Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DONSONP1
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr21). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:136055186-136055764  UCSC
Coordinates (T2T) chr3:138800994-138801572  UCSC
Coordinates (hg19) chr3:135774028-135774606  UCSC
Strand +
Parental Sequence NM_017613.4
Parental seq. overlap 546 bp
Parental seq. overlap (%) 21.8%
Genomic Region Intragenic (PPP2R3A)
Retrocopy Summary DONSONP1, located on chr3:136055186-136055764, is a retrocopy of the parental gene DONSON. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DONSON
Full Name DNA replication fork stabilization factor DONSON
Also known as B17|C21orf60|MIMIS|MISSLA
Coordinate chr21:33577551-33588684
Strand -
Gene summary This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DONSONP1
Bonobo Pan paniscus DONSONP1
Gorilla Gorilla gorilla DONSONP1
Orangutan Pongo abelii DONSONP1
Gibbon Nomascus leucogenys DONSONP1
Green monkey Chlorocebus sabaeus DONSONP1
Crab-eating macaque Macaca fascicularis DONSONP1
Rhesus Macaca mulatta DONSONP1
Baboon Papio anubis DONSONP1
Golden snub-nosed monkey Rhinopithecus roxellana DONSONP1
Marmoset Callithrix jacchus DONSONP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DONSONP1
AGAAGAGATGACTGTGCAAGATAAAATTAAAAAGCCAGACATACTTTCTATCAAGCTGCGTAAAAAGAAACATGAAGTACAAATGGATCACAGACCTGAGTCTGTTGTGTTGGTGAAAGGAATCAACATCTTTACATTGCTCAATTTTTTGATCAACTCTAAGAGTTTAGTTGCTACCTCAGGTCCACAGGTAGGACTTCCTCTGACCCTCTTATCCCCTGTTGCTCTCCGAGGTGCCATAATGCAAATGCTTAAGGCACAAAGTGTAAATGTGAAGACACAGCTCTTTCTGGATACAGAGACCAGTTTAGTTTGGAGATTACAGGTTCTATCGTGCCTCATTCTCTGCATTCACTGACCATGCTGCTCAAATCTTCACAGAGCGGGTCTTTCTCTGCAGTACTGTATCCACACGAGCCAACTGCTGTATTTAACACCTGCCTGCCAATGGACAAAGTACTTGATACAGAGGTTGTTCATAAGGAGCTTACTAACTGTGGTTTGCACCCTAAGACTCTGGAGCAACTTAGAGAAATACCACTACTTGGGAAATCATCTTTATGGAATGTGGTGATGAGA
>NM_017613.4
AAGTCTCTGTAGGGCGGCCGGCTACCCTCAGCCGCCGCGCGTCATGGCCCTTTCGGTGCCCGGCTACTCACCGGGCTTCCGAAAGCCGCCCGAGGTAGTGCGGCTCCGACGGAAAAGGGCCCGGAGCCGTGGAGCTGCCGCCTCCCCGCCCCGTGAGCTGACGGAGCCGGCGGCCCGCCGAGCCGCCCTGGTGGCGGGGCTGCCTCTTCGCCCTTTCCCTgctgcggggggcagaggcggtggcagcggcggcggcccggccgctgcTCGGAGGAACCCCTTCGCCCGCCTGGACAACCGACCGCGGGTCGCCGCGGAGCCCCCCGACGGGCCGGCCCGCGAGCAGCCGGAGGCCCCGGTCCCGTTTTTAGATTCTAATCAAGAAAATGATTTGCTATGGGAAGAGAAGTTTCCTGAAAGAACAACTGTTACTGAATTACCTCAGACTTCACATGTATCATTCTCCGAGCCTGATATTCCGTCCTCAAAAAGTACTGAGTTACCTGTGGACTGGAGTATTAAAACGCGACTCCTTTTCACCTCTTCTCAACCCTTTACCTGGGCAGATCATTTGAAAGCACAGGAAGAAGCTCAAGGTCTTGTCCAGCATTGTAGGGCAACAGAAGTTACTTTGCCTAAAAGTATACAGGATCCCAAACTCTCCTCTGAGCTCCGTTGTACCTTCCAGCAGAGCCTTATCTATTGGCTCCACCCTGCTTTGTCTTGGCTACCACTGTTCCCTCGTATTGGAGCTGATAGAAAAATGGCTGGAAAGACAAGTCCTTGGTCAAATGATGCAACCCTGCAGCATGTTTTAATGAGTGACTGGTCTGTGAGCTTTACTTCTCTATATAATTTGCTGAAGACAAAACTTTGCCCCTATTTCTACGTTTGTACCTATCAGTTTACTGTCCTGTTCCGAGCAGCAGGATTAGCTGGAAGTGACTTAATCACAGCTCTCATATCTCCAACAACTCGAGGTTTAAGAGAAGCTATGAGAAATGAAGGTATTGAATTTTCTCTGCCTTTAATAAAAGAAAGTGGCCATAAGAAGGAGACAGCATCTGGAACAAGCTTGGGATATGGGGAGGAGCAAGCCATCAGTGATGAGGATGAAGAGGAAAGTTTTTCCTGGCTGGAAGAGATGGGTGTGCAAGATAAAATTAAAAAGCCAGACATACTTTCTATCAAGCTGCGTAAAGAGAAACATGAAGTACAAATGGATCACAGACCTGAATCTGTTGTGTTGGTAAAAGGAATCAACACCTTTACATTGCTCAATTTTTTGATTAACTCTAAGAGTTTAGTTGCTACCTCAGGTCCACAGGCAGGACTTCCTCCAACCCTCTTGTCCCCTGTTGCTTTCCGAGGTGCCACAATGCAAATGCTTAAGGCACGGAGTGTGAATGTGAAGACACAAGCTCTTTCTGGATACAGAGACCAATTTAGTTTGGAGATTACAGGTCCTATCATGCCTCATTCTCTGCATTCACTGACCATGCTGCTCAAATCTTCACAGAGTGGATCTTTCTCTGCAGTACTGTATCCACACGAGCCAACTGCTGTATTTAACATCTGCCTGCAAATGGACAAAGTACTTGATATGGAGGTTGTTCATAAGGAGCTTACTAACTGTGGTTTGCACCCTAACACTCTGGAGCAACTTAGTCAAATACCGTTACTTGGGAAATCATCTTTACGGAATGTGGTGCTGAGAGACTACATTTATAATTGGAGATCCTGAACACCAAAGTAAGCCTAAAAGGAATCTTTGAGGAAAAAAGCCTTCTAGCAAGGAAATTCAAGATTCTTGAAGTTGAAGGAATATACTGAAATGTTTATAAACATAACTTTTACTACAGTAGCATCTAAGGTTTTAAATGTGTTTTACTATTTTCAGATTAGATTTTTAGATATAAAGATGAAAAACTCAGATAACTCAAATGAGATATCTATATCCCTACAACCTAATTGTATATTGAGCAGAAACTGAATTAATATGCTTCCTTGCAAATGGGAAATCACATAGCAGTTACCCCATGGCATTGTGACTAATGGCATCAGGGCAAAAATATGTTACTTTACGATTTACCTGTTAGCAGGTTCTTGTTTCATAAAGGTAGAAAATAAATACAGACAACATCTACTGAGCTAGTTGATTGGTGATGCTTCTACCTTAATATCTTTCCTACTGATTTATAATTCCTTTATTTTCACATATACTAAAACTTTTTAAATGCATGTTAATTCAGATAAAAAGGCATTTTGTATTCCACATAGAATAGTGTTAAGAATTGTGAAGTACACTGAGCTGTCACGGCAAAGTAGTATTTAATGTGCTTATAGGGgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtAGGGGGGGACTGTATAATTCACATTTTTAAAATAAAAGTGCTTAAAAATCAAAA

Publications

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