Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NIP7P2
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:132401219-132402002  UCSC
Coordinates (T2T) chr3:135145697-135146480  UCSC
Coordinates (hg19) chr3:132120063-132120846  UCSC
Strand +
Parental Sequence NM_016101.5
Parental seq. overlap 730 bp
Parental seq. overlap (%) 35.5%
Genomic Region Intergenic
Retrocopy Summary NIP7P2, located on chr3:132401219-132402002, is a retrocopy of the parental gene NIP7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NIP7
Full Name nucleolar pre-rRNA processing protein NIP7
Also known as CGI-37|HSPC031|KD93
Coordinate chr16:69339772-69343106
Strand +
Gene summary Enables RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NIP7P1
Bonobo Pan paniscus NIP7P1
Gorilla Gorilla gorilla NIP7P1
Orangutan Pongo abelii NIP7P1
Gibbon Nomascus leucogenys NIP7P3
Green monkey Chlorocebus sabaeus NIP7P2
Crab-eating macaque Macaca fascicularis NIP7P1
Rhesus Macaca mulatta NIP7P1
Baboon Papio anubis NIP7P1
Golden snub-nosed monkey Rhinopithecus roxellana NIP7P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NIP7P2
ACACGAGGATCTGGTGTTCCAACCCAGCAGGAAAATGCGGCCTTTGACTGAAGAGGAGACCCATGTCATGTTTGAGAAGATTGTGAAGTACATCAGGGAGAATCTTCAGCTGCTGCTGGACCGGCCTGACCGCACCTACTGTTTCTGGCTGCACAACGACCGGGTGGACTATGTGAGTGAGAAGATTGTGAAGCTGGATGCCAATATCTCCGGGGACAAGCTGGTGTCACTGGGGACCTGCTTCGGAAAAGTCACTAAGACCCACAAGTTTCGGTTCACGTCACAGCCCTGAATTACCTTGCACCTTATGCCGAGTATAAAGTGTGGATAAAGCGTGGTGCAGAGCAGTCCTTCCTCTATGGAAACCATGTGTTGAAATATAGTCTGGGTCGAATCACCGAAAATAGTTCTCAGTACCAGGGGAGTGGTGGTGTACTCCATGGCAGACATCCCTTTGGGTTTTGGGGTGGCAGCAAAATCTACACAAGACTGCAGAAAAGTAGACCCCATGGCGATTGTGGTACTTCATCAAGCAGACATTGGGGAATATGCACAGCATGAAGAGACGTTGACTTAAAACGAAGTCATTGCAAGGACAGCTGTGTGGAAGGGCCGAGTTTTGTTTCCTGTGTTTGTGTAGACTCCACCATCATGTTGAATTTTGTCAACACTATGGCCTCTTCAGGGACATCTTAGTTTACTGTACTCTCTATCACTGACAGATGCAGGCTGGATTCTTATTATATACAGAGATGGCTCAAAAATGGGGTTTCAGATCTTTGTG
>NM_016101.5
GACTTCCGTTTCCAGTTACCAAGGCACGAGGATCCGGTGTTCCAACCCAGGGGGAAAAATGCGGCCTTTGACTGAAGAGGAGACCCGTGTCATGTTTGAGAAGATAGCGAAATACATTGGGGAGAATCTTCAACTGCTGGTGGACCGGCCCGATGGCACCTACTGTTTCCGTCTGCACAACGACCGGGTGTACTATGTGAGTGAGAAGATTATGAAGCTGGCCGCCAATATTTCCGGGGACAAGCTGGTGTCGCTGGGGACCTGCTTTGGAAAATTCACTAAAACCCACAAGTTTCGGTTGCACGTCACAGCTCTGGATTACCTTGCACCTTATGCCAAGTATAAAGTTTGGATAAAGCCTGGTGCAGAGCAGTCCTTCCTGTATGGGAACCATGTGTTGAAATCTGGTCTGGGTCGAATCACTGAAAATACTTCTCAGTACCAGGGCGTGGTGGTGTACTCCATGGCAGACATCCCTTTGGGTTTTGGGGTGGCAGCCAAATCTACACAAGACTGCAGAAAAGTAGACCCCATGGCGATTGTGGTATTTCATCAAGCAGACATTGGGGAATATGTGCGGCATGAAGAGACGTTGACTTAAAACGAAGCCATTCCAAGGACAGACGGCTGTATGGAAAGGCCGAGCTTTGTTTCCTGTGTTTGTGTGGACTCCACCATCATGTTGAATTTTGTCAACACTCTGGCCTCTTCAGGGACTTCTTATTTACTGTACTCTCTATCACTGACAAATGCAGGCTGGATTCTTATTATATACAGAGATGGCTCAAAAATGGGGTTTCAGATCTTTGTGACGAAATAGAATACTGTTTCATATTTGAATCAGAGGGCTTCTTGTTCTGAGAAATAGGTTCAAAATCATTGGAACCAGGAACAAGAATAGCTTATTGTTATCTGTGATAACACTGTTTTCTAAACACAAGGATTTTCTTTTTTATTAATATGCAACATAGACATTGCCATAACAGAATAATAAACCACATGTGGGGTTTTAAAAATGAAATTTGGCTAATAGGAGCAATTCAGCTATTTTTCTATACAGTAATTGGTGTGTGGTATAGAagaaaaacgggttcaaaccccacttctgccacctaccagctatatggccttgaatgagtcattcagctttaataaggttcattttcttctgtttaaaaAGACACAAAACTTGAAAATCAGCTTTGGCCATCTACCTGAGAATTAGAAAGTCTGATTTTTGGAATTAGAAATCATGATTGTAggctgggcacagtggctcgcgcctgtaatcccagcactttgggaggccaaggcggacggatcacttgaggttaggagtttgagaccagcctggccaacatggtgaaaccccatctctactaaaaaaaaaaaaaaaattaggtgtggtgacacatggctgtggtcctagttacttgggaggctgaggcaggagaatggcttgaactggggaagcagagcttgcagtgagccaagatggtgccattgcactccagcctgggcgtgacagagtgagactccatctGATTGTAAAGCATCTAGTACAGTGTACAGTGCCTTGGAAATGATAGGTATGGAATAAATGGTAATTATTTTTATATTATATATATTATGTATTCCTGTTATTAAGTGTAGAGTTTTATGAGTATAATTTGATTTTATTACCTTCTTTTTTACAAGCTGTTTTCTCAGTATTTTTCTTGGATGGGATGACGCTAGGCTGGAAAGTTTTTTTCATCACTATGATTTTATAAAACAATTTTTTCTATGAACCTTTACTTACTTGACTGGATTGGACTAAAAGCACTGATCAGAGGCCACGACATAAAAATTCAGTCCCTTTGTCCTTCCCCGTGCCTCCCAAAGTTACTTTAAGATCCTTAGAATATTTCTTTAAATATTTTATAGACAAAAAATTTAAAGACTATCTGTATTGCAAAATTAAACTATTTCTTTAATGAATATATTGCTTATTTTAAGTTCCAAAGGTGAAGTCTTTAAGAATAAAACATTACCAACTCCTGCTTTTATATGTAA

Publications

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