Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name THAP5P2
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:16275699-16276510  UCSC
Coordinates (T2T) chr3:16276916-16277727  UCSC
Coordinates (hg19) chr3:16317206-16318017  UCSC
Strand -
Parental Sequence NM_001130475.3
Parental seq. overlap 580 bp
Parental seq. overlap (%) 16.9%
Genomic Region Intragenic (OXNAD1)
Retrocopy Summary THAP5P2, located on chr3:16275699-16276510, is a retrocopy of the parental gene THAP5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name THAP5
Full Name THAP domain containing 5
Also known as -
Coordinate chr7:108562132-108569768
Strand -
Gene summary Enables protease binding activity. Involved in negative regulation of cell cycle and negative regulation of transcription by RNA polymerase II. Located in chromatin and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes THAP5P1
Bonobo Pan paniscus THAP5P1
Gorilla Gorilla gorilla THAP5P1
Orangutan Pongo abelii THAP5P1
Gibbon Nomascus leucogenys THAP5P1
Green monkey Chlorocebus sabaeus THAP5P1
Crab-eating macaque Macaca fascicularis THAP5P1
Rhesus Macaca mulatta THAP5P1
Baboon Papio anubis THAP5P1
Golden snub-nosed monkey Rhinopithecus roxellana THAP5P1
Marmoset Callithrix jacchus THAP5P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>THAP5P2
TCAAAATACATGTTAACTCTTAAACTAGTTAAACAAGATTAACTAGGAAACCAGAATCTACGTTGGAAACATCAGTTAACTAAAATATGGATATAGGTGCTTTTCACACATCTTTTGAGTATCTAAATTTTACAACTATTACTTTGATAATTTCAAATTCAGAAGGTATTCAACAGTCTTTGGAAACCCAAGAAGTGCTTGAAATAACTACCAATCATCTTGCTAATCCAAATTTTACAAATATTCCATGAAAATCAGGTCAGCACAGGATAATTCATTCTTATTTAGCACAATTAATCAAACAGTTGAAGAATTAAACACAAATAAATAATCTATTATTGCCATTTTTCAGATTGATGGGTTTCTAGTAAATACCAGTTACTATGTAGTGACCATTTCACTCCTGACTCTCTTGACATCAGACGGGGGATTTGATATTTAAAACAAAGTACAGTTCCAACAACTTTTTCCTCTGCCTGAAGACAATCAAGTAAAAGATCCTTCTTAAAAAAAAAAAAAATTCACAGAAGAAACAATTGGAAGATGAGAAAAAAGTATGCCTAAAAGCCAAATCAGAAAAATCACTTGTATTAAATGAGGCAAAGAAAAATATAGTTAACACAGATGTGCTCCCTGAACACGCAATTACTTGATTCATCTGCCTTGGTGAAGCCACTGGCTTCTAAAACCAAGAAGTATACAAAATACTTGTTAACt
>NM_001130475.3
AGACGAGGCGGCTTTCCCGGCAGAATGCTAGCGCAGGCGCAGGGGCTCGAGAGGCCTGGACCTGTGGCGCATCCTCAGTGAGGAGGGCCGCCCTGCATCCGTCGCCGGCCCCGGTCTCCAGGGGCCTCACCCGAGTCATGCCCCGCTATTGCGCAGCGATTTGTTGTAAGAACCGCCGGGGACGAAACAATAAAGACCGGAAGCTGAGTTTTTATCCATTTCCTCTACATGACAAAGAAAGACTGGAAAAGTGGTTAAAGAATATGAAGCGAGATTCATGGGTTCCCAGTAAATACCAGTTTCTATGTAGTGACCATTTTACTCCTGACTCTCTTGACATCAGATGGGGTATTCGATATTTAAAACAAACTGCAGTTCCAACAATATTTTCTTTGCCTGAAGACAATCAGGGAAAAGACCCTTCTAAAAAAAAATCCCAGAAGAAAAACTTGGAAGATGAGAAAGAAGTATGCCCAAAAGCCAAGTCAGAAGAATCATTTGTATTAAATGAGACAAAGAAAAATATAGTTAACACAGATGTGCCCCATCAACATCCAGAATTACTTCATTCATCTTCCTTGGTAAAGCCACCAGCTCCCAAAACAGGAAGTATACAAAATAACATGTTAACTCTTAATCTAGTTAAACAACATACTGGGAAACCAGAATCTACCTTGGAAACATCAGTTAACCAAGATACAGGTAGAGGTGGTTTTCACACATGTTTTGAGAATCTAAATTCTACAACTATTACTTTGACAACTTCAAATTCAGAAAGTATTCATCAATCTTTGGAAACTCAAGAAGTTCTTGAAGTAACTACCAGTCATCTTGCTAATCCAAACTTTACAAGTAATTCCATGGAAATAAAGTCAGCACAGGAAAATCCATTCTTATTCAGCACAATTAATCAAACAGTTGAAGAATTAAACACAAATAAAGAATCTGTTATTGCCATTTTTGTACCTGCTGAAAATTCTAAACCCTCAGTTAATTCTTTTATATCTGCACAAAAAGAAACCACGGAAATGGAAGACACAGACATTGAAGACTCCTTGTATAAGGATGTAGACTATGGGACAGAAGTTTTACAAATCGAACATTCTTACTGCAGACAAGATATAAATAAGGAACATCTTTGGCAGAAAGTCTCTAAGCTACATTCAAAGATAACTCTTCTAGAGTTAAAAGAGCAACAAACTCTAGGTAGATTGAAGTCTTTGGAAGCTCTTATAAGGCAGCTAAAGCAGGAAAACTGGCTATCTGAAGAAAACGTCAAGATTATAGAAAACCATTTTACAACATATGAAGTCACTATGATATAGAATAACTAGGTTTTAAAACTATGGCTGTTAAATAAGCTTTTTCCAGCCAAACCAAACTACATGTAAAGTGAACTGTTTCCTGTATAAAGTTCTCATCTTAATGAACCTATGAGAGTGTTGTAAAGTTATGAACTGTATCCTATTCTTGTAATACTTATTTAAGAAAAACCAGAGAGTTGGGCTGGAGAGAAAAGCAGTTTTATTACTTGATAATTTTCCAAATTAAAATTTAGCACATAGAAGGATTCAGTTATAACATGAGAAAACAAAGAAGTGTTCaaagagcacagactagaagtcaggttcaggaatcagtcctggttctaccactggcatatgacttgggcaagttacttatgattgtgcctcagtccctaatttgtaaaataagcacttactggatttgtaattggttatttatagtcccttccCTTTTTATTAAGATAATTCTATTAGAACACATTTTCTGTAAGATAATATATACGTAATACTAGAAGTTGGCTAGAATTTGATGATATTAACCATGTATTATTTTCAGTATTTATTGAATTCTGTGGTCTTTGACCTTTTGGCTATAGTTACATATTACAGTTATATTATCTGTAATAGAAAGGAAGATAAACttttttttttttttttttttttttttttttgagatggagtctcactctgtaacccaggctggagtgcagtggcctgatcttggctcactgcagcctctgcctcccgggttcaagtgattcttctgcctcagcttcccgagtagctgggattataggcacacaccaccacatccagcttatttttgtatttttagtagaaacggggtttcaccatgttggccgggctggcctcgaactcctgaccccaggtgatccacctaccttggcctcccaaagtgctgggattacaggcgtgagccaccgcgcctggccAAGATAGAACTTTTATAATTTTATTCCAGTTGAACTAAACTAAGGAACCACCCATTAGCCCAGTTCTTAGGAGAGGTACTTCAAACTTGAAAGAATATGTATTTCGGTAACTTATATGTGGCTAACCATCAAATACATAGTCATCTAAGCTAAACTTTCTGTATTTATACAGTTAAACTTATAAACCAAAAATTTTAATGAGGTTAATTTTAAATATATTTTAGAAATTACAGTTTGTATCTGTTTCTTAGTAGGTGTGGCCTTTAAAATATGTGCTTATTCATTGTTAAATTCCAGAATAATAGAGTAATACTTAATACTGTACATTCCCACTTACGTATATTTTATTAAAATTTATAAGCAAGAAATTATACATAAGTGGTCATGATCTTAGGGAGACAAAGAATTTCTCTTAGAAAAGAGAAGTAATGGTAATGTAAATAAAAATACTGTTTATATTCACATGATTTTAAGAAAACTGTAAAAGCAAAGATTTTGTAGTAATGACACAAATGTAACAAATAGATGTTTTCTTAAAATTGGCAGTCAGTATAATTATGTTTCTGCCtatgatgttgaggaagttgtatcagtctgattcttagttttttcatctgttaagtagaacgtactattacttaccttaaagagtggctttgagaattttgtaaggaacaaacatgtttttggttctggaatataggaggtgctcaataaaagttgactctGACTGGCAAATAATATTGTTTTGTAAATGCATGATGATTATTTTTGGCCATATTTGACTTAGTTTCATTAGGCTAATATTAATTGGTACTATATGAAAGTGAGTCAACTAATTATAAAAGATTAGAAATGTCTTAGGTGACGATGGGGGAAAAACTTAAAATTTTTGCATAAATTATGGGGAGATGATAGAGTTATTACAGTGTTATTAAGTATTCCTATGTTGCATTTTGCAAATACTTAATTTAATACAGATGAAAATAATCTTGAGTCACAATAAAGTAATGATATGTTAAGTTTCAACAGTGTACATTGTAGTAATTTTCTGAAAGTTACAGGTTCCTCAGAAAAAATTTAAACTAGCTTTATTTCTTTAATAAATTATAAGTAAAAGTTGA

Publications

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