGAGAGCTGGAAAACCAAAGTGAACTGGCTGGCCCACAACGTGTCCAAAGACAACAGGCAGTAGTGGCTCCTCCCAGCCCTGGGCCCAAGAGGAGGCGGCTGCGGGTCGTGGGGACCAAGCACATTGGTCCTAAAGGGGCTGAAGAGCCTGAACTGCACCTAACGGGAAAGAACCGACATGGCTGCCTTTTGTTTACACTGGTTATTTATTTATGACTTGAAATAGTTTAAGGAGCTAAACAGCCATAAACGGAAACGCCTCCTTCATGCAGCGGCGGTGCTGGGCCCCCCGAGGCTGCACCTGGCTCTCGGCTGAGGATTGTCACCCCAAGTCTTCCAGCTGGTGGATCTGGGCCCAGCAAAGACTGTTCTCCTCCCGAGGGAACCTTCTTCCCAGgcctcccgccagactgcctgggtcctggcgcctggcgGTCACCTGGTGCCTACTGTCCGACAGGATGCCTTGATCCTCGTGCGACCCACCCTGTGTATCCTCCCTAGACTGAGTTCTGGCAGCTCCCCGAGGCAGCCGGGGTACCCTCTAGATTCAGGGATGCTTGCTCTCCACTTTTCAAGTGGGTCTTGGGTACGAGAATTCCCTCATCTTTCTCTACTGTAAAGTGATTTTGTTTGCAGGTAAGAAAATAATAGATGACTCACCACACCTCTACGGCTGGGGAGATCAGGCCCAGCCCCATAAAGGAGAATCTACGCTGGTCCTCAGGACGTGTTAAAGAGATCTGGGCCTCATGTAGCTCACCCCGGTCACGCATGAAGGCAAAAGCAGGTCAGAAGCGAATACTCTGCCATTATCTCAAAAAtcttttttttttttttgagatggggtcttcctctgttgcccaggctggagtgcagtggtgcaatcttggctcactgtaacctccgcctcccaggttcaagtgattcttctgcctcagcctcctgagtagctgggattacaggtgtgcaccaccgtacccagctaatttttgtattttagtagagacgggggtttcaccatgttggctgggctggtctcgaactcctgacctcaggtgatccacccgcctgagcctcccaaagtgctgggattacaggcatgagccaccgcgcccggccCACTCTGCCATTGTCTAAGCCACCTCTGAAAGCAGGTTTTAACAAAAGGATGAGGCCAGAACTCTTCCAGAACCATCACCTTTGGGAACCTGCTGTGAGAGTGCTGAGGTACCAGAAGTGTGAGAACGAGGGGGCGTGCTGGGATCTTTCTCTCTGACTATACTTAGTTTGAAATGGTGCAGGCTTAGTCTTAAGCCTCCAAAGGCCTGGATTTGAGCAGCTttagaaatgcaggttctagggcttctcccagccttcagaagccaactaactctgcagatggggctaggactgtgggcttttagcagcccacaggtgatcctaaCATATCAGGCCATGGACTCAGGACCTGCCCGGTGATGCTGTTGATTTCTCAAAGGTCTTCCAAAACTCAACAGAGCCAGAAGTAGCCGCCCGCTCAGCGGCTCAGGTGCCAGCTCTGTTCTGATTCACCAGGGGTCCGTCAGTAGTCATTGCCACCCGCGGGGCACCTCCCTGGCCACACGCCTGTTCCCAGCAAGTGCTGAAACTCACTAGACCGTCTGCCTGTTTCGAAATGGGGAAAGCCGTGCGTGCGCGTTATTTATTTAAGTGCGCCTGTGTGCGCGGGTGTGGGAGCACACTTTGCAAAGCCACAGCGTTTCTGGTTTTGGGTGTACAGTCTTGTGTGCCTGGCGAGAAGAATATTTTCTATTTTTTTAAGTCATTTCATGTTTCTGTCTGGGGAAGGCAAGTTAGTTAAGTATCACTGATGTGGGTTGAGACCAGCACTCTGTGAAACCTTGAAATGAGAAGTAAAGGCAGATGAAAAGAAAGAAAAAGCCTTTTTATGTTCTTTTATGTTCTCGGCTCAAAAAGAAACAAGGGAGTGTAGGTTTAAAACCAAAACAGGAGAGAAGACAAACCCCGCTCCGGCTGGAGTTAGTTAGAACCAGAACTTTATTGTAGCGGATACACTTTCTGACCTATCATGAGTATACACATCTGCGAAGGGAAACCGCGCGGCGACA

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