Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name WBP1P1
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:86929719-86930898  UCSC
Coordinates (T2T) chr2:86931627-86932806  UCSC
Coordinates (hg19) chr2:87156842-87158021  UCSC
Strand -
Parental Sequence NM_012477.4
Parental seq. overlap 1134 bp
Parental seq. overlap (%) 94.3%
Genomic Region Intragenic (RGPD1)
Retrocopy Summary WBP1P1, located on chr2:86929719-86930898, is a retrocopy of the parental gene WBP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name WBP1
Full Name WW domain binding protein 1
Also known as WBP-1
Coordinate chr2:74458438-74460881
Strand +
Gene summary The globular WW domain, named for the conserved tryptophan residues in the protein motif present in various structural and regulatory proteins, is known to play a role in the mediation of protein-protein interactions. This gene encodes a ligand of the WW domain of the Yes kinase-associated protein. Readthrough transcription of the neighboring upstream gene, which encodes INO80 complex subunit B, into this gene generates a non-coding transcript. [provided by RefSeq, Feb 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>WBP1P1
GGATGGAAGCTCCGGCCGCGGAGTGATGGTGGCCTCAGCGAAGATGGGCCGGGCAGGGACCATGGCAGTGGCAGCAGAGGTGGCAGGGGCGGGGCGGCTGGCGGTAGAGGAGGCTGTGGTCCTCAGGGGGCTGTAGGTGGAGGTATGGCTCGGGCCAGCAGCGGGAACGGCAGCGAGGAGGCCTGGGGGGCACTTCGGGCGCCGCAACAGCAGCTTCGAGAGCTGTGCCCAGGAGTGAACAACCAGCCCTACCTCTGTGAGAGTGTTCACTGCTGCGGGGAGACTGGCTGCTGCACCTACTACTATGAGCTCTGGTGGTTCTGGCTGCTCTGGACTGTCCTCATCCTCTTTAGCTGCTGTTGGGCCTTCCGCCACCGACGAGCTAAACTCAGGCTGCAACAACAGCAGCGGCAGCGTGAAATCAACTTGTTGGCTTATCATGGGGCATGCCATGGGGCTGGTCCTTTCCCTACCGGTTCACTGCTTGACCTTCGCCTCCTCAGCACCTTCAAGCCCCCAGCCTACGAGGATGTGGTTCACCGCCCAGGCACCACCCCCCGCCCCCCGCCTCCGCGCCTTATACTGTCGCCCCAGGCCGCCCCTTGACTGCTTCCAGTGAACAAACCTGCTGTTCCTCCTCATCCAGCTGCCCTGCCCATTTTGAAGGAACAAATGTGGAAGGTGTTTCCTCCCACCAGAGTGCCCTCCCTCATCAGGAGGGTGAGTCTGGGGCAGGGGTGACCCCTGCCCCCACACCCCCCTCCTGCCGCTATCGCCGTTTAACTGGCGACTCCGGTATTAAGCTCTGCCCTTGTCCTGCCTCCGGTGAGGCTGAGCCAGTCAAGGAGGTGAGGGTTAGTGCCACCCTGCCAGATCTGGAGGACTACTCCCCGTGTGCACTGCCCCCAGATTCTGTACCGCAGGTCTTTCCCATGGGGCTGTCTTCCAGTGAAGGGGACATCCCATAAGTAGTTTTGAGAGGGTGGATGGGTTACTTGCCCACCAGAAACAGCCCTAGTCCCAACTCCTTGCGTTCCTTTTGGCCCCTCCCTGCCTACCTAGAATCTGCCTGAAAGGGCTGGAGCCCTGAGGAGAGGGGCAGTATTGGGGGACTGTGCTAGCTTTACCCCCGCAAGACATACACAGGAGCCTTTGATCTCATTAAAGAGACGTGAACCAG
>NM_012477.4
CTAGTTGGTGGAGTTCTGCCCGGATGGAAGCTCCGGCCGCGGAGTGATGGTGGCCTCAGCGAAGATGGGCCGGGCAGGGACCATGGCGGTGGCAGCAGAGGTGGCAGGGGCGGGGCGGCTGGCGGTAGAGGAGGCTGTGGTCCTCAGGGGGCTGTAGGTGGAGGTATGGCTCGGGCCAGCAGCGGGAACGGCAGCGAGGAGGCCTGGGGGGCACTTCGGGCGCCGCAACAGCAGCTTCGAGAGCTGTGCCCAGGAGTGAACAACCAGCCCTACCTCTGTGAGAGTGGTCACTGCTGCGGGGAGACTGGCTGCTGCACCTACTACTATGAGCTCTGGTGGTTCTGGCTGCTCTGGACTGTCCTCATCCTCTTTAGCTGCTGTTGCGCCTTCCGCCACCGACGAGCTAAACTCAGGCTGCAACAACAGCAGCGGCAGCGTGAAATCAACTTGTTGGCCTATCATGGGGCATGCCATGGGGCTGGTCCTTTCCCTACCGGTTCACTGCTTGACCTTCGCTTCCTCAGCACCTTCAAGCCCCCAGCCTACGAGGATGTGGTTCACCGCCCAGGCACACCACCCCCCCCTTATACTGTGGCCCCAGGCCGCCCCTTGACTGCTTCCAGTGAACAAACCTGCTGTTCCTCCTCATCCAGCTGCCCTGCCCACTTTGAAGGAACAAATGTGGAAGGTGTTTCCTCCCACCAGAGTGCCCCCCCTCATCAGGAGGGTGAGCCCGGGGCAGGGGTGACCCCTGCCTCCACACCCCCCTCCTGCCGCTATCGCCGTTTAACTGGCGACTCCGGTATTGAGCTCTGCCCTTGTCCTGCCTCCGGTGAGGGTGAGCCAGTCAAGGAGGTGAGGGTTAGTGCCACCCTGCCAGATCTGGAGGACTACTCCCCGTGTGCACTACCCCCAGAGTCTGTACCGCAGATCTTTCCCATGGGGCTGTCTTCCAGTGAAGGGGACATCCCATAAGTAGTTTTGAGAGGGTGGATGGGTTACTTGCCCACCAGAAACAGCCCTAGTCCCAACTCCTTGCGTTCCTTTGGCCCCTCCCTGCCTACCTAGAATCTGCCTGAAAGGGCTGGAGAGGGGCAGTATTGGGGGACTGTGCTAGCTTTACCCCCGCAGGACATACACAGGAGCCTTTGATCTCATTAAAGAGATGTGAACCA

Publications

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