Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TOMM22P6
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Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr22). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:162486056-162486917  UCSC
Coordinates (T2T) chr3:165260856-165261718  UCSC
Coordinates (hg19) chr3:162203844-162204705  UCSC
Strand -
Parental Sequence NM_020243.5
Parental seq. overlap 709 bp
Parental seq. overlap (%) 34.6%
Genomic Region Intergenic
Retrocopy Summary TOMM22P6, located on chr3:162486056-162486917, is a retrocopy of the parental gene TOMM22. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TOMM22
Full Name translocase of outer mitochondrial membrane 22
Also known as 1C9-2|MST065|MSTP065|TOM22
Coordinate chr22:38681957-38685421
Strand +
Gene summary The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla LOC101129688P3
Gibbon Nomascus leucogenys TOMM22P4
Green monkey Chlorocebus sabaeus TOMM22P7
Crab-eating macaque Macaca fascicularis TOMM22P2
Rhesus Macaca mulatta TOMM22P2
Baboon Papio anubis TOMM22P2
Golden snub-nosed monkey Rhinopithecus roxellana TOMM22P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Orangutan Pongo abelii Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.050.1
log10(TPM+1)

Related Sequence

>TOMM22P6
GGAACCCCTGTCCCCAAACTAATTGCTCCCGAAAAGCAATGTGCAGAAGACTAAGTAGGAGCTGGAAGAGAATGATGAGGAGAAGCTAGATGAAAGCATGCCGAAGAGACCATGGGGCCTAACCAAGATATTTGCATATAGGGTCCAGTCTGCAGCCACAGCCACTTTTGATATCTCCCTTCTTATGGCTCAAAACATGCACAGGTTTTCCAGGTCATCCTTGTGGACTGGGGTTACTTCCAATATAATCCTCGTTTTTCATGTTGTCTTTGAGGCTGAGAAGTTACAAATGGAGCAACAGCAGATACTTCTGGGGCTGACATGGGGCTGTCAGGAGGCATGCCAGGGTCTCTAGCTCCACTTCCTGGAAAGATCTCAATTTTTACTGCTGTTGTTTGAGCTGTCTTGGTAGCAGAAGTTTGAAATTAAATTGTTTGAAATGCTGACTTTTTTGATTTTTTTTTAACTTTTGCACATTGATCTACCTAAACCTGGTGGGGAGAATTCTCCCTAGATTGTCTCATGGAGAAACTTAACTTGCAACTGTGCCCTCCACACTATACCGACTTACTTCTTCTGTCTTCACTCTGATAACAGAATGCAGTCTTGCAGATGGTTATTCCACCTCTGGCCACCCCACTCCTTTTACTAAATAGCTCCTAAGTGGAAGATCGCACTTGTCCATTGTGGCGTAGGAACTTATGTCAGTGGGAGGCATGTGCCGCTGGCCACTACTGGCTGCTTTATCTATTTTTATTTTTTTAGAATGGAGCTGTTGGGAAGGGATATGCACACAATATGAAATAGACAAAATGCATTACAACTGTAGTGTAAAGTGGCAACCATGAATCTCCATGTATGT
>NM_020243.5
GCTTCCGGTGTCCCCTACAGTCATGGCTGCCGCCGTCGCTGCTGCCGGTGCAGGGGAACCCCAGTCCCCGGACGAATTGCTCCCGAAAGGCGACGCGGAGAAGCCTgaggaggagctggaggaggacgacgatgaggagCTAGATGAGACCCTGTCGGAGAGACTATGGGGCCTGACGGAGATGTTTCCGGAGAGGGTCCGGTCCGCGGCCGGAGCCACTTTTGATCTTTCCCTCTTTGTGGCTCAGAAAATGTACAGGTTTTCCAGGGCAGCCTTGTGGATTGGGACCACTTCCTTTATGATCCTGGTTCTTCCCGTTGTCTTTGAGACGGAGAAGTTGCAAATGGagcaacagcagcaactgcagcagcggcagATACTTCTAGGACCTAACACAGGGCTCTCAGGAGGAATGCCAGGGGCTCTACCCTCACTTCCTGGAAAGATCTAGATTGTTATTGCTGTTTGAGCTGTCTCAGTGGGATAAGTTTGAAATTCAAGTGTTTGAACTGCTGATAATTTGGATTTTTTTTTTTTTTTAACTTTGGCACATTGATCTATCTAAACCTGGTGGGGAGAATTATCCCCACATTGTCTCATGGAAAGACTCAACTTGCAACTGTGCCCTCCACACTATCCTTACTTCTGTCTCCACTCTGATACCAGAGTGCAGCCATGCAGATGGTTATTCCAGCTCTGGTCACCCGACTCCTTTCACCAAATTGCTCCTAACTGGAAGATCTCACTTTCCCCTTGTGGGGTAGGAACCGATGCCAGTGGGAGGGATGTGCCCCTGACCATTAACGACTGttttttttttttttttttAAAGAATGGAGTTGTTGGGGCAGGACATGCACACAATGTGAAACAGACAAAATGCATTACACCTGTAGTGTAAAGTGGCCACTATGAATCCCTATGTATGAGAGGAGGGAGGCAGGCTGCAGCTTCAGCCACAGAATGGGGACTATGGAAGACAGCAGGAGCTCATTTCCTCTGCACATTTTGGCTGTTAGACCTGTGTGTGTGTTTAAAAAAAGAGAAGTCAGTGCTCACTTTTTGTATTTAAATATTAAAAATGATTCCAACTGAAAGTGTCATCCTAAGTACCTTGAAATGAGACCACGTCAGAGACATGTACTGCCCCTCACATTTTCTCACCTAAACCAGCAGCACCTCCATCTTAACAGCCATAGGCCCAAATTGTTTCCAAGTGAAAATTCATTTTTAGCCAAGTACTTCATAGCAATCTTTGCCCTGAATTTAGGCAGTCACTTTGAGATCCATCAGCCTAAAACAAAGGATTGGGTCTATGTACTTCTTTAGTCTATAATGACACTGTGTAATTATAAAGTATTTGTAGGGAATAACATAGTACTGATTTCTGGGGAATAGGGGAGGGGGACAGAAtttttttttttttttttttgcctgagatcaggtctcactggagtacagtggtgtcgtttgggttcactgcaacctcttacctcccctccaacttggcctcctgggtagctaagactacaggtacacgccaccgtgcccagctagtttcttttatttttggtagagtcagggtttcgccttgttgccccagatagtcttgaactcctgagttctagccatccacccgcctctggcccctcaaagtgctgggattataggcgtcacccaccacgcccagccAGAGtaagccttttgtgtgtttatcagatcaaccaacactacaatctaggtggtactgttcccattttacagaagaggaaacagccacagaaaggtaattgctcaaggctgcagagttaagtgctagacctggattcaaatccaggcagtccagctacagaACACTGCTGCTGTGCGCTCGGGATGGTGGGGCTGGGCCCAGGCCCGCTGGGTATACATGATCTTTCACTTGTTAACTAGGGAAAAACACTAGTCACCAGTGTGGTACAAACTTGTACTTAGGTGGATTCTTCAAATTGTCAAGATTAGTTTTTATAAATTAAAATAGACTGAAAAATG

Publications

PMID - Link Title
No publications available for this retrocopy