Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name WDR70P5
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:149462074-149464831  UCSC
Coordinates (T2T) chr3:152213272-152216029  UCSC
Coordinates (hg19) chr3:149179861-149182618  UCSC
Strand -
Parental Sequence NM_001345998.2
Parental seq. overlap 941 bp
Parental seq. overlap (%) 31.8%
Genomic Region Intergenic
Retrocopy Summary WDR70P5, located on chr3:149462074-149464831, is a retrocopy of the parental gene WDR70. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name WDR70
Full Name WD repeat domain 70
Also known as -
Coordinate chr5:37379318-37753435
Strand +
Gene summary Enables enzyme binding activity. Predicted to be involved in regulation of DNA double-strand break processing and regulation of histone H2B conserved C-terminal lysine ubiquitination. Predicted to be active in nucleus and site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes WDR70P1
Bonobo Pan paniscus WDR70P1
Gorilla Gorilla gorilla WDR70P1
Orangutan Pongo abelii WDR70P1
Gibbon Nomascus leucogenys FKBP1AP5
Green monkey Chlorocebus sabaeus FKBP1AP2
Crab-eating macaque Macaca fascicularis FKBP1AP1
Rhesus Macaca mulatta FKBP1AP2
Baboon Papio anubis FKBP1AP2
Golden snub-nosed monkey Rhinopithecus roxellana FKBP1AP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>WDR70P5
AACAAACAAATAACCAGTGGGAGGCAAAACAAGCTGAGACACTAACCCAGGACTACATCATCGCCCCTCATGTCTTGCCTATGTTCTGTGAGCCCCACGAACGGAGTACAAGGAAACAGCTAGAGAAGGACAGACTGGATCCCCTGAAGTTGCATAAACCTGAACCTCCTGTAGCAGACCCAGGTTGTGGTGGGACCCACAAGGGCACTCTTTCTTTCTATATTGTGAAGAACATTGCTTTGGACAAGACTGACGACCGTAATCCTTGGGAAGCCATTTTGCATCATGCCAAAGCGCAGAAGACAACCCATATTGGGTTTCTCCAACACATTCCAAGACTCAGCCCAGAATCATGTTTGGCCAAGTTGAATCTGATGATGAGGAAGCAAAGAATGAGCCAGAATGGAAAAAATGTAAAATTTGAAGAATCTCTTTTGAAAACTGTTTGTATGAGTAGGAGGGAAATGTGACAGGTTTGGGTTTTCTTTTTAATACTCATGAAATTAAAAATTCATTTTTATGAAAGACTGTGAGGACGTGGGAAATTGAAAACCCAAAGAAACAAAAAAAGTGTGTTTAAACCACGGACGATGCAGAACAAAAAAATGTCATTCCCACAACGTGCACATATAGTAGAGATGGAAATCTCATAGCAGCCGCCTGCCAGAATGGAAGCATGCAGATCTGGGACCGATATCTGACGGTTCATCCTAAGTTCAACTATAAACAGCCTCATTACTTGGGCACAGACACTTCTTGGCGTGACTTTTTCCTATGATGGTAATGTCCTTGCCTCTCGTGGAGGTGATGATTCGTTAAAATTATGGGACATCCGACAATTTAATAAGCACTTTTTTCAGCCTCGGGTCTTCCCACCATGTTCCCAATGATTGACTGCTGTTTCAGTCCAGATGATAAGCTCATAGTCACTGGTACGTCTGTTCAAAGGGGATGTGGCAGCGGCAAACTTGTTTGCCTTGAGCGTAGGACTTTCCAAAGGGTGTATGAAACAGACATCACAGACGCTGCCTGCGGCATCCAAGGCTGAACCAGATCATGGTTGGAACTGGAAATGATTGTCTAAAGTCTATTACAACCCCAACAAGAGTCAGAGAGGAGCAAAATTATATGTGGTTAAAACCCGGCGAAAGGGGA
>NM_001345998.2
GCAGTTGTTTGGGCTGTCCCTGTGGCTGGTTCTGGGGTGTGCGGCCAGCCATGGAGCGCTCTGGGCCCAGCGAAGTGACAGGCTCAGACGCGTCGGGACCGGACCCGCAGCTTGCGGTCACCATGGGCTTCACGGGGTTCGGTAAAAAAGCTCGCACATTTGACTTGGAAGCAATGTTTGAACAAACTCGAAGGACAGCTGTGGAAAGAAGTCGCAAAACACTGGCAAGAGAAAAAGAGGAAGAAATGAACAGAGAGAAAGAATTAAGAAGACAAAATGAAGATATTGAGCCAACATCCTCAAGATCAAATGTGGTCAGAGATTGCTCCAAATCATCTTCCAGGGATACGAGCAGCAGTGAAAGTGAACAGAGTTCTGACTCTTCTGATGATGAGTTAATTGGCCCTCCTTTACCCCCTAAAATGGTAGGAAAACCAGTTAATTTTATGGAGGAAGATATCCTCGGTCCTTTACCTCCACCTCTTAATgaagaagaagaagaagcagaggaagaagaagaggaagaggaggaagaggaaAATCCTGTTCACAAGATTCCTGACTCGCATGAGATAACGCTGAAGCATGGCACTAAAACAGTGTCTGCTTTGGGTCTGGATCCCTCAGGTGCCCGTTTGGTGACAGGAGGATATGACTATGATGTTAAGTTTTGGGATTTTGCTGGAATGGATGCTTCTTTTAAGGCATTTCGATCCCTTCAGCCCTGTGAGTGCCATCAGATCAAGTCATTACAGTATAGTAACACAGGAGACATGATTCTTGTTGTATCTGGAAGCTCTCAGGCCAAGGTGATTGACAGAGATGGTTTTGAAGTAATGGAATGTATAAAAGGAGACCAGTATATTGTGGACATGGCCAACACCAAGGGTCATACAGCAATGCTTCATACTGGCTCATGGCATCCCAAAATAAAGGGAGAATTTATGACTTGCTCAAATGATGCGACTGTGAGGACGTGGGAAGTTGAAAATCCAAAGAAGCAAAAAAGTGTGTTTAAACCACGGACGATGCAAGGCAAAAAAGTCATTCCCACTACGTGCACATATAGTAGAGATGGAAACCTCATAGCAGCTGCCTGCCAGAATGGAAGCATACAGATCTGGGACCGAAATTTGACTGTTCATCCTAAGTTCCACTATAAACAGGCTCATGACTCGGGCACAGACACTTCTTGCGTGACTTTTTCCTATGATGGTAATGTCCTTGCCTCTCGTGGAGGTGACGATTCATTAAAATTATGGGACATCCGACAATTTAATAAACCACTTTTTTCAGCCTCGGGTCTTCCCACCATGTTCCCAATGACTGACTGCTGTTTCAGTCCAGATGATAAGCTCATAGTCACTGGTACATCTATTCAAAGAGGATGTGGCAGCGGCAAACTTGTTTTCTTTGAGCGTAGGACTTTCCAAAGGGTGTATGAAATAGACATCACAGATGCGAGTGTTGTTCGCTGCCTGTGGCATCCAAAGCTGAACCAGATCATGGTTGGAACTGGAAATGGATTGGCTAAAGTCTATTACGACCCCAACAAGAGTCAGAGGGGAGCAAAATTATGTGTGGTTAAAACCCAGCGGAAGGCAAAACAAGCTGAGACTCTAACTCAGGACTACATCATCACCCCTCATGCCTTGCCTATGTTCCGTGAGCCCCGCCAACGGAGTACAAGGAAACAGCTGGAGAAGGACAGACTGGATCCCCTGAAGTCGCATAAACCTGAACCTCCTGTAGCAGGCCCAGGTCGTGGTGGCCGAGTTGGAACCCACGGGGGCACTCTCTCTTCCTATATTGTGAAGAACATTGCTTTGGACAAGACCGATGACAGTAATCCTCGGGAAGCCATTTTGCGTCATGCCAAAGCAGCAGAAGACAGCCCATATTGGGTTTCTCCAGCATATTCCAAGACTCAGCCCAAAACCATGTTTGCCCAAGTTGAATCTGATGATGAGGAAGCAAAGAATGAGCCAGAATGGAAAAAACGTAAAATTTGAAGAATCTCATTTGAGAGCTGTTTGCATGAGTGGGAGGGGTATGGGACAGGTTTGGGTTTTTTTTTTATGCTCATGAAATTAAAAATTCATTTTTATGAACAGGTTTTGTCCTTTGCATTATTGAACTGGTCAAAAGTTTGGTGGCTAGGCTTCACTAAAATTGTGCTTAAATTTTCTTACCTGCAACTATTAAACTGATTACAGATAAACAAGAAACAGATTCTTAGTCTATTACCAAGTACTTTAGGTATTTGGAAACTTTATTCAACAATTATTGGTCTTGTCCAGATTCTCATAACCTTAGAGAGGAAAATGTACATTAAGATGTGCATCTGTCTCTAGCAATTCTAGGAACATAATATAGAAATAGAGATCAAAAAGTTTAATGTTTCTGTATAATTTCACAACAGTTGTTTACATGACTGTAATTAATTAGGCTGAGTTCAAACCAAATACATTGCCATACTGGGAAAGAGCATTATCTCATTATCCTTCAatagcagaatacagtggttaagagttaggagtgggctttgaagtcagactcatgtggattcaagtcctggctttgctctttacttctgggtcatcttaagagagttatttaacttttcttttctagcctcagatgatgaaatagtacgtactttgcaggttcgtcagaagaattaaatgggacatgcctcacagagcatttagtacagtacctggaacacagtaaatgtataccaaatatttgctattTtaaaatagggctaatatttactttgcttggtttttatcagtattaaattagaaaggtatagaattgctttgtaaatgtaaagactaaacagaAGACATTAAAAATTATTCTAAAAAA

Publications

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